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Items: 1 to 50 of 75

1.

Antifungal and anti-inflammatory potential of eschweilenol C-rich fraction derived from Terminalia fagifolia Mart.

Rodrigues de Araújo A, Iles B, de Melo Nogueira K, Dias JDN, Plácido A, Rodrigues A, Albuquerque P, Silva-Pereira I, Socodatto R, Portugal CC, Relvas JB, Costa Véras LM, Dalmatti Alves Lima FC, Batagin-Neto A, Rolim Medeiros JV, Moreira Nunes PH, Eaton P, de Souza de Almeida Leite JR.

J Ethnopharmacol. 2019 Aug 10;240:111941. doi: 10.1016/j.jep.2019.111941. Epub 2019 May 15.

PMID:
31100435
2.

Electrochemical Immunosensor for TNFα-Mediated Inflammatory Disease Screening.

Cruz A, Queirós R, Abreu CM, Barata C, Fernandes R, Silva R, Ambrósio AF, Soares-Dos-Reis R, Guimarães J, Sá MJ, Relvas JB, Freitas PP, Mendes Pinto I.

ACS Chem Neurosci. 2019 Jun 19;10(6):2676-2682. doi: 10.1021/acschemneuro.9b00036. Epub 2019 Apr 18.

PMID:
30985099
3.

Evolvability of the actin cytoskeleton in oligodendrocytes during central nervous system development and aging.

Seixas AI, Azevedo MM, Paes de Faria J, Fernandes D, Mendes Pinto I, Relvas JB.

Cell Mol Life Sci. 2019 Jan;76(1):1-11. doi: 10.1007/s00018-018-2915-8. Epub 2018 Oct 9. Review.

PMID:
30302529
4.

Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics.

Abreu CM, Soares-Dos-Reis R, Melo PN, Relvas JB, Guimarães J, Sá MJ, Cruz AP, Mendes Pinto I.

Front Mol Neurosci. 2018 May 16;11:164. doi: 10.3389/fnmol.2018.00164. eCollection 2018. Review.

5.

Jmy regulates oligodendrocyte differentiation via modulation of actin cytoskeleton dynamics.

Azevedo MM, Domingues HS, Cordelières FP, Sampaio P, Seixas AI, Relvas JB.

Glia. 2018 Sep;66(9):1826-1844. doi: 10.1002/glia.23342. Epub 2018 May 6.

PMID:
29732611
6.

Redox tuning of Ca2+ signaling in microglia drives glutamate release during hypoxia.

Socodato R, Portugal CC, Rodrigues A, Henriques J, Rodrigues C, Figueira C, Relvas JB.

Free Radic Biol Med. 2018 Apr;118:137-149. doi: 10.1016/j.freeradbiomed.2018.02.036. Epub 2018 Mar 2.

PMID:
29501565
7.

The ascorbate transporter SVCT2 to target microglia-dependent inflammation.

Portugal CC, Socodato R, Relvas JB.

Oncotarget. 2017 Nov 7;8(59):99217-99218. doi: 10.18632/oncotarget.22306. eCollection 2017 Nov 21. No abstract available.

8.

Collar occupancy: A new quantitative imaging tool for morphometric analysis of oligodendrocytes.

Bouçanova F, Maia AF, Cruz A, Millar V, Mendes Pinto I, Relvas JB, Domingues HS.

J Neurosci Methods. 2018 Jan 15;294:122-135. doi: 10.1016/j.jneumeth.2017.11.014. Epub 2017 Nov 22.

PMID:
29174019
9.

Structure and function of a novel antioxidant peptide from the skin of tropical frogs.

Barbosa EA, Oliveira A, Plácido A, Socodato R, Portugal CC, Mafud AC, Ombredane AS, Moreira DC, Vale N, Bessa LJ, Joanitti GA, Alves C, Gomes P, Delerue-Matos C, Mascarenhas YP, Marani MM, Relvas JB, Pintado M, Leite JRSA.

Free Radic Biol Med. 2018 Feb 1;115:68-79. doi: 10.1016/j.freeradbiomed.2017.11.001. Epub 2017 Nov 21.

PMID:
29162516
10.

Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity.

Henriques JF, Portugal CC, Canedo T, Relvas JB, Summavielle T, Socodato R.

Toxicol Lett. 2018 Feb;283:21-31. doi: 10.1016/j.toxlet.2017.11.002. Epub 2017 Nov 10. Review.

PMID:
29129797
11.

Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke.

Karabiyik C, Fernandes R, Figueiredo FR, Socodato R, Brakebusch C, Lambertsen KL, Relvas JB, Santos SD.

Brain Pathol. 2018 Jul;28(4):569-580. doi: 10.1111/bpa.12562. Epub 2017 Oct 24.

PMID:
28960571
12.

Mechanical plasticity during oligodendrocyte differentiation and myelination.

Domingues HS, Cruz A, Chan JR, Relvas JB, Rubinstein B, Pinto IM.

Glia. 2018 Jan;66(1):5-14. doi: 10.1002/glia.23206. Epub 2017 Sep 21. Review.

13.

Caveolin-1-mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype.

Portugal CC, Socodato R, Canedo T, Silva CM, Martins T, Coreixas VS, Loiola EC, Gess B, Röhr D, Santiago AR, Young P, Minshall RD, Paes-de-Carvalho R, Ambrósio AF, Relvas JB.

Sci Signal. 2017 Mar 28;10(472). pii: eaal2005. doi: 10.1126/scisignal.aal2005.

PMID:
28351945
14.

Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons.

Braz SO, Cruz A, Lobo A, Bravo J, Moreira-Ribeiro J, Pereira-Castro I, Freitas J, Relvas JB, Summavielle T, Moreira A.

Biochim Biophys Acta Gene Regul Mech. 2017 Jun;1860(6):685-694. doi: 10.1016/j.bbagrm.2017.03.002. Epub 2017 Mar 6.

PMID:
28274785
15.

dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation.

Tavares L, Correia A, Santos MA, Relvas JB, Pereira PS.

PLoS Genet. 2017 Mar 7;13(3):e1006647. doi: 10.1371/journal.pgen.1006647. eCollection 2017 Mar.

16.

Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation.

Socodato R, Santiago FN, Portugal CC, Domith I, Encarnação TG, Loiola EC, Ventura AL, Cossenza M, Relvas JB, Castro NG, Paes-de-Carvalho R.

Sci Rep. 2017 Jan 18;7:40912. doi: 10.1038/srep40912.

17.

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties.

Rosa AI, Grade S, Santos SD, Bernardino L, Chen TC, Relvas J, Hofman FM, Agasse F.

Front Cell Neurosci. 2016 Dec 15;10:284. doi: 10.3389/fncel.2016.00284. eCollection 2016.

18.

Erratum to: Assessment of postoperative pain after reciprocating or rotary NiTi instrumentation of root canals: a randomized, controlled clinical trial.

Relvas JB, Bastos MM, Marques AA, Garrido AD, Herkrath FJ, Sponchiado EC Jr.

Clin Oral Investig. 2016 Nov;20(8):1995. No abstract available.

PMID:
26911493
19.

Assessment of postoperative pain after reciprocating or rotary NiTi instrumentation of root canals: a randomized, controlled clinical trial.

Relvas JB, Bastos MM, Marques AA, Garrido AD, Sponchiado EC Jr.

Clin Oral Investig. 2016 Nov;20(8):1987-1993. Epub 2015 Dec 19. Erratum in: Clin Oral Investig. 2016 Nov;20(8):1995.

PMID:
26685850
20.

Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia.

Gomes JR, Nogueira RS, Vieira M, Santos SD, Ferraz-Nogueira JP, Relvas JB, Saraiva MJ.

Cell Death Differ. 2016 Nov 1;23(11):1749-1764. doi: 10.1038/cdd.2016.64. Epub 2016 Aug 12.

21.

Corrigendum: Oligodendrocyte, Astrocyte and Microglia Crosstalk in Myelin Development, Damage, and Repair.

Domingues HS, Portugal CC, Socodato R, Relvas JB.

Front Cell Dev Biol. 2016 Jul 19;4:79. doi: 10.3389/fcell.2016.00079. eCollection 2016.

22.

Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair.

Domingues HS, Portugal CC, Socodato R, Relvas JB.

Front Cell Dev Biol. 2016 Jun 28;4:71. doi: 10.3389/fcell.2016.00071. eCollection 2016. Review. Erratum in: Front Cell Dev Biol. 2016;4:79.

23.

Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells.

Coelho-Santos V, Socodato R, Portugal C, Leitão RA, Rito M, Barbosa M, Couraud PO, Romero IA, Weksler B, Minshall RD, Fontes-Ribeiro C, Summavielle T, Relvas JB, Silva AP.

Cell Mol Life Sci. 2016 Dec;73(24):4701-4716. Epub 2016 Jul 4.

PMID:
27376435
24.

Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues.

Lourenço T, Paes de Faria J, Bippes CA, Maia J, Lopes-da-Silva JA, Relvas JB, Grãos M.

Sci Rep. 2016 Feb 16;6:21563. doi: 10.1038/srep21563.

25.

Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the glial scar.

Rocha DN, Ferraz-Nogueira JP, Barrias CC, Relvas JB, Pêgo AP.

Front Cell Neurosci. 2015 Sep 29;9:377. doi: 10.3389/fncel.2015.00377. eCollection 2015.

26.

Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia.

Barateiro A, Chen S, Yueh MF, Fernandes A, Domingues HS, Relvas J, Barbier O, Nguyen N, Tukey RH, Brites D.

Mol Pharmacol. 2016 Jan;89(1):84-93. doi: 10.1124/mol.115.098228. Epub 2015 Oct 19.

27.

E-cadherin-defective gastric cancer cells depend on Laminin to survive and invade.

Caldeira J, Figueiredo J, Brás-Pereira C, Carneiro P, Moreira AM, Pinto MT, Relvas JB, Carneiro F, Barbosa M, Casares F, Janody F, Seruca R.

Hum Mol Genet. 2015 Oct 15;24(20):5891-900. doi: 10.1093/hmg/ddv312. Epub 2015 Aug 5.

28.

Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour.

Cardoso AP, Pinto ML, Pinto AT, Pinto MT, Monteiro C, Oliveira MI, Santos SG, Relvas JB, Seruca R, Mantovani A, Mareel M, Barbosa MA, Oliveira MJ.

BMC Cancer. 2015 Jun 5;15:456. doi: 10.1186/s12885-015-1466-8.

29.

Drosophila PS2 and PS3 integrins play distinct roles in retinal photoreceptors-glia interactions.

Tavares L, Pereira E, Correia A, Santos MA, Amaral N, Martins T, Relvas JB, Pereira PS.

Glia. 2015 Jul;63(7):1155-65. doi: 10.1002/glia.22806. Epub 2015 Mar 2.

PMID:
25731761
30.

Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder.

Banca P, Voon V, Vestergaard MD, Philipiak G, Almeida I, Pocinho F, Relvas J, Castelo-Branco M.

Brain. 2015 Mar;138(Pt 3):798-811. doi: 10.1093/brain/awu379. Epub 2015 Jan 6.

31.

c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity.

Socodato R, Portugal CC, Canedo T, Domith I, Oliveira NA, Paes-de-Carvalho R, Relvas JB, Cossenza M.

Free Radic Biol Med. 2015 Feb;79:45-55. doi: 10.1016/j.freeradbiomed.2014.11.019. Epub 2014 Dec 5.

PMID:
25486178
32.

c-Src function is necessary and sufficient for triggering microglial cell activation.

Socodato R, Portugal CC, Domith I, Oliveira NA, Coreixas VS, Loiola EC, Martins T, Santiago AR, Paes-de-Carvalho R, Ambrósio AF, Relvas JB.

Glia. 2015 Mar;63(3):497-511. doi: 10.1002/glia.22767. Epub 2014 Nov 24.

PMID:
25421817
33.

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage.

Leite C, Silva NT, Mendes S, Ribeiro A, de Faria JP, Lourenço T, dos Santos F, Andrade PZ, Cardoso CM, Vieira M, Paiva A, da Silva CL, Cabral JM, Relvas JB, Grãos M.

PLoS One. 2014 Oct 30;9(10):e111059. doi: 10.1371/journal.pone.0111059. eCollection 2014.

34.

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.

Neves-Carvalho A, Logarinho E, Freitas A, Duarte-Silva S, Costa Mdo C, Silva-Fernandes A, Martins M, Serra SC, Lopes AT, Paulson HL, Heutink P, Relvas JB, Maciel P.

Hum Mol Genet. 2015 Jan 1;24(1):100-17. doi: 10.1093/hmg/ddu422. Epub 2014 Aug 20.

35.

Brain activation of the defensive and appetitive survival systems in obsessive compulsive disorder.

Gonçalves ÓF, Soares JM, Carvalho S, Leite J, Ganho A, Fernandes-Gonçalves A, Frank B, Pocinho F, Relvas J, Carracedo A, Sampaio A.

Brain Imaging Behav. 2015 Jun;9(2):255-63. doi: 10.1007/s11682-014-9303-2.

PMID:
24760279
36.

Profilin 1 is required for peripheral nervous system myelination.

Montani L, Buerki-Thurnherr T, de Faria JP, Pereira JA, Dias NG, Fernandes R, Gonçalves AF, Braun A, Benninger Y, Böttcher RT, Costell M, Nave KA, Franklin RJ, Meijer D, Suter U, Relvas JB.

Development. 2014 Apr;141(7):1553-61. doi: 10.1242/dev.101840. Epub 2014 Mar 5.

37.

Endodontic Treatment of Maxillary Premolar with Three Root Canals Using Optical Microscope and NiTi Rotatory Files System.

Relvas JB, de Carvalho FM, Marques AA, Sponchiado EC Jr, Garcia Lda F.

Case Rep Dent. 2013;2013:710408. doi: 10.1155/2013/710408. Epub 2013 Dec 3.

38.

Rat cerebellar slice cultures exposed to bilirubin evidence reactive gliosis, excitotoxicity and impaired myelinogenesis that is prevented by AMPA and TNF-α inhibitors.

Barateiro A, Domingues HS, Fernandes A, Relvas JB, Brites D.

Mol Neurobiol. 2014 Feb;49(1):424-39. doi: 10.1007/s12035-013-8530-7. Epub 2013 Aug 28.

PMID:
23982745
39.

Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y(1086), c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity.

Cardoso AP, Pinto ML, Pinto AT, Oliveira MI, Pinto MT, Gonçalves R, Relvas JB, Figueiredo C, Seruca R, Mantovani A, Mareel M, Barbosa MA, Oliveira MJ.

Oncogene. 2014 Apr 17;33(16):2123-33. doi: 10.1038/onc.2013.154. Epub 2013 May 6.

PMID:
23644655
40.

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.

Horn M, Baumann R, Pereira JA, Sidiropoulos PN, Somandin C, Welzl H, Stendel C, Lühmann T, Wessig C, Toyka KV, Relvas JB, Senderek J, Suter U.

Brain. 2012 Dec;135(Pt 12):3567-83. doi: 10.1093/brain/aws275. Epub 2012 Nov 20.

41.

Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination.

Barateiro A, Miron VE, Santos SD, Relvas JB, Fernandes A, Ffrench-Constant C, Brites D.

Mol Neurobiol. 2013 Apr;47(2):632-44. doi: 10.1007/s12035-012-8364-8. Epub 2012 Oct 21.

PMID:
23086523
42.

Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion.

Socodato R, Santiago FN, Portugal CC, Domingues AF, Santiago AR, Relvas JB, Ambrósio AF, Paes-de-Carvalho R.

J Biol Chem. 2012 Nov 9;287(46):38680-94. doi: 10.1074/jbc.M112.353961. Epub 2012 Sep 19.

43.

Identification of new interacting partners for atypical Rho GTPases: a SILAC-based approach.

Montani L, Bausch-Fluck D, Domingues AF, Wollscheid B, Relvas JB.

Methods Mol Biol. 2012;827:305-17. doi: 10.1007/978-1-61779-442-1_20.

PMID:
22144283
44.

Obsessive Compulsive Disorder as a functional interhemispheric imbalance at the thalamic level.

Gonçalves ÓF, Carvalho S, Leite J, Pocinho F, Relvas J, Fregni F.

Med Hypotheses. 2011 Sep;77(3):445-7. doi: 10.1016/j.mehy.2011.06.004. Epub 2011 Jul 6.

PMID:
21737205
45.

[Cognition, social cognition and functioning in schizophrenia].

Vaz-Serra A, Palha A, Figueira ML, Bessa-Peixoto A, Brissos S, Casquinha P, Damas-Reis F, Ferreira L, Gago J, Jara J, Relvas J, Marques-Teixeira J.

Acta Med Port. 2010 Nov-Dec;23(6):1043-58. Epub 2010 Dec 28. Review. Portuguese.

46.

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

Herzog D, Loetscher P, van Hengel J, Knüsel S, Brakebusch C, Taylor V, Suter U, Relvas JB.

J Neurosci. 2011 Mar 30;31(13):5120-30. doi: 10.1523/JNEUROSCI.4807-10.2011.

47.

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination.

Cotter L, Ozçelik M, Jacob C, Pereira JA, Locher V, Baumann R, Relvas JB, Suter U, Tricaud N.

Science. 2010 Jun 11;328(5984):1415-8. doi: 10.1126/science.1187735. Epub 2010 May 6.

48.

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.

Ozçelik M, Cotter L, Jacob C, Pereira JA, Relvas JB, Suter U, Tricaud N.

J Neurosci. 2010 Mar 17;30(11):4120-31. doi: 10.1523/JNEUROSCI.5185-09.2010.

49.

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system.

Gonçalves AF, Dias NG, Moransard M, Correia R, Pereira JA, Witke W, Suter U, Relvas JB.

Glia. 2010 Apr 15;58(6):706-15. doi: 10.1002/glia.20956.

PMID:
20014276
50.

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system.

Pereira JA, Benninger Y, Baumann R, Gonçalves AF, Ozçelik M, Thurnherr T, Tricaud N, Meijer D, Fässler R, Suter U, Relvas JB.

J Cell Biol. 2009 Apr 6;185(1):147-61. doi: 10.1083/jcb.200809008.

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