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Items: 7

1.

Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes.

Akkina R, Berges BK, Palmer BE, Remling L, Neff CP, Kuruvilla J, Connick E, Folkvord J, Gagliardi K, Kassu A, Akkina SR.

PLoS One. 2011;6(6):e20169. doi: 10.1371/journal.pone.0020169. Epub 2011 Jun 14.

2.

An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.

Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R.

Sci Transl Med. 2011 Jan 19;3(66):66ra6. doi: 10.1126/scitranslmed.3001581.

3.

Humanized Rag2(-/-)gammac(-/-) (RAG-hu) mice can sustain long-term chronic HIV-1 infection lasting more than a year.

Berges BK, Akkina SR, Remling L, Akkina R.

Virology. 2010 Feb 5;397(1):100-3. doi: 10.1016/j.virol.2009.10.034. Epub 2009 Nov 18.

4.

Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes-CCR5 Ribozyme, Tat-rev siRNA, and TAR Decoy-in SCID-hu Mouse-Derived T Cells.

Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R.

Mol Ther. 2007 Jun;15(6):1182-1188. doi: 10.1038/sj.mt.6300157. Epub 2016 Dec 7.

PMID:
28182923
5.

Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells.

Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R.

Mol Ther. 2007 Jun;15(6):1182-8. Epub 2007 Apr 3.

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