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Items: 1 to 50 of 255

1.

Distribution of Brown Adipose Tissue Radiodensity in Young Adults: Implications for Cold [18F]FDG-PET/CT Analyses.

Martinez-Tellez B, Sanchez-Delgado G, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Mol Imaging Biol. 2019 May 30. doi: 10.1007/s11307-019-01381-y. [Epub ahead of print]

PMID:
31147900
2.

The role of inflammation in the association between overall and visceral adiposity and subclinical atherosclerosis.

Christen T, Trompet S, Rensen PCN, Willems van Dijk K, Lamb HJ, Jukema JW, Rosendaal FR, le Cessie S, de Mutsert R.

Nutr Metab Cardiovasc Dis. 2019 Jul;29(7):728-735. doi: 10.1016/j.numecd.2019.03.010. Epub 2019 Mar 28.

PMID:
31138500
3.

Time-restricted feeding improves adaptation to chronically alternating light-dark cycles.

Schilperoort M, van den Berg R, Dollé MET, van Oostrom CTM, Wagner K, Tambyrajah LL, Wackers P, Deboer T, Hulsegge G, Proper KI, van Steeg H, Roenneberg T, Biermasz NR, Rensen PCN, Kooijman S, van Kerkhof LWM.

Sci Rep. 2019 May 27;9(1):7874. doi: 10.1038/s41598-019-44398-7.

4.

Supraclavicular skin temperature measured by iButtons and 18F-fluorodeoxyglucose uptake by brown adipose tissue in adults.

Martinez-Tellez B, Garcia-Rivero Y, Sanchez-Delgado G, Xu H, Amaro-Gahete FJ, Acosta FM, Rensen PCN, Boon MR, Llamas-Elvira JM, Ruiz JR.

J Therm Biol. 2019 May;82:178-185. doi: 10.1016/j.jtherbio.2019.04.006. Epub 2019 Apr 16.

5.

The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses.

Bos MM, van Heemst D, Donga E, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, Noordam R.

J Clin Med. 2019 May 15;8(5). pii: E682. doi: 10.3390/jcm8050682.

6.

Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction.

Vrieling F, Wilson L, Rensen PCN, Walzl G, Ottenhoff THM, Joosten SA.

PLoS Pathog. 2019 Apr 18;15(4):e1007724. doi: 10.1371/journal.ppat.1007724. eCollection 2019 Apr.

7.

Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice.

Thiem K, Hoeke G, van den Berg S, Hijmans A, Jacobs CWM, Zhou E, Mol IM, Mouktaroudi M, Bussink J, Kanneganti TD, Lutgens E, Stienstra R, Tack CJ, Netea MG, Rensen PCN, Berbée JFP, van Diepen JA.

Sci Rep. 2019 Mar 13;9(1):4337. doi: 10.1038/s41598-019-40663-x.

8.

Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression.

Worthmann A, Schlein C, Berbée JFP, Rensen PCN, Heeren J, Bartelt A.

Nutrients. 2019 Feb 23;11(2). pii: E463. doi: 10.3390/nu11020463.

9.

[18F]BODIPY-triglyceride-containing chylomicron-like particles as an imaging agent for brown adipose tissue in vivo.

Paulus A, Drude N, Nascimento EBM, Buhl EM, Berbée JFP, Rensen PCN, van Marken Lichtenbelt WD, Mottaghy FM, Bauwens M.

Sci Rep. 2019 Feb 25;9(1):2706. doi: 10.1038/s41598-019-39561-z.

10.

High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.

Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR.

Front Physiol. 2019 Jan 10;9:1913. doi: 10.3389/fphys.2018.01913. eCollection 2018.

11.

Evidence of high 18 F-fluorodeoxyglucose uptake in the subcutaneous adipose tissue of the dorsocervical area in young adults.

Martinez-Tellez B, Sanchez-Delgado G, Alcantara JMA, Acosta FM, Amaro-Gahete FJ, Osuna-Prieto FJ, Perez-Bey A, Jimenez-Pavon D, Llamas-Elvira JM, Gil A, Aguilera CM, Rensen PCN, Ruiz JR.

Exp Physiol. 2019 Feb;104(2):168-173. doi: 10.1113/EP087428. Epub 2018 Dec 18.

PMID:
30468689
12.

Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice.

Nahon JE, Hoekstra M, van Harmelen V, Rensen PCN, Willems van Dijk K, Kooijman S, Van Eck M.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):494-501. doi: 10.1016/j.bbadis.2018.11.009. Epub 2018 Nov 15.

PMID:
30448542
13.

Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile.

Blauw LL, Noordam R, Soidinsalo S, Blauw CA, Li-Gao R, de Mutsert R, Berbée JFP, Wang Y, van Heemst D, Rosendaal FR, Jukema JW, Mook-Kanamori DO, Würtz P, Willems van Dijk K, Rensen PCN.

Eur J Hum Genet. 2019 Mar;27(3):422-431. doi: 10.1038/s41431-018-0301-5. Epub 2018 Nov 12.

PMID:
30420679
14.

Androgens modulate glucocorticoid receptor activity in adipose tissue and liver.

Spaanderman DCE, Nixon M, Buurstede JC, Sips HC, Schilperoort M, Kuipers EN, Backer EA, Kooijman S, Rensen PCN, Homer NZM, Walker BR, Meijer OC, Kroon J.

J Endocrinol. 2018 Oct 1. pii: JOE-18-0503.R1. doi: 10.1530/JOE-18-0503. [Epub ahead of print]

PMID:
30400038
15.

Effect of L-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study.

Boon MR, Hanssen MJW, Brans B, Hülsman CJM, Hoeks J, Nahon KJ, Bakker C, van Klinken JB, Havekes B, Schaart G, Jazet IM, Rensen PCN, van Marken Lichtenbelt WD.

Diabetologia. 2019 Jan;62(1):112-122. doi: 10.1007/s00125-018-4752-6. Epub 2018 Oct 30.

16.

Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [18F]FDG uptake in young adults.

Martinez-Tellez B, Xu H, Sanchez-Delgado G, Acosta FM, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Am J Physiol Regul Integr Comp Physiol. 2018 Dec 1;315(6):R1281-R1288. doi: 10.1152/ajpregu.00238.2018. Epub 2018 Oct 26.

PMID:
30365352
17.

Associations of sleep duration and quality with serum and hepatic lipids: The Netherlands Epidemiology of Obesity Study.

Bos MM, Noordam R, van den Berg R, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, van Heemst D.

J Sleep Res. 2018 Oct 15:e12776. doi: 10.1111/jsr.12776. [Epub ahead of print]

PMID:
30324729
18.

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis.

Trinder M, Genga KR, Kong HJ, Blauw LL, Lo C, Li X, Cirstea M, Wang Y, Rensen PCN, Russell JA, Walley KR, Boyd JH, Brunham LR.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):854-862. doi: 10.1164/rccm.201806-1157OC.

PMID:
30321485
19.

Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice.

Koorneef LL, van den Heuvel JK, Kroon J, Boon MR, 't Hoen PAC, Hettne KM, van de Velde NM, Kolenbrander KB, Streefland TCM, Mol IM, Sips HCM, Kielbasa SM, Mei H, Belanoff JK, Pereira AM, Oosterveer MH, Hunt H, Rensen PCN, Meijer OC.

Endocrinology. 2018 Dec 1;159(12):3925-3936. doi: 10.1210/en.2018-00671.

PMID:
30321321
20.

The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors?

Bos MM, Noordam R, Blauw GJ, Slagboom PE, Rensen PCN, van Heemst D.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):99-107. doi: 10.1093/gerona/gly226.

PMID:
30321297
21.

IDOL in metabolic, neurodegenerative and cardiovascular disease.

van Loon NM, Rensen PCN, Zelcer N.

Aging (Albany NY). 2018 Oct 14;10(11):3042-3043. doi: 10.18632/aging.101597. No abstract available.

22.

Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women.

Dekker SA, Noordam R, Biermasz NR, de Roos A, Lamb HJ, Rosendaal FR, Rensen PCN, van Heemst D, de Mutsert R.

Obesity (Silver Spring). 2018 Oct;26(10):1651-1658. doi: 10.1002/oby.22289.

PMID:
30277027
23.

Effect of sitagliptin on energy metabolism and brown adipose tissue in overweight individuals with prediabetes: a randomised placebo-controlled trial.

Nahon KJ, Doornink F, Straat ME, Botani K, Martinez-Tellez B, Abreu-Vieira G, van Klinken JB, Voortman GJ, Friesema ECH, Ruiz JR, van Velden FHP, de Geus-Oei LF, Smit F, Pereira Arias-Bouda LM, Berbée JFP, Jazet IM, Boon MR, Rensen PCN.

Diabetologia. 2018 Nov;61(11):2386-2397. doi: 10.1007/s00125-018-4716-x. Epub 2018 Aug 25.

24.

IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.

Kuipers EN, van Dam AD, Ballak DB, de Wit EA, Dinarello CA, Stienstra R, van Diepen JA, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Aug 2;19(8). pii: E2264. doi: 10.3390/ijms19082264.

25.

Gene Expression of Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight.

Nahon KJ, Kantae V, den Haan R, Hanssen MJW, Harms AC, van der Stelt M, Hankemeier T, Jazet IM, van Marken Lichtenbelt WD, Rensen PCN, Boon MR.

Obesity (Silver Spring). 2018 Aug;26(8):1332-1337. doi: 10.1002/oby.22245. Epub 2018 Aug 1.

PMID:
30070030
26.

Role of Human Brown Fat in Obesity, Metabolism and Cardiovascular Disease: Strategies to Turn Up the Heat.

Ruiz JR, Martinez-Tellez B, Sanchez-Delgado G, Osuna-Prieto FJ, Rensen PCN, Boon MR.

Prog Cardiovasc Dis. 2018 Jul - Aug;61(2):232-245. doi: 10.1016/j.pcad.2018.07.002. Epub 2018 Jul 4. Review.

PMID:
29981351
27.

Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.

Held NM, Kuipers EN, van Weeghel M, van Klinken JB, Denis SW, Lombès M, Wanders RJ, Vaz FM, Rensen PCN, Verhoeven AJ, Boon MR, Houtkooper RH.

Sci Rep. 2018 Jun 22;8(1):9562. doi: 10.1038/s41598-018-27875-3.

28.

Quercetin Lowers Plasma Triglycerides Accompanied by White Adipose Tissue Browning in Diet-Induced Obese Mice.

Kuipers EN, Dam ADV, Held NM, Mol IM, Houtkooper RH, Rensen PCN, Boon MR.

Int J Mol Sci. 2018 Jun 16;19(6). pii: E1786. doi: 10.3390/ijms19061786.

29.

Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.

van Loon NM, Ottenhoff R, Kooijman S, Moeton M, Scheij S, Roscam Abbing RLP, Gijbels MJJ, Levels JHM, Sorrentino V, Berbée JFP, Rensen PCN, Zelcer N.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1785-1795. doi: 10.1161/ATVBAHA.118.311168.

30.

Metabolic liver inflammation in obesity does not robustly decrease hepatic and circulating CETP.

Blauw LL, Li Z, Rensen SS, Greve JWM, Verhoeven A, Derks RJ, Giera M, Wang Y, Rensen PCN.

Atherosclerosis. 2018 Aug;275:149-155. doi: 10.1016/j.atherosclerosis.2018.06.004. Epub 2018 Jun 7.

31.

In vivo and in silico dynamics of the development of Metabolic Syndrome.

Rozendaal YJW, Wang Y, Paalvast Y, Tambyrajah LL, Li Z, Willems van Dijk K, Rensen PCN, Kuivenhoven JA, Groen AK, Hilbers PAJ, van Riel NAW.

PLoS Comput Biol. 2018 Jun 7;14(6):e1006145. doi: 10.1371/journal.pcbi.1006145. eCollection 2018 Jun.

32.

The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults.

Martinez-Tellez B, Nahon KJ, Sanchez-Delgado G, Abreu-Vieira G, Llamas-Elvira JM, van Velden FHP, Pereira Arias-Bouda LM, Rensen PCN, Boon MR, Ruiz JR.

Sci Rep. 2018 Jun 4;8(1):8567. doi: 10.1038/s41598-018-26878-4.

33.

MicroRNA-132 controls water homeostasis through regulating MECP2-mediated vasopressin synthesis.

Bijkerk R, Trimpert C, van Solingen C, de Bruin RG, Florijn BW, Kooijman S, van den Berg R, van der Veer EP, Bredewold EOW, Rensen PCN, Rabelink TJ, Humphreys BD, Deen PMT, van Zonneveld AJ.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1129-F1138. doi: 10.1152/ajprenal.00087.2018. Epub 2018 May 30.

PMID:
29846108
34.

Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet.

Tahapary DL, de Ruiter K, Kurniawan F, Djuardi Y, Wang Y, Nurdin SME, Iskandar E, Minggu D, Yunir E, Guigas B, Supali T, Rensen PCN, Sartono E, Soewondo P, Harbuwono DS, Smit JWA, Yazdanbakhsh M.

Sci Rep. 2018 May 25;8(1):8149. doi: 10.1038/s41598-018-25092-6.

35.

CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease.

Blauw LL, Li-Gao R, Noordam R, de Mutsert R, Trompet S, Berbée JFP, Wang Y, van Klinken JB, Christen T, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Rensen PCN, Willems van Dijk K.

Circ Genom Precis Med. 2018 May;11(5):e002034. doi: 10.1161/CIRCGEN.117.002034.

PMID:
29728394
36.

A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening.

van den Berg R, Kooijman S, Noordam R, Ramkisoensing A, Abreu-Vieira G, Tambyrajah LL, Dijk W, Ruppert P, Mol IM, Kramar B, Caputo R, Puig LS, de Ruiter EM, Kroon J, Hoekstra M, van der Sluis RJ, Meijer OC, Willems van Dijk K, van Kerkhof LWM, Christodoulides C, Karpe F, Gerhart-Hines Z, Kersten S, Meijer JH, Coomans CP, van Heemst D, Biermasz NR, Rensen PCN.

Cell Rep. 2018 Mar 27;22(13):3521-3533. doi: 10.1016/j.celrep.2018.03.004.

37.

Regulation of Adipose Tissue Metabolism by the Endocannabinoid System.

van Eenige R, van der Stelt M, Rensen PCN, Kooijman S.

Trends Endocrinol Metab. 2018 May;29(5):326-337. doi: 10.1016/j.tem.2018.03.001. Epub 2018 Mar 24. Review.

PMID:
29588112
38.

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

van der Tuin SJL, Li Z, Berbée JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y.

J Am Heart Assoc. 2018 Mar 10;7(6). pii: e008105. doi: 10.1161/JAHA.117.008105.

39.

Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes.

van Eyk HJ, van Schinkel LD, Kantae V, Dronkers CEA, Westenberg JJM, de Roos A, Lamb HJ, Jukema JW, Harms AC, Hankemeier T, van der Stelt M, Jazet IM, Rensen PCN, Smit JWA.

Nutr Diabetes. 2018 Jan 17;8(1):6. doi: 10.1038/s41387-017-0016-7.

40.

The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat.

Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M.

EMBO Mol Med. 2018 Mar;10(3). pii: e8047. doi: 10.15252/emmm.201708047.

41.

Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose.

Li-Gao R, de Mutsert R, Rensen PCN, van Klinken JB, Prehn C, Adamski J, van Hylckama Vlieg A, den Heijer M, le Cessie S, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO.

Metabolomics. 2018;14(1):13. doi: 10.1007/s11306-017-1307-7. Epub 2017 Dec 12.

42.

Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice.

Eggink HM, Tambyrajah LL, van den Berg R, Mol IM, van den Heuvel JK, Koehorst M, Groen AK, Boelen A, Kalsbeek A, Romijn JA, Rensen PCN, Kooijman S, Soeters MR.

J Endocrinol. 2018 Feb;236(2):85-97. doi: 10.1530/JOE-17-0503. Epub 2017 Dec 12.

PMID:
29233934
43.

Short-term cooling increases serum angiopoietin-like 4 levels in healthy lean men.

Nahon KJ, Hoeke G, Bakker LEH, Jazet IM, Berbée JFP, Kersten S, Rensen PCN, Boon MR.

J Clin Lipidol. 2018 Jan - Feb;12(1):56-61. doi: 10.1016/j.jacl.2017.10.016. Epub 2017 Nov 1.

PMID:
29191670
44.

Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.

Christen T, Trompet S, Noordam R, Blauw LL, Gast KB, Rensen PCN, Willems van Dijk K, Rosendaal FR, de Mutsert R, Jukema JW; NEO study.

J Clin Lipidol. 2018 Jan - Feb;12(1):137-144.e1. doi: 10.1016/j.jacl.2017.10.023. Epub 2017 Nov 2.

PMID:
29174438
45.

A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults.

Martinez-Tellez B, Sanchez-Delgado G, Garcia-Rivero Y, Alcantara JMA, Martinez-Avila WD, Muñoz-Hernandez MV, Olza J, Boon MR, Rensen PCN, Llamas-Elvira JM, Ruiz JR.

Front Physiol. 2017 Nov 2;8:863. doi: 10.3389/fphys.2017.00863. eCollection 2017.

46.

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis.

Hoeke G, Wang Y, van Dam AD, Mol IM, Gart E, Klop HG, van den Berg SM, Pieterman EH, Princen HMG, Groen AK, Rensen PCN, Berbée JFP, Boon MR.

Atherosclerosis. 2017 Dec;267:116-126. doi: 10.1016/j.atherosclerosis.2017.10.030. Epub 2017 Oct 26.

PMID:
29121499
47.

Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit.

Li Z, Yi CX, Katiraei S, Kooijman S, Zhou E, Chung CK, Gao Y, van den Heuvel JK, Meijer OC, Berbée JFP, Heijink M, Giera M, Willems van Dijk K, Groen AK, Rensen PCN, Wang Y.

Gut. 2018 Jul;67(7):1269-1279. doi: 10.1136/gutjnl-2017-314050. Epub 2017 Nov 3.

PMID:
29101261
48.

Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.

Paalvast Y, Gerding A, Wang Y, Bloks VW, van Dijk TH, Havinga R, Willems van Dijk K, Rensen PCN, Bakker BM, Kuivenhoven JA, Groen AK.

Physiol Rep. 2017 Oct;5(19). pii: e13376. doi: 10.14814/phy2.13376. Epub 2017 Oct 16. Erratum in: Physiol Rep. 2018 Mar;6(6):e13608.

49.

Lower critical temperature and cold-induced thermogenesis of lean and overweight humans are inversely related to body mass and basal metabolic rate.

Nahon KJ, Boon MR, Doornink F, Jazet IM, Rensen PCN, Abreu-Vieira G.

J Therm Biol. 2017 Oct;69:238-248. doi: 10.1016/j.jtherbio.2017.08.006. Epub 2017 Aug 12.

PMID:
29037389
50.

Metabolic imaging of fatty kidney in diabesity: validation and dietary intervention.

Jonker JT, de Heer P, Engelse MA, van Rossenberg EH, Klessens CQF, Baelde HJ, Bajema IM, Koopmans SJ, Coelho PG, Streefland TCM, Webb AG, Dekkers IA, Rabelink TJ, Rensen PCN, Lamb HJ, de Vries APJ.

Nephrol Dial Transplant. 2018 Feb 1;33(2):224-230. doi: 10.1093/ndt/gfx243.

PMID:
28992141

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