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Items: 30

1.

Ocular intracameral pharmacokinetics for a cocktail of timolol, betaxolol and atenolol in rabbits.

Fayyaz A, Ranta VP, Toropainen E, Vellonen KS, Ricci GD, Reinisalo M, Heikkinen EM, Gardner I, Urtti A, Jamei M, Del Amo EM.

Mol Pharm. 2019 Dec 3. doi: 10.1021/acs.molpharmaceut.9b01024. [Epub ahead of print]

PMID:
31794668
2.

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

Hellinen L, Sato K, Reinisalo M, Kidron H, Rilla K, Tachikawa M, Uchida Y, Terasaki T, Urtti A.

Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):5022-5034. doi: 10.1167/iovs.19-27328.

PMID:
31791063
3.

The Basis for Strain-Dependent Rat Aldehyde Dehydrogenase 1A7 (ALDH1A7) Gene Expression.

Touloupi K, Küblbeck J, Magklara A, Molnár F, Reinisalo M, Konstandi M, Honkakoski P, Pappas P.

Mol Pharmacol. 2019 Nov;96(5):655-663. doi: 10.1124/mol.119.117424. Epub 2019 Oct 1.

PMID:
31575620
4.

Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model.

Hellinen L, Hagström M, Knuutila H, Ruponen M, Urtti A, Reinisalo M.

Sci Rep. 2019 Sep 24;9(1):13761. doi: 10.1038/s41598-019-50324-8.

5.

Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties.

Hellinen L, Pirskanen L, Tengvall-Unadike U, Urtti A, Reinisalo M.

Pharmaceutics. 2019 Aug 13;11(8). pii: E412. doi: 10.3390/pharmaceutics11080412.

6.

Nucleic acid delivery to differentiated retinal pigment epithelial cells using cell-penetrating peptide as a carrier.

Subia B, Reinisalo M, Dey N, Tavakoli S, Subrizi A, Ganguli M, Ruponen M.

Eur J Pharm Biopharm. 2019 Jul;140:91-99. doi: 10.1016/j.ejpb.2019.05.003. Epub 2019 May 11.

PMID:
31085311
7.

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.

Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.

Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14.

8.

Implications of melanin binding in ocular drug delivery.

Rimpelä AK, Reinisalo M, Hellinen L, Grazhdankin E, Kidron H, Urtti A, Del Amo EM.

Adv Drug Deliv Rev. 2018 Feb 15;126:23-43. doi: 10.1016/j.addr.2017.12.008. Epub 2017 Dec 13. Review.

PMID:
29247767
9.

Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts.

Pelkonen L, Tengvall-Unadike U, Ruponen M, Kidron H, Del Amo EM, Reinisalo M, Urtti A.

Eur J Pharm Sci. 2017 Nov 15;109:162-168. doi: 10.1016/j.ejps.2017.07.027. Epub 2017 Jul 27.

PMID:
28756205
10.

Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.

Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen JMT, Reinisalo M, Koistinen A, Uusitalo H, Sinha D, Skottman H, Kaarniranta K.

Int J Mol Sci. 2017 May 19;18(5). pii: E1089. doi: 10.3390/ijms18051089.

11.

LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.

Pelkonen L, Sato K, Reinisalo M, Kidron H, Tachikawa M, Watanabe M, Uchida Y, Urtti A, Terasaki T.

Mol Pharm. 2017 Mar 6;14(3):605-613. doi: 10.1021/acs.molpharmaceut.6b00782. Epub 2017 Feb 14.

PMID:
28112518
12.

Pharmacokinetic aspects of retinal drug delivery.

Del Amo EM, Rimpelä AK, Heikkinen E, Kari OK, Ramsay E, Lajunen T, Schmitt M, Pelkonen L, Bhattacharya M, Richardson D, Subrizi A, Turunen T, Reinisalo M, Itkonen J, Toropainen E, Casteleijn M, Kidron H, Antopolsky M, Vellonen KS, Ruponen M, Urtti A.

Prog Retin Eye Res. 2017 Mar;57:134-185. doi: 10.1016/j.preteyeres.2016.12.001. Epub 2016 Dec 24. Review.

13.

Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium.

Pelkonen L, Reinisalo M, Morin-Picardat E, Kidron H, Urtti A.

PLoS One. 2016 Aug 23;11(8):e0160352. doi: 10.1371/journal.pone.0160352. eCollection 2016.

14.

Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells.

Hakkarainen JJ, Reinisalo M, Ragauskas S, Seppänen A, Kaja S, Kalesnykas G.

Int J Pharm. 2016 Sep 10;511(1):73-78. doi: 10.1016/j.ijpharm.2016.06.135. Epub 2016 Jun 29.

PMID:
27374205
15.

Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells.

Koskela A, Reinisalo M, Petrovski G, Sinha D, Olmiere C, Karjalainen R, Kaarniranta K.

Nutrients. 2016 May 11;8(5). pii: E284. doi: 10.3390/nu8050284.

16.

Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases.

Reinisalo M, Kårlund A, Koskela A, Kaarniranta K, Karjalainen RO.

Oxid Med Cell Longev. 2015;2015:340520. doi: 10.1155/2015/340520. Epub 2015 Jun 9. Review.

17.

Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells.

Koskela A, Reinisalo M, Hyttinen JM, Kaarniranta K, Karjalainen RO.

Mol Vis. 2014 Jun 2;20:760-9. eCollection 2014.

19.

Filter-cultured ARPE-19 cells as outer blood-retinal barrier model.

Mannermaa E, Reinisalo M, Ranta VP, Vellonen KS, Kokki H, Saarikko A, Kaarniranta K, Urtti A.

Eur J Pharm Sci. 2010 Jul 11;40(4):289-96. doi: 10.1016/j.ejps.2010.04.001. Epub 2010 Apr 10.

PMID:
20385230
20.

Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.

Küblbeck J, Reinisalo M, Mustonen R, Honkakoski P.

Eur J Pharm Sci. 2010 Jul 11;40(4):263-72. doi: 10.1016/j.ejps.2010.03.022. Epub 2010 Apr 8.

PMID:
20381613
21.

Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection.

Ruponen M, Arkko S, Urtti A, Reinisalo M, Ranta VP.

J Control Release. 2009 Jun 19;136(3):226-31. doi: 10.1016/j.jconrel.2009.02.012. Epub 2009 Feb 26.

PMID:
19249330
22.

Microarray analysis of the global alterations in the gene expression in the placentas from cigarette-smoking mothers.

Huuskonen P, Storvik M, Reinisalo M, Honkakoski P, Rysä J, Hakkola J, Pasanen M.

Clin Pharmacol Ther. 2008 Apr;83(4):542-50. Epub 2007 Oct 27.

PMID:
17928820
23.

Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans.

Männistö M, Reinisalo M, Ruponen M, Honkakoski P, Tammi M, Urtti A.

J Gene Med. 2007 Jun;9(6):479-87.

PMID:
17410614
24.

Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells.

Reinisalo M, Urtti A, Honkakoski P.

J Control Release. 2006 Jan 10;110(2):437-443. doi: 10.1016/j.jconrel.2005.10.003. Epub 2005 Nov 16.

PMID:
16297485
25.

Absorption properties and P-glycoprotein activity of modified Caco-2 cell lines.

Korjamo T, Honkakoski P, Toppinen MR, Niva S, Reinisalo M, Palmgrén JJ, Mönkkönen J.

Eur J Pharm Sci. 2005 Nov;26(3-4):266-79.

PMID:
16111871
26.

Long-lasting secretion of transgene product from differentiated and filter-grown retinal pigment epithelial cells after nonviral gene transfer.

Mannermaa E, Rönkkö S, Ruponen M, Reinisalo M, Urtti A.

Curr Eye Res. 2005 May;30(5):345-53.

PMID:
16020265
27.

Dual action of oestrogens on the mouse constitutive androstane receptor.

Mäkinen J, Reinisalo M, Niemi K, Viitala P, Jyrkkärinne J, Chung H, Pelkonen O, Honkakoski P.

Biochem J. 2003 Dec 1;376(Pt 2):465-72.

28.

Retina-specific gene expression and improved DNA transfection in WERI-Rb1 retinoblastoma cells.

Reinisalo M, Urtti A, Honkakoski P.

Biochim Biophys Acta. 2003 Aug 25;1628(3):169-76.

PMID:
12932829
29.
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