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Items: 20


OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma.

Reinke SN, Galindo-Prieto B, Skotare T, Broadhurst DI, Singhania A, Horowitz D, Djukanović R, Hinks TSC, Geladi P, Trygg J, Wheelock CE.

Anal Chem. 2018 Nov 20;90(22):13400-13408. doi: 10.1021/acs.analchem.8b03205. Epub 2018 Nov 2.


Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies.

Broadhurst D, Goodacre R, Reinke SN, Kuligowski J, Wilson ID, Lewis MR, Dunn WB.

Metabolomics. 2018;14(6):72. doi: 10.1007/s11306-018-1367-3. Epub 2018 May 18. Review.


Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD.

Naz S, Kolmert J, Yang M, Reinke SN, Kamleh MA, Snowden S, Heyder T, Levänen B, Erle DJ, Sköld CM, Wheelock ÅM, Wheelock CE.

Eur Respir J. 2017 Jun 22;49(6). pii: 1602322. doi: 10.1183/13993003.02322-2016. Print 2017 Jun.


Development of a Liquid Chromatography-High Resolution Mass Spectrometry Metabolomics Method with High Specificity for Metabolite Identification Using All Ion Fragmentation Acquisition.

Naz S, Gallart-Ayala H, Reinke SN, Mathon C, Blankley R, Chaleckis R, Wheelock CE.

Anal Chem. 2017 Aug 1;89(15):7933-7942. doi: 10.1021/acs.analchem.7b00925. Epub 2017 Jul 12.


Metabolomics analysis identifies different metabotypes of asthma severity.

Reinke SN, Gallart-Ayala H, Gómez C, Checa A, Fauland A, Naz S, Kamleh MA, Djukanović R, Hinks TS, Wheelock CE.

Eur Respir J. 2017 Mar 29;49(3). pii: 1601740. doi: 10.1183/13993003.01740-2016. Print 2017 Mar.


Early Cord Metabolite Index and Outcome in Perinatal Asphyxia and Hypoxic-Ischaemic Encephalopathy.

Ahearne CE, Denihan NM, Walsh BH, Reinke SN, Kenny LC, Boylan GB, Broadhurst DI, Murray DM.

Neonatology. 2016;110(4):296-302. Epub 2016 Aug 3.


Lipid mediator profile in vernix caseosa reflects skin barrier development.

Checa A, Holm T, Sjödin MO, Reinke SN, Alm J, Scheynius A, Wheelock CE.

Sci Rep. 2015 Nov 2;5:15740. doi: 10.1038/srep15740.


The effect of haemolysis on the metabolomic profile of umbilical cord blood.

Denihan NM, Walsh BH, Reinke SN, Sykes BD, Mandal R, Wishart DS, Broadhurst DI, Boylan GB, Murray DM.

Clin Biochem. 2015 May;48(7-8):534-7. doi: 10.1016/j.clinbiochem.2015.02.004. Epub 2015 Feb 16.


Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS.

Walsh JG, Reinke SN, Mamik MK, McKenzie BA, Maingat F, Branton WG, Broadhurst DI, Power C.

Retrovirology. 2014 May 13;11:35. doi: 10.1186/1742-4690-11-35.


Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis.

Reinke SN, Broadhurst DL, Sykes BD, Baker GB, Catz I, Warren KG, Power C.

Mult Scler. 2014 Sep;20(10):1396-400. doi: 10.1177/1352458513516528. Epub 2014 Jan 27.


1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy.

Reinke SN, Walsh BH, Boylan GB, Sykes BD, Kenny LC, Murray DM, Broadhurst DI.

J Proteome Res. 2013 Sep 6;12(9):4230-9. doi: 10.1021/pr400617m. Epub 2013 Aug 21.


Moving metabolomics from a data-driven science to an integrative systems science.

Reinke SN, Broadhurst DI.

Genome Med. 2012 Nov 15;4(11):85. doi: 10.1186/gm386. eCollection 2012.


Metagenomic and metabolomic characterization of rabies encephalitis: new insights into the treatment of an ancient disease.

Reinke SN, Resch L, Maingat F, Branton W, Jackson AC, Holt R, Slupsky C, Marrie T, Sykes BD, Power C.

J Infect Dis. 2013 May 1;207(9):1451-6. doi: 10.1093/infdis/jis479. Epub 2012 Aug 21.


Expression of Saccharomyces cerevisiae Sdh3p and Sdh4p paralogs results in catalytically active succinate dehydrogenase isoenzymes.

Szeto SS, Reinke SN, Oyedotun KS, Sykes BD, Lemire BD.

J Biol Chem. 2012 Jun 29;287(27):22509-20. doi: 10.1074/jbc.M112.344275. Epub 2012 May 9.


Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.

Lamarre SG, Molloy AM, Reinke SN, Sykes BD, Brosnan ME, Brosnan JT.

Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E61-7. doi: 10.1152/ajpendo.00345.2011. Epub 2011 Sep 20.


(1)H NMR-based metabolic profiling reveals inherent biological variation in yeast and nematode model systems.

Szeto SS, Reinke SN, Lemire BD.

J Biomol NMR. 2011 Apr;49(3-4):245-54. doi: 10.1007/s10858-011-9492-6. Epub 2011 Feb 25.


Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting.

Szeto SS, Reinke SN, Sykes BD, Lemire BD.

J Proteome Res. 2010 Dec 3;9(12):6729-39. doi: 10.1021/pr100880y. Epub 2010 Nov 5.


Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size.

Reinke SN, Hu X, Sykes BD, Lemire BD.

Mol Genet Metab. 2010 Jul;100(3):274-82. doi: 10.1016/j.ymgme.2010.03.013. Epub 2010 Mar 20.


A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA.

Friis RM, Wu BP, Reinke SN, Hockman DJ, Sykes BD, Schultz MC.

Nucleic Acids Res. 2009 Jul;37(12):3969-80. doi: 10.1093/nar/gkp270. Epub 2009 Apr 30.


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