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Items: 9

1.

A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm.

Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng XH, Baldi E, Publicover SJ, Benjamin Kaupp U, Strünker T.

Br J Pharmacol. 2018 Aug;175(15):3144-3161. doi: 10.1111/bph.14355. Epub 2018 Jun 29.

PMID:
29723408
2.

Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm.

Brenker C, Schiffer C, Wagner IV, Tüttelmann F, Röpke A, Rennhack A, Kaupp UB, Strünker T.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E344-E346. doi: 10.1073/pnas.1717929115. Epub 2018 Jan 5. No abstract available.

3.

Photocontrol of the Hv1 Proton Channel.

Rennhack A, Grahn E, Kaupp UB, Berger TK.

ACS Chem Biol. 2017 Dec 15;12(12):2952-2957. doi: 10.1021/acschembio.7b00523. Epub 2017 Nov 7.

PMID:
29024582
4.

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D.

J Biol Chem. 2017 Apr 14;292(15):6177-6189. doi: 10.1074/jbc.M116.762831. Epub 2017 Mar 3.

5.

Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus.

Royeck M, Kelly T, Opitz T, Otte DM, Rennhack A, Woitecki A, Pitsch J, Becker A, Schoch S, Kaupp UB, Yaari Y, Zimmer A, Beck H.

J Neurosci. 2015 Nov 18;35(46):15240-53. doi: 10.1523/JNEUROSCI.0493-15.2015.

6.

Sperm navigation along helical paths in 3D chemoattractant landscapes.

Jikeli JF, Alvarez L, Friedrich BM, Wilson LG, Pascal R, Colin R, Pichlo M, Rennhack A, Brenker C, Kaupp UB.

Nat Commun. 2015 Aug 17;6:7985. doi: 10.1038/ncomms8985.

7.

Synthesis of a potent photoreactive acidic γ-secretase modulator for target identification in cells.

Rennhack A, Jumpertz T, Ness J, Baches S, Pietrzik CU, Weggen S, Bulic B.

Bioorg Med Chem. 2012 Nov 1;20(21):6523-32. doi: 10.1016/j.bmc.2012.08.034. Epub 2012 Aug 31.

PMID:
23000293
8.

Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer's Disease.

Bulic B, Ness J, Hahn S, Rennhack A, Jumpertz T, Weggen S.

Curr Neuropharmacol. 2011 Dec;9(4):598-622. doi: 10.2174/157015911798376352.

9.

Presenilin is the molecular target of acidic γ-secretase modulators in living cells.

Jumpertz T, Rennhack A, Ness J, Baches S, Pietrzik CU, Bulic B, Weggen S.

PLoS One. 2012;7(1):e30484. doi: 10.1371/journal.pone.0030484. Epub 2012 Jan 6.

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