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Items: 26


Differential Effects of Rapamycin on Glucose Metabolism in Nine Inbred Strains.

Reifsnyder PC, Te A, Harrison DE.

J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):50-57. doi: 10.1093/gerona/glz157.


Cardioprotective effects of dietary rapamycin on adult female C57BLKS/J-Leprdb mice.

Reifsnyder PC, Ryzhov S, Flurkey K, Anunciado-Koza RP, Mills I, Harrison DE, Koza RA.

Ann N Y Acad Sci. 2018 Apr;1418(1):106-117. doi: 10.1111/nyas.13557. Epub 2018 Jan 29.


Rapamycin treatment benefits glucose metabolism in mouse models of type 2 diabetes.

Reifsnyder PC, Flurkey K, Te A, Harrison DE.

Aging (Albany NY). 2016 Nov 30;8(11):3120-3130. doi: 10.18632/aging.101117.


Rapamycin ameliorates nephropathy despite elevating hyperglycemia in a polygenic mouse model of type 2 diabetes, NONcNZO10/LtJ.

Reifsnyder PC, Doty R, Harrison DE.

PLoS One. 2014 Dec 4;9(12):e114324. doi: 10.1371/journal.pone.0114324. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119748.


Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ.

Leiter EH, Strobel M, O'Neill A, Schultz D, Schile A, Reifsnyder PC.

J Diabetes Res. 2013;2013:165327. doi: 10.1155/2013/165327. Epub 2013 Apr 8.


Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice.

Chen YG, Scheuplein F, Driver JP, Hewes AA, Reifsnyder PC, Leiter EH, Serreze DV.

J Immunol. 2011 Apr 1;186(7):4278-84. doi: 10.4049/jimmunol.1003733. Epub 2011 Feb 25.


Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene.

Nicholson A, Reifsnyder PC, Malcolm RD, Lucas CA, MacGregor GR, Zhang W, Leiter EH.

Obesity (Silver Spring). 2010 Oct;18(10):1902-5. doi: 10.1038/oby.2009.477. Epub 2010 Jan 7.


NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice.

Leiter EH, Reifsnyder PC, Wallace R, Li R, King B, Churchill GC.

Diabetes. 2009 Jul;58(7):1700-3. doi: 10.2337/db09-0120. Epub 2009 Mar 31.


Adipokine and insulin profiles distinguish diabetogenic and non-diabetogenic obesities in mice.

Leiter EH, Reifsnyder PC, Xiao Q, Mistry J.

Obesity (Silver Spring). 2007 Aug;15(8):1961-8.


Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.

Chen J, Chen YG, Reifsnyder PC, Schott WH, Lee CH, Osborne M, Scheuplein F, Haag F, Koch-Nolte F, Serreze DV, Leiter EH.

J Immunol. 2006 Apr 15;176(8):4590-9.


Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis.

Lee CH, Chen YG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M, Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH.

Diabetes. 2006 Jan;55(1):171-8.


"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells.

Chen J, Reifsnyder PC, Scheuplein F, Schott WH, Mileikovsky M, Soodeen-Karamath S, Nagy A, Dosch MH, Ellis J, Koch-Nolte F, Leiter EH.

Mamm Genome. 2005 Oct;16(10):775-83. Epub 2005 Oct 29.


Differential endocrine responses to rosiglitazone therapy in new mouse models of type 2 diabetes.

Leiter EH, Reifsnyder PC, Zhang W, Pan HJ, Xiao Q, Mistry J.

Endocrinology. 2006 Feb;147(2):919-26. Epub 2005 Oct 27.


Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis.

Lee CH, Reifsnyder PC, Naggert JK, Wasserfall C, Atkinson MA, Chen J, Leiter EH.

Diabetes. 2005 Sep;54(9):2525-32.


Conditioning the genome identifies additional diabetes resistance loci in Type I diabetes resistant NOR/Lt mice.

Reifsnyder PC, Li R, Silveira PA, Churchill G, Serreze DV, Leiter EH.

Genes Immun. 2005 Sep;6(6):528-38. Erratum in: Genes Immun. 2006 Mar;7(2):184.


Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity.

Koza RA, Flurkey K, Graunke DM, Braun C, Pan HJ, Reifsnyder PC, Kozak LP, Leiter EH.

Metabolism. 2004 Jun;53(6):799-808.


Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes.

Leiter EH, Reifsnyder PC.

Diabetes. 2004 Feb;53 Suppl 1:S4-11. Review.


Caspase-1 is not required for type 1 diabetes in the NOD mouse.

Schott WH, Haskell BD, Tse HM, Milton MJ, Piganelli JD, Choisy-Rossi CM, Reifsnyder PC, Chervonsky AV, Leiter EH.

Diabetes. 2004 Jan;53(1):99-104.


Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice.

Reifsnyder PC, Leiter EH.

Diabetes. 2002 Mar;51(3):825-32.


Maternal environment and genotype interact to establish diabesity in mice.

Reifsnyder PC, Churchill G, Leiter EH.

Genome Res. 2000 Oct;10(10):1568-78.


Genotypic and phenotypic characterization of six new recombinant congenic strains derived from NOD/Shi and CBA/J genomes.

Reifsnyder PC, Flynn JC, Gavin AL, Simone EA, Sharp JJ, Herberg L, Leiter EH.

Mamm Genome. 1999 Feb;10(2):161-7.


NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds.

Leiter EH, Reifsnyder PC, Flurkey K, Partke HJ, Junger E, Herberg L.

Diabetes. 1998 Aug;47(8):1287-95.


B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

Serreze DV, Chapman HD, Varnum DS, Hanson MS, Reifsnyder PC, Richard SD, Fleming SA, Leiter EH, Shultz LD.

J Exp Med. 1996 Nov 1;184(5):2049-53.


Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.

Serreze DV, Prochazka M, Reifsnyder PC, Bridgett MM, Leiter EH.

J Exp Med. 1994 Oct 1;180(4):1553-8.


Typing recombinant inbred mouse strains for microsatellite markers.

Taylor BA, Reifsnyder PC.

Mamm Genome. 1993;4(5):239-42.


Linkage of the thyroid peroxidase locus (Tpo) to markers in the proximal part of chromosome 12 of the mouse.

Taylor BA, Reifsnyder PC, DiLauro R.

Cytogenet Cell Genet. 1992;60(3-4):250-1. No abstract available.


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