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Items: 1 to 50 of 107

1.

A cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins.

Golec E, Rosberg R, Zhang E, Renström E, Blom AM, King BC.

FASEB J. 2019 Aug 14:fj201901007R. doi: 10.1096/fj.201901007R. [Epub ahead of print]

PMID:
31412214
2.

Physicians' gender bias in the diagnostic assessment of medically unexplained symptoms and its effect on patient-physician relations.

Claréus B, Renström EA.

Scand J Psychol. 2019 Aug;60(4):338-347. doi: 10.1111/sjop.12545. Epub 2019 May 23.

PMID:
31124165
3.

The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification.

Luan C, Ye Y, Singh T, Barghouth M, Eliasson L, Artner I, Zhang E, Renström E.

Commun Biol. 2019 Mar 15;2:106. doi: 10.1038/s42003-019-0351-4. eCollection 2019.

4.

The (Not So) Changing Man: Dynamic Gender Stereotypes in Sweden.

Gustafsson Sendén M, Klysing A, Lindqvist A, Renström EA.

Front Psychol. 2019 Jan 30;10:37. doi: 10.3389/fpsyg.2019.00037. eCollection 2019. Erratum in: Front Psychol. 2019 Apr 04;10:892.

5.

---Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1.

King BC, Renström E, Blom AM.

Autophagy. 2019 May;15(5):919-921. doi: 10.1080/15548627.2019.1580515. Epub 2019 Feb 20.

PMID:
30741587
6.

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model.

Edlund A, Barghouth M, Huhn M, Abels M, Esguerra J, Mollet I, Svedin E, Wendt A, Renstrom E, Zhang E, Wierup N, Scholte BJ, Flodström-Tullberg M, Eliasson L.

J Endocrinol. 2019 Feb 1. pii: JOE-18-0570.R1. doi: 10.1530/JOE-18-0570. [Epub ahead of print]

PMID:
30721137
7.

Patients' return-to-work expectancy relates to their beliefs about their physician's opinion regarding return to work volition and ability.

Claréus B, Renström EA.

J Pain Res. 2019 Jan 15;12:353-362. doi: 10.2147/JPR.S179061. eCollection 2019.

8.

Gender bias in assessment of future work ability among pain patients - an experimental vignette study of medical students' assessment.

Gustafsson Sendén M, Renström EA.

Scand J Pain. 2019 Apr 24;19(2):407-414. doi: 10.1515/sjpain-2018-0108.

PMID:
30653471
9.

MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets.

Singh T, Sarmiento L, Luan C, Prasad RB, Johansson J, Cataldo LR, Renström E, Soneji S, Cilio C, Artner I.

Genes (Basel). 2018 Dec 18;9(12). pii: E644. doi: 10.3390/genes9120644.

10.

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation.

King BC, Kulak K, Krus U, Rosberg R, Golec E, Wozniak K, Gomez MF, Zhang E, O'Connell DJ, Renström E, Blom AM.

Cell Metab. 2019 Jan 8;29(1):202-210.e6. doi: 10.1016/j.cmet.2018.09.009. Epub 2018 Oct 4.

PMID:
30293775
11.

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells.

Zhang E, Mohammed Al-Amily I, Mohammed S, Luan C, Asplund O, Ahmed M, Ye Y, Ben-Hail D, Soni A, Vishnu N, Bompada P, De Marinis Y, Groop L, Shoshan-Barmatz V, Renström E, Wollheim CB, Salehi A.

Cell Metab. 2019 Jan 8;29(1):64-77.e6. doi: 10.1016/j.cmet.2018.09.008. Epub 2018 Oct 4.

12.

Intestinal CART is a regulator of GIP and GLP-1 secretion and expression.

Shcherbina L, Lindqvist A, Thorén Fischer AH, Ahlqvist E, Zhang E, Falkmer SE, Renström E, Koffert J, Honka H, Wierup N.

Mol Cell Endocrinol. 2018 Nov 15;476:8-16. doi: 10.1016/j.mce.2018.04.002. Epub 2018 Apr 6.

PMID:
29627317
13.

Palmitoylation of Ca2+ channel subunit CaVβ2a induces pancreatic beta-cell toxicity via Ca2+ overload.

Kazim AS, Storm P, Zhang E, Renström E.

Biochem Biophys Res Commun. 2017 Sep 23;491(3):740-746. doi: 10.1016/j.bbrc.2017.07.117. Epub 2017 Jul 21.

PMID:
28739256
14.

Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans.

De Marinis Y, Sun J, Bompada P, Domènech Omella J, Luan C, Halu A, Renström E, Sharma A, Ridderstråle M.

Obesity (Silver Spring). 2017 Aug;25(8):1400-1409. doi: 10.1002/oby.21899. Epub 2017 Jun 28.

15.

The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.

Kulak K, Westermark GT, Papac-Milicevic N, Renström E, Blom AM, King BC.

Diabetologia. 2017 Aug;60(8):1522-1533. doi: 10.1007/s00125-017-4286-3. Epub 2017 May 12.

16.

Loss of α2δ-1 Calcium Channel Subunit Function Increases the Susceptibility for Diabetes.

Mastrolia V, Flucher SM, Obermair GJ, Drach M, Hofer H, Renström E, Schwartz A, Striessnig J, Flucher BE, Tuluc P.

Diabetes. 2017 Apr;66(4):897-907. doi: 10.2337/db16-0336. Epub 2017 Jan 23.

17.

C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity.

Sjölander J, Byman E, Kulak K, Nilsson SC, Zhang E, Krus U, Westermark GT, Storm P, King BC, Renström E, Blom AM.

J Biol Chem. 2016 Oct 7;291(41):21644-21655. Epub 2016 Aug 26.

18.

Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol.

Nagaraj V, Kazim AS, Helgeson J, Lewold C, Barik S, Buda P, Reinbothe TM, Wennmalm S, Zhang E, Renström E.

Mol Endocrinol. 2016 Oct;30(10):1059-1069. Epub 2016 Aug 17.

19.

CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.

Abels M, Riva M, Bennet H, Ahlqvist E, Dyachok O, Nagaraj V, Shcherbina L, Fred RG, Poon W, Sörhede-Winzell M, Fadista J, Lindqvist A, Kask L, Sathanoori R, Dekker-Nitert M, Kuhar MJ, Ahrén B, Wollheim CB, Hansson O, Tengholm A, Fex M, Renström E, Groop L, Lyssenko V, Wierup N.

Diabetologia. 2016 Sep;59(9):1928-37. doi: 10.1007/s00125-016-4020-6. Epub 2016 Jun 23.

PMID:
27338624
20.

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.

Ganic E, Singh T, Luan C, Fadista J, Johansson JK, Cyphert HA, Bennet H, Storm P, Prost G, Ahlenius H, Renström E, Stein R, Groop L, Fex M, Artner I.

Cell Rep. 2016 Mar 1;14(8):1991-2002. doi: 10.1016/j.celrep.2016.02.002. Epub 2016 Feb 18.

21.

HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.

Zhou Y, Oskolkov N, Shcherbina L, Ratti J, Kock KH, Su J, Martin B, Oskolkova MZ, Göransson O, Bacon J, Li W, Bucciarelli S, Cilio C, Brazma A, Thatcher B, Rung J, Wierup N, Renström E, Groop L, Hansson O.

Mol Cell Endocrinol. 2016 Jul 15;430:138-45. doi: 10.1016/j.mce.2016.01.027. Epub 2016 Feb 1.

PMID:
26845344
22.

Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis.

Merza M, Hartman H, Rahman M, Hwaiz R, Zhang E, Renström E, Luo L, Mörgelin M, Regner S, Thorlacius H.

Gastroenterology. 2015 Dec;149(7):1920-1931.e8. doi: 10.1053/j.gastro.2015.08.026. Epub 2015 Aug 22.

PMID:
26302488
23.

Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.

Nagaraj V, King B, Storm P, Vikman P, Ottosson-Laakso E, Blom AM, Renström E.

Biochem Biophys Res Commun. 2015 May 8;460(3):518-24. doi: 10.1016/j.bbrc.2015.03.062. Epub 2015 Mar 19.

24.

Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.

Tang Y, Axelsson AS, Spégel P, Andersson LE, Mulder H, Groop LC, Renström E, Rosengren AH.

Sci Transl Med. 2014 Oct 8;6(257):257ra139. doi: 10.1126/scitranslmed.3009934.

25.

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

Fadista J, Vikman P, Laakso EO, Mollet IG, Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB, Hansson KB, Finotello F, Uvebrant K, Ofori JK, Di Camillo B, Krus U, Cilio CM, Hansson O, Eliasson L, Rosengren AH, Renström E, Wollheim CB, Groop L.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9. doi: 10.1073/pnas.1402665111. Epub 2014 Sep 8.

26.

TCF7L2 is a master regulator of insulin production and processing.

Zhou Y, Park SY, Su J, Bailey K, Ottosson-Laakso E, Shcherbina L, Oskolkov N, Zhang E, Thevenin T, Fadista J, Bennet H, Vikman P, Wierup N, Fex M, Rung J, Wollheim C, Nobrega M, Renström E, Groop L, Hansson O.

Hum Mol Genet. 2014 Dec 15;23(24):6419-31. doi: 10.1093/hmg/ddu359. Epub 2014 Jul 11.

27.

The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.

Krus U, King BC, Nagaraj V, Gandasi NR, Sjölander J, Buda P, Garcia-Vaz E, Gomez MF, Ottosson-Laakso E, Storm P, Fex M, Vikman P, Zhang E, Barg S, Blom AM, Renström E.

Cell Metab. 2014 May 6;19(5):883-90. doi: 10.1016/j.cmet.2014.03.001. Epub 2014 Apr 10.

28.

Dynamic magnetic fields remote-control apoptosis via nanoparticle rotation.

Zhang E, Kircher MF, Koch M, Eliasson L, Goldberg SN, Renström E.

ACS Nano. 2014 Apr 22;8(4):3192-201. doi: 10.1021/nn406302j. Epub 2014 Mar 20.

29.

Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA.

Chen D, Zuo D, Luan C, Liu M, Na M, Ran L, Sun Y, Persson A, Englund E, Salford LG, Renström E, Fan X, Zhang E.

PLoS One. 2014 Jan 29;9(1):e87281. doi: 10.1371/journal.pone.0087281. eCollection 2014.

30.

Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.

Buda P, Reinbothe T, Nagaraj V, Mahdi T, Luan C, Tang Y, Axelsson AS, Li D, Rosengren AH, Renström E, Zhang E.

PLoS One. 2013 May 30;8(5):e64462. doi: 10.1371/journal.pone.0064462. Print 2013.

31.

Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.

Taneera J, Fadista J, Ahlqvist E, Zhang M, Wierup N, Renström E, Groop L.

Mol Cell Endocrinol. 2013 Aug 15;375(1-2):35-42. doi: 10.1016/j.mce.2013.05.003. Epub 2013 May 22.

PMID:
23707792
32.

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans.

Jonsson A, Ladenvall C, Ahluwalia TS, Kravic J, Krus U, Taneera J, Isomaa B, Tuomi T, Renström E, Groop L, Lyssenko V.

Diabetes. 2013 Aug;62(8):2978-83. doi: 10.2337/db12-1627. Epub 2013 Apr 4.

33.

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.

Reinbothe TM, Alkayyali S, Ahlqvist E, Tuomi T, Isomaa B, Lyssenko V, Renström E.

Diabetologia. 2013 Feb;56(2):340-9. doi: 10.1007/s00125-012-2758-z. Epub 2012 Nov 15.

PMID:
23229155
34.

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.

Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH.

Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009.

35.

Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.

Renström E.

Diabetologia. 2012 Oct;55(10):2559-2561. doi: 10.1007/s00125-012-2659-1. Epub 2012 Aug 5.

36.

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.

Hindy G, Sonestedt E, Ericson U, Jing XJ, Zhou Y, Hansson O, Renström E, Wirfält E, Orho-Melander M.

Diabetologia. 2012 Oct;55(10):2646-2654. doi: 10.1007/s00125-012-2634-x. Epub 2012 Jul 11.

37.

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.

Taneera J, Lang S, Sharma A, Fadista J, Zhou Y, Ahlqvist E, Jonsson A, Lyssenko V, Vikman P, Hansson O, Parikh H, Korsgren O, Soni A, Krus U, Zhang E, Jing XJ, Esguerra JL, Wollheim CB, Salehi A, Rosengren A, Renström E, Groop L.

Cell Metab. 2012 Jul 3;16(1):122-34. doi: 10.1016/j.cmet.2012.06.006.

38.

Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.

Yang BT, Dayeh TA, Volkov PA, Kirkpatrick CL, Malmgren S, Jing X, Renström E, Wollheim CB, Nitert MD, Ling C.

Mol Endocrinol. 2012 Jul;26(7):1203-12. doi: 10.1210/me.2012-1004. Epub 2012 May 8.

39.

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.

Taneera J, Jin Z, Jin Y, Muhammed SJ, Zhang E, Lang S, Salehi A, Korsgren O, Renström E, Groop L, Birnir B.

Diabetologia. 2012 Jul;55(7):1985-94. doi: 10.1007/s00125-012-2548-7. Epub 2012 Apr 27.

40.

The adult human brain harbors multipotent perivascular mesenchymal stem cells.

Paul G, Özen I, Christophersen NS, Reinbothe T, Bengzon J, Visse E, Jansson K, Dannaeus K, Henriques-Oliveira C, Roybon L, Anisimov SV, Renström E, Svensson M, Haegerstrand A, Brundin P.

PLoS One. 2012;7(4):e35577. doi: 10.1371/journal.pone.0035577. Epub 2012 Apr 16.

41.

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.

Rosengren AH, Braun M, Mahdi T, Andersson SA, Travers ME, Shigeto M, Zhang E, Almgren P, Ladenvall C, Axelsson AS, Edlund A, Pedersen MG, Jonsson A, Ramracheya R, Tang Y, Walker JN, Barrett A, Johnson PR, Lyssenko V, McCarthy MI, Groop L, Salehi A, Gloyn AL, Renström E, Rorsman P, Eliasson L.

Diabetes. 2012 Jul;61(7):1726-33. doi: 10.2337/db11-1516. Epub 2012 Apr 9.

42.

Truncated and full-length thioredoxin-1 have opposing activating and inhibitory properties for human complement with relevance to endothelial surfaces.

King BC, Nowakowska J, Karsten CM, Köhl J, Renström E, Blom AM.

J Immunol. 2012 Apr 15;188(8):4103-12. doi: 10.4049/jimmunol.1101295. Epub 2012 Mar 19.

43.

Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.

Sjölander J, Westermark GT, Renström E, Blom AM.

J Biol Chem. 2012 Mar 30;287(14):10824-33. doi: 10.1074/jbc.M111.244285. Epub 2012 Feb 13.

44.

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.

Zhou Y, Zhang E, Berggreen C, Jing X, Osmark P, Lang S, Cilio CM, Göransson O, Groop L, Renström E, Hansson O.

Hum Mol Genet. 2012 Jan 1;21(1):196-207. doi: 10.1093/hmg/ddr454. Epub 2011 Sep 30.

PMID:
21965303
45.

Autologous hematopoietic stem cell transplantation in type 1-diabetes.

Rosengren AH, Renström E.

Islets. 2009 Jul-Aug;1(1):81-3. doi: 10.4161/isl.1.1.8817. Review.

PMID:
21084854
46.

Bone marrow transplantation stimulates pancreatic β-cell replication after tissue damage.

Rosengren AH, Taneera J, Rymo S, Renström E.

Islets. 2009 Jul-Aug;1(1):10-8. doi: 10.4161/isl.1.1.8529.

PMID:
21084844
47.

Response to Jentsch et al.

Renström E.

Cell Metab. 2010 Oct 6;12(4):309. doi: 10.1016/j.cmet.2010.09.003. Epub 2010 Oct 5. No abstract available.

48.

Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes.

Hansson O, Zhou Y, Renström E, Osmark P.

Curr Diab Rep. 2010 Dec;10(6):444-51. doi: 10.1007/s11892-010-0149-8. Review.

PMID:
20878273
49.

GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.

De Marinis YZ, Salehi A, Ward CE, Zhang Q, Abdulkader F, Bengtsson M, Braha O, Braun M, Ramracheya R, Amisten S, Habib AM, Moritoh Y, Zhang E, Reimann F, Rosengren A, Shibasaki T, Gribble F, Renström E, Seino S, Eliasson L, Rorsman P.

Cell Metab. 2010 Jun 9;11(6):543-553. doi: 10.1016/j.cmet.2010.04.007.

50.

Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.

De Marinis YZ, Zhang E, Amisten S, Taneera J, Renström E, Rorsman P, Eliasson L.

Diabetologia. 2010 Apr;53(4):717-29. doi: 10.1007/s00125-009-1635-x. Epub 2009 Dec 18.

PMID:
20020096

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