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Items: 31

1.

Hybrid modeling frameworks of tumor development and treatment.

Chamseddine IM, Rejniak KA.

Wiley Interdiscip Rev Syst Biol Med. 2020 Jan;12(1):e1461. doi: 10.1002/wsbm.1461. Epub 2019 Jul 17. Review.

2.

Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential.

Karolak A, Poonja S, Rejniak KA.

PLoS Comput Biol. 2019 Jul 16;15(7):e1007214. doi: 10.1371/journal.pcbi.1007214. eCollection 2019 Jul.

3.

Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling.

Karolak A, Estrella VC, Huynh AS, Chen T, Vagner J, Morse DL, Rejniak KA.

Sci Rep. 2018 Feb 26;8(1):3638. doi: 10.1038/s41598-018-21883-z.

4.

Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue.

Karolak A, Rejniak KA.

Bull Math Biol. 2019 Sep;81(9):3623-3641. doi: 10.1007/s11538-018-0402-x. Epub 2018 Feb 8.

PMID:
29423880
5.

Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues.

Karolak A, Markov DA, McCawley LJ, Rejniak KA.

J R Soc Interface. 2018 Jan;15(138). pii: 20170703. doi: 10.1098/rsif.2017.0703. Review.

6.

Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases.

Shah AB, Rejniak KA, Gevertz JL.

Math Biosci Eng. 2016 Dec 1;13(6):1185-1206. doi: 10.3934/mbe.2016038.

7.

Microenvironmental Niches and Sanctuaries: A Route to Acquired Resistance.

Pérez-Velázquez J, Gevertz JL, Karolak A, Rejniak KA.

Adv Exp Med Biol. 2016;936:149-164.

8.
9.

Diagnostic assessment of osteosarcoma chemoresistance based on Virtual Clinical Trials.

Rejniak KA, Lloyd MC, Reed DR, Bui MM.

Med Hypotheses. 2015 Sep;85(3):348-54. doi: 10.1016/j.mehy.2015.06.015. Epub 2015 Jun 24.

10.

Pathology to enhance precision medicine in oncology: lessons from landscape ecology.

Lloyd MC, Rejniak KA, Brown JS, Gatenby RA, Minor ES, Bui MM.

Adv Anat Pathol. 2015 Jul;22(4):267-72. doi: 10.1097/PAP.0000000000000078. Review.

11.

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302.

Wojtkowiak JW, Cornnell HC, Matsumoto S, Saito K, Takakusagi Y, Dutta P, Kim M, Zhang X, Leos R, Bailey KM, Martinez G, Lloyd MC, Weber C, Mitchell JB, Lynch RM, Baker AF, Gatenby RA, Rejniak KA, Hart C, Krishna MC, Gillies RJ.

Cancer Metab. 2015 Jan 29;3(1):2. doi: 10.1186/s40170-014-0026-z. eCollection 2015.

12.

Mechanical aspects of microtubule bundling in taxane-treated circulating tumor cells.

Kim M, Rejniak KA.

Biophys J. 2014 Sep 2;107(5):1236-1246. doi: 10.1016/j.bpj.2014.07.009.

13.

The formation of tight tumor clusters affects the efficacy of cell cycle inhibitors: a hybrid model study.

Kim M, Reed D, Rejniak KA.

J Theor Biol. 2014 Jul 7;352:31-50. doi: 10.1016/j.jtbi.2014.02.027. Epub 2014 Mar 5.

14.

Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues.

Kim M, Gillies RJ, Rejniak KA.

Front Oncol. 2013 Nov 18;3:278. doi: 10.3389/fonc.2013.00278. Review.

15.

Simulating cancer: computational models in oncology.

Enderling H, Rejniak KA.

Front Oncol. 2013 Sep 13;3:233. doi: 10.3389/fonc.2013.00233. eCollection 2013. No abstract available.

16.

The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study.

Rejniak KA, Estrella V, Chen T, Cohen AS, Lloyd MC, Morse DL.

Front Oncol. 2013 May 10;3:111. doi: 10.3389/fonc.2013.00111. eCollection 2013.

17.
18.

Homeostatic imbalance in epithelial ducts and its role in carcinogenesis.

Rejniak KA.

Scientifica (Cairo). 2012;2012:132978. doi: 10.6064/2012/132978. Epub 2012 Jul 12.

19.

State of the art in computational modelling of cancer.

Rejniak KA, Anderson AR.

Math Med Biol. 2012 Mar;29(1):1-2. doi: 10.1093/imammb/dqr029. Epub 2011 Dec 26. No abstract available.

PMID:
22200587
20.

Cellular modeling of cancer invasion: integration of in silico and in vitro approaches.

Kam Y, Rejniak KA, Anderson AR.

J Cell Physiol. 2012 Feb;227(2):431-8. doi: 10.1002/jcp.22766. Review.

21.

Computational investigation of intrinsic and extrinsic mechanisms underlying the formation of carcinoma.

Rejniak KA, Quaranta V, Anderson AR.

Math Med Biol. 2012 Mar;29(1):67-84. doi: 10.1093/imammb/dqq021. Epub 2010 Nov 24.

22.

Hybrid models of tumor growth.

Rejniak KA, Anderson AR.

Wiley Interdiscip Rev Syst Biol Med. 2011 Jan-Feb;3(1):115-25. doi: 10.1002/wsbm.102. Review.

23.

Linking changes in epithelial morphogenesis to cancer mutations using computational modeling.

Rejniak KA, Wang SE, Bryce NS, Chang H, Parvin B, Jourquin J, Estrada L, Gray JW, Arteaga CL, Weaver AM, Quaranta V, Anderson AR.

PLoS Comput Biol. 2010 Aug 26;6(8). pii: e1000900. doi: 10.1371/journal.pcbi.1000900.

24.

Current trends in mathematical modeling of tumor-microenvironment interactions: a survey of tools and applications.

Rejniak KA, McCawley LJ.

Exp Biol Med (Maywood). 2010 Apr;235(4):411-23. doi: 10.1258/ebm.2009.009230. Review.

PMID:
20407073
25.

Microenvironment driven invasion: a multiscale multimodel investigation.

Anderson AR, Rejniak KA, Gerlee P, Quaranta V.

J Math Biol. 2009 Apr;58(4-5):579-624. doi: 10.1007/s00285-008-0210-2. Epub 2008 Oct 7.

26.

Invasion emerges from cancer cell adaptation to competitive microenvironments: quantitative predictions from multiscale mathematical models.

Quaranta V, Rejniak KA, Gerlee P, Anderson AR.

Semin Cancer Biol. 2008 Oct;18(5):338-48. doi: 10.1016/j.semcancer.2008.03.018. Epub 2008 Apr 1. Review.

27.

A computational study of the development of epithelial acini: II. Necessary conditions for structure and lumen stability.

Rejniak KA, Anderson AR.

Bull Math Biol. 2008 Jul;70(5):1450-79. doi: 10.1007/s11538-008-9308-3. Epub 2008 Apr 10.

28.

A computational study of the development of epithelial acini: I. Sufficient conditions for the formation of a hollow structure.

Rejniak KA, Anderson AR.

Bull Math Biol. 2008 Apr;70(3):677-712. doi: 10.1007/s11538-007-9274-1. Epub 2008 Jan 11.

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31.

A computational model of the mechanics of growth of the villous trophoblast bilayer.

Rejniak KA, Kliman HJ, Fauci LJ.

Bull Math Biol. 2004 Mar;66(2):199-232.

PMID:
14871565

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