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Items: 24


Phosphorylated claudin-16 interacts with Trpv5 and regulates transcellular calcium transport in the kidney.

Hou J, Renigunta V, Nie M, Sunq A, Himmerkus N, Quintanova C, Bleich M, Renigunta A, Wolf MTF.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19176-19186. doi: 10.1073/pnas.1902042116. Epub 2019 Sep 5.


Biochemical and biophysical analyses of tight junction permeability made of claudin-16 and claudin-19 dimerization.

Gong Y, Renigunta V, Zhou Y, Sunq A, Wang J, Yang J, Renigunta A, Baker LA, Hou J.

Mol Biol Cell. 2015 Dec 1;26(24):4333-46. doi: 10.1091/mbc.E15-06-0422. Epub 2015 Oct 7.


Much more than a leak: structure and function of K₂p-channels.

Renigunta V, Schlichthörl G, Daut J.

Pflugers Arch. 2015 May;467(5):867-94. doi: 10.1007/s00424-015-1703-7. Epub 2015 Mar 21. Review.


The role of protein-protein interactions in the intracellular traffic of the potassium channels TASK-1 and TASK-3.

Kilisch M, Lytovchenko O, Schwappach B, Renigunta V, Daut J.

Pflugers Arch. 2015 May;467(5):1105-20. doi: 10.1007/s00424-014-1672-2. Epub 2015 Jan 7. Review.


Cooperative endocytosis of the endosomal SNARE protein syntaxin-8 and the potassium channel TASK-1.

Renigunta V, Fischer T, Zuzarte M, Kling S, Zou X, Siebert K, Limberg MM, Rinné S, Decher N, Schlichthörl G, Daut J.

Mol Biol Cell. 2014 Jun 15;25(12):1877-91. doi: 10.1091/mbc.E13-10-0592. Epub 2014 Apr 17.


Breaking the silence: functional expression of the two-pore-domain potassium channel THIK-2.

Renigunta V, Zou X, Kling S, Schlichthörl G, Daut J.

Pflugers Arch. 2014 Sep;466(9):1735-45. doi: 10.1007/s00424-013-1404-z. Epub 2013 Dec 3.


A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels.

Rinné S, Renigunta V, Schlichthörl G, Zuzarte M, Bittner S, Meuth SG, Decher N, Daut J, Preisig-Müller R.

Pflugers Arch. 2014 Aug;466(8):1559-70. doi: 10.1007/s00424-013-1384-z. Epub 2013 Nov 7.


A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.

Anders C, Higuchi Y, Koschinsky K, Bartel M, Schumacher B, Thiel P, Nitta H, Preisig-Müller R, Schlichthörl G, Renigunta V, Ohkanda J, Daut J, Kato N, Ottmann C.

Chem Biol. 2013 Apr 18;20(4):583-93. doi: 10.1016/j.chembiol.2013.03.015.


The inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C.

Schiekel J, Lindner M, Hetzel A, Wemhöner K, Renigunta V, Schlichthörl G, Decher N, Oliver D, Daut J.

Cardiovasc Res. 2013 Jan 1;97(1):97-105. doi: 10.1093/cvr/cvs285. Epub 2012 Sep 12.


Claudin-14 regulates renal Ca⁺⁺ transport in response to CaSR signalling via a novel microRNA pathway.

Gong Y, Renigunta V, Himmerkus N, Zhang J, Renigunta A, Bleich M, Hou J.

EMBO J. 2012 Apr 18;31(8):1999-2012. doi: 10.1038/emboj.2012.49. Epub 2012 Feb 28.


The glycolytic enzymes glyceraldehyde 3-phosphate dehydrogenase and enolase interact with the renal epithelial K+ channel ROMK2 and regulate its function.

Renigunta A, Mutig K, Rottermann K, Schlichthörl G, Preisig-Müller R, Daut J, Waldegger S, Renigunta V.

Cell Physiol Biochem. 2011;28(4):663-72. doi: 10.1159/000335761. Epub 2011 Dec 14.


A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore.

Streit AK, Netter MF, Kempf F, Walecki M, Rinné S, Bollepalli MK, Preisig-Müller R, Renigunta V, Daut J, Baukrowitz T, Sansom MS, Stansfeld PJ, Decher N.

J Biol Chem. 2011 Apr 22;286(16):13977-84. doi: 10.1074/jbc.M111.227884. Epub 2011 Mar 1.


Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function.

Renigunta A, Renigunta V, Saritas T, Decher N, Mutig K, Waldegger S.

J Biol Chem. 2011 Jan 21;286(3):2224-35. doi: 10.1074/jbc.M110.149880. Epub 2010 Nov 16.


RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels.

Decher N, Streit AK, Rapedius M, Netter MF, Marzian S, Ehling P, Schlichthörl G, Craan T, Renigunta V, Köhler A, Dodel RC, Navarro-Polanco RA, Preisig-Müller R, Klebe G, Budde T, Baukrowitz T, Daut J.

EMBO J. 2010 Jul 7;29(13):2101-13. doi: 10.1038/emboj.2010.88. Epub 2010 May 11.


Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins.

Zuzarte M, Heusser K, Renigunta V, Schlichthörl G, Rinné S, Wischmeyer E, Daut J, Schwappach B, Preisig-Müller R.

J Physiol. 2009 Mar 1;587(Pt 5):929-52. doi: 10.1113/jphysiol.2008.164756. Epub 2009 Jan 12.


Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.

Mederos Y Schnitzler M, Rinné S, Skrobek L, Renigunta V, Schlichthörl G, Derst C, Gudermann T, Daut J, Preisig-Müller R.

J Biol Chem. 2009 Feb 13;284(7):4695-704. doi: 10.1074/jbc.M808786200. Epub 2008 Dec 11.


Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.

Decher N, Gonzalez T, Streit AK, Sachse FB, Renigunta V, Soom M, Heinemann SH, Daut J, Sanguinetti MC.

EMBO J. 2008 Dec 3;27(23):3164-74. doi: 10.1038/emboj.2008.231. Epub 2008 Nov 6.


Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.

Decher N, Renigunta V, Zuzarte M, Soom M, Heinemann SH, Timothy KW, Keating MT, Daut J, Sanguinetti MC, Splawski I.

Cardiovasc Res. 2007 Sep 1;75(4):748-57. Epub 2007 May 10.


Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages.

del Rey A, Renigunta V, Dalpke AH, Leipziger J, Matos JE, Robaye B, Zuzarte M, Kavelaars A, Hanley PJ.

J Biol Chem. 2006 Nov 17;281(46):35147-55. Epub 2006 Sep 15.


The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1.

Renigunta V, Yuan H, Zuzarte M, Rinné S, Koch A, Wischmeyer E, Schlichthörl G, Gao Y, Karschin A, Jacob R, Schwappach B, Daut J, Preisig-Müller R.

Traffic. 2006 Feb;7(2):168-81.


"Host tissue damage" signal ATP promotes non-directional migration and negatively regulates toll-like receptor signaling in human monocytes.

Kaufmann A, Musset B, Limberg SH, Renigunta V, Sus R, Dalpke AH, Heeg KM, Robaye B, Hanley PJ.

J Biol Chem. 2005 Sep 16;280(37):32459-67. Epub 2005 Jul 19.


Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels.

Decher N, Kumar P, Gonzalez T, Renigunta V, Sanguinetti MC.

Mol Pharmacol. 2005 Oct;68(4):995-1005. Epub 2005 Jul 15.


Extracellular ATP induces oscillations of intracellular Ca2+ and membrane potential and promotes transcription of IL-6 in macrophages.

Hanley PJ, Musset B, Renigunta V, Limberg SH, Dalpke AH, Sus R, Heeg KM, Preisig-Müller R, Daut J.

Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9479-84. Epub 2004 Jun 11.


Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3.

Rajan S, Preisig-Müller R, Wischmeyer E, Nehring R, Hanley PJ, Renigunta V, Musset B, Schlichthörl G, Derst C, Karschin A, Daut J.

J Physiol. 2002 Nov 15;545(1):13-26.

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