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Items: 1 to 50 of 116

1.

Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models.

Donabedian PL, Kossatz S, Engelbach JA, Jannetti SA, Carney B, Young RJ, Weber WA, Garbow JR, Reiner T.

EJNMMI Res. 2018 Jul 4;8(1):59. doi: 10.1186/s13550-018-0399-z.

PMID:
29974335
2.

Antibody with infinite affinity for in vivo tracking of genetically engineered lymphocytes.

Krebs S, Ahad A, Carter L, Eyquem J, Brand C, Bell M, Ponomarev V, Reiner T, Meares CF, Gottschalk S, Sadelain M, Larson SM, Weber WA.

J Nucl Med. 2018 Jun 14. pii: jnumed.118.208041. doi: 10.2967/jnumed.118.208041. [Epub ahead of print]

PMID:
29903928
3.

The influence of the twin peg design on femoral Interface temperature and maximum load to failure in cemented Oxford unicompartmental knee arthroplasty.

Reiner T, Schwarze M, Panzram B, Klotz MC, Bitsch RG, Jaeger S.

Clin Biomech (Bristol, Avon). 2018 Jun;55:23-27. doi: 10.1016/j.clinbiomech.2018.04.003. Epub 2018 Apr 5.

PMID:
29649670
4.

Direct imaging of drug distribution and target engagement of the PARP inhibitor rucaparib.

Kossatz S, Carney B, Farley C, Drain CM, Weber WA, Reiner T.

J Nucl Med. 2018 Mar 23. pii: jnumed.117.205765. doi: 10.2967/jnumed.117.205765. [Epub ahead of print]

PMID:
29572258
5.

PARP1-Targeted Radiotherapy in Mouse Models of Glioblastoma.

Jannetti SA, Carlucci G, Carney B, Kossatz S, Shenker L, Carter LM, Salinas B, Brand C, Sadique A, Donabedian PL, Cunanan KM, Gönen M, Ponomarev V, Zeglis BM, Souweidane MM, Lewis JS, Weber WA, Humm JL, Reiner T.

J Nucl Med. 2018 Mar 23. pii: jnumed.117.205054. doi: 10.2967/jnumed.117.205054. [Epub ahead of print]

PMID:
29572254
6.

Reversible Electroporation-Mediated Liposomal Doxorubicin Delivery to Tumors Can Be Monitored With 89Zr-Labeled Reporter Nanoparticles.

Srimathveeravalli G, Abdel-Atti D, Pérez-Medina C, Takaki H, Solomon SB, Mulder WJM, Reiner T.

Mol Imaging. 2018 Jan-Dec;17:1536012117749726. doi: 10.1177/1536012117749726.

7.

Bioorthogonal Masking of Circulating Antibody-TCO Groups Using Tetrazine-Functionalized Dextran Polymers.

Meyer JP, Tully KM, Jackson J, Dilling TR, Reiner T, Lewis JS.

Bioconjug Chem. 2018 Feb 21;29(2):538-545. doi: 10.1021/acs.bioconjchem.8b00028. Epub 2018 Feb 9.

8.

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis.

Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S.

J Am Coll Cardiol. 2018 Jan 23;71(3):321-335. doi: 10.1016/j.jacc.2017.11.036.

9.

Cementless unicompartmental knee replacement allows early return to normal activity.

Panzram B, Bertlich I, Reiner T, Walker T, Hagmann S, Gotterbarm T.

BMC Musculoskelet Disord. 2018 Jan 17;19(1):18. doi: 10.1186/s12891-017-1883-8.

10.

Target engagement imaging of PARP inhibitors in small-cell lung cancer.

Carney B, Kossatz S, Lok BH, Schneeberger V, Gangangari KK, Pillarsetty NVK, Weber WA, Rudin CM, Poirier JT, Reiner T.

Nat Commun. 2018 Jan 12;9(1):176. doi: 10.1038/s41467-017-02096-w.

11.

Specific Binding of Liposomal Nanoparticles through Inverse Electron-Demand Diels-Alder Click Chemistry.

Brand C, Iacono P, Pérez-Medina C, Mulder WJM, Kircher MF, Reiner T.

ChemistryOpen. 2017 Aug 7;6(5):615-619. doi: 10.1002/open.201700105. eCollection 2017 Oct.

12.

Integrating nanomedicine and imaging.

Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM.

Philos Trans A Math Phys Eng Sci. 2017 Nov 28;375(2107). pii: 20170110. doi: 10.1098/rsta.2017.0110. Review.

PMID:
29038380
13.

MRI Findings in Patients After Small-Head Metal-on-Metal Total Hip Arthroplasty with a Minimum Follow-up of 10 Years.

Reiner T, Do TD, Klot MC, Hertzsch F, Seelmann K, Gaida MM, Weber MA, Gotterbarm T.

J Bone Joint Surg Am. 2017 Sep 20;99(18):1540-1546. doi: 10.2106/JBJS.16.01021.

PMID:
28926383
14.

Detection and Delineation of Oral Cancer With a PARP1-Targeted Optical Imaging Agent.

Kossatz S, Weber W, Reiner T.

Mol Imaging. 2017 Jan-Dec;16:1536012117723786. doi: 10.1177/1536012117723786.

15.

cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339.

Büchel GE, Kossatz S, Sadique A, Rapta P, Zalibera M, Bucinsky L, Komorovsky S, Telser J, Eppinger J, Reiner T, Arion VB.

Dalton Trans. 2017 Sep 12;46(35):11925-11941. doi: 10.1039/c7dt02194a.

PMID:
28850133
16.

Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.

Tang J, Salloum D, Carney B, Brand C, Kossatz S, Sadique A, Lewis JS, Weber WA, Wendel HG, Reiner T.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7441-E7449. doi: 10.1073/pnas.1705013114. Epub 2017 Aug 21.

17.

Synthesis of a Fluorescently Labeled 68Ga-DOTA-TOC Analog for Somatostatin Receptor Targeting.

Ghosh SC, Hernandez Vargas S, Rodriguez M, Kossatz S, Voss J, Carmon KS, Reiner T, Schonbrunn A, Azhdarinia A.

ACS Med Chem Lett. 2017 Jun 6;8(7):720-725. doi: 10.1021/acsmedchemlett.7b00125. eCollection 2017 Jul 13.

18.

A systematic comparison of clinically viable nanomedicines targeting HMG-CoA reductase in inflammatory atherosclerosis.

Alaarg A, Senders ML, Varela-Moreira A, Pérez-Medina C, Zhao Y, Tang J, Fay F, Reiner T, Fayad ZA, Hennink WE, Metselaar JM, Mulder WJM, Storm G.

J Control Release. 2017 Sep 28;262:47-57. doi: 10.1016/j.jconrel.2017.07.013. Epub 2017 Jul 9.

19.

Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.

Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R.

Nat Protoc. 2017 Jul;12(7):1472-1497. doi: 10.1038/nprot.2017.043. Epub 2017 Jun 29.

20.

Molecular Imaging of PARP.

Carney B, Kossatz S, Reiner T.

J Nucl Med. 2017 Jul;58(7):1025-1030. doi: 10.2967/jnumed.117.189936. Epub 2017 May 4. Review.

21.

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.

Beldman TJ, Senders ML, Alaarg A, Pérez-Medina C, Tang J, Zhao Y, Fay F, Deichmöller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E.

ACS Nano. 2017 Jun 27;11(6):5785-5799. doi: 10.1021/acsnano.7b01385. Epub 2017 May 15.

22.

Cementless Oxford medial unicompartimental knee replacement: an independent series with a 5-year-follow-up.

Panzram B, Bertlich I, Reiner T, Walker T, Hagmann S, Gotterbarm T.

Arch Orthop Trauma Surg. 2017 Jul;137(7):1011-1017. doi: 10.1007/s00402-017-2696-9. Epub 2017 Apr 24.

PMID:
28439705
23.

Sonophore labeled RGD: a targeted contrast agent for optoacoustic imaging.

Haedicke K, Brand C, Omar M, Ntziachristos V, Reiner T, Grimm J.

Photoacoustics. 2017 Mar 21;6:1-8. doi: 10.1016/j.pacs.2017.03.001. eCollection 2017 Jun.

24.

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting.

Büchel GE, Carney B, Tang J, Zeglis BM, Eppinger J, Reiner T.

J Vis Exp. 2017 Mar 9;(121). doi: 10.3791/54694.

25.

Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging.

Fay F, Hansen L, Hectors SJCG, Sanchez-Gaytan BL, Zhao Y, Tang J, Munitz J, Alaarg A, Braza MS, Gianella A, Aaronson SA, Reiner T, Kjems J, Langer R, Hoeben FJM, Janssen HM, Calcagno C, Strijkers GJ, Fayad ZA, Pérez-Medina C, Mulder WJM.

Bioconjug Chem. 2017 May 17;28(5):1413-1421. doi: 10.1021/acs.bioconjchem.7b00086. Epub 2017 May 5.

26.

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines.

Tang J, Pérez-Medina C, Zhao Y, Sadique A, Mulder WJ, Reiner T.

J Vis Exp. 2017 Mar 4;(121). doi: 10.3791/55271.

27.

Development of a New Folate-Derived Ga-68-Based PET Imaging Agent.

Brand C, Longo VA, Groaning M, Weber WA, Reiner T.

Mol Imaging Biol. 2017 Oct;19(5):754-761. doi: 10.1007/s11307-017-1049-y.

28.

Evaluation of [18F]-ATRi as PET tracer for in vivo imaging of ATR in mouse models of brain cancer.

Carlucci G, Carney B, Sadique A, Vansteene A, Tang J, Reiner T.

Nucl Med Biol. 2017 May;48:9-15. doi: 10.1016/j.nucmedbio.2017.01.002. Epub 2017 Jan 16.

29.

Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.

Kossatz S, Carney B, Schweitzer M, Carlucci G, Miloushev VZ, Maachani UB, Rajappa P, Keshari KR, Pisapia D, Weber WA, Souweidane MM, Reiner T.

Cancer Res. 2017 Apr 15;77(8):2112-2123. doi: 10.1158/0008-5472.CAN-16-2850. Epub 2017 Jan 20.

30.

Results after Cementless Medial Oxford Unicompartmental Knee Replacement - Incidence of Radiolucent Lines.

Panzram B, Bertlich I, Reiner T, Walker T, Hagmann S, Weber MA, Gotterbarm T.

PLoS One. 2017 Jan 19;12(1):e0170324. doi: 10.1371/journal.pone.0170324. eCollection 2017.

31.

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M.

Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064.

32.

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer.

Adumeau P, Carnazza KE, Brand C, Carlin SD, Reiner T, Agnew BJ, Lewis JS, Zeglis BM.

Theranostics. 2016 Sep 28;6(12):2267-2277. eCollection 2016.

33.

Imaging-guided revival of nanomedicine?

Senders ML, Fayad ZA, Reiner T, Mulder WJ, Pérez-Medina C.

Nanomedicine (Lond). 2017 Jan;12(2):89-90. Epub 2016 Nov 23. No abstract available.

34.

Immune cell screening of a nanoparticle library improves atherosclerosis therapy.

Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6731-E6740. Epub 2016 Oct 17.

35.

Incorporation and Remodeling of Bone Block Allografts in the Maxillary Reconstruction: A Randomized Clinical Trial.

Deluiz D, Santos Oliveira L, Ramôa Pires F, Reiner T, Armada L, Nunes MA, Muniz Barretto Tinoco E.

Clin Implant Dent Relat Res. 2017 Feb;19(1):180-194. doi: 10.1111/cid.12441. Epub 2016 Sep 8.

PMID:
27717113
36.

Near-Infrared Intraoperative Chemiluminescence Imaging.

Büchel GE, Carney B, Shaffer TM, Tang J, Austin C, Arora M, Zeglis BM, Grimm J, Eppinger J, Reiner T.

ChemMedChem. 2016 Sep 20;11(18):1978-82. doi: 10.1002/cmdc.201600301. Epub 2016 Jul 29.

37.

Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate.

Cook BE, Adumeau P, Membreno R, Carnazza KE, Brand C, Reiner T, Agnew BJ, Lewis JS, Zeglis BM.

Bioconjug Chem. 2016 Aug 17;27(8):1789-95. doi: 10.1021/acs.bioconjchem.6b00235. Epub 2016 Jul 14.

38.

Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy.

Pérez-Medina C, Abdel-Atti D, Tang J, Zhao Y, Fayad ZA, Lewis JS, Mulder WJ, Reiner T.

Nat Commun. 2016 Jun 20;7:11838. doi: 10.1038/ncomms11838.

39.

In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.

Pérez-Medina C, Binderup T, Lobatto ME, Tang J, Calcagno C, Giesen L, Wessel CH, Witjes J, Ishino S, Baxter S, Zhao Y, Ramachandran S, Eldib M, Sánchez-Gaytán BL, Robson PM, Bini J, Granada JF, Fish KM, Stroes ES, Duivenvoorden R, Tsimikas S, Lewis JS, Reiner T, Fuster V, Kjær A, Fisher EA, Fayad ZA, Mulder WJ.

JACC Cardiovasc Imaging. 2016 Aug;9(8):950-61. doi: 10.1016/j.jcmg.2016.01.020. Epub 2016 May 25.

40.

Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent.

Kossatz S, Brand C, Gutiontov S, Liu JT, Lee NY, Gönen M, Weber WA, Reiner T.

Sci Rep. 2016 Feb 22;6:21371. doi: 10.1038/srep21371.

41.

The microRNA-23b/-27b cluster suppresses prostate cancer metastasis via Huntingtin-interacting protein 1-related.

Rice MA, Ishteiwy RA, Magani F, Udayakumar T, Reiner T, Yates TJ, Miller P, Perez-Stable C, Rai P, Verdun R, Dykxhoorn DM, Burnstein KL.

Oncogene. 2016 Sep 8;35(36):4752-61. doi: 10.1038/onc.2016.6. Epub 2016 Feb 22.

42.

Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma.

Kossatz S, Weber WA, Reiner T.

PLoS One. 2016 Jan 25;11(1):e0147752. doi: 10.1371/journal.pone.0147752. eCollection 2016.

43.

Early intervention with Interleukin-1 Receptor Antagonist Protein modulates catabolic microRNA and mRNA expression in cartilage after impact injury.

Genemaras AA, Reiner T, Huang CY, Kaplan L.

Osteoarthritis Cartilage. 2015 Nov;23(11):2036-44. doi: 10.1016/j.joca.2015.05.010.

44.

Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models.

Carney B, Carlucci G, Salinas B, Di Gialleonardo V, Kossatz S, Vansteene A, Longo VA, Bolaender A, Chiosis G, Keshari KR, Weber WA, Reiner T.

Mol Imaging Biol. 2016 Jun;18(3):386-92. doi: 10.1007/s11307-015-0904-y.

45.

(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.

Meyer JP, Houghton JL, Kozlowski P, Abdel-Atti D, Reiner T, Pillarsetty NV, Scholz WW, Zeglis BM, Lewis JS.

Bioconjug Chem. 2016 Feb 17;27(2):298-301. doi: 10.1021/acs.bioconjchem.5b00504. Epub 2015 Oct 28.

46.

Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage.

Reiner T, de Las Pozas A, Parrondo R, Palenzuela D, Cayuso W, Rai P, Perez-Stable C.

Oncoscience. 2015 Sep 1;2(8):703-15. eCollection 2015.

47.

Radioiodinated PARP1 tracers for glioblastoma imaging.

Salinas B, Irwin CP, Kossatz S, Bolaender A, Chiosis G, Pillarsetty N, Weber WA, Reiner T.

EJNMMI Res. 2015 Dec;5(1):123. doi: 10.1186/s13550-015-0123-1. Epub 2015 Sep 4.

48.

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.

Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ.

Sci Adv. 2015 Apr;1(3). pii: e1400223.

49.

Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.

Zeglis BM, Brand C, Abdel-Atti D, Carnazza KE, Cook BE, Carlin S, Reiner T, Lewis JS.

Mol Pharm. 2015 Oct 5;12(10):3575-87. doi: 10.1021/acs.molpharmaceut.5b00294. Epub 2015 Aug 31.

50.

Development of a clickable bimodal fluorescent/PET probe for in vivo imaging.

Paulus A, Desai P, Carney B, Carlucci G, Reiner T, Brand C, Weber WA.

EJNMMI Res. 2015 Dec;5(1):120. doi: 10.1186/s13550-015-0120-4. Epub 2015 Aug 19.

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