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Destruction of Staphylococcus aureus and the impact of chlortetracycline on biomethane production during anaerobic digestion of chicken manure.

Kirby ME, Mirza MW, Leigh T, Oldershaw L, Reilly M, Jeffery S.

Heliyon. 2019 Nov 14;5(11):e02749. doi: 10.1016/j.heliyon.2019.e02749. eCollection 2019 Nov.


Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts.

Swift LM, Jaimes R 3rd, McCullough D, Burke M, Reilly M, Maeda T, Zhang H, Ishibashi N, Rogers JM, Posnack NG.

J Vis Exp. 2019 Nov 7;(153). doi: 10.3791/60472.


Sex Differences in Genomic Drivers of Adipose Distribution and Related Cardiometabolic Disorders: Opportunities for Precision Medicine.

Lumish HS, O'Reilly M, Reilly MP.

Arterioscler Thromb Vasc Biol. 2019 Nov 21:ATVBAHA119313154. doi: 10.1161/ATVBAHA.119.313154. [Epub ahead of print]


Lack of an Exposure Response and Interaction with HLA-DPβ1 and DRβ1 Polymorphisms in the Development of Beryllium Toxicity in a High Beryllium Exposure Cohort.

Widyaningsih V, Rosenman K, Reilly MJ, Wang L, Pathak DR, Gardiner JC, Rice C, Monos D, Rossman M.

J Occup Environ Med. 2019 Nov 15. doi: 10.1097/JOM.0000000000001766. [Epub ahead of print]


Quantifying pediatric patient need for second- and third-line HIV treatment: A tool for decision-making in resource-limited settings.

Mohammed P, Linden A, Reilly M.

PLoS One. 2019 Nov 14;14(11):e0224226. doi: 10.1371/journal.pone.0224226. eCollection 2019.


Physiologic widening of the medial clear space: What's normal?

Gibson PD, Ippolito JA, Hwang JS, Didesch J, Koury KL, Reilly MC, Adams M, Sirkin M.

J Clin Orthop Trauma. 2019 Oct;10(Suppl 1):S62-S64. doi: 10.1016/j.jcot.2019.04.016. Epub 2019 Apr 23.


The Burden of Work-Related Asthma in Michigan, 1988-2018.

Reilly MJ, Wang L, Rosenman KD.

Ann Am Thorac Soc. 2019 Nov 4. doi: 10.1513/AnnalsATS.201905-401OC. [Epub ahead of print]


Routine blood monitoring in maintenance immunoglobulin treatment of inflammatory neuropathy: Is it clinically relevant?

Keh R, Kahlil A, Nihoyannopoulos L, Compton L, Kapoor M, Gosal D, Manji H, Rossor AM, Reilly MM, Lunn MP, Lavin TM, Carr AS.

J Neurol Sci. 2019 Oct 25;408:116527. doi: 10.1016/j.jns.2019.116527. [Epub ahead of print]


Differential phenotypic expression of a novel PDHA1 mutation in a female monozygotic twin pair.

Horga A, Woodward CE, Mills A, Pareés I, Hargreaves IP, Brown RM, Bugiardini E, Brooks T, Manole A, Remzova E, Rahman S, Reilly MM, Houlden H, Sweeney MG, Brown GK, Polke JM, Gago F, Parton MJ, Pitceathly RDS, Hanna MG.

Hum Genet. 2019 Dec;138(11-12):1313-1322. doi: 10.1007/s00439-019-02075-9. Epub 2019 Oct 31.


The Development, Growth, and Regeneration of the Crystalline Lens: A Review.

Kumar B, Reilly MA.

Curr Eye Res. 2019 Oct 31:1-14. doi: 10.1080/02713683.2019.1681003. [Epub ahead of print]


Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease.

Evans TD, Zhang X, Clark RE, Alisio A, Song E, Zhang H, Reilly MP, Stitziel NO, Razani B.

Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2480-2491. doi: 10.1161/ATVBAHA.119.313443. Epub 2019 Oct 24.


Corralling a black swan: natural range of variation in a forest landscape driven by rare, extreme events.

Donato DC, Halofsky JS, Reilly MJ.

Ecol Appl. 2019 Oct 8:e02013. doi: 10.1002/eap.2013. [Epub ahead of print]


Feasibility and Acceptability of a Web-Based, Gender-Specific Intervention for Women with Substance Use Disorders.

Sugarman DE, Meyer LE, Reilly ME, Greenfield SF.

J Womens Health (Larchmt). 2019 Oct 4. doi: 10.1089/jwh.2018.7519. [Epub ahead of print]


Plasma neurofilament light chain concentration is increased and correlates with the severity of neuropathy in hereditary transthyretin amyloidosis.

Kapoor M, Foiani M, Heslegrave A, Zetterberg H, Lunn MP, Malaspina A, Gillmore JD, Rossor AM, Reilly MM.

J Peripher Nerv Syst. 2019 Oct 3. doi: 10.1111/jns.12350. [Epub ahead of print]


Next-generation sequencing in Charcot-Marie-Tooth disease: opportunities and challenges.

Pipis M, Rossor AM, Laura M, Reilly MM.

Nat Rev Neurol. 2019 Nov;15(11):644-656. doi: 10.1038/s41582-019-0254-5. Epub 2019 Oct 3. Review.


Genetic and phenotypic characterisation of inherited myopathies in a tertiary neuromuscular centre.

Bugiardini E, Khan AM, Phadke R, Lynch DS, Cortese A, Feng L, Gang Q, Pittman AM, Morrow JM, Turner C, Carr AS, Quinlivan R, Rossor AM, Holton JL, Parton M, Blake JC, Reilly MM, Houlden H, Matthews E, Hanna MG.

Neuromuscul Disord. 2019 Oct;29(10):747-757. doi: 10.1016/j.nmd.2019.08.003. Epub 2019 Aug 19.


Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers.

Gu S, Biswas S, Rodriguez L, Li Z, Li Y, Riquelme MA, Shi W, Wang K, White TW, Reilly M, Lo WK, Jiang JX.

Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):4021-4032. doi: 10.1167/iovs.18-26270.


Lens Stretching Modulates Lens Epithelial Cell Proliferation via YAP Regulation.

Kumar B, Chandler HL, Plageman T, Reilly MA.

Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):3920-3929. doi: 10.1167/iovs.19-26893.


Association of blood group and red blood cell transfusion with the incidence of antepartum, peripartum and postpartum venous thromboembolism.

Wang C, Le Ray I, Lee B, Wikman A, Reilly M.

Sci Rep. 2019 Sep 19;9(1):13535. doi: 10.1038/s41598-019-49566-3.


Comparison of Effectiveness of Alcohol Septal Ablation Versus Ventricular Septal Myectomy on Acute Care Use for Cardiovascular Disease in Patients With Hypertrophic Cardiomyopathy.

Shimada YJ, Goto T, Takayama H, Brown DFM, Homma S, Maurer MS, Reilly MP, Hasegawa K.

Am J Cardiol. 2019 Oct 15;124(8):1272-1278. doi: 10.1016/j.amjcard.2019.07.031. Epub 2019 Jul 29.


C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells.

Lynch E, Semrad T, Belsito VS, FitzGibbons C, Reilly M, Hayakawa K, Suzuki M.

Dis Model Mech. 2019 Aug 16;12(8). pii: dmm039552. doi: 10.1242/dmm.039552.


Treating the Orthopaedic Trauma Knowledge Gap: Quantification of Orthopaedic Resident Knowledge Gaps and Validation of a Multimodal Course to Address the Deficiencies.

Graves ML, Paryavi E, Hung L, Reilly MC, Guy P, O'Toole RV.

J Orthop Trauma. 2019 Aug 13. doi: 10.1097/BOT.0000000000001607. [Epub ahead of print]


Gene replacement therapy after neuropathy onset provides therapeutic benefit in a model of CMT1X.

Kagiava A, Richter J, Tryfonos C, Karaiskos C, Heslegrave AJ, Sargiannidou I, Rossor AM, Zetterberg H, Reilly MM, Christodoulou C, Kleopa KA.

Hum Mol Genet. 2019 Aug 14. pii: ddz199. doi: 10.1093/hmg/ddz199. [Epub ahead of print]


Clozaril Withdrawal Induced Catatonia

McGuire E, Reilly M.

Ir Med J. 2019 May 9;112(5):938.


A protective smooth muscle cell transition in atherosclerosis.

Pan H, Reilly MP.

Nat Med. 2019 Aug;25(8):1194-1195. doi: 10.1038/s41591-019-0541-0. No abstract available.


Charcot-Marie-Tooth disease and related disorders: an evolving landscape.

Laurá M, Pipis M, Rossor AM, Reilly MM.

Curr Opin Neurol. 2019 Oct;32(5):641-650. doi: 10.1097/WCO.0000000000000735.


Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation.

Zhuang T, Liu J, Chen X, Zhang L, Pi J, Sun H, Li L, Bauer R, Wang H, Yu Z, Zhang Q, Tomlinson B, Chan P, Zheng X, Morrisey E, Liu Z, Reilly M, Zhang Y.

Circ Res. 2019 Aug 30;125(6):590-605. doi: 10.1161/CIRCRESAHA.118.314402. Epub 2019 Jul 18.


Evaluation of Personality Perception in Men Before and After Facial Cosmetic Surgery.

Parsa KM, Gao W, Lally J, Davison SP, Reilly MJ.

JAMA Facial Plast Surg. 2019 Jul 11. doi: 10.1001/jamafacial.2019.0463. [Epub ahead of print]


Application of Proteomics Profiling for Biomarker Discovery in Hypertrophic Cardiomyopathy.

Shimada YJ, Hasegawa K, Kochav SM, Mohajer P, Jung J, Maurer MS, Reilly MP, Fifer MA.

J Cardiovasc Transl Res. 2019 Dec;12(6):569-579. doi: 10.1007/s12265-019-09896-z. Epub 2019 Jul 5.


Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases.

Haile PA, Casillas LN, Votta BJ, Wang GZ, Charnley AK, Dong X, Bury MJ, Romano JJ, Mehlmann JF, King BW, Erhard KF, Hanning CR, Lipshutz DB, Desai BM, Capriotti CA, Schaeffer MC, Berger SB, Mahajan MK, Reilly MA, Nagilla R, Rivera EJ, Sun HH, Kenna JK, Beal AM, Ouellette MT, Kelly M, Stemp G, Convery MA, Vossenkämper A, MacDonald TT, Gough PJ, Bertin J, Marquis RW.

J Med Chem. 2019 Jul 25;62(14):6482-6494. doi: 10.1021/acs.jmedchem.9b00575. Epub 2019 Jul 2.


Altered expression of aquaporin 1 and aquaporin 5 in the cornea after primary blast exposure.

Ríos JD, Choi JH, McDaniel JS, Becera S, Bice L, Johnson P, Cleland JM, Glickman RD, Reilly MA, Gray W, Sponsel WE, Lund BJ.

Mol Vis. 2019 Jun 5;25:283-294. eCollection 2019.


Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment.

Jackson JJ, Ketcham JM, Younai A, Abraham B, Biannic B, Beck HP, Bui MHT, Chian D, Cutler G, Diokno R, Hu DX, Jacobson S, Karbarz E, Kassner PD, Marshall L, McKinnell J, Meleza C, Okal A, Pookot D, Reilly MK, Robles O, Shunatona HP, Talay O, Walker JR, Wadsworth A, Wustrow DJ, Zibinsky M.

J Med Chem. 2019 Jul 11;62(13):6190-6213. doi: 10.1021/acs.jmedchem.9b00506. Epub 2019 Jul 1.


Is There a Selfie Epidemic?

Reilly MJ, Parsa KM, Biel M.

JAMA Facial Plast Surg. 2019 Jun 27. doi: 10.1001/jamafacial.2019.0419. [Epub ahead of print] No abstract available.


Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.

Harris PA, Marinis JM, Lich JD, Berger SB, Chirala A, Cox JA, Eidam PM, Finger JN, Gough PJ, Jeong JU, Kang J, Kasparcova V, Leister LK, Mahajan MK, Miller G, Nagilla R, Ouellette MT, Reilly MA, Rendina AR, Rivera EJ, Sun HH, Thorpe JH, Totoritis RD, Wang W, Wu D, Zhang D, Bertin J, Marquis RW.

ACS Med Chem Lett. 2019 May 9;10(6):857-862. doi: 10.1021/acsmedchemlett.9b00108. eCollection 2019 Jun 13.


PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation.

Chelban V, Wilson MP, Warman Chardon J, Vandrovcova J, Zanetti MN, Zamba-Papanicolaou E, Efthymiou S, Pope S, Conte MR, Abis G, Liu YT, Tribollet E, Haridy NA, Botía JA, Ryten M, Nicolaou P, Minaidou A, Christodoulou K, Kernohan KD, Eaton A, Osmond M, Ito Y, Bourque P, Jepson JEC, Bello O, Bremner F, Cordivari C, Reilly MM, Foiani M, Heslegrave A, Zetterberg H, Heales SJR, Wood NW, Rothman JE, Boycott KM, Mills PB, Clayton PT, Houlden H; Care4Rare Canada Consortium and the SYNaPS Study Group.

Ann Neurol. 2019 Aug;86(2):225-240. doi: 10.1002/ana.25524. Epub 2019 Jul 1.


Endothelial Forkhead Box Transcription Factor P1 Regulates Pathological Cardiac Remodeling Through Transforming Growth Factor-β1-Endothelin-1 Signal Pathway.

Liu J, Zhuang T, Pi J, Chen X, Zhang Q, Li Y, Wang H, Shen Y, Tomlinson B, Chan P, Yu Z, Cheng Y, Zheng X, Reilly M, Morrisey E, Zhang L, Liu Z, Zhang Y.

Circulation. 2019 Aug 20;140(8):665-680. doi: 10.1161/CIRCULATIONAHA.119.039767. Epub 2019 Jun 10.


Cilia in hereditary cerebral anomalies.

Thomas S, Boutaud L, Reilly ML, Benmerah A.

Biol Cell. 2019 Sep;111(9):217-231. doi: 10.1111/boc.201900012. Epub 2019 Jun 17. Review.


Stochastic imputation for integrated transcriptome association analysis of a longitudinally measured trait.

Ray EL, Qian J, Brecha R, Reilly MP, Foulkes AS.

Stat Methods Med Res. 2019 Jun 7:962280219852720. doi: 10.1177/0962280219852720. [Epub ahead of print]


Expanding the spectrum of genes responsible for hereditary motor neuropathies.

Previtali SC, Zhao E, Lazarevic D, Pipitone GB, Fabrizi GM, Manganelli F, Mazzeo A, Pareyson D, Schenone A, Taroni F, Vita G, Bellone E, Ferrarini M, Garibaldi M, Magri S, Padua L, Pennisi E, Pisciotta C, Riva N, Scaioli V, Scarlato M, Tozza S, Geroldi A, Jordanova A, Ferrari M, Molineris I, Reilly MM, Comi G, Carrera P, Devoto M, Bolino A.

J Neurol Neurosurg Psychiatry. 2019 Oct;90(10):1171-1179. doi: 10.1136/jnnp-2019-320717. Epub 2019 Jun 5.


Acute blockade of PACAP-dependent activity in the ventromedial nucleus of the hypothalamus disrupts leptin-induced behavioral and molecular changes in rats.

Hurley M, Anderson E, Chen C, Maunze B, Hess E, Block M, Patel N, Cooper Z, McCoy R, Dabra T, Conley W, Reilly M, Hearing M, Choi S.

Neuroendocrinology. 2019 Jun 6. doi: 10.1159/000501337. [Epub ahead of print]


High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.

Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, Chen G, Reilly MP, Kirabo A.

JCI Insight. 2019 Jun 4;5. pii: 126241. doi: 10.1172/jci.insight.126241.


Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.

Ramanjulu JM, Pesiridis GS, Yang J, Concha N, Singhaus R, Zhang SY, Tran JL, Moore P, Lehmann S, Eberl HC, Muelbaier M, Schneck JL, Clemens J, Adam M, Mehlmann J, Romano J, Morales A, Kang J, Leister L, Graybill TL, Charnley AK, Ye G, Nevins N, Behnia K, Wolf AI, Kasparcova V, Nurse K, Wang L, Puhl AC, Li Y, Klein M, Hopson CB, Guss J, Bantscheff M, Bergamini G, Reilly MA, Lian Y, Duffy KJ, Adams J, Foley KP, Gough PJ, Marquis RW, Smothers J, Hoos A, Bertin J.

Nature. 2019 Jun;570(7761):E53. doi: 10.1038/s41586-019-1265-5.


Autosomal dominant optic atrophy and cataract "plus" phenotype including axonal neuropathy.

Horga A, Bugiardini E, Manole A, Bremner F, Jaunmuktane Z, Dankwa L, Rebelo AP, Woodward CE, Hargreaves IP, Cortese A, Pittman AM, Brandner S, Polke JM, Pitceathly RDS, Züchner S, Hanna MG, Scherer SS, Houlden H, Reilly MM.

Neurol Genet. 2019 Apr 1;5(2):e322. doi: 10.1212/NXG.0000000000000322. eCollection 2019 Apr.


A multicenter retrospective study of charcot-marie-tooth disease type 4B (CMT4B) associated with mutations in myotubularin-related proteins (MTMRs).

Pareyson D, Stojkovic T, Reilly MM, Leonard-Louis S, Laurà M, Blake J, Parman Y, Battaloglu E, Tazir M, Bellatache M, Bonello-Palot N, Lévy N, Sacconi S, Guimarães-Costa R, Attarian S, Latour P, Solé G, Megarbane A, Horvath R, Ricci G, Choi BO, Schenone A, Gemelli C, Geroldi A, Sabatelli M, Luigetti M, Santoro L, Manganelli F, Quattrone A, Valentino P, Murakami T, Scherer SS, Dankwa L, Shy ME, Bacon CJ, Herrmann DN, Zambon A, Tramacere I, Pisciotta C, Magri S, Previtali SC, Bolino A.

Ann Neurol. 2019 Jul;86(1):55-67. doi: 10.1002/ana.25500. Epub 2019 May 27.


Author Correction: Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia.

Cortese A, Simone R, Sullivan R, Vandrovcova J, Tariq H, Yau WY, Humphrey J, Jaunmuktane Z, Sivakumar P, Polke J, Ilyas M, Tribollet E, Tomaselli PJ, Devigili G, Callegari I, Versino M, Salpietro V, Efthymiou S, Kaski D, Wood NW, Andrade NS, Buglo E, Rebelo A, Rossor AM, Bronstein A, Fratta P, Marques WJ, Züchner S, Reilly MM, Houlden H.

Nat Genet. 2019 May;51(5):920. doi: 10.1038/s41588-019-0422-y.


Balance impairment in pediatric charcot-marie-tooth disease.

Estilow T, Glanzman AM, Burns J, Harrington A, Cornett K, Menezes MP, Shy R, Moroni I, Pagliano E, Pareyson D, Bhandari T, Muntoni F, Laurá M, Reilly MM, Finkel RS, Eichinger KJ, Herrmann DN, Troutman G, Bray P, Halaki M, Shy ME, Yum SW; CMTPedS STUDY GROUP.

Muscle Nerve. 2019 Sep;60(3):242-249. doi: 10.1002/mus.26500. Epub 2019 May 15.


Correlative SICM-FCM reveals changes in morphology and kinetics of endocytic pits induced by disease-associated mutations in dynamin.

Ali T, Bednarska J, Vassilopoulos S, Tran M, Diakonov IA, Ziyadeh-Isleem A, Guicheney P, Gorelik J, Korchev YE, Reilly MM, Bitoun M, Shevchuk A.

FASEB J. 2019 Jul;33(7):8504-8518. doi: 10.1096/fj.201802635R. Epub 2019 Apr 24.


Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.

Harris PA, Faucher N, George N, Eidam PM, King BW, White GV, Anderson NA, Bandyopadhyay D, Beal AM, Beneton V, Berger SB, Campobasso N, Campos S, Capriotti CA, Cox JA, Daugan A, Donche F, Fouchet MH, Finger JN, Geddes B, Gough PJ, Grondin P, Hoffman BL, Hoffman SJ, Hutchinson SE, Jeong JU, Jigorel E, Lamoureux P, Leister LK, Lich JD, Mahajan MK, Meslamani J, Mosley JE, Nagilla R, Nassau PM, Ng SL, Ouellette MT, Pasikanti KK, Potvain F, Reilly MA, Rivera EJ, Sautet S, Schaeffer MC, Sehon CA, Sun H, Thorpe JH, Totoritis RD, Ward P, Wellaway N, Wisnoski DD, Woolven JM, Bertin J, Marquis RW.

J Med Chem. 2019 May 23;62(10):5096-5110. doi: 10.1021/acs.jmedchem.9b00318. Epub 2019 May 2.


Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.

Reisdorf WC, Xie Q, Zeng X, Xie W, Rajpal N, Hoang B, Burgert ME, Kumar V, Hurle MR, Rajpal DK, O'Donnell S, MacDonald TT, Vossenkämper A, Wang L, Reilly M, Votta BJ, Sanchez Y, Agarwal P.

PLoS One. 2019 Apr 19;14(4):e0215033. doi: 10.1371/journal.pone.0215033. eCollection 2019.


Development of MRC Centre MRI calf muscle fat fraction protocol as a sensitive outcome measure in Hereditary Sensory Neuropathy Type 1.

Kugathasan U, Evans MRB, Morrow JM, Sinclair CDJ, Thornton JS, Yousry TA, Hornemann T, Suriyanarayanan S, Owusu-Ansah K, Lauria G, Lombardi R, Polke JM, Wilson E, Bennett DLH, Houlden H, Hanna MG, Blake JC, Laura M, Reilly MM.

J Neurol Neurosurg Psychiatry. 2019 Aug;90(8):895-906. doi: 10.1136/jnnp-2018-320198. Epub 2019 Apr 17.


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