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Items: 3

1.

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.

Shi Y, Manis M, Long J, Wang K, Sullivan PM, Remolina Serrano J, Hoyle R, Holtzman DM.

J Exp Med. 2019 Nov 4;216(11):2546-2561. doi: 10.1084/jem.20190980. Epub 2019 Oct 10.

PMID:
31601677
2.

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.

Leyns CEG, Ulrich JD, Finn MB, Stewart FR, Koscal LJ, Remolina Serrano J, Robinson GO, Anderson E, Colonna M, Holtzman DM.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11524-11529. doi: 10.1073/pnas.1710311114. Epub 2017 Oct 9.

3.

AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy.

Ising C, Gallardo G, Leyns CEG, Wong CH, Jiang H, Stewart F, Koscal LJ, Roh J, Robinson GO, Remolina Serrano J, Holtzman DM.

J Exp Med. 2017 May 1;214(5):1227-1238. doi: 10.1084/jem.20162125. Epub 2017 Apr 17. Erratum in: J Exp Med. 2017 May 23;:.

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