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Items: 1 to 50 of 186

1.

IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization.

Castaño Z, San Juan BP, Spiegel A, Pant A, DeCristo MJ, Laszewski T, Ubellacker JM, Janssen SR, Dongre A, Reinhardt F, Henderson A, Del Rio AG, Gifford AM, Herbert ZT, Hutchinson JN, Weinberg RA, Chaffer CL, McAllister SS.

Nat Cell Biol. 2018 Sep;20(9):1084-1097. doi: 10.1038/s41556-018-0173-5. Epub 2018 Aug 27.

PMID:
30154549
2.

Epithelial-Mesenchymal Transition Induces Podocalyxin to Promote Extravasation via Ezrin Signaling.

Fröse J, Chen MB, Hebron KE, Reinhardt F, Hajal C, Zijlstra A, Kamm RD, Weinberg RA.

Cell Rep. 2018 Jul 24;24(4):962-972. doi: 10.1016/j.celrep.2018.06.092.

3.

Magnetic resonance imaging findings of high-grade ductal carcinoma in situ of the male breast: A case report.

Reinhardt F, Mathys B, Reinecke P, Neubauer H, Fehm T, Mohrmann S.

SAGE Open Med Case Rep. 2018 Jun 12;6:2050313X18781727. doi: 10.1177/2050313X18781727. eCollection 2018.

4.

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy.

Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA.

Sci Transl Med. 2018 Apr 11;10(436). pii: eaan3464. doi: 10.1126/scitranslmed.aan3464.

PMID:
29643230
5.

Seronegative alveolar echinococcosis in a patient with multiple myeloma.

Lübbert C, Reinhardt F, Karlas T, Schwarzer A, Riese F, Schmidt T, Bartels M.

Int J Infect Dis. 2018 Apr;69:47-49. doi: 10.1016/j.ijid.2018.02.001. Epub 2018 Feb 6. No abstract available.

6.

Navigation through inter- and intratumoral heterogeneity of endocrine resistance mechanisms in breast cancer: A potential role for Liquid Biopsies?

Reinhardt F, Franken A, Fehm T, Neubauer H.

Tumour Biol. 2017 Nov;39(11):1010428317731511. doi: 10.1177/1010428317731511. Review.

PMID:
29129161
7.

Phenotypic and genetic relationships between age at first calving, its component traits, and survival of heifers up to second calving.

Heise J, Stock KF, Reinhardt F, Ha NT, Simianer H.

J Dairy Sci. 2018 Jan;101(1):425-432. doi: 10.3168/jds.2017-12957. Epub 2017 Nov 8.

PMID:
29128222
8.

Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.

Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB.

Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y.

9.

Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.

Dongre A, Rashidian M, Reinhardt F, Bagnato A, Keckesova Z, Ploegh HL, Weinberg RA.

Cancer Res. 2017 Aug 1;77(15):3982-3989. doi: 10.1158/0008-5472.CAN-16-3292. Epub 2017 Apr 20.

10.

SMARCE1 is required for the invasive progression of in situ cancers.

Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4153-4158. doi: 10.1073/pnas.1703931114. Epub 2017 Apr 4.

11.

LACTB is a tumour suppressor that modulates lipid metabolism and cell state.

Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA.

Nature. 2017 Mar 30;543(7647):681-686. doi: 10.1038/nature21408. Epub 2017 Mar 22.

PMID:
28329758
12.

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells.

Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova Z, Weinberg RA.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2337-E2346. doi: 10.1073/pnas.1618298114. Epub 2017 Mar 7.

13.

Identification of a haplotype associated with cholesterol deficiency and increased juvenile mortality in Holstein cattle.

Kipp S, Segelke D, Schierenbeck S, Reinhardt F, Reents R, Wurmser C, Pausch H, Fries R, Thaller G, Tetens J, Pott J, Haas D, Raddatz BB, Hewicker-Trautwein M, Proios I, Schmicke M, Grünberg W.

J Dairy Sci. 2016 Nov;99(11):8915-8931. doi: 10.3168/jds.2016-11118. Epub 2016 Sep 7.

PMID:
27614835
14.

Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency.

De Cock JM, Shibue T, Dongre A, Keckesova Z, Reinhardt F, Weinberg RA.

Cancer Res. 2016 Dec 1;76(23):6778-6784. Epub 2016 Aug 16.

15.

Precise expression of Fis1 is important for glucose responsiveness of beta cells.

Schultz J, Waterstradt R, Kantowski T, Rickmann A, Reinhardt F, Sharoyko V, Mulder H, Tiedge M, Baltrusch S.

J Endocrinol. 2016 Jul;230(1):81-91. doi: 10.1530/JOE-16-0111. Epub 2016 May 13.

PMID:
27179109
16.

Drp1 guarding of the mitochondrial network is important for glucose-stimulated insulin secretion in pancreatic beta cells.

Reinhardt F, Schultz J, Waterstradt R, Baltrusch S.

Biochem Biophys Res Commun. 2016 Jun 10;474(4):646-651. doi: 10.1016/j.bbrc.2016.04.142. Epub 2016 May 3.

PMID:
27154223
17.

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells.

Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA.

Cancer Discov. 2016 Jun;6(6):630-49. doi: 10.1158/2159-8290.CD-15-1157. Epub 2016 Apr 12.

18.

AMPK promotes tolerance to Ras pathway inhibition by activating autophagy.

Sanduja S, Feng Y, Mathis RA, Sokol ES, Reinhardt F, Halaban R, Gupta PB.

Oncogene. 2016 Oct 6;35(40):5295-5303. doi: 10.1038/onc.2016.70. Epub 2016 Apr 4.

19.

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability.

Pattabiraman DR, Bierie B, Kober KI, Thiru P, Krall JA, Zill C, Reinhardt F, Tam WL, Weinberg RA.

Science. 2016 Mar 4;351(6277):aad3680. doi: 10.1126/science.aad3680.

20.

Technical note: Equivalent genomic models with a residual polygenic effect.

Liu Z, Goddard ME, Hayes BJ, Reinhardt F, Reents R.

J Dairy Sci. 2016 Mar;99(3):2016-2025. doi: 10.3168/jds.2015-10394. Epub 2015 Dec 24.

PMID:
26723117
21.

The genetic structure of longevity in dairy cows.

Heise J, Liu Z, Stock KF, Rensing S, Reinhardt F, Simianer H.

J Dairy Sci. 2016 Feb;99(2):1253-1265. doi: 10.3168/jds.2015-10163. Epub 2015 Nov 28.

PMID:
26627862
22.

Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.

Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA.

Nat Cell Biol. 2015 Dec;17(12):1607. doi: 10.1038/ncb3281. No abstract available.

PMID:
26612575
23.

Considering genetic characteristics in German Holstein breeding programs.

Segelke D, Täubert H, Reinhardt F, Thaller G.

J Dairy Sci. 2016 Jan;99(1):458-67. doi: 10.3168/jds.2015-9764. Epub 2015 Nov 18.

PMID:
26601581
24.

A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial-onset seizures in daily clinical practice: The VITOBA study.

Runge U, Arnold S, Brandt C, Reinhardt F, Kühn F, Isensee K, Ramirez F, Dedeken P, Lauterbach T, Noack-Rink M, Mayer T.

Epilepsia. 2015 Dec;56(12):1921-30. doi: 10.1111/epi.13224. Epub 2015 Nov 3.

25.

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.

Ye X, Tam WL, Shibue T, Kaygusuz Y, Reinhardt F, Ng Eaton E, Weinberg RA.

Nature. 2015 Sep 10;525(7568):256-60. doi: 10.1038/nature14897. Epub 2015 Sep 2.

26.

Short communication: Validation of 4 candidate causative trait variants in 2 cattle breeds using targeted sequence imputation.

Pausch H, Wurmser C, Reinhardt F, Emmerling R, Fries R.

J Dairy Sci. 2015 Jun;98(6):4162-7. doi: 10.3168/jds.2015-9402. Epub 2015 Apr 16.

PMID:
25892690
27.

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.

Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA.

Nat Cell Biol. 2014 Nov;16(11):1105-17. doi: 10.1038/ncb3041. Epub 2014 Sep 28. Erratum in: Nat Cell Biol. 2015 Dec;17(12):1607.

28.

De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling.

Del Vecchio CA, Feng Y, Sokol ES, Tillman EJ, Sanduja S, Reinhardt F, Gupta PB.

PLoS Biol. 2014 Sep 9;12(9):e1001945. doi: 10.1371/journal.pbio.1001945. eCollection 2014 Sep.

29.

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.

Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM.

Cell. 2014 Aug 28;158(5):1094-1109. doi: 10.1016/j.cell.2014.07.032.

30.

A single-step genomic model with direct estimation of marker effects.

Liu Z, Goddard ME, Reinhardt F, Reents R.

J Dairy Sci. 2014 Sep;97(9):5833-50. doi: 10.3168/jds.2014-7924. Epub 2014 Jul 11.

31.

Prediction of expected genetic variation within groups of offspring for innovative mating schemes.

Segelke D, Reinhardt F, Liu Z, Thaller G.

Genet Sel Evol. 2014 Jul 2;46:42. doi: 10.1186/1297-9686-46-42.

32.

Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer.

Luo ML, Gong C, Chen CH, Lee DY, Hu H, Huang P, Yao Y, Guo W, Reinhardt F, Wulf G, Lieberman J, Zhou XZ, Song E, Lu KP.

Cancer Res. 2014 Jul 1;74(13):3603-16. doi: 10.1158/0008-5472.CAN-13-2785. Epub 2014 May 1.

33.

Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress.

Feng YX, Sokol ES, Del Vecchio CA, Sanduja S, Claessen JH, Proia TA, Jin DX, Reinhardt F, Ploegh HL, Wang Q, Gupta PB.

Cancer Discov. 2014 Jun;4(6):702-15. doi: 10.1158/2159-8290.CD-13-0945. Epub 2014 Apr 4.

34.

Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.

Merritt MA, Bentink S, Schwede M, Iwanicki MP, Quackenbush J, Woo T, Agoston ES, Reinhardt F, Crum CP, Berkowitz RS, Mok SC, Witt AE, Jones MA, Wang B, Ince TA.

PLoS One. 2013 Nov 26;8(11):e80314. doi: 10.1371/journal.pone.0080314. eCollection 2013.

35.

Genome-wide association analysis to identify genotype × environment interaction for milk protein yield and level of somatic cell score as environmental descriptors in German Holsteins.

Streit M, Reinhardt F, Thaller G, Bennewitz J.

J Dairy Sci. 2013;96(11):7318-24. doi: 10.3168/jds.2013-7133. Epub 2013 Sep 18.

PMID:
24054293
36.

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells.

Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA.

Cancer Cell. 2013 Sep 9;24(3):347-64. doi: 10.1016/j.ccr.2013.08.005.

37.

Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity.

Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, D'Alessio AC, Young RA, Weinberg RA.

Cell. 2013 Jul 3;154(1):61-74. doi: 10.1016/j.cell.2013.06.005.

38.

Using genome-wide association analysis to characterize environmental sensitivity of milk traits in dairy cattle.

Streit M, Wellmann R, Reinhardt F, Thaller G, Piepho HP, Bennewitz J.

G3 (Bethesda). 2013 Jul 8;3(7):1085-93. doi: 10.1534/g3.113.006536.

39.

A novel instrument for quantitative nanoanalytics involving complementary X-ray methodologies.

Lubeck J, Beckhoff B, Fliegauf R, Holfelder I, Hönicke P, Müller M, Pollakowski B, Reinhardt F, Weser J.

Rev Sci Instrum. 2013 Apr;84(4):045106. doi: 10.1063/1.4798299.

PMID:
23635231
40.

Novel use of derived genotype probabilities to discover significant dominance effects for milk production traits in dairy cattle.

Boysen TJ, Heuer C, Tetens J, Reinhardt F, Thaller G.

Genetics. 2013 Feb;193(2):431-42. doi: 10.1534/genetics.112.144535. Epub 2012 Dec 5.

41.

Reaction norms and genotype-by-environment interaction in the German Holstein dairy cattle.

Streit M, Reinhardt F, Thaller G, Bennewitz J.

J Anim Breed Genet. 2012 Oct;129(5):380-9. doi: 10.1111/j.1439-0388.2012.00999.x. Epub 2012 Apr 28.

PMID:
22963359
42.

Reliability of genomic prediction for German Holsteins using imputed genotypes from low-density chips.

Segelke D, Chen J, Liu Z, Reinhardt F, Thaller G, Reents R.

J Dairy Sci. 2012 Sep;95(9):5403-5411. doi: 10.3168/jds.2012-5466.

PMID:
22916947
43.

Identification and dissection of four major QTL affecting milk fat content in the German Holstein-Friesian population.

Wang X, Wurmser C, Pausch H, Jung S, Reinhardt F, Tetens J, Thaller G, Fries R.

PLoS One. 2012;7(7):e40711. doi: 10.1371/journal.pone.0040711. Epub 2012 Jul 11.

44.

Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling.

Li HJ, Reinhardt F, Herschman HR, Weinberg RA.

Cancer Discov. 2012 Sep;2(9):840-55. doi: 10.1158/2159-8290.CD-12-0101. Epub 2012 Jul 3.

45.

The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions.

Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA.

Cancer Discov. 2012 Aug;2(8):706-21. doi: 10.1158/2159-8290.CD-11-0239. Epub 2012 May 18.

46.

Slug and Sox9 cooperatively determine the mammary stem cell state.

Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA.

Cell. 2012 Mar 2;148(5):1015-28. doi: 10.1016/j.cell.2012.02.008.

47.

Controlling inbreeding and maximizing genetic gain using semi-definite programming with pedigree-based and genomic relationships.

Schierenbeck S, Pimentel EC, Tietze M, Körte J, Reents R, Reinhardt F, Simianer H, König S.

J Dairy Sci. 2011 Dec;94(12):6143-52. doi: 10.3168/jds.2011-4574.

PMID:
22118102
48.

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.

Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA.

Cell. 2011 Jun 10;145(6):926-40. doi: 10.1016/j.cell.2011.04.029.

49.

Impacts of both reference population size and inclusion of a residual polygenic effect on the accuracy of genomic prediction.

Liu Z, Seefried FR, Reinhardt F, Rensing S, Thaller G, Reents R.

Genet Sel Evol. 2011 May 17;43:19. doi: 10.1186/1297-9686-43-19.

50.

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.

Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7950-5. doi: 10.1073/pnas.1102454108. Epub 2011 Apr 15.

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