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Items: 10

1.

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.

Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, Böhm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, Kähne T, Sundaravinayagam D, Wolf MJ, Rehrauer H, Koppe C, Speicher T, Padrissa-Altés S, Maire R, Schattenberg JM, Jeong JS, Liu L, Zwirner S, Boger R, Hüser N, Davis RJ, Müllhaupt B, Moch H, Schulze-Bergkamen H, Clavien PA, Werner S, Borsig L, Luther SA, Jost PJ, Weinlich R, Unger K, Behrens A, Hillert L, Dillon C, Di Virgilio M, Wallach D, Dejardin E, Zender L, Naumann M, Walczak H, Green DR, Lopes M, Lavrik I, Luedde T, Heikenwalder M, Weber A.

Cancer Cell. 2017 Sep 11;32(3):342-359.e10. doi: 10.1016/j.ccell.2017.08.010.

2.

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis.

Boutaffala L, Bertrand MJ, Remouchamps C, Seleznik G, Reisinger F, Janas M, Bénézech C, Fernandes MT, Marchetti S, Mair F, Ganeff C, Hupalowska A, Ricci JE, Becher B, Piette J, Knolle P, Caamano J, Vandenabeele P, Heikenwalder M, Dejardin E.

Cell Death Differ. 2015 Dec;22(12):2020-33. doi: 10.1038/cdd.2015.69. Epub 2015 Jun 5.

3.

Methods to assess the activation of the alternative (noncanonical) NF-κB pathway by non-death TNF receptors.

Remouchamps C, Dejardin E.

Methods Mol Biol. 2015;1280:103-19. doi: 10.1007/978-1-4939-2422-6_7.

PMID:
25736746
4.

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, Sprinzl MF, Koppensteiner H, Makowska Z, Volz T, Remouchamps C, Chou WM, Thasler WE, Hüser N, Durantel D, Liang TJ, Münk C, Heim MH, Browning JL, Dejardin E, Dandri M, Schindler M, Heikenwalder M, Protzer U.

Science. 2014 Mar 14;343(6176):1221-8. doi: 10.1126/science.1243462. Epub 2014 Feb 20.

5.

Noncanonical NF-κB signaling is limited by classical NF-κB activity.

Gray CM, Remouchamps C, McCorkell KA, Solt LA, Dejardin E, Orange JS, May MJ.

Sci Signal. 2014 Feb 4;7(311):ra13. doi: 10.1126/scisignal.2004557.

6.

Biology and signal transduction pathways of the Lymphotoxin-αβ/LTβR system.

Remouchamps C, Boutaffala L, Ganeff C, Dejardin E.

Cytokine Growth Factor Rev. 2011 Oct-Dec;22(5-6):301-10. doi: 10.1016/j.cytogfr.2011.11.007. Review.

PMID:
22152226
7.

Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.

Ganeff C, Remouchamps C, Boutaffala L, Benezech C, Galopin G, Vandepaer S, Bouillenne F, Ormenese S, Chariot A, Schneider P, Caamaño J, Piette J, Dejardin E.

Mol Cell Biol. 2011 Nov;31(21):4319-34. doi: 10.1128/MCB.05033-11. Epub 2011 Sep 6.

8.

NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening.

Mortier J, Masereel B, Remouchamps C, Ganeff C, Piette J, Frederick R.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4515-20. doi: 10.1016/j.bmcl.2010.06.027. Epub 2010 Jun 8.

PMID:
20580552
9.

Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation.

Mortier J, Frederick R, Ganeff C, Remouchamps C, Talaga P, Pochet L, Wouters J, Piette J, Dejardin E, Masereel B.

Biochem Pharmacol. 2010 May 15;79(10):1462-72. doi: 10.1016/j.bcp.2010.01.007. Epub 2010 Jan 21.

PMID:
20096267
10.

Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways.

Verhaeghe C, Remouchamps C, Hennuy B, Vanderplasschen A, Chariot A, Tabruyn SP, Oury C, Bours V.

Biochem Pharmacol. 2007 Jun 15;73(12):1982-94. Epub 2007 Mar 24.

PMID:
17466952

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