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Items: 1 to 50 of 287

1.

Toll-like receptors control p38 and JNK MAPK signaling pathways in rat astrocytes differently, when cultured in normal or high glucose concentrations.

Chistyakov DV, Azbukina NV, Astakhova AA, Polozhintsev AI, Sergeeva MG, Reiser G.

Neurochem Int. 2019 Dec;131:104513. doi: 10.1016/j.neuint.2019.104513. Epub 2019 Jul 29.

PMID:
31369777
2.

Cemented Femoral Component Use in Hip Arthroplasty.

Scanelli JA, Reiser GR, Sloboda JF, Moskal JT.

J Am Acad Orthop Surg. 2019 Feb 15;27(4):119-127. doi: 10.5435/JAAOS-D-17-00245. Review.

PMID:
30531379
3.

Regulation of the ARE-binding proteins, TTP (tristetraprolin) and HuR (human antigen R), in inflammatory response in astrocytes.

Astakhova AA, Chistyakov DV, Sergeeva MG, Reiser G.

Neurochem Int. 2018 Sep;118:82-90. doi: 10.1016/j.neuint.2018.04.014. Epub 2018 Apr 24.

PMID:
29702146
4.

Astrocytes synthesize primary and cyclopentenone prostaglandins that are negative regulators of their proliferation.

Chistyakov DV, Grabeklis S, Goriainov SV, Chistyakov VV, Sergeeva MG, Reiser G.

Biochem Biophys Res Commun. 2018 Jun 2;500(2):204-210. doi: 10.1016/j.bbrc.2018.04.040. Epub 2018 Apr 13.

PMID:
29634926
5.

The small heat shock proteins, especially HspB4 and HspB5 are promising protectants in neurodegenerative diseases.

Zhu Z, Reiser G.

Neurochem Int. 2018 May;115:69-79. doi: 10.1016/j.neuint.2018.02.006. Epub 2018 Feb 7. Review.

PMID:
29425965
6.

Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration.

Schönfeld P, Reiser G.

Neurochem Int. 2017 Oct;109:68-77. doi: 10.1016/j.neuint.2017.03.018. Epub 2017 Mar 30. Review.

PMID:
28366720
7.

Neurons and astrocytes in an infantile neuroaxonal dystrophy (INAD) mouse model show characteristic alterations in glutamate-induced Ca2+ signaling.

Strokin M, Reiser G.

Neurochem Int. 2017 Sep;108:121-132. doi: 10.1016/j.neuint.2017.03.004. Epub 2017 Mar 6.

PMID:
28279750
8.

Recent progress in translational research on neurovascular and neurodegenerative disorders.

Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors.

Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Review.

9.

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.

Daly MB, Pilarski R, Berry M, Buys SS, Farmer M, Friedman S, Garber JE, Kauff ND, Khan S, Klein C, Kohlmann W, Kurian A, Litton JK, Madlensky L, Merajver SD, Offit K, Pal T, Reiser G, Shannon KM, Swisher E, Vinayak S, Voian NC, Weitzel JN, Wick MJ, Wiesner GL, Dwyer M, Darlow S.

J Natl Compr Canc Netw. 2017 Jan;15(1):9-20.

PMID:
28040716
10.
11.

Erratum to: The intracellular carboxyl tail of the PAR-2 receptor controls intracellular signaling and cell death.

Zhu Z, Stricker R, Yu Li R, Zündorf G, Reiser G.

Cell Tissue Res. 2016 Oct;366(1):243-244. No abstract available.

PMID:
27230229
12.

Brain Lipotoxicity of Phytanic Acid and Very Long-chain Fatty Acids. Harmful Cellular/Mitochondrial Activities in Refsum Disease and X-Linked Adrenoleukodystrophy.

Schönfeld P, Reiser G.

Aging Dis. 2016 Mar 15;7(2):136-49. doi: 10.14336/AD.2015.0823. eCollection 2016 Mar. Review.

13.

Inhibition of β-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration.

Schönfeld P, Reiser G.

J Cereb Blood Flow Metab. 2017 Mar;37(3):848-854. doi: 10.1177/0271678X16642448. Epub 2016 Jul 20.

14.

Nucleotides protect rat brain astrocytes against hydrogen peroxide toxicity and induce antioxidant defense via P2Y receptors.

Förster D, Reiser G.

Neurochem Int. 2016 Mar;94:57-66. doi: 10.1016/j.neuint.2016.02.006. Epub 2016 Feb 17.

PMID:
26898403
15.

Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015.

Daly MB, Pilarski R, Axilbund JE, Berry M, Buys SS, Crawford B, Farmer M, Friedman S, Garber JE, Khan S, Klein C, Kohlmann W, Kurian A, Litton JK, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Rana H, Reiser G, Robson ME, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wick MJ, Wiesner GL, Dwyer M, Kumar R, Darlow S.

J Natl Compr Canc Netw. 2016 Feb;14(2):153-62.

PMID:
26850485
16.
17.

Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria.

Azarashvili T, Krestinina O, Baburina Y, Odinokova I, Grachev D, Papadopoulos V, Akatov V, Lemasters JJ, Reiser G.

Arch Biochem Biophys. 2015 Dec 1;587:70-7. doi: 10.1016/j.abb.2015.10.012. Epub 2015 Oct 20.

18.

Breast Cancer and Non-Hodgkin Lymphoma in a Young Male with Cowden Syndrome.

Hagelstrom RT, Ford J, Reiser GM, Nelson M, Pickering DL, Althof PA, Sanger WG, Coccia PF.

Pediatr Blood Cancer. 2016 Mar;63(3):544-6. doi: 10.1002/pbc.25796. Epub 2015 Oct 15.

PMID:
26468640
19.

Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action.

Azran S, Danino O, Förster D, Kenigsberg S, Reiser G, Dixit M, Singh V, Major DT, Fischer B.

J Med Chem. 2015 Nov 12;58(21):8427-43. doi: 10.1021/acs.jmedchem.5b00575. Epub 2015 Oct 16.

PMID:
26447940
20.
21.

Mitochondrial 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) interacts with mPTP modulators and functional complexes (I-V) coupled with release of apoptotic factors.

Baburina Y, Azarashvili T, Grachev D, Krestinina O, Galvita A, Stricker R, Reiser G.

Neurochem Int. 2015 Nov;90:46-55. doi: 10.1016/j.neuint.2015.07.012. Epub 2015 Jul 15.

PMID:
26188334
22.

Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria.

Zhu Z, Li R, Stricker R, Reiser G.

Brain Res. 2015 Sep 16;1620:17-28. doi: 10.1016/j.brainres.2015.05.011. Epub 2015 May 18.

PMID:
25998538
23.

Regulation of peroxisome proliferator-activated receptors (PPAR) α and -γ of rat brain astrocytes in the course of activation by toll-like receptor agonists.

Chistyakov DV, Aleshin SE, Astakhova AA, Sergeeva MG, Reiser G.

J Neurochem. 2015 Jul;134(1):113-24. doi: 10.1111/jnc.13101. Epub 2015 Apr 16.

24.
25.

The intracellular carboxyl tail of the PAR-2 receptor controls intracellular signaling and cell death.

Zhu Z, Stricker R, Li Ry, Zündorf G, Reiser G.

Cell Tissue Res. 2015 Mar;359(3):817-27. doi: 10.1007/s00441-014-2056-9. Epub 2014 Dec 19. Erratum in: Cell Tissue Res. 2016 Oct;366(1):243-4.

PMID:
25519044
26.
27.

In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNP) and subsequently increased permeability transition in brain mitochondria in old animals.

Krestinina O, Azarashvili T, Baburina Y, Galvita A, Grachev D, Stricker R, Reiser G.

Neurochem Int. 2015 Jan;80:41-50. doi: 10.1016/j.neuint.2014.09.008. Epub 2014 Sep 30.

PMID:
25277077
28.

Platform switching and abutment emergence profile modification on peri-implant soft tissue.

Dornbush JR, Reiser GM, Ho DK.

Alpha Omegan. 2014 Summer;107(2):28-32.

PMID:
25269220
29.

Genetic/familial high-risk assessment: breast and ovarian, version 1.2014.

Daly MB, Pilarski R, Axilbund JE, Buys SS, Crawford B, Friedman S, Garber JE, Horton C, Kaklamani V, Klein C, Kohlmann W, Kurian A, Litton J, Madlensky L, Marcom PK, Merajver SD, Offit K, Pal T, Pasche B, Reiser G, Shannon KM, Swisher E, Voian NC, Weitzel JN, Whelan A, Wiesner GL, Dwyer MA, Kumar R; National comprehensive cancer network.

J Natl Compr Canc Netw. 2014 Sep;12(9):1326-38.

PMID:
25190698
30.

Carbenoxolone induces permeability transition pore opening in rat mitochondria via the translocator protein TSPO and connexin43.

Azarashvili T, Baburina Y, Grachev D, Krestinina O, Papadopoulos V, Lemasters JJ, Odinokova I, Reiser G.

Arch Biochem Biophys. 2014 Sep 15;558:87-94. doi: 10.1016/j.abb.2014.06.027. Epub 2014 Jul 1.

31.

5-OMe-uridine-5'-O-(α-boranodiphosphate), a novel nucleotide derivative highly active at the human P2Y(6) receptor protects against death-receptor mediated glial apoptosis.

Haas M, Ginsburg-Shmuel T, Fischer B, Reiser G.

Neurosci Lett. 2014 Aug 22;578:80-4. doi: 10.1016/j.neulet.2014.06.030. Epub 2014 Jun 23.

PMID:
24970757
32.
34.

Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(α or γ)-thio-(α,β- or β,γ)-methylenetriphosphate scaffold.

Nadel Y, Lecka J, Gilad Y, Ben-David G, Förster D, Reiser G, Kenigsberg S, Camden J, Weisman GA, Senderowitz H, Sévigny J, Fischer B.

J Med Chem. 2014 Jun 12;57(11):4677-91. doi: 10.1021/jm500196c. Epub 2014 May 30.

35.

Regulation of peroxisome proliferator-activated receptor β/δ expression and activity levels by toll-like receptor agonists and MAP kinase inhibitors in rat astrocytes.

Chistyakov DV, Aleshin S, Sergeeva MG, Reiser G.

J Neurochem. 2014 Aug;130(4):563-74. doi: 10.1111/jnc.12757. Epub 2014 May 28.

36.

Adults' perceptions of genetic counseling and genetic testing.

Houfek JF, Soltis-Vaughan BS, Atwood JR, Reiser GM, Schaefer GB.

Appl Nurs Res. 2015 Feb;28(1):25-30. doi: 10.1016/j.apnr.2014.03.001. Epub 2014 Mar 13.

PMID:
24794711
37.

Identification of phosphorylated form of 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) as 46 kDa phosphoprotein in brain non-synaptic mitochondria overloaded by calcium.

Azarashvili T, Krestinina O, Galvita A, Grachev D, Baburina Y, Stricker R, Reiser G.

J Bioenerg Biomembr. 2014 Apr;46(2):135-45. doi: 10.1007/s10863-014-9541-4. Epub 2014 Feb 18.

PMID:
24532135
38.

Alanine-(87)-threonine polymorphism impairs signaling and internalization of the human P2Y11 receptor, when co-expressed with the P2Y1 receptor.

Haas M, Shaaban A, Reiser G.

J Neurochem. 2014 May;129(4):602-13. doi: 10.1111/jnc.12666. Epub 2014 Feb 13.

39.
40.
41.

Nardilysin, ADAM10, and Alzheimer's disease: of mice and men.

Bernstein HG, Steiner J, Bogerts B, Stricker R, Reiser G.

Neurobiol Aging. 2014 Mar;35(3):e1. doi: 10.1016/j.neurobiolaging.2013.08.028. Epub 2013 Oct 4. No abstract available.

PMID:
24099785
42.

Role of the peroxisome proliferator-activated receptors (PPAR)-α, β/δ and γ triad in regulation of reactive oxygen species signaling in brain.

Aleshin S, Reiser G.

Biol Chem. 2013 Dec;394(12):1553-70. doi: 10.1515/hsz-2013-0215. Review.

PMID:
24021597
43.

Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain.

Schönfeld P, Reiser G.

J Cereb Blood Flow Metab. 2013 Oct;33(10):1493-9. doi: 10.1038/jcbfm.2013.128. Epub 2013 Aug 7. Review.

44.

Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses.

Aleshin S, Strokin M, Sergeeva M, Reiser G.

Neurochem Int. 2013 Oct;63(4):322-30. doi: 10.1016/j.neuint.2013.06.012. Epub 2013 Jun 25. Review.

PMID:
23811400
45.

Sp-2-propylthio-ATP-α-B and Sp-2-propylthio-ATP-α-B,β-γ-dichloromethylene are novel potent and specific agonists of the human P2Y₁₁ receptor.

Haas M, Ben-Moshe I, Fischer B, Reiser G.

Biochem Pharmacol. 2013 Sep 1;86(5):645-55. doi: 10.1016/j.bcp.2013.06.013. Epub 2013 Jun 25.

PMID:
23810430
46.

Highly efficient biocompatible neuroprotectants with dual activity as antioxidants and P2Y receptor agonists.

Azran S, Förster D, Danino O, Nadel Y, Reiser G, Fischer B.

J Med Chem. 2013 Jun 27;56(12):4938-52. doi: 10.1021/jm400197m. Epub 2013 Jun 10.

PMID:
23751098
47.

NF-κB-dependent and -independent pathways in the protective effects of activated protein C in hippocampal and cortical neurons at excitotoxicity.

Gorbacheva L, Strukova S, Pinelis V, Ishiwata S, Stricker R, Reiser G.

Neurochem Int. 2013 Aug;63(2):101-11. doi: 10.1016/j.neuint.2013.05.008. Epub 2013 May 28.

PMID:
23727063
48.

Nardilysin in human brain diseases: both friend and foe.

Bernstein HG, Stricker R, Dobrowolny H, Steiner J, Bogerts B, Trübner K, Reiser G.

Amino Acids. 2013 Aug;45(2):269-78. doi: 10.1007/s00726-013-1499-8. Epub 2013 Apr 19. Review.

PMID:
23604405
49.

Decreased expression of nardilysin in SH-SY5Y cells under ethanol stress and reduced density of nardilysin-expressing neurons in brains of alcoholics.

Bernstein HG, Stricker R, Zschiebsch K, Müller S, Dobrowolny H, Steiner J, Bogerts B, Reiser G.

J Psychiatr Res. 2013 Mar;47(3):343-9. doi: 10.1016/j.jpsychires.2012.11.006. Epub 2012 Dec 6.

PMID:
23219461
50.

UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety.

Ginsburg-Shmuel T, Haas M, Grbic D, Arguin G, Nadel Y, Gendron FP, Reiser G, Fischer B.

Bioorg Med Chem. 2012 Sep 15;20(18):5483-95. doi: 10.1016/j.bmc.2012.07.042. Epub 2012 Aug 2.

PMID:
22901672

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