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Items: 1 to 50 of 205

1.

Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 2: Spheroids, Organoids, and Disease Modeling.

Eglen RM, Reisine T.

SLAS Technol. 2019 Feb;24(1):18-27. doi: 10.1177/2472630318803275.

PMID:
30798678
2.

Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 1: Target Identification and Lead Optimization.

Eglen RM, Reisine T.

SLAS Technol. 2019 Feb;24(1):3-17. doi: 10.1177/2472630318803277. Epub 2018 Oct 4.

PMID:
30286296
3.

Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview.

Eglen RM, Reisine T.

J Biomol Screen. 2011 Dec;16(10):1137-52. doi: 10.1177/1087057111417871. Epub 2011 Oct 14. Review.

PMID:
22002420
4.

Drug discovery and the human kinome: recent trends.

Eglen R, Reisine T.

Pharmacol Ther. 2011 May;130(2):144-56. doi: 10.1016/j.pharmthera.2011.01.007. Epub 2011 Jan 20. Review.

PMID:
21256157
5.

Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening.

Eglen R, Reisine T.

Assay Drug Dev Technol. 2011 Apr;9(2):108-24. doi: 10.1089/adt.2010.0305. Epub 2010 Dec 27. Review.

PMID:
21186936
6.

Human kinome drug discovery and the emerging importance of atypical allosteric inhibitors.

Eglen RM, Reisine T.

Expert Opin Drug Discov. 2010 Mar;5(3):277-90. doi: 10.1517/17460441003636820. Epub 2010 Feb 18.

PMID:
22823023
7.

New insights into GPCR function: implications for HTS.

Eglen RM, Reisine T.

Methods Mol Biol. 2009;552:1-13. doi: 10.1007/978-1-60327-317-6_1. Review.

PMID:
19513638
8.

The current status of drug discovery against the human kinome.

Eglen RM, Reisine T.

Assay Drug Dev Technol. 2009 Feb;7(1):22-43. doi: 10.1089/adt.2008.164. Review.

PMID:
19382888
9.

Photoproteins: important new tools in drug discovery.

Eglen RM, Reisine T.

Assay Drug Dev Technol. 2008 Oct;6(5):659-71. doi: 10.1089/adt.2008.160. Review.

PMID:
19035847
10.

An overview of drug screening using primary and embryonic stem cells.

Eglen RM, Gilchrist A, Reisine T.

Comb Chem High Throughput Screen. 2008 Aug;11(7):566-72. Review.

PMID:
18694393
11.

The use of immortalized cell lines in GPCR screening: the good, bad and ugly.

Eglen RM, Gilchrist A, Reisine T.

Comb Chem High Throughput Screen. 2008 Aug;11(7):560-5. Review.

PMID:
18694392
12.

The use of AlphaScreen technology in HTS: current status.

Eglen RM, Reisine T, Roby P, Rouleau N, Illy C, Bossé R, Bielefeld M.

Curr Chem Genomics. 2008 Feb 25;1:2-10. doi: 10.2174/1875397300801010002.

13.
14.

Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease.

Hook V, Toneff T, Bogyo M, Greenbaum D, Medzihradszky KF, Neveu J, Lane W, Hook G, Reisine T.

Biol Chem. 2005 Sep;386(9):931-40. Erratum in: Biol Chem. 2005 Dec;386(12):1325.

PMID:
16164418
17.

Endomorphin-1: induction of motor behavior and lack of receptor desensitization.

Mehta A, Bot G, Reisine T, Chesselet MF.

J Neurosci. 2001 Jun 15;21(12):4436-42.

18.

Template-constrained cyclic peptide analogues of somatostatin: subtype-selective binding to somatostatin receptors and antiangiogenic activity.

Suich DJ, Mousa SA, Singh G, Liapakis G, Reisine T, DeGrado WF.

Bioorg Med Chem. 2000 Sep;8(9):2229-41.

PMID:
11026536
19.

Differential regulation of the cloned kappa and mu opioid receptors.

Tallent M, Dichter MA, Reisine T.

Neuroscience. 1998 Aug;85(3):873-85.

PMID:
9639280
20.

Fentanyl and its analogs desensitize the cloned mu opioid receptor.

Bot G, Blake AD, Li S, Reisine T.

J Pharmacol Exp Ther. 1998 Jun;285(3):1207-18.

PMID:
9618424
21.

Mutagenesis of the mouse delta opioid receptor converts (-)-buprenorphine from a partial agonist to an antagonist.

Bot G, Blake AD, Li S, Reisine T.

J Pharmacol Exp Ther. 1998 Jan;284(1):283-90.

PMID:
9435189
22.

Mutagenesis of a single amino acid in the rat mu-opioid receptor discriminates ligand binding.

Bot G, Blake AD, Li S, Reisine T.

J Neurochem. 1998 Jan;70(1):358-65.

23.

Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.

Bot G, Blake AD, Li S, Reisine T.

Mol Pharmacol. 1997 Aug;52(2):272-81.

PMID:
9271350
24.

Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.

Osapay G, Prokai L, Kim HS, Medzihradszky KF, Coy DH, Liapakis G, Reisine T, Melacini G, Zhu Q, Wang SH, Mattern RH, Goodman M.

J Med Chem. 1997 Jul 4;40(14):2241-51.

PMID:
9216843
25.
26.

Differential agonist regulation of the human kappa-opioid receptor.

Blake AD, Bot G, Li S, Freeman JC, Reisine T.

J Neurochem. 1997 May;68(5):1846-52.

27.

Differential opioid agonist regulation of the mouse mu opioid receptor.

Blake AD, Bot G, Freeman JC, Reisine T.

J Biol Chem. 1997 Jan 10;272(2):782-90.

28.

Molecular regulation of opioid receptors.

Blake AD, Bot G, Tallent M, Law SF, Li S, Freeman JC, Reisine T.

Receptors Channels. 1997;5(3-4):231-5. Review.

PMID:
9606728
29.
30.
31.

International Union of Pharmacology. XII. Classification of opioid receptors.

Dhawan BN, Cesselin F, Raghubir R, Reisine T, Bradley PB, Portoghese PS, Hamon M.

Pharmacol Rev. 1996 Dec;48(4):567-92. Review. No abstract available.

PMID:
8981566
32.

Identification of ligand binding determinants in the somatostatin receptor subtypes 1 and 2.

Liapakis G, Fitzpatrick D, Hoeger C, Rivier J, Vandlen R, Reisine T.

J Biol Chem. 1996 Aug 23;271(34):20331-9.

33.

Evidence that a novel somatostatin receptor couples to an inward rectifier potassium current in AtT-20 cells.

Tallent M, Dichter MA, Reisine T.

Neuroscience. 1996 Aug;73(3):855-64.

PMID:
8809804
34.

Molecular and functional properties of somatostain receptor subtypes.

Liapakis G, Tallent M, Reisine T.

Metabolism. 1996 Aug;45(8 Suppl 1):12-3. Review.

PMID:
8769370
35.

Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20.

Tallent M, Liapakis G, O'Carroll AM, Lolait SJ, Dichter M, Reisine T.

Neuroscience. 1996 Apr;71(4):1073-81.

PMID:
8684611
36.

Molecular mechanisms of opiate receptor coupling to G proteins and effector systems.

Reisine T, Law SF, Blake A, Tallent M.

Ann N Y Acad Sci. 1996 Mar 22;780:168-75. Review. No abstract available.

PMID:
8602730
37.

Development of a selective agonist at the somatostatin receptor subtype sstr1.

Liapakis G, Hoeger C, Rivier J, Reisine T.

J Pharmacol Exp Ther. 1996 Mar;276(3):1089-94.

PMID:
8786539
38.

Molecular biology of opioid receptors.

Raynor K, Kong H, Law S, Heerding J, Tallent M, Livingston F, Hines J, Reisine T.

NIDA Res Monogr. 1996;161:83-103. Review. No abstract available.

PMID:
8784846
39.

Somatostatin.

Reisine T.

Cell Mol Neurobiol. 1995 Dec;15(6):597-614. Review.

PMID:
8719032
40.

Somatostatin receptors.

Reisine T.

Am J Physiol. 1995 Dec;269(6 Pt 1):G813-20. Review.

PMID:
8572211
41.

Alteration of OBCAM conformation as a result of opioid receptor expression and opioid ligand treatment.

Lane CM, Jones CR, Reisine T, Yu L, Lee NM.

Brain Res. 1995 Nov 6;698(1-2):15-22.

PMID:
8581474
42.

Molecular biology of somatostatin receptors.

Reisine T, Bell GI.

Endocr Rev. 1995 Aug;16(4):427-42. Review. No abstract available.

PMID:
8521788
43.

Molecular properties of somatostatin receptors.

Reisine T, Bell GI.

Neuroscience. 1995 Aug;67(4):777-90. Review.

PMID:
7675204
44.

Opiate receptors.

Reisine T.

Neuropharmacology. 1995 May;34(5):463-72. Review. No abstract available.

PMID:
7566479
45.

Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.

Buscail L, Estève JP, Saint-Laurent N, Bertrand V, Reisine T, O'Carroll AM, Bell GI, Schally AV, Vaysse N, Susini C.

Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1580-4.

46.

Characterization of the cloned human mu opioid receptor.

Raynor K, Kong H, Mestek A, Bye LS, Tian M, Liu J, Yu L, Reisine T.

J Pharmacol Exp Ther. 1995 Jan;272(1):423-8.

PMID:
7815359
47.

Molecular biology of somatostatin receptors.

Bell GI, Yasuda K, Kong H, Law SF, Raynor K, Reisine T.

Ciba Found Symp. 1995;190:65-79; discussion 80-8. Review.

PMID:
7587653
48.

Interaction of somatostatin receptors with G proteins and cellular effector systems.

Reisine T, Woulfe D, Raynor K, Kong H, Heerding J, Hines J, Tallent M, Law S.

Ciba Found Symp. 1995;190:160-7; discussion 167-70. Review.

PMID:
7587645
49.

Somatostatin receptor activation of cellular effector systems.

Law SF, Woulfe D, Reisine T.

Cell Signal. 1995 Jan;7(1):1-8. Review.

PMID:
7538774
50.

The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells.

Tallent M, Dichter MA, Bell GI, Reisine T.

Neuroscience. 1994 Dec;63(4):1033-40.

PMID:
7700508

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