Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64

1.

A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.

Gay M, Evrard C, Descamps F, Carato P, Renault N, Coevoet M, Eddarkaoui S, Baud C, Larchanché PE, Buée L, El Bakali J, Vingtdeux V, Sergeant N, Melnyk P.

Eur J Med Chem. 2018 Nov 5;159:104-125. doi: 10.1016/j.ejmech.2018.08.092. Epub 2018 Sep 22.

PMID:
30268822
2.

Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure.

Boulahjar R, Rincon Arias A, Bolteau R, Renault N, Coevoet M, Barczyk A, Duroux R, Yous S, Melnyk P, Agouridas L.

Bioorg Med Chem. 2018 Jul 23;26(12):3296-3307. doi: 10.1016/j.bmc.2018.04.057. Epub 2018 Apr 30.

PMID:
29753566
3.

Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P.

Cancers (Basel). 2018 May 8;10(5). pii: E140. doi: 10.3390/cancers10050140.

4.

New phenylaniline derivatives as modulators of amyloid protein precursor metabolism.

Gay M, Carato P, Coevoet M, Renault N, Larchanché PE, Barczyk A, Yous S, Buée L, Sergeant N, Melnyk P.

Bioorg Med Chem. 2018 May 1;26(8):2151-2164. doi: 10.1016/j.bmc.2018.03.016. Epub 2018 Mar 12.

PMID:
29559198
5.

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors.

El Harane N, Kervadec A, Bellamy V, Pidial L, Neametalla HJ, Perier MC, Lima Correa B, Thiébault L, Cagnard N, Duché A, Brunaud C, Lemitre M, Gauthier J, Bourdillon AT, Renault MP, Hovhannisyan Y, Paiva S, Colas AR, Agbulut O, Hagège A, Silvestre JS, Menasché P, Renault NKE.

Eur Heart J. 2018 May 21;39(20):1835-1847. doi: 10.1093/eurheartj/ehy012.

PMID:
29420830
6.

Antagonists of the adenosine A2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity.

Duroux R, Agouridas L, Renault N, El Bakali J, Furman C, Melnyk P, Yous S.

Eur J Med Chem. 2018 Jan 20;144:151-163. doi: 10.1016/j.ejmech.2017.12.007. Epub 2017 Dec 5.

PMID:
29268131
7.

[An innovative position during skin-to-skin contact in neonatology].

Buil A, Renault N, Boulonnois É, Apter G, Devouche E.

Soins Pediatr Pueric. 2017 Nov - Dec;38(299):36-39. doi: 10.1016/j.spp.2017.09.008. French.

PMID:
29162258
8.

Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50.

Clement N, Renault N, Guillaume JL, Cecon E, Journé AS, Laurent X, Tadagaki K, Cogé F, Gohier A, Delagrange P, Chavatte P, Jockers R.

Br J Pharmacol. 2017 Sep 12. doi: 10.1111/bph.14029. [Epub ahead of print]

9.

Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor.

Duroux R, Renault N, Cuelho JE, Agouridas L, Blum D, Lopes LV, Melnyk P, Yous S.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):850-864. doi: 10.1080/14756366.2017.1334648.

PMID:
28661196
10.

Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.

Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N.

J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30.

PMID:
27538123
11.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.

Ngkelo A, Richart A, Kirk JA, Bonnin P, Vilar J, Lemitre M, Marck P, Branchereau M, Le Gall S, Renault N, Guerin C, Ranek MJ, Kervadec A, Danelli L, Gautier G, Blank U, Launay P, Camerer E, Bruneval P, Menasche P, Heymes C, Luche E, Casteilla L, Cousin B, Rodewald HR, Kass DA, Silvestre JS.

J Exp Med. 2016 Jun 27;213(7):1353-74. doi: 10.1084/jem.20160081.

12.

Update on melatonin receptors: IUPHAR Review 20.

Jockers R, Delagrange P, Dubocovich ML, Markus RP, Renault N, Tosini G, Cecon E, Zlotos DP.

Br J Pharmacol. 2016 Sep;173(18):2702-25. doi: 10.1111/bph.13536. Epub 2016 Aug 8. Review.

13.

Design, synthesis and biological evaluation of potent FAAH inhibitors.

Tuo W, Leleu-Chavain N, Barczyk A, Renault N, Lemaire L, Chavatte P, Millet R.

Bioorg Med Chem Lett. 2016 Jun 1;26(11):2701-5. doi: 10.1016/j.bmcl.2016.04.004. Epub 2016 Apr 23.

PMID:
27117424
14.

Cardiovascular progenitor-derived extracellular vesicles recapitulate the beneficial effects of their parent cells in the treatment of chronic heart failure.

Kervadec A, Bellamy V, El Harane N, Arakélian L, Vanneaux V, Cacciapuoti I, Nemetalla H, Périer MC, Toeg HD, Richart A, Lemitre M, Yin M, Loyer X, Larghero J, Hagège A, Ruel M, Boulanger CM, Silvestre JS, Menasché P, Renault NK.

J Heart Lung Transplant. 2016 Jun;35(6):795-807. doi: 10.1016/j.healun.2016.01.013. Epub 2016 Jan 19.

PMID:
27041495
15.

Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents.

Driowya M, Leclercq J, Verones V, Barczyk A, Lecoeur M, Renault N, Flouquet N, Ghinet A, Berthelot P, Lebegue N.

Eur J Med Chem. 2016 Jun 10;115:393-405. doi: 10.1016/j.ejmech.2016.03.056. Epub 2016 Mar 22.

PMID:
27031215
16.

Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines.

Moas-Héloire V, Renault N, Batalha V, Arias AR, Marchivie M, Yous S, Deguine N, Buée L, Chavatte P, Blum D, Lopes L, Melnyk P, Agouridas L.

Eur J Med Chem. 2015 Dec 1;106:15-25. doi: 10.1016/j.ejmech.2015.10.030. Epub 2015 Oct 19.

PMID:
26513641
17.

Impact of gender on use of revascularization in acute coronary syndromes: the national observational study of diagnostic and interventional cardiac catheterization (ONACI).

Isorni MA, Blanchard D, Teixeira N, le Breton H, Renault N, Gilard M, Lefèvre T, Mulak G, Danchin N, Spaulding C, Puymirat E.

Catheter Cardiovasc Interv. 2015 Aug;86(2):E58-65. doi: 10.1002/ccd.25921. Epub 2015 Mar 24.

PMID:
25810163
18.

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

El Bakali J, Muccioli GG, Body-Malapel M, Djouina M, Klupsch F, Ghinet A, Barczyk A, Renault N, Chavatte P, Desreumaux P, Lambert DM, Millet R.

ACS Med Chem Lett. 2014 Dec 4;6(2):198-203. doi: 10.1021/ml500439x. eCollection 2015 Feb 12.

19.

Relationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulations.

Laurent X, Renault N, Farce A, Chavatte P, Hénon E.

PLoS Comput Biol. 2014 Nov 6;10(11):e1003902. doi: 10.1371/journal.pcbi.1003902. eCollection 2014 Nov.

20.

Switching invariant natural killer T (iNKT) cell response from anticancerous to anti-inflammatory effect: molecular bases.

Laurent X, Bertin B, Renault N, Farce A, Speca S, Milhomme O, Millet R, Desreumaux P, Hénon E, Chavatte P.

J Med Chem. 2014 Jul 10;57(13):5489-508. doi: 10.1021/jm4010863. Epub 2014 Feb 12. Review.

PMID:
24428717
21.

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

Tourteau A, Andrzejak V, Body-Malapel M, Lemaire L, Lemoine A, Mansouri R, Djouina M, Renault N, El Bakali J, Desreumaux P, Muccioli GG, Lambert DM, Chavatte P, Rigo B, Leleu-Chavain N, Millet R.

Bioorg Med Chem. 2013 Sep 1;21(17):5383-94. doi: 10.1016/j.bmc.2013.06.010. Epub 2013 Jun 15.

PMID:
23849204
22.

Minireview: Toward the establishment of a link between melatonin and glucose homeostasis: association of melatonin MT2 receptor variants with type 2 diabetes.

Karamitri A, Renault N, Clement N, Guillaume JL, Jockers R.

Mol Endocrinol. 2013 Aug;27(8):1217-33. doi: 10.1210/me.2013-1101. Epub 2013 Jun 24. Review.

23.

Human X-chromosome inactivation pattern distributions fit a model of genetically influenced choice better than models of completely random choice.

Renault NK, Pritchett SM, Howell RE, Greer WL, Sapienza C, Ørstavik KH, Hamilton DC.

Eur J Hum Genet. 2013 Dec;21(12):1396-402. doi: 10.1038/ejhg.2013.84. Epub 2013 May 8.

24.

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.

Renault N, Laurent X, Farce A, El Bakali J, Mansouri R, Gervois P, Millet R, Desreumaux P, Furman C, Chavatte P.

Chem Biol Drug Des. 2013 Apr;81(4):442-54. doi: 10.1111/cbdd.12095.

PMID:
23217060
25.

Novel splice-site mutation in ATP8B1 results in atypical progressive familial intrahepatic cholestasis type 1.

Copeland E, Renault N, Renault M, Dyack S, Bulman DE, Bedard K, Otley A, Magee F, Acott P, Greer WL.

J Gastroenterol Hepatol. 2013 Mar;28(3):560-4. doi: 10.1111/j.1440-1746.2012.07290.x.

PMID:
23033845
26.

Mixed metallic Ba(Co,Fe)X(0.2)O(3-δ) (X = F, Cl) hexagonal perovskites: drastic effect of Fe-incorporation on structural and electronic features.

Iorgulescu M, Roussel P, Tancret N, Renault N, Porcher F, André G, Kabbour H, Mentré O.

Inorg Chem. 2012 Jul 16;51(14):7598-608. doi: 10.1021/ic3004068. Epub 2012 Jun 27.

PMID:
22738157
27.

Prediction of tolerance in children with IgE mediated cow's milk allergy by microarray profiling and chemometric approach.

Wulfert F, Sanyasi G, Tongen L, Watanabe LA, Wang X, Renault NK, Falcone FH, Jacob CM, Alcocer MJ.

J Immunol Methods. 2012 Aug 31;382(1-2):48-57. doi: 10.1016/j.jim.2012.05.004. Epub 2012 May 8.

28.

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

Pirat C, Farce A, Lebègue N, Renault N, Furman C, Millet R, Yous S, Speca S, Berthelot P, Desreumaux P, Chavatte P.

J Med Chem. 2012 May 10;55(9):4027-61. doi: 10.1021/jm101360s. Epub 2012 Feb 27. Review. No abstract available.

PMID:
22260081
29.

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

Lino Cardenas CL, Renault N, Farce A, Cauffiez C, Allorge D, Lo-Guidice JM, Lhermitte M, Chavatte P, Broly F, Chevalier D.

Gene. 2011 Nov 1;487(1):10-20. doi: 10.1016/j.gene.2011.07.015. Epub 2011 Jul 27.

PMID:
21820496
30.

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis.

Andrzejak V, Muccioli GG, Body-Malapel M, El Bakali J, Djouina M, Renault N, Chavatte P, Desreumaux P, Lambert DM, Millet R.

Bioorg Med Chem. 2011 Jun 15;19(12):3777-86. doi: 10.1016/j.bmc.2011.04.057. Epub 2011 May 6.

PMID:
21612933
31.

Familial skewed X-chromosome inactivation linked to a component of the cohesin complex, SA2.

Renault NK, Renault MP, Copeland E, Howell RE, Greer WL.

J Hum Genet. 2011 May;56(5):390-7. doi: 10.1038/jhg.2011.25. Epub 2011 Mar 17.

PMID:
21412246
32.

A nuclear export signal within the structural Gag protein is required for prototype foamy virus replication.

Renault N, Tobaly-Tapiero J, Paris J, Giron ML, Coiffic A, Roingeard P, Saïb A.

Retrovirology. 2011 Jan 21;8(1):6. doi: 10.1186/1742-4690-8-6.

33.

Two distinct variants of simian foamy virus in naturally infected mandrills (Mandrillus sphinx) and cross-species transmission to humans.

Mouinga-Ondémé A, Betsem E, Caron M, Makuwa M, Sallé B, Renault N, Saib A, Telfer P, Marx P, Gessain A, Kazanji M.

Retrovirology. 2010 Dec 14;7:105. doi: 10.1186/1742-4690-7-105.

34.

Qualitative assessment of the emotional and behavioural responses of haemophilia A carriers to negative experiences in their medical care.

Renault NK, Howell RE, Robinson KS, Greer WL.

Haemophilia. 2011 Mar;17(2):237-45. doi: 10.1111/j.1365-2516.2010.02424.x. Epub 2010 Dec 1.

PMID:
21118331
35.

4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands: structural insights into the design of a novel inverse agonist series.

El Bakali J, Muccioli GG, Renault N, Pradal D, Body-Malapel M, Djouina M, Hamtiaux L, Andrzejak V, Desreumaux P, Chavatte P, Lambert DM, Millet R.

J Med Chem. 2010 Nov 25;53(22):7918-31. doi: 10.1021/jm100286k. Epub 2010 Oct 27.

PMID:
20979417
36.

Multiple protein extract microarray for profiling human food-specific immunoglobulins A, M, G and E.

Renault NK, Gaddipati SR, Wulfert F, Falcone FH, Mirotti L, Tighe PJ, Wright V, Alcocer MJ.

J Immunol Methods. 2011 Feb 1;364(1-2):21-32. doi: 10.1016/j.jim.2010.10.004. Epub 2010 Oct 23.

PMID:
20974146
37.

Novel structural insights for drug design of selective 5-HT(2C) inverse agonists from a ligand-biased receptor model.

Renault N, Gohier A, Chavatte P, Farce A.

Eur J Med Chem. 2010 Nov;45(11):5086-99. doi: 10.1016/j.ejmech.2010.08.018. Epub 2010 Aug 12.

PMID:
20880612
38.

Early reverse transcription is essential for productive foamy virus infection.

Zamborlini A, Renault N, Saïb A, Delelis O.

PLoS One. 2010 Jun 11;5(6):e11023. doi: 10.1371/journal.pone.0011023.

39.

Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome.

Bienaime F, Dragon-Durey MA, Regnier CH, Nilsson SC, Kwan WH, Blouin J, Jablonski M, Renault N, Rameix-Welti MA, Loirat C, Sautés-Fridman C, Villoutreix BO, Blom AM, Fremeaux-Bacchi V.

Kidney Int. 2010 Feb;77(4):339-49. doi: 10.1038/ki.2009.472. Epub 2009 Dec 16.

40.

The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.

Cogé F, Guenin SP, Fery I, Migaud M, Devavry S, Slugocki C, Legros C, Ouvry C, Cohen W, Renault N, Nosjean O, Malpaux B, Delagrange P, Boutin JA.

Br J Pharmacol. 2009 Nov;158(5):1248-62. doi: 10.1111/j.1476-5381.2009.00453.x. Epub 2009 Oct 8.

41.

Structural insight into PPARgamma ligands binding.

Farce A, Renault N, Chavatte P.

Curr Med Chem. 2009;16(14):1768-89. Review.

PMID:
19442144
42.

Impedimetric microanalysis system for deep vein thrombosis point-of-care testing.

Renault NJ, Korri-Youssoufi H, Kyselovik J, Auger V, Errachid A, Mills CA, Strohhöfer C, Ali Z.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:1856. doi: 10.1109/IEMBS.2008.4649544. No abstract available.

PMID:
19163047
43.

Genetic, molecular and functional analyses of complement factor I deficiency.

Nilsson SC, Trouw LA, Renault N, Miteva MA, Genel F, Zelazko M, Marquart H, Muller K, Sjöholm AG, Truedsson L, Villoutreix BO, Blom AM.

Eur J Immunol. 2009 Jan;39(1):310-23. doi: 10.1002/eji.200838702.

44.

Conductometric nitrate biosensor based on methyl viologen/Nafion/nitrate reductase interdigitated electrodes.

Xuejiang W, Dzyadevych SV, Chovelon JM, Renault NJ, Ling C, Siqing X, Jianfu Z.

Talanta. 2006 Apr 15;69(2):450-5. doi: 10.1016/j.talanta.2005.10.014. Epub 2005 Nov 28.

PMID:
18970588
45.

Conductometric tyrosinase biosensor for the detection of diuron, atrazine and its main metabolites.

Anh TM, Dzyadevych SV, Van MC, Renault NJ, Duc CN, Chovelon JM.

Talanta. 2004 May 28;63(2):365-70. doi: 10.1016/j.talanta.2003.11.008.

PMID:
18969441
46.

Molecular modelling of phthalates - PPARs interactions.

Kambia N, Renault N, Dilly S, Farce A, Dine T, Gressier B, Luyckx M, Brunet C, Chavatte P.

J Enzyme Inhib Med Chem. 2008 Oct;23(5):611-6. doi: 10.1080/14756360802205059 .

PMID:
18821250
47.

Characterisation of novel defective thiopurine S-methyltransferase allelic variants.

Garat A, Cauffiez C, Renault N, Lo-Guidice JM, Allorge D, Chevalier D, Houdret N, Chavatte P, Loriot MA, Gala JL, Broly F.

Biochem Pharmacol. 2008 Aug 1;76(3):404-15. doi: 10.1016/j.bcp.2008.05.009. Epub 2008 May 18.

PMID:
18602085
48.

Familial essential thrombocythemia with spontaneous megakaryocyte colony formation and acquired JAK2 mutations.

Higgs JR, Sadek I, Neumann PE, Ing VW, Renault NK, Berman JN, Greer WL.

Leukemia. 2008 Aug;22(8):1551-6. doi: 10.1038/leu.2008.115. Epub 2008 May 22.

PMID:
18496561
49.

Measuring plasma conductivity to detect sodium load in hemodialysis patients.

Mercadal L, Servais A, Venditto M, Renault N, Isnard-Bagnis C, Deray G, Petitclerc T.

Clin J Am Soc Nephrol. 2008 May;3(3):743-6. doi: 10.2215/CJN.03780907. Epub 2008 Mar 27.

50.

Homology modeling of MT1 and MT2 receptors.

Farce A, Chugunov AO, Logé C, Sabaouni A, Yous S, Dilly S, Renault N, Vergoten G, Efremov RG, Lesieur D, Chavatte P.

Eur J Med Chem. 2008 Sep;43(9):1926-44. doi: 10.1016/j.ejmech.2007.12.001. Epub 2007 Dec 14.

PMID:
18255198

Supplemental Content

Loading ...
Support Center