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Items: 50


hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning.

Pizon V, Gaudin N, Poteau M, Cifuentes-Diaz C, Demdou R, Heyer V, Reina San Martin B, Azimzadeh J.

Biol Cell. 2020 Jan;112(1):22-37. doi: 10.1111/boc.201900038. Epub 2019 Dec 11.


COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast.

Goulev Y, Matifas A, Heyer V, Reina-San-Martin B, Charvin G.

PLoS One. 2019 Aug 28;14(8):e0220694. doi: 10.1371/journal.pone.0220694. eCollection 2019.


A novel regulatory region controls IgH locus transcription and switch recombination to a subset of isotypes.

Amoretti-Villa R, Rogier M, Robert I, Heyer V, Reina-San-Martin B.

Cell Mol Immunol. 2019 Nov;16(11):887-889. doi: 10.1038/s41423-019-0267-4. Epub 2019 Aug 5. No abstract available.


Allele-Specific CRISPR/Cas9 Correction of a Heterozygous DNM2 Mutation Rescues Centronuclear Myopathy Cell Phenotypes.

Rabai A, Reisser L, Reina-San-Martin B, Mamchaoui K, Cowling BS, Nicot AS, Laporte J.

Mol Ther Nucleic Acids. 2019 Jun 7;16:246-256. doi: 10.1016/j.omtn.2019.02.019. Epub 2019 Feb 27.


PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers.

Beck C, Rodriguez-Vargas JM, Boehler C, Robert I, Heyer V, Hanini N, Gauthier LR, Tissier A, Schreiber V, Elofsson M, Reina San Martin B, Dantzer F.

Cell Death Differ. 2019 Sep;26(9):1615-1630. doi: 10.1038/s41418-018-0233-1. Epub 2018 Nov 15.


Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V.

Cell Rep. 2018 Nov 13;25(7):1994. doi: 10.1016/j.celrep.2018.11.012. No abstract available.


Mediator contributes to IgH locus VDJ rearrangements by promoting usage of most distal V segments.

Dalloul I, Dalloul Z, Le Noir S, Boyer F, Reina-San-Martin B, Cook-Moreau J, Cogné M.

Cell Mol Immunol. 2018 Nov 7. doi: 10.1038/s41423-018-0175-z. [Epub ahead of print] No abstract available.


Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V.

Cell Rep. 2018 May 22;23(8):2443-2454. doi: 10.1016/j.celrep.2018.04.070. Erratum in: Cell Rep. 2018 Nov 13;25(7):1994.


Trib1 Is Overexpressed in Systemic Lupus Erythematosus, While It Regulates Immunoglobulin Production in Murine B Cells.

Simoni L, Delgado V, Ruer-Laventie J, Bouis D, Soley A, Heyer V, Robert I, Gies V, Martin T, Korganow AS, Reina-San-Martin B, Soulas-Sprauel P.

Front Immunol. 2018 Mar 15;9:373. doi: 10.3389/fimmu.2018.00373. eCollection 2018.


Imaging of native transcription factors and histone phosphorylation at high resolution in live cells.

Conic S, Desplancq D, Ferrand A, Fischer V, Heyer V, Reina San Martin B, Pontabry J, Oulad-Abdelghani M, Babu N K, Wright GD, Molina N, Weiss E, Tora L.

J Cell Biol. 2018 Apr 2;217(4):1537-1552. doi: 10.1083/jcb.201709153. Epub 2018 Feb 12.


Med1 deficiency alters the somatic hypermutation spectrum in murine B cells.

Gaudot L, Thomas-Claudepierre AS, Robert I, Schiavo E, Heyer V, Reina-San-Martin B.

Eur J Immunol. 2018 Apr;48(4):720-723. doi: 10.1002/eji.201747258. Epub 2018 Feb 14.


DNA end resection requires constitutive sumoylation of CtIP by CBX4.

Soria-Bretones I, Cepeda-García C, Checa-Rodriguez C, Heyer V, Reina-San-Martin B, Soutoglou E, Huertas P.

Nat Commun. 2017 Jul 24;8(1):113. doi: 10.1038/s41467-017-00183-6.


BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

Tacconi EM, Lai X, Folio C, Porru M, Zonderland G, Badie S, Michl J, Sechi I, Rogier M, Matía García V, Batra AS, Rueda OM, Bouwman P, Jonkers J, Ryan A, Reina-San-Martin B, Hui J, Tang N, Bruna A, Biroccio A, Tarsounas M.

EMBO Mol Med. 2017 Oct;9(10):1398-1414. doi: 10.15252/emmm.201607446.


Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice.

Robert I, Gaudot L, Yélamos J, Noll A, Wong HK, Dantzer F, Schreiber V, Reina-San-Martin B.

Eur J Immunol. 2017 Apr;47(4):665-676. doi: 10.1002/eji.201646757. Epub 2017 Feb 22.


Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.

Lescale C, Lenden Hasse H, Blackford AN, Balmus G, Bianchi JJ, Yu W, Bacoccina L, Jarade A, Clouin C, Sivapalan R, Reina-San-Martin B, Jackson SP, Deriano L.

Cell Rep. 2016 Sep 13;16(11):2967-2979. doi: 10.1016/j.celrep.2016.08.069. Epub 2016 Sep 2.


Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin.

Tsouroula K, Furst A, Rogier M, Heyer V, Maglott-Roth A, Ferrand A, Reina-San-Martin B, Soutoglou E.

Mol Cell. 2016 Jul 21;63(2):293-305. doi: 10.1016/j.molcel.2016.06.002. Epub 2016 Jul 7.


Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

Thomas-Claudepierre AS, Robert I, Rocha PP, Raviram R, Schiavo E, Heyer V, Bonneau R, Luo VM, Reddy JK, Borggrefe T, Skok JA, Reina-San-Martin B.

J Exp Med. 2016 Mar 7;213(3):303-12. doi: 10.1084/jem.20141967. Epub 2016 Feb 22.


Parp3 negatively regulates immunoglobulin class switch recombination.

Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B.

PLoS Genet. 2015 May 22;11(5):e1005240. doi: 10.1371/journal.pgen.1005240. eCollection 2015 May.


Nuclear position dictates DNA repair pathway choice.

Lemaître C, Grabarz A, Tsouroula K, Andronov L, Furst A, Pankotai T, Heyer V, Rogier M, Attwood KM, Kessler P, Dellaire G, Klaholz B, Reina-San-Martin B, Soutoglou E.

Genes Dev. 2014 Nov 15;28(22):2450-63. doi: 10.1101/gad.248369.114. Epub 2014 Nov 3.


Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

Beck C, Robert I, Reina-San-Martin B, Schreiber V, Dantzer F.

Exp Cell Res. 2014 Nov 15;329(1):18-25. doi: 10.1016/j.yexcr.2014.07.003. Epub 2014 Jul 10. Review.


The cohesin complex regulates immunoglobulin class switch recombination.

Thomas-Claudepierre AS, Schiavo E, Heyer V, Fournier M, Page A, Robert I, Reina-San-Martin B.

J Exp Med. 2013 Nov 18;210(12):2495-502. doi: 10.1084/jem.20130166. Epub 2013 Oct 21.


The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Rouaud P, Vincent-Fabert C, Saintamand A, Fiancette R, Marquet M, Robert I, Reina-San-Martin B, Pinaud E, Cogné M, Denizot Y.

J Exp Med. 2013 Jul 29;210(8):1501-7. doi: 10.1084/jem.20130072. Epub 2013 Jul 1.


Functional aspects of PARylation in induced and programmed DNA repair processes: preserving genome integrity and modulating physiological events.

Robert I, Karicheva O, Reina San Martin B, Schreiber V, Dantzer F.

Mol Aspects Med. 2013 Dec;34(6):1138-52. doi: 10.1016/j.mam.2013.02.001. Epub 2013 Feb 26. Review.


A role for the RNA pol II-associated PAF complex in AID-induced immune diversification.

Willmann KL, Milosevic S, Pauklin S, Schmitz KM, Rangam G, Simon MT, Maslen S, Skehel M, Robert I, Heyer V, Schiavo E, Reina-San-Martin B, Petersen-Mahrt SK.

J Exp Med. 2012 Oct 22;209(11):2099-111. doi: 10.1084/jem.20112145. Epub 2012 Sep 24.


DNA in 3R: Repair, Replication, and Recombination.

Coin F, Reina-San-Martin B, Giglia-Mari G, Berneburg M.

Mol Biol Int. 2012;2012:658579. doi: 10.1155/2012/658579. Epub 2012 Mar 28. No abstract available.


Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

Jeevan-Raj BP, Robert I, Heyer V, Page A, Wang JH, Cammas F, Alt FW, Losson R, Reina-San-Martin B.

J Exp Med. 2011 Aug 1;208(8):1649-60. doi: 10.1084/jem.20110118. Epub 2011 Jul 11.


Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.

Buache E, Etique N, Alpy F, Stoll I, Muckensturm M, Reina-San-Martin B, Chenard MP, Tomasetto C, Rio MC.

Oncogene. 2011 Jul 21;30(29):3261-73. doi: 10.1038/onc.2011.41. Epub 2011 Feb 28.


PARP-3 and APLF function together to accelerate nonhomologous end-joining.

Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW.

Mol Cell. 2011 Jan 7;41(1):33-45. doi: 10.1016/j.molcel.2010.12.006.


Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.

Gazumyan A, Timachova K, Yuen G, Siden E, Di Virgilio M, Woo EM, Chait BT, Reina San-Martin B, Nussenzweig MC, McBride KM.

Mol Cell Biol. 2011 Feb;31(3):442-9. doi: 10.1128/MCB.00349-10. Epub 2010 Dec 6.


Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.

Pavri R, Gazumyan A, Jankovic M, Di Virgilio M, Klein I, Ansarah-Sobrinho C, Resch W, Yamane A, Reina San-Martin B, Barreto V, Nieland TJ, Root DE, Casellas R, Nussenzweig MC.

Cell. 2010 Oct 1;143(1):122-33. doi: 10.1016/j.cell.2010.09.017.


Ikaros controls isotype selection during immunoglobulin class switch recombination.

Sellars M, Reina-San-Martin B, Kastner P, Chan S.

J Exp Med. 2009 May 11;206(5):1073-87. doi: 10.1084/jem.20082311. Epub 2009 May 4.


Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination.

Robert I, Dantzer F, Reina-San-Martin B.

J Exp Med. 2009 May 11;206(5):1047-56. doi: 10.1084/jem.20082468. Epub 2009 Apr 13.


AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.

Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC.

Cell. 2008 Dec 12;135(6):1028-38. doi: 10.1016/j.cell.2008.09.062.


MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.

Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, Reina San-Martin B, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC.

Immunity. 2008 May;28(5):630-8. doi: 10.1016/j.immuni.2008.04.002. Epub 2008 May 1.


Structure-based design of a superagonist ligand for the vitamin D nuclear receptor.

Hourai S, Rodrigues LC, Antony P, Reina-San-Martin B, Ciesielski F, Magnier BC, Schoonjans K, Mouriño A, Rochel N, Moras D.

Chem Biol. 2008 Apr;15(4):383-92. doi: 10.1016/j.chembiol.2008.03.016.


A role for AID in chromosome translocations between c-myc and the IgH variable region.

Dorsett Y, Robbiani DF, Jankovic M, Reina-San-Martin B, Eisenreich TR, Nussenzweig MC.

J Exp Med. 2007 Sep 3;204(9):2225-32. Epub 2007 Aug 27. Erratum in: J Exp Med. 2007 Oct;204(10):2491.


The role of activation-induced deaminase in antibody diversification and chromosome translocations.

Ramiro A, Reina San-Martin B, McBride K, Jankovic M, Barreto V, Nussenzweig A, Nussenzweig MC.

Adv Immunol. 2007;94:75-107. Review.


Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells.

Reina-San-Martin B, Chen J, Nussenzweig A, Nussenzweig MC.

Eur J Immunol. 2007 Jan;37(1):235-9.


Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.

Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, Nussenzweig A.

Nat Cell Biol. 2005 Jul;7(7):675-85. Epub 2005 Jun 19.


Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

Reina-San-Martin B, Nussenzweig MC, Nussenzweig A, Difilippantonio S.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1590-5. Epub 2005 Jan 24.


ATM is required for efficient recombination between immunoglobulin switch regions.

Reina-San-Martin B, Chen HT, Nussenzweig A, Nussenzweig MC.

J Exp Med. 2004 Nov 1;200(9):1103-10.


53BP1 is required for class switch recombination.

Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS, Cascalho M, Chen L, Nussenzweig A, Livak F, Nussenzweig MC, Chen J.

J Cell Biol. 2004 May 24;165(4):459-64.


C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

Barreto V, Reina-San-Martin B, Ramiro AR, McBride KM, Nussenzweig MC.

Mol Cell. 2003 Aug;12(2):501-8.


H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation.

Reina-San-Martin B, Difilippantonio S, Hanitsch L, Masilamani RF, Nussenzweig A, Nussenzweig MC.

J Exp Med. 2003 Jun 16;197(12):1767-78.


Genomic instability in mice lacking histone H2AX.

Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, Tessarollo L, Livak F, Manova K, Bonner WM, Nussenzweig MC, Nussenzweig A.

Science. 2002 May 3;296(5569):922-7. Epub 2002 Apr 4.


AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.

Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsuk M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A.

Nature. 2001 Dec 6;414(6864):660-665. doi: 10.1038/414660a.


Significant association between the skewed natural antibody repertoire of Xid mice and resistance to Trypanosoma cruzi infection.

Santos-Lima EC, Vasconcellos R, Reina-San-Martín B, Fesel C, Cordeiro-Da-Silva A, Berneman A, Cosson A, Coutinho A, Minoprio P.

Eur J Immunol. 2001 Feb;31(2):634-45.


A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase.

Reina-San-Martín B, Degrave W, Rougeot C, Cosson A, Chamond N, Cordeiro-Da-Silva A, Arala-Chaves M, Coutinho A, Minoprio P.

Nat Med. 2000 Aug;6(8):890-7.


Lymphocyte polyclonal activation: a pitfall for vaccine design against infectious agents.

Reina-San-Martin B, Cosson A, Minoprio P.

Parasitol Today. 2000 Feb;16(2):62-7. Review.


Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses.

Pérarnau B, Saron MF, Reina San Martin B, Bervas N, Ong H, Soloski MJ, Smith AG, Ure JM, Gairin JE, Lemonnier FA.

Eur J Immunol. 1999 Apr;29(4):1243-52.

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