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Items: 25


High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy.

Jordi J, Guggiana-Nilo D, Bolton AD, Prabha S, Ballotti K, Herrera K, Rennekamp AJ, Peterson RT, Lutz TA, Engert F.

Sci Adv. 2018 Oct 31;4(10):eaav1966. doi: 10.1126/sciadv.aav1966. eCollection 2018 Oct.


Toward a Choate View of Fate.

Rennekamp AJ.

Cell. 2018 Jun 28;174(1):1-3. doi: 10.1016/j.cell.2018.06.024. No abstract available.


Modulation of Threat Response in Larval Zebrafish.

Rennekamp AJ.

Methods Mol Biol. 2018;1787:147-159. doi: 10.1007/978-1-4939-7847-2_11.


The Ferrous Awakens.

Rennekamp AJ.

Cell. 2017 Nov 30;171(6):1225-1227. doi: 10.1016/j.cell.2017.11.029.


Chemical Screening in Zebrafish.

Brady CA, Rennekamp AJ, Peterson RT.

Methods Mol Biol. 2016;1451:3-16. doi: 10.1007/978-1-4939-3771-4_1.


σ1 receptor ligands control a switch between passive and active threat responses.

Rennekamp AJ, Huang XP, Wang Y, Patel S, Lorello PJ, Cade L, Gonzales AP, Yeh JR, Caldarone BJ, Roth BL, Kokel D, Peterson RT.

Nat Chem Biol. 2016 Jul;12(7):552-8. doi: 10.1038/nchembio.2089. Epub 2016 May 30.


Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.

Bruni G, Rennekamp AJ, Velenich A, McCarroll M, Gendelev L, Fertsch E, Taylor J, Lakhani P, Lensen D, Evron T, Lorello PJ, Huang XP, Kolczewski S, Carey G, Caldarone BJ, Prinssen E, Roth BL, Keiser MJ, Peterson RT, Kokel D.

Nat Chem Biol. 2016 Jul;12(7):559-66. doi: 10.1038/nchembio.2097. Epub 2016 May 30.


Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides.

Vardy E, Sassano MF, Rennekamp AJ, Kroeze WK, Mosier PD, Westkaemper RB, Stevens CW, Katritch V, Stevens RC, Peterson RT, Roth BL.

Chem Biol. 2015 Jun 18;22(6):764-75. doi: 10.1016/j.chembiol.2015.05.012.


15 years of zebrafish chemical screening.

Rennekamp AJ, Peterson RT.

Curr Opin Chem Biol. 2015 Feb;24:58-70. doi: 10.1016/j.cbpa.2014.10.025. Epub 2014 Nov 15.


From phenotype to mechanism after zebrafish small molecule screens.

Rennekamp AJ, Peterson RT.

Drug Discov Today Dis Models. 2013 Spring;10(1):e51-e55.


Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology.

Kokel D, Rennekamp AJ, Shah AH, Liebel U, Peterson RT.

Trends Biotechnol. 2012 Aug;30(8):421-5. doi: 10.1016/j.tibtech.2012.05.001. Epub 2012 May 29. Review.


Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion.

Simmons G, Bertram S, Glowacka I, Steffen I, Chaipan C, Agudelo J, Lu K, Rennekamp AJ, Hofmann H, Bates P, Pöhlmann S.

Virology. 2011 May 10;413(2):265-74. doi: 10.1016/j.virol.2011.02.020. Epub 2011 Mar 23.


Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNA-DNA hybrid molecule at OriLyt.

Rennekamp AJ, Lieberman PM.

J Virol. 2011 Mar;85(6):2837-50. doi: 10.1128/JVI.02175-10. Epub 2010 Dec 29.


Evidence for DNA hairpin recognition by Zta at the Epstein-Barr virus origin of lytic replication.

Rennekamp AJ, Wang P, Lieberman PM.

J Virol. 2010 Jul;84(14):7073-82. doi: 10.1128/JVI.02666-09. Epub 2010 May 5.


Topoisomerase I and RecQL1 function in Epstein-Barr virus lytic reactivation.

Wang P, Rennekamp AJ, Yuan Y, Lieberman PM.

J Virol. 2009 Aug;83(16):8090-8. doi: 10.1128/JVI.02379-08. Epub 2009 Jun 3.


Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication.

Wiedmer A, Wang P, Zhou J, Rennekamp AJ, Tiranti V, Zeviani M, Lieberman PM.

J Virol. 2008 May;82(9):4647-55. doi: 10.1128/JVI.02198-07. Epub 2008 Feb 27.


Chromatin profiling of Epstein-Barr virus latency control region.

Day L, Chau CM, Nebozhyn M, Rennekamp AJ, Showe M, Lieberman PM.

J Virol. 2007 Jun;81(12):6389-401. Epub 2007 Apr 4.


Proteolysis of SARS-associated coronavirus spike glycoprotein.

Simmons G, Rennekamp AJ, Bates P.

Adv Exp Med Biol. 2006;581:235-40. No abstract available.


Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors.

Hofmann H, Simmons G, Rennekamp AJ, Chaipan C, Gramberg T, Heck E, Geier M, Wegele A, Marzi A, Bates P, Pöhlmann S.

J Virol. 2006 Sep;80(17):8639-52.


Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.

Simmons G, Gosalia DN, Rennekamp AJ, Reeves JD, Diamond SL, Bates P.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11876-81. Epub 2005 Aug 4.


DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus.

Marzi A, Gramberg T, Simmons G, Möller P, Rennekamp AJ, Krumbiegel M, Geier M, Eisemann J, Turza N, Saunier B, Steinkasserer A, Becker S, Bates P, Hofmann H, Pöhlmann S.

J Virol. 2004 Nov;78(21):12090-5.


Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry.

Simmons G, Reeves JD, Rennekamp AJ, Amberg SM, Piefer AJ, Bates P.

Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4240-5. Epub 2004 Mar 9.


Identification of murine T-cell epitopes in Ebola virus nucleoprotein.

Simmons G, Lee A, Rennekamp AJ, Fan X, Bates P, Shen H.

Virology. 2004 Jan 5;318(1):224-30.


Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.

Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, Bates P.

J Virol. 2003 Dec;77(24):13433-8.

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