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Items: 31


IL-10 Has Differential Effects on the Innate and Adaptive Immune Systems of Septic Patients.

Mazer M, Unsinger J, Drewry A, Walton A, Osborne D, Blood T, Hotchkiss R, Remy KE.

J Immunol. 2019 Sep 9. pii: ji1900637. doi: 10.4049/jimmunol.1900637. [Epub ahead of print]


Haptoglobin improves shock, lung injury, and survival in canine pneumonia.

Remy KE, Cortés-Puch I, Solomon SB, Sun J, Pockros BM, Feng J, Lertora JJ, Hantgan RR, Liu X, Perlegas A, Warren HS, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C.

JCI Insight. 2018 Sep 20;3(18). pii: 123013. doi: 10.1172/jci.insight.123013. eCollection 2018 Sep 20.


Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Valentine SL, Bembea MM, Muszynski JA, Cholette JM, Doctor A, Spinella PC, Steiner ME, Tucci M, Hassan NE, Parker RI, Lacroix J, Argent A, Carson JL, Remy KE, Demaret P, Emeriaud G, Kneyber MCJ, Guzzetta N, Hall MW, Macrae D, Karam O, Russell RT, Stricker PA, Vogel AM, Tasker RC, Turgeon AF, Schwartz SM, Willems A, Josephson CD, Luban NLC, Lehmann LE, Stanworth SJ, Zantek ND, Bunchman TE, Cheifetz IM, Fortenberry JD, Delaney M, van de Watering L, Robinson KA, Malone S, Steffen KM, Bateman ST; Pediatric Critical Care Transfusion and Anemia Expertise Initiative (TAXI); Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

Pediatr Crit Care Med. 2018 Sep;19(9):884-898. doi: 10.1097/PCC.0000000000001613.


Recommendations on RBC Transfusion in General Critically Ill Children Based on Hemoglobin and/or Physiologic Thresholds From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Doctor A, Cholette JM, Remy KE, Argent A, Carson JL, Valentine SL, Bateman ST, Lacroix J; Pediatric Critical Care Transfusion and Anemia Expertise Initiative (TAXI); Pediatric Critical Care Blood Research Network (BloodNet), and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

Pediatr Crit Care Med. 2018 Sep;19(9S Suppl 1):S98-S113. doi: 10.1097/PCC.0000000000001590.


Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration.

Thampy LK, Remy KE, Walton AH, Hong Z, Liu K, Liu R, Yi V, Burnham CD, Hotchkiss RS.

PLoS One. 2018 Jun 26;13(6):e0199497. doi: 10.1371/journal.pone.0199497. eCollection 2018.


Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood.

Remy KE, Yazer MH, Saini A, Mehanovic-Varmaz A, Rogers SR, Cap AP, Spinella PC.

J Trauma Acute Care Surg. 2018 Jun;84(6S Suppl 1):S104-S114. doi: 10.1097/TA.0000000000001870.


Successful Surgical Repair and Perioperative Management of 6-Month-Old With Total Anomalous Pulmonary Venous Return in a Developing Country: Considerations for the Treatment of Pulmonary Hypertension.

Gokanapudy LR, Remy KE, Karuppiah S, Melgar Humala EV, Abdullah I, Ruppe MD, Schechter WS, Michler R, Tobias JD.

Cardiol Res. 2018 Feb;9(1):53-58. doi: 10.14740/cr651w. Epub 2018 Feb 11.


Mechanisms of red blood cell transfusion-related immunomodulation.

Remy KE, Hall MW, Cholette J, Juffermans NP, Nicol K, Doctor A, Blumberg N, Spinella PC, Norris PJ, Dahmer MK, Muszynski JA; Pediatric Critical Care Blood Research Network (Blood Net).

Transfusion. 2018 Mar;58(3):804-815. doi: 10.1111/trf.14488. Epub 2018 Jan 30. Review.


Pediatric Anti-N-Methyl-d-Aspartate Receptor Encephalitis: A Review with Pooled Analysis and Critical Care Emphasis.

Remy KE, Custer JW, Cappell J, Foster CB, Garber NA, Walker LK, Simon L, Bagdure D.

Front Pediatr. 2017 Nov 24;5:250. doi: 10.3389/fped.2017.00250. eCollection 2017. Review.


Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support.

Suffredini DA, Cui X, Jaswal D, Remy KE, Li Y, Sun J, Solomon SB, Fitz Y, Moayeri M, Leppla S, Eichacker PQ.

Intensive Care Med Exp. 2017 Oct 23;5(1):48. doi: 10.1186/s40635-017-0159-9.


High-Flow Nasal Cannula Utilization in Pediatric Critical Care.

Coletti KD, Bagdure DN, Walker LK, Remy KE, Custer JW.

Respir Care. 2017 Aug;62(8):1023-1029. doi: 10.4187/respcare.05153. Epub 2017 Jun 6.


Red blood cell storage age - what we know from clinical trials.

Remy KE, Spinella PC.

Expert Rev Hematol. 2016 Nov;9(11):1011-1013. Epub 2016 Oct 8. No abstract available.


Palliative Care-Led Meetings for Families of ICU Patients.

Remy AM, Remy KE, Rosenbaum JL.

JAMA. 2016 Oct 18;316(15):1597-1598. doi: 10.1001/jama.2016.14316. No abstract available.


Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness.

Muszynski JA, Spinella PC, Cholette JM, Acker JP, Hall MW, Juffermans NP, Kelly DP, Blumberg N, Nicol K, Liedel J, Doctor A, Remy KE, Tucci M, Lacroix J, Norris PJ; Pediatric Critical Care Blood Research Network (Blood Net).

Transfusion. 2017 Jan;57(1):195-206. doi: 10.1111/trf.13855. Epub 2016 Oct 2. Review.


High-Flow Oxygen as Noninvasive Ventilation May Complicate Timely Intubation in Patients With Acute Respiratory Distress Syndrome.

Attebery JE, Lin JC, Remy KE.

Crit Care Med. 2016 Aug;44(8):e768-9. doi: 10.1097/CCM.0000000000001782. No abstract available.


Transfusion of recently donated (fresh) red blood cells (RBCs) does not improve survival in comparison with current practice, while safety of the oldest stored units is yet to be established: a meta-analysis.

Remy KE, Sun J, Wang D, Welsh J, Solomon SB, Klein HG, Natanson C, Cortés-Puch I.

Vox Sang. 2016 Jul;111(1):43-54. doi: 10.1111/vox.12380. Epub 2016 Feb 5.


Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies.

Suffredini DA, Sampath-Kumar H, Li Y, Ohanjanian L, Remy KE, Cui X, Eichacker PQ.

Toxins (Basel). 2015 Dec 12;7(12):5417-34. doi: 10.3390/toxins7124891. Review.


In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome.

Cortés-Puch I, Remy KE, Solomon SB, Sun J, Wang D, Al-Hamad M, Kelly SM, Sinchar D, Bellavia L, Kanias T, Popovsky MA, Kim-Shapiro DB, Klein HG, Natanson C.

Transfusion. 2015 Nov;55(11):2564-75. doi: 10.1111/trf.13275. Epub 2015 Sep 7.


High-Flow Nasal Cannula Oxygen in Respiratory Failure.

Shein SL, Remy KE.

N Engl J Med. 2015 Oct;373(14):1374. doi: 10.1056/NEJMc1508390. No abstract available.


Transfused older stored red blood cells improve the clinical course and outcome in a canine lethal hemorrhage and reperfusion model.

Solomon SB, Cortés-Puch I, Sun J, Remy KE, Wang D, Feng J, Khan SS, Sinchar D, Kim-Shapiro DB, Klein HG, Natanson C.

Transfusion. 2015 Nov;55(11):2552-63. doi: 10.1111/trf.13213. Epub 2015 Jul 15.


Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines.

Remy KE, Cui X, Li Y, Sun J, Solomon SB, Fitz Y, Barochia AV, Al-Hamad M, Moayeri M, Leppla SH, Eichacker PQ.

Intensive Care Med Exp. 2015 Dec;3(1):9. doi: 10.1186/s40635-015-0043-4. Epub 2015 Feb 28.


Sedation protocol for critically ill pediatric patients.

Remy KE.

JAMA. 2015 May 5;313(17):1754. doi: 10.1001/jama.2015.3459. No abstract available.


An overview of investigational toxin-directed therapies for the adjunctive management of Bacillus anthracis infection and sepsis.

Ohanjanian L, Remy KE, Li Y, Cui X, Eichacker PQ.

Expert Opin Investig Drugs. 2015;24(7):851-65. doi: 10.1517/13543784.2015.1041587. Epub 2015 Apr 28. Review.


The influence of the storage lesion(s) on pediatric red cell transfusion.

Remy KE, Natanson C, Klein HG.

Curr Opin Pediatr. 2015 Jun;27(3):277-85. doi: 10.1097/MOP.0000000000000224. Review.


Role of granulocyte transfusions in invasive fusariosis: systematic review and single-center experience.

Kadri SS, Remy KE, Strich JR, Gea-Banacloche J, Leitman SF.

Transfusion. 2015 Sep;55(9):2076-85. doi: 10.1111/trf.13099. Epub 2015 Apr 9. Review.


A place at the table for children in the ebola virus disease discussion.

Remy KE, Chertow DS.

Pediatr Crit Care Med. 2015 Feb;16(2):184-5. doi: 10.1097/PCC.0000000000000368. No abstract available.


Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia.

Wang D, Cortés-Puch I, Sun J, Solomon SB, Kanias T, Remy KE, Feng J, Alimchandani M, Quezado M, Helms C, Perlegas A, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C.

Transfusion. 2014 Jul;54(7):1712-24. doi: 10.1111/trf.12607. Epub 2014 Mar 3.


Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia.

Cortés-Puch I, Wang D, Sun J, Solomon SB, Remy KE, Fernandez M, Feng J, Kanias T, Bellavia L, Sinchar D, Perlegas A, Solomon MA, Kelley WE, Popovsky MA, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C.

Blood. 2014 Feb 27;123(9):1403-11. doi: 10.1182/blood-2013-11-539353. Epub 2013 Dec 23.


B. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin components.

Remy KE, Qiu P, Li Y, Cui X, Eichacker PQ.

BMC Med. 2013 Oct 9;11:217. doi: 10.1186/1741-7015-11-217. Review.


Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.

Gallos G, Remy KE, Danielsson J, Funayama H, Fu XW, Chang HY, Yim P, Xu D, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L625-34. doi: 10.1152/ajplung.00068.2013. Epub 2013 Aug 30.


Cerebellar metastatic papillary thyroid carcinoma in a pediatric patient with complex congenital heart disease.

Remy KE, Elder RW, Tsankova NM, Conroy RM.

J Pediatr Endocrinol Metab. 2012;25(11-12):1195-9. doi: 10.1515/jpem-2012-0162.


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