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Items: 47

1.

Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning.

Gessulat S, Schmidt T, Zolg DP, Samaras P, Schnatbaum K, Zerweck J, Knaute T, Rechenberger J, Delanghe B, Huhmer A, Reimer U, Ehrlich HC, Aiche S, Kuster B, Wilhelm M.

Nat Methods. 2019 Jun;16(6):509-518. doi: 10.1038/s41592-019-0426-7. Epub 2019 May 27.

PMID:
31133760
2.

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence.

Nadai Y, Held K, Joseph S, Ahmed MIM, Hoffmann VS, Peterhoff D, Missanga M, Bauer A, Joachim A, Reimer U, Zerweck J, McCormack S, Cope AV, Tatoud R, Shattock RJ, Robb ML, Sandstroem EG, Hoelscher M, Maboko L, Bakari M, Kroidl A, Wagner R, Weber J, Pollakis G, Geldmacher C.

Front Immunol. 2019 Apr 24;10:717. doi: 10.3389/fimmu.2019.00717. eCollection 2019.

3.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ.

Dittmar G, Hernandez DP, Kowenz-Leutz E, Kirchner M, Kahlert G, Wesolowski R, Baum K, Knoblich M, Hofstätter M, Muller A, Wolf J, Reimer U, Leutz A.

iScience. 2019 Mar 29;13:351-370. doi: 10.1016/j.isci.2019.02.026. Epub 2019 Mar 1.

4.

Analysis of Toxoplasma gondii clonal type-specific antibody reactions in experimentally infected turkeys and chickens.

Maksimov P, Basso W, Zerweck J, Schutkowski M, Reimer U, Maksimov A, Conraths FJ, Schares G.

Int J Parasitol. 2018 Sep;48(11):845-856. doi: 10.1016/j.ijpara.2018.04.004. Epub 2018 Jun 30.

PMID:
29969590
5.

ProteomeTools: Systematic Characterization of 21 Post-translational Protein Modifications by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Using Synthetic Peptides.

Zolg DP, Wilhelm M, Schmidt T, Médard G, Zerweck J, Knaute T, Wenschuh H, Reimer U, Schnatbaum K, Kuster B.

Mol Cell Proteomics. 2018 Sep;17(9):1850-1863. doi: 10.1074/mcp.TIR118.000783. Epub 2018 May 29.

6.

Mining the Human Tissue Proteome for Protein Citrullination.

Lee CY, Wang D, Wilhelm M, Zolg DP, Schmidt T, Schnatbaum K, Reimer U, Pontén F, Uhlén M, Hahne H, Kuster B.

Mol Cell Proteomics. 2018 Jul;17(7):1378-1391. doi: 10.1074/mcp.RA118.000696. Epub 2018 Apr 2.

7.

PROCAL: A Set of 40 Peptide Standards for Retention Time Indexing, Column Performance Monitoring, and Collision Energy Calibration.

Zolg DP, Wilhelm M, Yu P, Knaute T, Zerweck J, Wenschuh H, Reimer U, Schnatbaum K, Kuster B.

Proteomics. 2017 Nov;17(21). doi: 10.1002/pmic.201700263. Epub 2017 Oct 24.

PMID:
28872757
8.

Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.

Loebel M, Eckey M, Sotzny F, Hahn E, Bauer S, Grabowski P, Zerweck J, Holenya P, Hanitsch LG, Wittke K, Borchmann P, Rüffer JU, Hiepe F, Ruprecht K, Behrends U, Meindl C, Volk HD, Reimer U, Scheibenbogen C.

PLoS One. 2017 Jun 12;12(6):e0179124. doi: 10.1371/journal.pone.0179124. eCollection 2017.

9.

Building ProteomeTools based on a complete synthetic human proteome.

Zolg DP, Wilhelm M, Schnatbaum K, Zerweck J, Knaute T, Delanghe B, Bailey DJ, Gessulat S, Ehrlich HC, Weininger M, Yu P, Schlegl J, Kramer K, Schmidt T, Kusebauch U, Deutsch EW, Aebersold R, Moritz RL, Wenschuh H, Moehring T, Aiche S, Huhmer A, Reimer U, Kuster B.

Nat Methods. 2017 Mar;14(3):259-262. doi: 10.1038/nmeth.4153. Epub 2017 Jan 30.

10.

Antibody Responses After Analytic Treatment Interruption in Human Immunodeficiency Virus-1-Infected Individuals on Early Initiated Antiretroviral Therapy.

Stephenson KE, Neubauer GH, Bricault CA, Shields J, Bayne M, Reimer U, Pawlowski N, Knaute T, Zerweck J, Seaman MS, Rosenberg ES, Barouch DH.

Open Forum Infect Dis. 2016 May 19;3(2):ofw100. doi: 10.1093/ofid/ofw100. eCollection 2016 Apr.

11.

Fine specificity of the antibody response to Epstein-Barr nuclear antigen-2 and other Epstein-Barr virus proteins in patients with clinically isolated syndrome: A peptide microarray-based case-control study.

Schlemm L, Giess RM, Rasche L, Pfuhl C, Wakonig K, Behrens JR, Scheibenbogen C, Bellmann-Strobl J, Paul F, Reimer U, Ruprecht K.

J Neuroimmunol. 2016 Aug 15;297:56-62. doi: 10.1016/j.jneuroim.2016.05.012. Epub 2016 May 13.

PMID:
27397076
12.

High-Throughput Microarray Incubations Using Multi-Well Chambers.

Zerweck J, Reimer U, Jansong J, Pawlowski N, Tersch C, Eckey M, Knaute T.

Methods Mol Biol. 2016;1352:19-26. doi: 10.1007/978-1-4939-3037-1_2.

PMID:
26490464
13.

Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis.

Juarez M, Bang H, Hammar F, Reimer U, Dyke B, Sahbudin I, Buckley CD, Fisher B, Filer A, Raza K.

Ann Rheum Dis. 2016 Jun;75(6):1099-107. doi: 10.1136/annrheumdis-2014-206785. Epub 2015 Jul 9.

14.

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys.

Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng'ang'a DM, Seaman MS, Lavine CL, Perry JR, Li W, Colantonio AD, Lewis MG, Chen B, Wenschuh H, Reimer U, Piatak M, Lifson JD, Handley SA, Virgin HW, Koutsoukos M, Lorin C, Voss G, Weijtens M, Pau MG, Schuitemaker H.

Science. 2015 Jul 17;349(6245):320-4. doi: 10.1126/science.aab3886. Epub 2015 Jul 2.

15.

[On the problematic of assessment of complex posttraumatic stress disorder].

Reimer U.

Nervenarzt. 2016 Jan;87(1):91. doi: 10.1007/s00115-014-4186-4. German. No abstract available.

PMID:
25777130
16.

Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.

Burgos ES, Wilczek C, Onikubo T, Bonanno JB, Jansong J, Reimer U, Shechter D.

J Biol Chem. 2015 Apr 10;290(15):9674-89. doi: 10.1074/jbc.M115.636894. Epub 2015 Feb 24.

17.

Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development.

Stephenson KE, Neubauer GH, Reimer U, Pawlowski N, Knaute T, Zerweck J, Korber BT, Barouch DH.

J Immunol Methods. 2015 Jan;416:105-23. doi: 10.1016/j.jim.2014.11.006. Epub 2014 Nov 15.

18.

Mass-spectrometry-based draft of the human proteome.

Wilhelm M, Schlegl J, Hahne H, Gholami AM, Lieberenz M, Savitski MM, Ziegler E, Butzmann L, Gessulat S, Marx H, Mathieson T, Lemeer S, Schnatbaum K, Reimer U, Wenschuh H, Mollenhauer M, Slotta-Huspenina J, Boese JH, Bantscheff M, Gerstmair A, Faerber F, Kuster B.

Nature. 2014 May 29;509(7502):582-7. doi: 10.1038/nature13319.

PMID:
24870543
19.

Multiple sclerosis: the elevated antibody response to Epstein-Barr virus primarily targets, but is not confined to, the glycine-alanine repeat of Epstein-Barr nuclear antigen-1.

Ruprecht K, Wunderlich B, Gieß R, Meyer P, Loebel M, Lenz K, Hofmann J, Rosche B, Wengert O, Paul F, Reimer U, Scheibenbogen C.

J Neuroimmunol. 2014 Jul 15;272(1-2):56-61. doi: 10.1016/j.jneuroim.2014.04.005. Epub 2014 Apr 16.

PMID:
24798244
20.

Peptide microarrays enable rapid mimotope optimization for pharmacokinetic analysis of the novel therapeutic antibody IMAB362.

Schnatbaum K, Schmoldt HU, Daneschdar M, Plum LM, Jansong J, Zerweck J, Kühne Y, Masch A, Wenschuh H, Fiedler M, Türeci Ö, Sahin U, Reimer U.

Biotechnol J. 2014 Apr;9(4):545-54. doi: 10.1002/biot.201300456. Epub 2014 Mar 7.

PMID:
24497417
21.

Serotyping of Toxoplasma gondii in cats (Felis domesticus) reveals predominance of type II infections in Germany.

Maksimov P, Zerweck J, Dubey JP, Pantchev N, Frey CF, Maksimov A, Reimer U, Schutkowski M, Hosseininejad M, Ziller M, Conraths FJ, Schares G.

PLoS One. 2013 Nov 7;8(11):e80213. doi: 10.1371/journal.pone.0080213. eCollection 2013.

22.

Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.

Ho MC, Wilczek C, Bonanno JB, Xing L, Seznec J, Matsui T, Carter LG, Onikubo T, Kumar PR, Chan MK, Brenowitz M, Cheng RH, Reimer U, Almo SC, Shechter D.

PLoS One. 2013;8(2):e57008. doi: 10.1371/journal.pone.0057008. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/e6b5348e-9052-4a3b-8f06-90d01dc88fc2.

23.

Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001).

Barouch DH, Liu J, Peter L, Abbink P, Iampietro MJ, Cheung A, Alter G, Chung A, Dugast AS, Frahm N, McElrath MJ, Wenschuh H, Reimer U, Seaman MS, Pau MG, Weijtens M, Goudsmit J, Walsh SR, Dolin R, Baden LR.

J Infect Dis. 2013 Jan 15;207(2):248-56. doi: 10.1093/infdis/jis671. Epub 2012 Nov 2.

24.

rapmad: Robust analysis of peptide microarray data.

Renard BY, Löwer M, Kühne Y, Reimer U, Rothermel A, Türeci O, Castle JC, Sahin U.

BMC Bioinformatics. 2011 Aug 4;12:324. doi: 10.1186/1471-2105-12-324.

25.

Antibody signatures defined by high-content peptide microarray analysis.

Masch A, Zerweck J, Reimer U, Wenschuh H, Schutkowski M.

Methods Mol Biol. 2010;669:161-72. doi: 10.1007/978-1-60761-845-4_13.

PMID:
20857365
26.

Novel small molecule bradykinin B2 receptor antagonists.

Gibson C, Schnatbaum K, Pfeifer JR, Locardi E, Paschke M, Reimer U, Richter U, Scharn D, Faussner A, Tradler T.

J Med Chem. 2009 Jul 23;52(14):4370-9. doi: 10.1021/jm9002445.

PMID:
19552431
27.

Prediction of linear B-cell epitopes.

Reimer U.

Methods Mol Biol. 2009;524:335-44. doi: 10.1007/978-1-59745-450-6_24.

PMID:
19377956
28.

High-content peptide microarrays for deciphering kinase specificity and biology.

Schutkowski M, Reimer U, Panse S, Dong L, Lizcano JM, Alessi DR, Schneider-Mergener J.

Angew Chem Int Ed Engl. 2004 May 10;43(20):2671-4. No abstract available.

PMID:
18629986
29.

Design and synthesis of a new class of selective integrin alpha5beta1 antagonists.

Stragies R, Osterkamp F, Zischinsky G, Vossmeyer D, Kalkhof H, Reimer U, Zahn G.

J Med Chem. 2007 Aug 9;50(16):3786-94. Epub 2007 Jul 6.

PMID:
17616113
30.

Translating peptides into small molecules.

Hummel G, Reineke U, Reimer U.

Mol Biosyst. 2006 Oct;2(10):499-508. Epub 2006 Aug 24. No abstract available.

PMID:
17216031
31.

Peptide arrays for kinase profiling.

Schutkowski M, Reineke U, Reimer U.

Chembiochem. 2005 Mar;6(3):513-21. Review. No abstract available.

PMID:
15742386
32.

Monte Carlo study of surfactant adsorption on heterogeneous solid surfaces.

Reimer U, Wahab M, Schiller P, Mögel HJ.

Langmuir. 2005 Feb 15;21(4):1640-6.

PMID:
15697319
33.

Profiling of generic anti-phosphopeptide antibodies and kinases with peptide microarrays using radioactive and fluorescence-based assays.

Panse S, Dong L, Burian A, Carus R, Schutkowski M, Reimer U, Schneider-Mergener J.

Mol Divers. 2004;8(3):291-9.

PMID:
15384422
34.

Target specificity analysis of the Abl kinase using peptide microarray data.

Rychlewski L, Kschischo M, Dong L, Schutkowski M, Reimer U.

J Mol Biol. 2004 Feb 13;336(2):307-11.

PMID:
14757045
35.

Peptide arrays: from macro to micro.

Reimer U, Reineke U, Schneider-Mergener J.

Curr Opin Biotechnol. 2002 Aug;13(4):315-20. Review.

PMID:
12323352
36.

Substrate-based design of reversible Pin1 inhibitors.

Zhang Y, Füssel S, Reimer U, Schutkowski M, Fischer G.

Biochemistry. 2002 Oct 1;41(39):11868-77.

PMID:
12269831
37.
38.
39.

Increased backbone flexibility in threonine45-phosphorylated hirudin upon pH change.

Kipping M, Zarnt T, Kiessig S, Reimer U, Fischer G, Bayer P.

Biochemistry. 2001 Jul 10;40(27):7957-63.

PMID:
11434764
40.

Nonprolyl cis peptide bonds in unfolded proteins cause complex folding kinetics.

Pappenberger G, Aygün H, Engels JW, Reimer U, Fischer G, Kiefhaber T.

Nat Struct Biol. 2001 May;8(5):452-8.

PMID:
11323723
41.

Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases.

Schiene C, Reimer U, Schutkowski M, Fischer G.

FEBS Lett. 1998 Aug 7;432(3):202-6.

42.

Side-chain effects on peptidyl-prolyl cis/trans isomerisation.

Reimer U, Scherer G, Drewello M, Kruber S, Schutkowski M, Fischer G.

J Mol Biol. 1998 Jun 5;279(2):449-60.

PMID:
9642049
43.

Role of phosphorylation in determining the backbone dynamics of the serine/threonine-proline motif and Pin1 substrate recognition.

Schutkowski M, Bernhardt A, Zhou XZ, Shen M, Reimer U, Rahfeld JU, Lu KP, Fischer G.

Biochemistry. 1998 Apr 21;37(16):5566-75.

PMID:
9548941
44.

Intramolecular assistance of cis/trans isomerization of the histidine-proline moiety.

Reimer U, el Mokdad N, Schutkowski M, Fischer G.

Biochemistry. 1997 Nov 11;36(45):13802-8.

PMID:
9374856
45.

Conformational state of a 25-mer peptide from the cyclophilin-binding loop of the HIV type 1 capsid protein.

Reimer U, Drewello M, Jakob M, Fischer G, Schutkowski M.

Biochem J. 1997 Aug 15;326 ( Pt 1):181-5.

46.

Extended binding sites of cyclophilin as revealed by the interaction with HIV-1 Gag polyprotein derived oligopeptides.

Schutkowski M, Drewello M, Wöllner S, Jakob M, Reimer U, Scherer G, Schierhorn A, Fischer G.

FEBS Lett. 1996 Oct 7;394(3):289-94.

47.

Effects of the beta 2-adrenoceptor agonists fenoterol and salbutamol on force of contraction in isolated human ventricular myocardium.

Mügge A, Posselt D, Reimer U, Schmitz W, Scholz H.

Klin Wochenschr. 1985 Jan 2;63(1):26-31.

PMID:
3974172

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