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Items: 9


Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3.

Nardi I, Reno T, Yun X, Sztain T, Wang J, Dai H, Zheng L, Shen B, Kim J, Raz D.

Int J Cancer. 2018 Nov 15;143(10):2470-2478. doi: 10.1002/ijc.31756. Epub 2018 Sep 19.


Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.

Zhang K, Wang J, Tong TR, Wu X, Nelson R, Yuan YC, Reno T, Liu Z, Yun X, Kim JY, Salgia R, Raz DJ.

Int J Cancer. 2017 Aug 15;141(4):766-777. doi: 10.1002/ijc.30769. Epub 2017 May 31.


The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer.

Reno TA, Tong SW, Wu J, Fidler JM, Nelson R, Kim JY, Raz DJ.

BMC Cancer. 2016 Jul 11;16:439. doi: 10.1186/s12885-016-2487-7.


Triptolide Inhibits Lung Cancer Cell Migration, Invasion, and Metastasis.

Reno TA, Kim JY, Raz DJ.

Ann Thorac Surg. 2015 Nov;100(5):1817-24; discussion 1824-5. doi: 10.1016/j.athoracsur.2015.05.074. Epub 2015 Aug 20.


Dynamic phosphorylation of tyrosine 665 in pseudopodium-enriched atypical kinase 1 (PEAK1) is essential for the regulation of cell migration and focal adhesion turnover.

Bristow JM, Reno TA, Jo M, Gonias SL, Klemke RL.

J Biol Chem. 2013 Jan 4;288(1):123-31. doi: 10.1074/jbc.M112.410910. Epub 2012 Oct 26.


KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.

Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL.

Cancer Res. 2012 May 15;72(10):2554-64. doi: 10.1158/0008-5472.CAN-11-3552.


Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells.

Wang Y, Yang F, Gritsenko MA, Wang Y, Clauss T, Liu T, Shen Y, Monroe ME, Lopez-Ferrer D, Reno T, Moore RJ, Klemke RL, Camp DG 2nd, Smith RD.

Proteomics. 2011 May;11(10):2019-26. doi: 10.1002/pmic.201000722. Epub 2011 Apr 18.


Selection of T cell receptor expression mutants through the functionally linked Ly-6A.

Sugiyama E, Cantagrel A, Reno T, Stafford-Brady F, Yeh ET, Bonventre JV.

Cell Immunol. 1990 Oct 15;130(2):271-80.


Defects in signal transduction caused by a T cell receptor beta chain substitution.

Reno TA, Ley S, Sugiyama E, Cantagrel A, Blumberg R, Bonventre J, Terhorst C, Yeh ET.

Eur J Immunol. 1990 Jul;20(7):1417-22.


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