Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86


Polymeric nanobiotics as a novel treatment for mycobacterial infections.

Batalha IL, Bernut A, Schiebler M, Ouberai MM, Passemar C, Klapholz C, Kinna S, Michel S, Sader K, Castro-Hartmann P, Renshaw SA, Welland ME, Floto RA.

J Control Release. 2019 Oct 21;314:116-124. doi: 10.1016/j.jconrel.2019.10.009. [Epub ahead of print]


Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation.

Rahman A, Henry KM, Herman KD, Thompson AA, Isles HM, Tulotta C, Sammut D, Rougeot JJ, Khoshaein N, Reese AE, Higgins K, Tabor C, Sabroe I, Zuercher WJ, Savage CO, Meijer AH, Whyte MK, Dockrell DH, Renshaw SA, Prince LR.

Elife. 2019 Oct 15;8. pii: e50990. doi: 10.7554/eLife.50990.


The CXCL12/CXCR4 Signaling Axis Retains Neutrophils at Inflammatory Sites in Zebrafish.

Isles HM, Herman KD, Robertson AL, Loynes CA, Prince LR, Elks PM, Renshaw SA.

Front Immunol. 2019 Jul 31;10:1784. doi: 10.3389/fimmu.2019.01784. eCollection 2019.


A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase.

Buchan KD, Prajsnar TK, Ogryzko NV, de Jong NWM, van Gent M, Kolata J, Foster SJ, van Strijp JAG, Renshaw SA.

PLoS One. 2019 Apr 19;14(4):e0215592. doi: 10.1371/journal.pone.0215592. eCollection 2019.


15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

Evans RJ, Pline K, Loynes CA, Needs S, Aldrovandi M, Tiefenbach J, Bielska E, Rubino RE, Nicol CJ, May RC, Krause HM, O'Donnell VB, Renshaw SA, Johnston SA.

PLoS Pathog. 2019 Mar 28;15(3):e1007597. doi: 10.1371/journal.ppat.1007597. eCollection 2019 Mar.


CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses.

Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann JL, Floto RA, Renshaw SA, Kremer L.

Cell Rep. 2019 Feb 12;26(7):1828-1840.e4. doi: 10.1016/j.celrep.2019.01.071.


Staphylococcus aureus: setting its sights on the human innate immune system.

Buchan KD, Foster SJ, Renshaw SA.

Microbiology. 2019 Apr;165(4):367-385. doi: 10.1099/mic.0.000759. Epub 2019 Jan 9.


A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models.

Hamilton N, Sabroe I, Renshaw SA.

Version 2. F1000Res. 2018 May 15 [revised 2018 Jan 1];7:594. doi: 10.12688/f1000research.14507.2. eCollection 2018.


Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish.

Ogryzko NV, Lewis A, Wilson HL, Meijer AH, Renshaw SA, Elks PM.

J Immunol. 2019 Jan 15;202(2):494-502. doi: 10.4049/jimmunol.1801139. Epub 2018 Dec 14.


Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF.

Weatherley ND, Stewart NJ, Chan HF, Austin M, Smith LJ, Collier G, Rao M, Marshall H, Norquay G, Renshaw SA, Bianchi SM, Wild JM.

Thorax. 2019 May;74(5):500-502. doi: 10.1136/thoraxjnl-2018-211851. Epub 2018 Nov 2.


PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.

Loynes CA, Lee JA, Robertson AL, Steel MJ, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA.

Sci Adv. 2018 Sep 5;4(9):eaar8320. doi: 10.1126/sciadv.aar8320. eCollection 2018 Sep.


Human skin commensals augment Staphylococcus aureus pathogenesis.

Boldock E, Surewaard BGJ, Shamarina D, Na M, Fei Y, Ali A, Williams A, Pollitt EJG, Szkuta P, Morris P, Prajsnar TK, McCoy KD, Jin T, Dockrell DH, van Strijp JAG, Kubes P, Renshaw SA, Foster SJ.

Nat Microbiol. 2018 Aug;3(8):881-890. doi: 10.1038/s41564-018-0198-3. Epub 2018 Jul 16.


Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics.

Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ.

Methods Mol Biol. 2018;1736:147-156. doi: 10.1007/978-1-4939-7638-6_14.


The triune of intestinal microbiome, genetics and inflammatory status and its impact on the healing of lower gastrointestinal anastomoses.

Lee JA, Chico TJA, Renshaw SA.

FEBS J. 2018 Apr;285(7):1212-1225. doi: 10.1111/febs.14346. Epub 2017 Dec 22. Review.


Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood.

Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ.

Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17. Print 2017 Nov.


Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis.

Salamaga B, Prajsnar TK, Jareño-Martinez A, Willemse J, Bewley MA, Chau F, Ben Belkacem T, Meijer AH, Dockrell DH, Renshaw SA, Mesnage S.

PLoS Pathog. 2017 Jul 24;13(7):e1006526. doi: 10.1371/journal.ppat.1006526. eCollection 2017 Jul.


Expression and regulation of drug transporters in vertebrate neutrophils.

Foulkes MJ, Henry KM, Rougeot J, Hooper-Greenhill E, Loynes CA, Jeffrey P, Fleming A, Savage CO, Meijer AH, Jones S, Renshaw SA.

Sci Rep. 2017 Jul 10;7(1):4967. doi: 10.1038/s41598-017-04785-4.


NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival.

Prince LR, Prosseda SD, Higgins K, Carlring J, Prestwich EC, Ogryzko NV, Rahman A, Basran A, Falciani F, Taylor P, Renshaw SA, Whyte MKB, Sabroe I.

Blood. 2017 Aug 24;130(8):1014-1025. doi: 10.1182/blood-2017-03-770164. Epub 2017 Jun 21.


Performance of a Web-based Method for Generating Synoptic Reports.

Renshaw MA, Renshaw SA, Mena-Allauca M, Carrion PP, Mei X, Narciandi A, Gould EW, Renshaw AA.

J Pathol Inform. 2017 Mar 10;8:13. doi: 10.4103/jpi.jpi_91_16. eCollection 2017.


Targeting Neutrophilic Inflammation Using Polymersome-Mediated Cellular Delivery.

Robertson JD, Ward JR, Avila-Olias M, Battaglia G, Renshaw SA.

J Immunol. 2017 May 1;198(9):3596-3604. doi: 10.4049/jimmunol.1601901. Epub 2017 Mar 13.


Zebrafish screens for new colitis treatments - a bottom-up approach.

Lee JA, Renshaw SA.

FEBS J. 2017 Feb;284(3):399-401. doi: 10.1111/febs.14005.


Purification of Nanoparticles by Size and Shape.

Robertson JD, Rizzello L, Avila-Olias M, Gaitzsch J, Contini C, Magoń MS, Renshaw SA, Battaglia G.

Sci Rep. 2016 Jun 8;6:27494. doi: 10.1038/srep27494.


Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.

Robertson AL, Ogryzko NV, Henry KM, Loynes CA, Foulkes MJ, Meloni MM, Wang X, Ford C, Jackson M, Ingham PW, Wilson HL, Farrow SN, Solari R, Flower RJ, Jones S, Whyte MK, Renshaw SA.

Dis Model Mech. 2016 Jun 1;9(6):621-32. doi: 10.1242/dmm.024935. Epub 2016 Apr 14.


Reverse Migration of Neutrophils: Where, When, How, and Why?

Nourshargh S, Renshaw SA, Imhof BA.

Trends Immunol. 2016 May;37(5):273-286. doi: 10.1016/ Epub 2016 Apr 4. Review.


Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection.

Bojarczuk A, Miller KA, Hotham R, Lewis A, Ogryzko NV, Kamuyango AA, Frost H, Gibson RH, Stillman E, May RC, Renshaw SA, Johnston SA.

Sci Rep. 2016 Feb 18;6:21489. doi: 10.1038/srep21489.


Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models.

Elks PM, Renshaw SA, Meijer AH, Walmsley SR, van Eeden FJ.

Dis Model Mech. 2015 Nov;8(11):1349-60. doi: 10.1242/dmm.021865. Review.


Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death.

Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O.

Hum Mol Genet. 2015 Dec 1;24(23):6640-52. doi: 10.1093/hmg/ddv369. Epub 2015 Sep 16.


Defining the phenotype of neutrophils following reverse migration in zebrafish.

Ellett F, Elks PM, Robertson AL, Ogryzko NV, Renshaw SA.

J Leukoc Biol. 2015 Dec;98(6):975-81. doi: 10.1189/jlb.3MA0315-105R. Epub 2015 Jun 12.


Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers.

Messad N, Prajsnar TK, Lina G, O'Callaghan D, Foster SJ, Renshaw SA, Skaar EP, Bes M, Dunyach-Remy C, Vandenesch F, Sotto A, Lavigne JP.

Diabetes. 2015 Aug;64(8):2991-5. doi: 10.2337/db15-0031. Epub 2015 Apr 21.


Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

Schiebler M, Brown K, Hegyi K, Newton SM, Renna M, Hepburn L, Klapholz C, Coulter S, Obregón-Henao A, Henao Tamayo M, Basaraba R, Kampmann B, Henry KM, Burgon J, Renshaw SA, Fleming A, Kay RR, Anderson KE, Hawkins PT, Ordway DJ, Rubinsztein DC, Floto RA.

EMBO Mol Med. 2015 Feb;7(2):127-39. doi: 10.15252/emmm.201404137.


Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus.

Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA.

Science. 2014 Oct 31;346(6209):641-646. doi: 10.1126/science.1258705.


Tnfa signaling through tnfr2 protects skin against oxidative stress-induced inflammation.

Candel S, de Oliveira S, López-Muñoz A, García-Moreno D, Espín-Palazón R, Tyrkalska SD, Cayuela ML, Renshaw SA, Corbalán-Vélez R, Vidal-Abarca I, Tsai HJ, Meseguer J, Sepulcre MP, Mulero V.

PLoS Biol. 2014 May 6;12(5):e1001855. doi: 10.1371/journal.pbio.1001855. eCollection 2014 May.


pH-sensitive tubular polymersomes: formation and applications in cellular delivery.

Robertson JD, Yealland G, Avila-Olias M, Chierico L, Bandmann O, Renshaw SA, Battaglia G.

ACS Nano. 2014 May 27;8(5):4650-61. doi: 10.1021/nn5004088. Epub 2014 Apr 29.


The IL-1 family in fish: swimming through the muddy waters of inflammasome evolution.

Ogryzko NV, Renshaw SA, Wilson HL.

Dev Comp Immunol. 2014 Sep;46(1):53-62. doi: 10.1016/j.dci.2014.03.008. Epub 2014 Mar 29. Review.


Clonal expansion during Staphylococcus aureus infection dynamics reveals the effect of antibiotic intervention.

McVicker G, Prajsnar TK, Williams A, Wagner NL, Boots M, Renshaw SA, Foster SJ.

PLoS Pathog. 2014 Feb 27;10(2):e1003959. doi: 10.1371/journal.ppat.1003959. eCollection 2014 Feb.


A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.

Robertson AL, Holmes GR, Bojarczuk AN, Burgon J, Loynes CA, Chimen M, Sawtell AK, Hamza B, Willson J, Walmsley SR, Anderson SR, Coles MC, Farrow SN, Solari R, Jones S, Prince LR, Irimia D, Rainger GE, Kadirkamanathan V, Whyte MK, Renshaw SA.

Sci Transl Med. 2014 Feb 26;6(225):225ra29. doi: 10.1126/scitranslmed.3007672.


Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.

Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA.

J Immunol. 2014 Feb 15;192(4):1796-805. doi: 10.4049/jimmunol.1300087. Epub 2014 Jan 15.


The impact of template format on the completeness of surgical pathology reports.

Renshaw SA, Mena-Allauca M, Touriz M, Renshaw A, Gould EW.

Arch Pathol Lab Med. 2014 Jan;138(1):121-4. doi: 10.5858/arpa.2012-0733-OA.


Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.

Elks PM, Brizee S, van der Vaart M, Walmsley SR, van Eeden FJ, Renshaw SA, Meijer AH.

PLoS Pathog. 2013;9(12):e1003789. doi: 10.1371/journal.ppat.1003789. Epub 2013 Dec 19.


Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library.

Wang X, Robertson AL, Li J, Chai RJ, Haishan W, Sadiku P, Ogryzko NV, Everett M, Yoganathan K, Luo HR, Renshaw SA, Ingham PW.

Dis Model Mech. 2014 Jan;7(1):163-9. doi: 10.1242/dmm.012047. Epub 2013 Nov 28.


Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response.

Ogryzko NV, Hoggett EE, Solaymani-Kohal S, Tazzyman S, Chico TJ, Renshaw SA, Wilson HL.

Dis Model Mech. 2014 Feb;7(2):259-64. doi: 10.1242/dmm.013029. Epub 2013 Nov 7.


Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR.

Blood. 2014 Jan 16;123(3):366-76. doi: 10.1182/blood-2013-05-500207. Epub 2013 Nov 6.


A Bayesian framework for identifying cell migration dynamics.

Holmes GR, Anderson SR, Dixon G, Renshaw SA, Kadirkamanathan V.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:3455-8. doi: 10.1109/EMBC.2013.6610285.


PhagoSight: an open-source MATLAB® package for the analysis of fluorescent neutrophil and macrophage migration in a zebrafish model.

Henry KM, Pase L, Ramos-Lopez CF, Lieschke GJ, Renshaw SA, Reyes-Aldasoro CC.

PLoS One. 2013 Aug 30;8(8):e72636. doi: 10.1371/journal.pone.0072636. eCollection 2013.


Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis.

Prajsnar TK, Renshaw SA, Ogryzko NV, Foster SJ, Serror P, Mesnage S.

Infect Immun. 2013 Nov;81(11):4271-9. doi: 10.1128/IAI.00976-13. Epub 2013 Sep 3.


Cxcl8 (IL-8) mediates neutrophil recruitment and behavior in the zebrafish inflammatory response.

de Oliveira S, Reyes-Aldasoro CC, Candel S, Renshaw SA, Mulero V, Calado A.

J Immunol. 2013 Apr 15;190(8):4349-59. doi: 10.4049/jimmunol.1203266. Epub 2013 Mar 18.


Zebrafish as a model for the study of neutrophil biology.

Henry KM, Loynes CA, Whyte MK, Renshaw SA.

J Leukoc Biol. 2013 Oct;94(4):633-42. doi: 10.1189/jlb.1112594. Epub 2013 Mar 5. Review.


Incremental shuttle walk test in the assessment of patients with obstructive sleep apnea-hypopnea syndrome.

Billings CG, Aung T, Renshaw SA, Bianchi SM.

J Sleep Res. 2013 Aug;22(4):471-7. doi: 10.1111/jsr.12037. Epub 2013 Feb 21.


Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo.

Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Vander Heiden MG, Goessling W, North TE.

Blood. 2013 Mar 28;121(13):2483-93. doi: 10.1182/blood-2012-12-471201. Epub 2013 Jan 22.


The addition of RPMI significantly improves the cellularity of cerebrospinal fluid cytology specimens over time.

Renshaw SA, Gupta S, Campos M, Hodes L, Renshaw AA, Gould EW.

Cancer Cytopathol. 2013 May;121(5):271-4. doi: 10.1002/cncy.21243. Epub 2012 Nov 6.

Supplemental Content

Loading ...
Support Center