Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 430

1.

Self-Medication With Over-the-Counter Analgesics: A Survey of Patient Characteristics and Concerns About Pain Medication.

Mehuys E, Crombez G, Paemeleire K, Adriaens E, Van Hees T, Demarche S, Christiaens T, Van Bortel L, Van Tongelen I, Remon JP, Boussery K.

J Pain. 2019 Feb;20(2):215-223. doi: 10.1016/j.jpain.2018.09.003. Epub 2018 Sep 28.

PMID:
30273688
2.

Downscaling of the tableting process: Feasibility of miniaturized forced feeders on a high-speed rotary tablet press.

Grymonpré W, Blahova Prudilova B, Vanhoorne V, Van Snick B, Detobel F, Remon JP, De Beer T, Vervaet C.

Int J Pharm. 2018 Oct 25;550(1-2):477-485. doi: 10.1016/j.ijpharm.2018.09.006. Epub 2018 Sep 6.

PMID:
30196140
3.

In-Depth Evaluation of Data Collected During a Continuous Pharmaceutical Manufacturing Process: A Multivariate Statistical Process Monitoring Approach.

Silva AF, Vercruysse J, Vervaet C, Remon JP, Lopes JA, De Beer T, Sarraguça MC.

J Pharm Sci. 2019 Jan;108(1):439-450. doi: 10.1016/j.xphs.2018.07.033. Epub 2018 Aug 27.

PMID:
30165065
4.

A multivariate raw material property database to facilitate drug product development and enable in-silico design of pharmaceutical dry powder processes.

Van Snick B, Dhondt J, Pandelaere K, Bertels J, Mertens R, Klingeleers D, Di Pretoro G, Remon JP, Vervaet C, De Beer T, Vanhoorne V.

Int J Pharm. 2018 Oct 5;549(1-2):415-435. doi: 10.1016/j.ijpharm.2018.08.014. Epub 2018 Aug 14.

PMID:
30118831
5.

Impact of blend properties on die filling during tableting.

Van Snick B, Grymonpré W, Dhondt J, Pandelaere K, Di Pretoro G, Remon JP, De Beer T, Vervaet C, Vanhoorne V.

Int J Pharm. 2018 Oct 5;549(1-2):476-488. doi: 10.1016/j.ijpharm.2018.08.015. Epub 2018 Aug 11.

PMID:
30107220
6.

Optimizing feed frame design and tableting process parameters to increase die-filling uniformity on a high-speed rotary tablet press.

Grymonpré W, Vanhoorne V, Van Snick B, Blahova Prudilova B, Detobel F, Remon JP, De Beer T, Vervaet C.

Int J Pharm. 2018 Sep 5;548(1):54-61. doi: 10.1016/j.ijpharm.2018.06.047. Epub 2018 Jun 22.

PMID:
29940299
7.

Influence of extended dwell time during pre- and main compression on the properties of ibuprofen tablets.

Peeters E, Silva AFT, Fonteyne M, De Beer T, Vervaet C, Remon JP.

Eur J Pharm Biopharm. 2018 Jul;128:300-315. doi: 10.1016/j.ejpb.2018.05.007. Epub 2018 May 4.

PMID:
29733949
8.

A novel approach to support formulation design on twin screw wet granulation technology: Understanding the impact of overarching excipient properties on drug product quality attributes.

Willecke N, Szepes A, Wunderlich M, Remon JP, Vervaet C, De Beer T.

Int J Pharm. 2018 Jul 10;545(1-2):128-143. doi: 10.1016/j.ijpharm.2018.04.017. Epub 2018 Apr 21.

PMID:
29684559
9.

Process monitoring and evaluation of a continuous pharmaceutical twin-screw granulation and drying process using multivariate data analysis.

Silva AF, Vercruysse J, Vervaet C, Remon JP, Lopes JA, De Beer T, Sarraguça MC.

Eur J Pharm Biopharm. 2018 Jul;128:36-47. doi: 10.1016/j.ejpb.2018.04.011. Epub 2018 Apr 16.

PMID:
29673869
10.

Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer.

De Leersnyder F, Vanhoorne V, Bekaert H, Vercruysse J, Ghijs M, Bostijn N, Verstraeten M, Cappuyns P, Van Assche I, Vander Heyden Y, Ziemons E, Remon JP, Nopens I, Vervaet C, De Beer T.

Eur J Pharm Sci. 2018 Mar 30;115:223-232. doi: 10.1016/j.ejps.2018.01.037.

PMID:
29374528
11.

Downstream processing from melt granulation towards tablets: In-depth analysis of a continuous twin-screw melt granulation process using polymeric binders.

Grymonpré W, Verstraete G, Vanhoorne V, Remon JP, De Beer T, Vervaet C.

Eur J Pharm Biopharm. 2018 Mar;124:43-54. doi: 10.1016/j.ejpb.2017.12.005. Epub 2017 Dec 14.

PMID:
29248561
12.

3D printing of high drug loaded dosage forms using thermoplastic polyurethanes.

Verstraete G, Samaro A, Grymonpré W, Vanhoorne V, Van Snick B, Boone MN, Hellemans T, Van Hoorebeke L, Remon JP, Vervaet C.

Int J Pharm. 2018 Jan 30;536(1):318-325. doi: 10.1016/j.ijpharm.2017.12.002. Epub 2017 Dec 5.

PMID:
29217471
13.

Downstream processing from hot-melt extrusion towards tablets: A quality by design approach.

Grymonpré W, Bostijn N, Herck SV, Verstraete G, Vanhoorne V, Nuhn L, Rombouts P, Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Oct 5;531(1):235-245. doi: 10.1016/j.ijpharm.2017.08.077. Epub 2017 Aug 18.

PMID:
28823887
14.

Development of a continuous direct compression platform for low-dose drug products.

Van Snick B, Holman J, Vanhoorne V, Kumar A, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Aug 30;529(1-2):329-346. doi: 10.1016/j.ijpharm.2017.07.003. Epub 2017 Jul 4.

PMID:
28684361
15.

Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis.

Verstraete G, Vandenbussche L, Kasmi S, Nuhn L, Brouckaert D, Van Renterghem J, Grymonpré W, Vanhoorne V, Coenye T, De Geest BG, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Aug 30;529(1-2):218-226. doi: 10.1016/j.ijpharm.2017.06.076. Epub 2017 Jun 27.

PMID:
28663088
16.

Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process.

Silva AF, Sarraguça MC, Fonteyne M, Vercruysse J, De Leersnyder F, Vanhoorne V, Bostijn N, Verstraeten M, Vervaet C, Remon JP, De Beer T, Lopes JA.

Int J Pharm. 2017 Aug 7;528(1-2):242-252. doi: 10.1016/j.ijpharm.2017.05.075. Epub 2017 Jun 2.

PMID:
28583334
17.
18.

Identifying overarching excipient properties towards an in-depth understanding of process and product performance for continuous twin-screw wet granulation.

Willecke N, Szepes A, Wunderlich M, Remon JP, Vervaet C, De Beer T.

Int J Pharm. 2017 Apr 30;522(1-2):234-247. doi: 10.1016/j.ijpharm.2017.02.028. Epub 2017 Feb 14.

PMID:
28213278
19.

Cranberry extract inhibits in vitro adhesion of F4 and F18+Escherichia coli to pig intestinal epithelium and reduces in vivo excretion of pigs orally challenged with F18+ verotoxigenic E. coli.

Coddens A, Loos M, Vanrompay D, Remon JP, Cox E.

Vet Microbiol. 2017 Apr;202:64-71. doi: 10.1016/j.vetmic.2017.01.019. Epub 2017 Jan 20.

PMID:
28161211
20.

Continuous direct compression as manufacturing platform for sustained release tablets.

Van Snick B, Holman J, Cunningham C, Kumar A, Vercruysse J, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Mar 15;519(1-2):390-407. doi: 10.1016/j.ijpharm.2017.01.010. Epub 2017 Jan 6.

PMID:
28069390
21.

In-line monitoring of compaction properties on a rotary tablet press during tablet manufacturing of hot-melt extruded amorphous solid dispersions.

Grymonpré W, Verstraete G, Van Bockstal PJ, Van Renterghem J, Rombouts P, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2017 Jan 30;517(1-2):348-358. doi: 10.1016/j.ijpharm.2016.12.033. Epub 2016 Dec 14.

PMID:
27988376
22.

The use of partially hydrolysed polyvinyl alcohol for the production of high drug-loaded sustained release pellets via extrusion-spheronisation and coating: In vitro and in vivo evaluation.

Verstraete G, De Jaeghere W, Vercruysse J, Grymonpré W, Vanhoorne V, Stauffer F, De Beer T, Bezuijen A, Remon JP, Vervaet C.

Int J Pharm. 2017 Jan 30;517(1-2):88-95. doi: 10.1016/j.ijpharm.2016.11.067. Epub 2016 Dec 2.

PMID:
27919698
23.

Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy.

Van Renterghem J, Kumar A, Vervaet C, Remon JP, Nopens I, Vander Heyden Y, De Beer T.

Int J Pharm. 2017 Jan 30;517(1-2):119-127. doi: 10.1016/j.ijpharm.2016.11.065. Epub 2016 Dec 1.

PMID:
27916700
24.

Pharmacokinetic analysis of modified-release metoprolol formulations: An interspecies comparison.

De Thaye E, Vervaeck A, Marostica E, Remon JP, Van Bocxlaer J, Vervaet C, Vermeulen A.

Eur J Pharm Sci. 2017 Jan 15;97:135-142. doi: 10.1016/j.ejps.2016.10.039. Epub 2016 Nov 2.

PMID:
27816630
25.

A comparative study between melt granulation/compression and hot melt extrusion/injection molding for the manufacturing of oral sustained release thermoplastic polyurethane matrices.

Verstraete G, Mertens P, Grymonpré W, Van Bockstal PJ, De Beer T, Boone MN, Van Hoorebeke L, Remon JP, Vervaet C.

Int J Pharm. 2016 Nov 20;513(1-2):602-611. doi: 10.1016/j.ijpharm.2016.09.072. Epub 2016 Sep 26.

PMID:
27686052
26.

Blend uniformity evaluation during continuous mixing in a twin screw granulator by in-line NIR using a moving F-test.

Fonteyne M, Vercruysse J, De Leersnyder F, Besseling R, Gerich A, Oostra W, Remon JP, Vervaet C, De Beer T.

Anal Chim Acta. 2016 Sep 7;935:213-23. doi: 10.1016/j.aca.2016.07.020. Epub 2016 Jul 25.

PMID:
27543030
27.

Continuous twin screw granulation of controlled release formulations with various HPMC grades.

Vanhoorne V, Janssens L, Vercruysse J, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2016 Sep 25;511(2):1048-57. doi: 10.1016/j.ijpharm.2016.08.020. Epub 2016 Aug 10.

PMID:
27521702
28.

Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation.

Monteyne T, Adriaensens P, Brouckaert D, Remon JP, Vervaet C, De Beer T.

Int J Pharm. 2016 Oct 15;512(1):158-167. doi: 10.1016/j.ijpharm.2016.07.035. Epub 2016 Jul 21.

PMID:
27452420
29.

Continuous melt granulation: Influence of process and formulation parameters upon granule and tablet properties.

Monteyne T, Vancoillie J, Remon JP, Vervaet C, De Beer T.

Eur J Pharm Biopharm. 2016 Oct;107:249-62. doi: 10.1016/j.ejpb.2016.07.021. Epub 2016 Jul 20.

PMID:
27449628
30.

The use of rheology to elucidate the granulation mechanisms of a miscible and immiscible system during continuous twin-screw melt granulation.

Monteyne T, Heeze L, Mortier ST, Oldörp K, Nopens I, Remon JP, Vervaet C, De Beer T.

Int J Pharm. 2016 Aug 20;510(1):271-84. doi: 10.1016/j.ijpharm.2016.06.055. Epub 2016 Jun 29.

PMID:
27374203
31.

The use of Rheology Combined with Differential Scanning Calorimetry to Elucidate the Granulation Mechanism of an Immiscible Formulation During Continuous Twin-Screw Melt Granulation.

Monteyne T, Heeze L, Mortier ST, Oldörp K, Cardinaels R, Nopens I, Vervaet C, Remon JP, De Beer T.

Pharm Res. 2016 Oct;33(10):2481-94. doi: 10.1007/s11095-016-1973-6. Epub 2016 Jun 22.

PMID:
27335024
32.

Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press.

Peeters E, Vanhoorne V, Vervaet C, Remon JP.

Drug Dev Ind Pharm. 2016 Dec;42(12):2078-2085. Epub 2016 Jun 26.

PMID:
27277525
33.

Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions: In vitro and in vivo characterization.

De Clercq K, Schelfhout C, Bracke M, De Wever O, Van Bockstal M, Ceelen W, Remon JP, Vervaet C.

Biomaterials. 2016 Jul;96:33-46. doi: 10.1016/j.biomaterials.2016.04.012. Epub 2016 Apr 22.

PMID:
27135715
34.

Hydrophilic thermoplastic polyurethanes for the manufacturing of highly dosed oral sustained release matrices via hot melt extrusion and injection molding.

Verstraete G, Van Renterghem J, Van Bockstal PJ, Kasmi S, De Geest BG, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2016 Jun 15;506(1-2):214-21. doi: 10.1016/j.ijpharm.2016.04.057. Epub 2016 Apr 22.

PMID:
27113866
35.

Spectroscopic evaluation of a freeze-dried vaccine during an accelerated stability study.

Hansen L, Van Renterghem J, Daoussi R, Vervaet C, Remon JP, De Beer T.

Eur J Pharm Biopharm. 2016 Jul;104:89-100. doi: 10.1016/j.ejpb.2016.04.010. Epub 2016 Apr 19.

PMID:
27102305
36.

Improved tabletability after a polymorphic transition of delta-mannitol during twin screw granulation.

Vanhoorne V, Bekaert B, Peeters E, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2016 Jun 15;506(1-2):13-24. doi: 10.1016/j.ijpharm.2016.04.025. Epub 2016 Apr 16.

PMID:
27094358
37.

Rationale and Safety Assessment of a Novel Intravaginal Drug-Delivery System with Sustained DL-Lactic Acid Release, Intended for Long-Term Protection of the Vaginal Microbiome.

Verstraelen H, Vervaet C, Remon JP.

PLoS One. 2016 Apr 19;11(4):e0153441. doi: 10.1371/journal.pone.0153441. eCollection 2016.

38.

Analysis of drug use in institutionalized individuals with intellectual disability and tube feeding.

Joos E, Mehuys E, Remon JP, Van Winckel M, Boussery K.

Acta Clin Belg. 2016 Apr;71(2):76-80. doi: 10.1080/17843286.2015.1122332. Epub 2016 Feb 6.

PMID:
27075803
39.

Development of a controlled release formulation by continuous twin screw granulation: Influence of process and formulation parameters.

Vanhoorne V, Vanbillemont B, Vercruysse J, De Leersnyder F, Gomes P, Beer TD, Remon JP, Vervaet C.

Int J Pharm. 2016 May 30;505(1-2):61-8. doi: 10.1016/j.ijpharm.2016.03.058. Epub 2016 Mar 31.

PMID:
27041123
40.

Vibrational spectroscopy to support the link between rheology and continuous twin-screw melt granulation on molecular level: A case study.

Monteyne T, Heeze L, Oldörp K, Vervaet C, Remon JP, De Beer T.

Eur J Pharm Biopharm. 2016 Jun;103:127-135. doi: 10.1016/j.ejpb.2016.03.030. Epub 2016 Apr 1.

PMID:
27040975
41.

The heterogeneity of headache patients who self-medicate: a cluster analysis approach.

Mehuys E, Paemeleire K, Crombez G, Adriaens E, Van Hees T, Demarche S, Christiaens T, Van Bortel L, Van Tongelen I, Remon JP, Boussery K.

Pain. 2016 Jul;157(7):1464-71. doi: 10.1097/j.pain.0000000000000541.

PMID:
26967695
42.

Knowledge of staff members of residential care facilities for individuals with intellectual disability on medication administration via enteral feeding tube.

Joos E, Mehuys E, Van Bocxlaer J, Remon JP, Van Winckel M, Boussery K.

J Intellect Disabil Res. 2016 Nov;60(11):1066-1072. doi: 10.1111/jir.12263. Epub 2016 Mar 4.

PMID:
26939804
43.

Dressings Loaded with Cyclodextrin-Hamamelitannin Complexes Increase Staphylococcus aureus Susceptibility Toward Antibiotics Both in Single as well as in Mixed Biofilm Communities.

Brackman G, Garcia-Fernandez MJ, Lenoir J, De Meyer L, Remon JP, De Beer T, Concheiro A, Alvarez-Lorenzo C, Coenye T.

Macromol Biosci. 2016 Jun;16(6):859-69. doi: 10.1002/mabi.201500437. Epub 2016 Feb 18.

PMID:
26891369
44.

Continuous manufacturing of delta mannitol by cospray drying with PVP.

Vanhoorne V, Van Bockstal PJ, Van Snick B, Peeters E, Monteyne T, Gomes P, De Beer T, Remon JP, Vervaet C.

Int J Pharm. 2016 Mar 30;501(1-2):139-47. doi: 10.1016/j.ijpharm.2016.02.001. Epub 2016 Feb 3.

PMID:
26851355
45.

Effects of lactoferrin treatment on Escherichia coli O157:H7 rectal colonization in cattle.

Rybarczyk J, Kieckens E, De Zutter L, Remon JP, Vanrompay D, Cox E.

Vet Microbiol. 2017 Apr;202:38-46. doi: 10.1016/j.vetmic.2015.12.013. Epub 2015 Dec 29.

PMID:
26791110
46.

Co-extrusion as a processing technique to manufacture a dual sustained release fixed-dose combination product.

Vynckier AK, Voorspoels J, Remon JP, Vervaet C.

J Pharm Pharmacol. 2016 May;68(5):721-7. doi: 10.1111/jphp.12521. Epub 2016 Jan 11.

PMID:
26751978
47.

Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation.

Kumar A, Alakarjula M, Vanhoorne V, Toiviainen M, De Leersnyder F, Vercruysse J, Juuti M, Ketolainen J, Vervaet C, Remon JP, Gernaey KV, De Beer T, Nopens I.

Eur J Pharm Sci. 2016 Jul 30;90:25-37. doi: 10.1016/j.ejps.2015.12.021. Epub 2015 Dec 18.

PMID:
26709082
48.

The impact of hot-melt extrusion on the tableting behaviour of polyvinyl alcohol.

Grymonpré W, De Jaeghere W, Peeters E, Adriaensens P, Remon JP, Vervaet C.

Int J Pharm. 2016 Feb 10;498(1-2):254-62. doi: 10.1016/j.ijpharm.2015.12.020. Epub 2015 Dec 12.

PMID:
26691654
49.

Medication administration via enteral feeding tube: a survey of pharmacists' knowledge.

Joos E, Verbeke S, Mehuys E, Van Bocxlaer J, Remon JP, Van Winckel M, Boussery K.

Int J Clin Pharm. 2016 Feb;38(1):10-5.

PMID:
26464336
50.

Drug administration via enteral feeding tube in residential care facilities for individuals with intellectual disability: A focus group study on guideline implementation.

Joos E, Van Tongelen I, Wijnants K, Mehuys E, Van Bocxlaer J, Remon JP, Grypdonck M, Van Winckel M, Boussery K.

J Intellect Disabil. 2016 Dec;20(4):329-340. Epub 2015 Oct 7.

PMID:
26446830

Supplemental Content

Loading ...
Support Center