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Items: 1 to 50 of 106

1.

Granulocyte transfusions - bridging to allogeneic hematopoietic stem cell transplantation.

Nguyen TM, Scholl K, Idler I, Wais V, Körper S, Lotfi R, Bommer M, Wiesneth M, Schrezenmeier H, Döhner H, Bohl SR, Harsdorf SV, Reinhardt P, Bunjes D, Ringhoffer M, Kuchenbauer F.

Leuk Lymphoma. 2020 Feb;61(2):481-484. doi: 10.1080/10428194.2019.1660977. Epub 2019 Sep 24. No abstract available.

PMID:
31547738
2.

Generating Human iPSC-Derived Astrocytes with Chemically Defined Medium for In Vitro Disease Modeling.

Janssen K, Bahnassawy L, Kiefer C, Korffmann J, Terstappen GC, Lakics V, Cik M, Reinhardt P.

Methods Mol Biol. 2019;1994:31-39. doi: 10.1007/978-1-4939-9477-9_3.

PMID:
31124102
3.

Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.

Bursch F, Kalmbach N, Naujock M, Staege S, Eggenschwiler R, Abo-Rady M, Japtok J, Guo W, Hensel N, Reinhardt P, Boeckers TM, Cantz T, Sterneckert J, Van Den Bosch L, Hermann A, Petri S, Wegner F.

Hum Mol Genet. 2019 Sep 1;28(17):2835-2850. doi: 10.1093/hmg/ddz107.

PMID:
31108504
4.

Quantum Package 2.0: An Open-Source Determinant-Driven Suite of Programs.

Garniron Y, Applencourt T, Gasperich K, Benali A, Ferté A, Paquier J, Pradines B, Assaraf R, Reinhardt P, Toulouse J, Barbaresco P, Renon N, David G, Malrieu JP, Véril M, Caffarel M, Loos PF, Giner E, Scemama A.

J Chem Theory Comput. 2019 Jun 11;15(6):3591-3609. doi: 10.1021/acs.jctc.9b00176. Epub 2019 May 29.

PMID:
31082265
5.

Modeling Parkinson's disease in midbrain-like organoids.

Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC.

NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019.

6.

Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.

Petros AM, Korepanova A, Jakob CG, Qiu W, Panchal SC, Wang J, Dietrich JD, Brewer JT, Pohlki F, Kling A, Wilcox K, Lakics V, Bahnassawy L, Reinhardt P, Partha SK, Bodelle PM, Lake M, Charych EI, Stoll VS, Sun C, Mohler EG.

J Med Chem. 2019 Apr 25;62(8):4120-4130. doi: 10.1021/acs.jmedchem.9b00178. Epub 2019 Apr 12.

PMID:
30933499
7.

Gender, cholinesterase, platelet count and red cell count are main predictors of peripheral blood stem cell mobilization in healthy donors.

Fürst D, Hauber D, Reinhardt P, Schauwecker P, Bunjes D, Schulz A, Mytilineos J, Wiesneth M, Schrezenmeier H, Körper S.

Vox Sang. 2019 Apr;114(3):275-282. doi: 10.1111/vox.12754. Epub 2019 Mar 14.

PMID:
30873634
8.

Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo.

Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, Sterneckert JL.

Stem Cell Reports. 2019 Mar 5;12(3):502-517. doi: 10.1016/j.stemcr.2019.01.015. Epub 2019 Feb 14.

9.

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study.

Volpato V, Smith J, Sandor C, Ried JS, Baud A, Handel A, Newey SE, Wessely F, Attar M, Whiteley E, Chintawar S, Verheyen A, Barta T, Lako M, Armstrong L, Muschet C, Artati A, Cusulin C, Christensen K, Patsch C, Sharma E, Nicod J, Brownjohn P, Stubbs V, Heywood WE, Gissen P, De Filippis R, Janssen K, Reinhardt P, Adamski J, Royaux I, Peeters PJ, Terstappen GC, Graf M, Livesey FJ, Akerman CJ, Mills K, Bowden R, Nicholson G, Webber C, Cader MZ, Lakics V.

Stem Cell Reports. 2018 Oct 9;11(4):897-911. doi: 10.1016/j.stemcr.2018.08.013. Epub 2018 Sep 20.

10.

Defective mitochondrial and lysosomal trafficking in chorea-acanthocytosis is independent of Src-kinase signaling.

Glaß H, Pal A, Reinhardt P, Sterneckert J, Wegner F, Storch A, Hermann A.

Mol Cell Neurosci. 2018 Oct;92:137-148. doi: 10.1016/j.mcn.2018.08.002. Epub 2018 Aug 3.

PMID:
30081151
11.

Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation.

Kreiter N, Pal A, Lojewski X, Corcia P, Naujock M, Reinhardt P, Sterneckert J, Petri S, Wegner F, Storch A, Hermann A.

Neurobiol Dis. 2018 Jul;115:167-181. doi: 10.1016/j.nbd.2018.03.010. Epub 2018 Apr 6.

PMID:
29630989
12.

Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease.

Marrone L, Bus C, Schöndorf D, Fitzgerald JC, Kübler M, Schmid B, Reinhardt P, Reinhardt L, Deleidi M, Levin T, Meixner A, Klink B, Glatza M, Gloeckner CJ, Gasser T, Sterneckert J.

PLoS One. 2018 Mar 7;13(3):e0192497. doi: 10.1371/journal.pone.0192497. eCollection 2018.

13.

Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.

Höing S, Yeh TY, Baumann M, Martinez NE, Habenberger P, Kremer L, Drexler HCA, Küchler P, Reinhardt P, Choidas A, Zischinsky ML, Zischinsky G, Nandini S, Ledray AP, Ketcham SA, Reinhardt L, Abo-Rady M, Glatza M, King SJ, Nussbaumer P, Ziegler S, Klebl B, Schroer TA, Schöler HR, Waldmann H, Sterneckert J.

Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6. doi: 10.1016/j.chembiol.2017.12.014. Epub 2018 Jan 27.

14.

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.

Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A.

Nat Commun. 2018 Jan 23;9(1):335. doi: 10.1038/s41467-017-02299-1.

15.

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.

Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL.

Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18.

16.

A validated antibody panel for the characterization of tau post-translational modifications.

Ercan E, Eid S, Weber C, Kowalski A, Bichmann M, Behrendt A, Matthes F, Krauss S, Reinhardt P, Fulle S, Ehrnhoefer DE.

Mol Neurodegener. 2017 Nov 21;12(1):87. doi: 10.1186/s13024-017-0229-1.

17.

The Wilms tumor protein Wt1 contributes to female fertility by regulating oviductal proteostasis.

Nathan A, Reinhardt P, Kruspe D, Jörß T, Groth M, Nolte H, Habenicht A, Herrmann J, Holschbach V, Toth B, Krüger M, Wang ZQ, Platzer M, Englert C.

Hum Mol Genet. 2017 May 1;26(9):1694-1705. doi: 10.1093/hmg/ddx075.

18.

Hydrogen isotope fractionation in methane plasma.

Robert F, Derenne S, Lombardi G, Hassouni K, Michau A, Reinhardt P, Duhamel R, Gonzalez A, Biron K.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):870-874. doi: 10.1073/pnas.1615767114. Epub 2017 Jan 17.

19.

Neuronal Dysfunction in iPSC-Derived Medium Spiny Neurons from Chorea-Acanthocytosis Patients Is Reversed by Src Kinase Inhibition and F-Actin Stabilization.

Stanslowsky N, Reinhardt P, Glass H, Kalmbach N, Naujock M, Hensel N, Lübben V, Pal A, Venneri A, Lupo F, De Franceschi L, Claus P, Sterneckert J, Storch A, Hermann A, Wegner F.

J Neurosci. 2016 Nov 23;36(47):12027-12043.

20.

Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells.

Speidel A, Felk S, Reinhardt P, Sterneckert J, Gillardon F.

PLoS One. 2016 Nov 3;11(11):e0165949. doi: 10.1371/journal.pone.0165949. eCollection 2016.

21.

Healthy donor hematopoietic stem cell mobilization with biosimilar granulocyte-colony-stimulating factor: safety, efficacy, and graft performance.

Becker P, Schwebig A, Brauninger S, Bialleck H, Luxembourg B, Schulz M, Tsamadou C, Wiesneth M, Reinhardt P, Mytilineos J, Seidl C, Gattu S, Kaliakina N, Singh P, Schrezenmeier H, Seifried E, Bonig H.

Transfusion. 2016 Dec;56(12):3055-3064. doi: 10.1111/trf.13853. Epub 2016 Sep 16.

PMID:
27633122
22.

Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors.

Hermann A, Kim JB, Srimasorn S, Zaehres H, Reinhardt P, Schöler HR, Storch A.

Stem Cells Int. 2016;2016:4736159. doi: 10.1155/2016/4736159. Epub 2016 Feb 9.

23.

4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.

Naujock M, Stanslowsky N, Bufler S, Naumann M, Reinhardt P, Sterneckert J, Kefalakes E, Kassebaum C, Bursch F, Lojewski X, Storch A, Frickenhaus M, Boeckers TM, Putz S, Demestre M, Liebau S, Klingenstein M, Ludolph AC, Dengler R, Kim KS, Hermann A, Wegner F, Petri S.

Stem Cells. 2016 Jun;34(6):1563-75. doi: 10.1002/stem.2354. Epub 2016 Mar 28.

24.

Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.

Japtok J, Lojewski X, Naumann M, Klingenstein M, Reinhardt P, Sterneckert J, Putz S, Demestre M, Boeckers TM, Ludolph AC, Liebau S, Storch A, Hermann A.

Neurobiol Dis. 2015 Oct;82:420-429. doi: 10.1016/j.nbd.2015.07.017. Epub 2015 Aug 4.

PMID:
26253605
25.

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.

Ehrlich M, Hallmann AL, Reinhardt P, Araúzo-Bravo MJ, Korr S, Röpke A, Psathaki OE, Ehling P, Meuth SG, Oblak AL, Murrell JR, Ghetti B, Zaehres H, Schöler HR, Sterneckert J, Kuhlmann T, Hargus G.

Stem Cell Reports. 2015 Jul 14;5(1):83-96. doi: 10.1016/j.stemcr.2015.06.001. Epub 2015 Jul 2.

26.

Erratum: "Spin-unrestricted random-phase approximation with range separation: Benchmark on atomization energies and reaction barrier heights" [J. Chem. Phys. 142, 154123 (2015)].

Mussard B, Reinhardt P, Ángyán JG, Toulouse J.

J Chem Phys. 2015 Jun 7;142(21):219901. doi: 10.1063/1.4921987. No abstract available.

PMID:
26049531
27.

Spin-unrestricted random-phase approximation with range separation: Benchmark on atomization energies and reaction barrier heights.

Mussard B, Reinhardt P, Ángyán JG, Toulouse J.

J Chem Phys. 2015 Apr 21;142(15):154123. doi: 10.1063/1.4918710. Erratum in: J Chem Phys. 2015 Jun 7;142(21):219901.

PMID:
25903882
28.

Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.

Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H.

Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15.

29.

iPS cell derived neuronal cells for drug discovery.

Heilker R, Traub S, Reinhardt P, Schöler HR, Sterneckert J.

Trends Pharmacol Sci. 2014 Oct;35(10):510-9. doi: 10.1016/j.tips.2014.07.003. Epub 2014 Aug 3. Review.

PMID:
25096281
30.

Investigating human disease using stem cell models.

Sterneckert JL, Reinhardt P, Schöler HR.

Nat Rev Genet. 2014 Sep;15(9):625-39. doi: 10.1038/nrg3764. Epub 2014 Jul 29. Review.

PMID:
25069490
31.

Molecular and functional analyses of motor neurons generated from human cord-blood-derived induced pluripotent stem cells.

Naujock M, Stanslowsky N, Reinhardt P, Sterneckert J, Haase A, Martin U, Kim KS, Dengler R, Wegner F, Petri S.

Stem Cells Dev. 2014 Dec 15;23(24):3011-20. doi: 10.1089/scd.2014.0180.

PMID:
25007389
32.

A combined experimental and theoretical study of the Ti2 + N2O reaction.

Marzouk A, Bolvin H, Reinhardt P, Manceron L, Perchard JP, Tremblay B, Alikhani ME.

J Phys Chem A. 2014 Jan 23;118(3):561-72. doi: 10.1021/jp406479n. Epub 2014 Jan 10.

PMID:
24383464
33.

Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.

Lojewski X, Staropoli JF, Biswas-Legrand S, Simas AM, Haliw L, Selig MK, Coppel SH, Goss KA, Petcherski A, Chandrachud U, Sheridan SD, Lucente D, Sims KB, Gusella JF, Sondhi D, Crystal RG, Reinhardt P, Sterneckert J, Schöler H, Haggarty SJ, Storch A, Hermann A, Cotman SL.

Hum Mol Genet. 2014 Apr 15;23(8):2005-22. doi: 10.1093/hmg/ddt596. Epub 2013 Nov 23.

34.

Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.

Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J.

PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/6a917a2e-df4a-4ad9-99bb-6aa7218b833e.

35.

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.

Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J.

Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008.

36.

Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins.

Tapia N, Reinhardt P, Duemmler A, Wu G, Araúzo-Bravo MJ, Esch D, Greber B, Cojocaru V, Rascon CA, Tazaki A, Kump K, Voss R, Tanaka EM, Schöler HR.

Nat Commun. 2012;3:1279. doi: 10.1038/ncomms2229. Erratum in: Nat Commun. 2013;4:1460.

37.

Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay.

Höing S, Rudhard Y, Reinhardt P, Glatza M, Stehling M, Wu G, Peiker C, Böcker A, Parga JA, Bunk E, Schwamborn JC, Slack M, Sterneckert J, Schöler HR.

Cell Stem Cell. 2012 Nov 2;11(5):620-32. doi: 10.1016/j.stem.2012.07.005. Epub 2012 Oct 11.

38.

Zfp296 is a novel, pluripotent-specific reprogramming factor.

Fischedick G, Klein DC, Wu G, Esch D, Höing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Schöler HR, Sterneckert JL.

PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2.

39.

Brief report: evaluating the potential of putative pluripotent cells derived from human testis.

Ko K, Reinhardt P, Tapia N, Schneider RK, Araúzo-Bravo MJ, Han DW, Greber B, Kim J, Kliesch S, Zenke M, Schöler HR.

Stem Cells. 2011 Aug;29(8):1304-9. doi: 10.1002/stem.671.

40.

Automatic interface-controlled apheresis collection of stem/progenitor cells: results from an autologous donor validation trial of a novel stem cell apheresis device.

Reinhardt P, Brauninger S, Bialleck H, Thorausch K, Smith R, Schrezenmeier H, Seifried E, Wiesneth M, Bonig H.

Transfusion. 2011 Jun;51(6):1321-30. doi: 10.1111/j.1537-2995.2010.02992.x. Epub 2010 Dec 13.

PMID:
21155834
41.

Polarizable molecular dynamics simulation of Zn(II) in water using the AMOEBA force field.

Wu JC, Piquemal JP, Chaudret R, Reinhardt P, Ren P.

J Chem Theory Comput. 2010 Jul 13;6(7):2059-2070.

42.

Evidence of children's vulnerability to radiation in the context of radiological/nuclear events and considerations for emergency response.

Lane R, Reinhardt P, Thompson P.

Radiat Prot Dosimetry. 2010 Nov;142(1):36-9. doi: 10.1093/rpd/ncq272. Epub 2010 Oct 19.

PMID:
20959331
43.

Human adult germline stem cells in question.

Ko K, Araúzo-Bravo MJ, Tapia N, Kim J, Lin Q, Bernemann C, Han DW, Gentile L, Reinhardt P, Greber B, Schneider RK, Kliesch S, Zenke M, Schöler HR.

Nature. 2010 Jun 24;465(7301):E1; discussion E3. doi: 10.1038/nature09089.

PMID:
20577160
44.

Induction of pluripotency in human cord blood unrestricted somatic stem cells.

Zaehres H, Kögler G, Arauzo-Bravo MJ, Bleidissel M, Santourlidis S, Weinhold S, Greber B, Kim JB, Buchheiser A, Liedtke S, Eilken HM, Graffmann N, Zhao X, Meyer J, Reinhardt P, Burr B, Waclawczyk S, Ortmeier C, Uhrberg M, Schöler HR, Cantz T, Wernet P.

Exp Hematol. 2010 Sep;38(9):809-18, 818.e1-2. doi: 10.1016/j.exphem.2010.05.009. Epub 2010 Jun 10.

PMID:
20541586
45.

Preparation of granulocyte concentrates by apheresis.

Leitner G, Panzer S, Reesink HW, Stiegler G, Fischer-Nielsen A, Dickmeiss E, Einsele H, Reinhardt P, Schrezenmeier H, Wiesneth M, Coluccia P, Nygell UA, Halter J, Sigle J, Gratwohl A, Buser AS, Ozturk G, Anak S.

Vox Sang. 2010 May;98(4):567-75. doi: 10.1111/j.1423-0410.2010.01315.x. No abstract available.

PMID:
20529074
46.

Improved version of a local contracted configuration interaction of singles and doubles with partial inclusion of triples and quadruples.

Zhang H, Malrieu JP, Reinhardt P, Ma J.

J Chem Phys. 2010 Jan 21;132(3):034108. doi: 10.1063/1.3292605.

PMID:
20095729
47.

Fragment-Localized Kohn-Sham Orbitals via a Singles Configuration-Interaction Procedure and Application to Local Properties and Intermolecular Energy Decomposition Analysis.

Reinhardt P, Piquemal JP, Savin A.

J Chem Theory Comput. 2008 Dec 9;4(12):2020-9. doi: 10.1021/ct800242n. Epub 2008 Nov 5.

PMID:
26620475
48.

A local contracted treatment of single and double excitations.

Reinhardt P, Zhang H, Ma J, Malrieu JP.

J Chem Phys. 2008 Oct 28;129(16):164106. doi: 10.1063/1.2996126.

PMID:
19045246
49.

Evidence of an isomeric pair in furan...HCl: Fourier transform infrared spectroscopy and ab initio calculations.

Asselin P, Madebène B, Soulard P, Reinhardt P, Alikhani ME.

J Chem Phys. 2008 Jun 28;128(24):244301. doi: 10.1063/1.2944242.

PMID:
18601326
50.

Successful autologous peripheral blood stem cell transplantation in a Jehovah's Witness with multiple myeloma: review of literature and recommendations for high-dose chemotherapy without support of allogeneic blood products.

Schmitt S, Mailaender V, Egerer G, Leo A, Becker S, Reinhardt P, Wiesneth M, Schrezenmeier H, Ho AD, Goldschmidt H, Moehler TM.

Int J Hematol. 2008 Apr;87(3):289-97. doi: 10.1007/s12185-008-0055-x. Epub 2008 Mar 4. Review.

PMID:
18317881

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