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Items: 1 to 50 of 175

1.

A system for production of defective interfering particles in the absence of infectious influenza A virus.

Bdeir N, Arora P, Gärtner S, Hoffmann M, Reichl U, Pöhlmann S, Winkler M.

PLoS One. 2019 Mar 1;14(3):e0212757. doi: 10.1371/journal.pone.0212757. eCollection 2019.

2.

High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system.

Vázquez-Ramírez D, Jordan I, Sandig V, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2019 Feb 23. doi: 10.1007/s00253-019-09694-2. [Epub ahead of print]

PMID:
30796494
3.

Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions.

Rüdiger D, Kupke SY, Laske T, Zmora P, Reichl U.

PLoS Comput Biol. 2019 Feb 19;15(2):e1006819. doi: 10.1371/journal.pcbi.1006819. eCollection 2019 Feb.

4.

RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion.

Koch S, Kohrs F, Lahmann P, Bissinger T, Wendschuh S, Benndorf D, Reichl U, Klamt S.

PLoS Comput Biol. 2019 Feb 1;15(2):e1006759. doi: 10.1371/journal.pcbi.1006759. eCollection 2019 Feb.

5.

Improvement of electrospray stability in negative ion mode for nano-PGC-LC-MS glycoanalysis via post-column make-up flow.

Nguyen-Khuong T, Pralow A, Reichl U, Rapp E.

Glycoconj J. 2018 Dec;35(6):499-509. doi: 10.1007/s10719-018-9848-1. Epub 2018 Nov 23.

PMID:
30467791
6.

A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome.

Kupke SY, Riedel D, Frensing T, Zmora P, Reichl U.

J Virol. 2019 Feb 5;93(4). pii: e01786-18. doi: 10.1128/JVI.01786-18. Print 2019 Feb 15.

7.

The Fine Art of Destruction: A Guide to In-Depth Glycoproteomic Analyses-Exploiting the Diagnostic Potential of Fragment Ions.

Hoffmann M, Pioch M, Pralow A, Hennig R, Kottler R, Reichl U, Rapp E.

Proteomics. 2018 Dec;18(24):e1800282. doi: 10.1002/pmic.201800282.

PMID:
30427586
8.

glyXtoolMS: An Open-Source Pipeline for Semiautomated Analysis of Glycopeptide Mass Spectrometry Data.

Pioch M, Hoffmann M, Pralow A, Reichl U, Rapp E.

Anal Chem. 2018 Oct 16;90(20):11908-11916. doi: 10.1021/acs.analchem.8b02087. Epub 2018 Sep 25.

PMID:
30252445
9.

High-throughput Serum N-Glycomics: Method Comparison and Application to Study Rheumatoid Arthritis and Pregnancy-associated Changes.

Reiding KR, Bondt A, Hennig R, Gardner RA, O'Flaherty R, Trbojević-Akmačić I, Shubhakar A, Hazes JMW, Reichl U, Fernandes DL, Pučić-Baković M, Rapp E, Spencer DIR, Dolhain RJEM, Rudd PM, Lauc G, Wuhrer M.

Mol Cell Proteomics. 2019 Jan;18(1):3-15. doi: 10.1074/mcp.RA117.000454. Epub 2018 Sep 21.

PMID:
30242110
10.

Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production.

Nikolay A, Léon A, Schwamborn K, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2018 Oct;102(20):8725-8737. doi: 10.1007/s00253-018-9275-z. Epub 2018 Aug 8.

11.

Enzymatic Cascade Synthesis Provides Novel Linear Human Milk Oligosaccharides as Reference Standards for xCGE-LIF Based High-Throughput Analysis.

Fischöder T, Cajic S, Reichl U, Rapp E, Elling L.

Biotechnol J. 2019 Mar;14(3):e1800305. doi: 10.1002/biot.201800305. Epub 2018 Aug 23.

PMID:
30076755
12.

Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine.

Mahour R, Klapproth J, Rexer TFT, Schildbach A, Klamt S, Pietzsch M, Rapp E, Reichl U.

J Biotechnol. 2018 Oct 10;283:120-129. doi: 10.1016/j.jbiotec.2018.07.027. Epub 2018 Jul 22.

PMID:
30044949
13.

Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers.

B Carvalho S, Fortuna AR, Wolff MW, Peixoto C, M Alves P, Reichl U, Jt Carrondo M.

J Chem Technol Biotechnol. 2018 Jul;93(7):1988-1996. doi: 10.1002/jctb.5474. Epub 2017 Dec 16.

14.

High-cell-density cultivations to increase MVA virus production.

Vázquez-Ramírez D, Genzel Y, Jordan I, Sandig V, Reichl U.

Vaccine. 2018 May 24;36(22):3124-3133. doi: 10.1016/j.vaccine.2017.10.112. Epub 2018 Feb 9.

PMID:
29433897
15.

MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go.

Muth T, Kohrs F, Heyer R, Benndorf D, Rapp E, Reichl U, Martens L, Renard BY.

Anal Chem. 2018 Jan 2;90(1):685-689. doi: 10.1021/acs.analchem.7b03544. Epub 2017 Dec 19.

16.

Cell culture-based production of defective interfering particles for influenza antiviral therapy.

Wasik MA, Eichwald L, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2018 Feb;102(3):1167-1177. doi: 10.1007/s00253-017-8660-3. Epub 2017 Dec 5.

17.

Animal Cell Expression Systems.

Butler M, Reichl U.

Adv Biochem Eng Biotechnol. 2017 Oct 3. doi: 10.1007/10_2017_31. [Epub ahead of print] Erratum in: Adv Biochem Eng Biotechnol. 2018 Apr 29;:.

PMID:
29134458
18.

One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides.

Rexer TFT, Schildbach A, Klapproth J, Schierhorn A, Mahour R, Pietzsch M, Rapp E, Reichl U.

Biotechnol Bioeng. 2018 Jan;115(1):192-205. doi: 10.1002/bit.26454. Epub 2017 Oct 23.

19.

Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine.

Pralow A, Hoffmann M, Nguyen-Khuong T, Rapp E, Reichl U.

Sci Rep. 2017 Sep 12;7(1):11419. doi: 10.1038/s41598-017-11668-1.

20.

Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems.

Tapia F, Jordan I, Genzel Y, Reichl U.

PLoS One. 2017 Aug 24;12(8):e0182553. doi: 10.1371/journal.pone.0182553. eCollection 2017.

21.

Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths.

Fischer LM, Wolff MW, Reichl U.

Vaccine. 2018 May 24;36(22):3153-3160. doi: 10.1016/j.vaccine.2017.06.086. Epub 2017 Jul 17.

PMID:
28729020
22.

Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells.

Nikolay A, Castilho LR, Reichl U, Genzel Y.

Vaccine. 2018 May 24;36(22):3140-3145. doi: 10.1016/j.vaccine.2017.03.018. Epub 2017 Mar 23.

23.

Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition.

Kohrs F, Heyer R, Bissinger T, Kottler R, Schallert K, Püttker S, Behne A, Rapp E, Benndorf D, Reichl U.

Anaerobe. 2017 Aug;46:56-68. doi: 10.1016/j.anaerobe.2017.02.005. Epub 2017 Feb 9.

PMID:
28189830
24.

Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol.

Marichal-Gallardo P, Pieler MM, Wolff MW, Reichl U.

J Chromatogr A. 2016 Dec 29. pii: S0021-9673(16)31742-3. doi: 10.1016/j.chroma.2016.12.076. [Epub ahead of print]

PMID:
28089070
25.

Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol.

Marichal-Gallardo P, Pieler MM, Wolff MW, Reichl U.

J Chromatogr A. 2017 Feb 3;1483:110-119. doi: 10.1016/j.chroma.2016.12.076. Epub 2016 Dec 29.

PMID:
28069171
26.

A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection.

Pieler MM, Frentzel S, Bruder D, Wolff MW, Reichl U.

Vaccine. 2016 Dec 7;34(50):6367-6374. doi: 10.1016/j.vaccine.2016.10.041. Epub 2016 Nov 2.

PMID:
27816372
27.

Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells.

Kluge S, Genzel Y, Laus K, Serve A, Pflugmacher A, Peschel B, Rapp E, Reichl U.

Biotechnol J. 2016 Oct;11(10):1332-1342. doi: 10.1002/biot.201600384.

PMID:
27581796
28.

Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type.

Heyer R, Benndorf D, Kohrs F, De Vrieze J, Boon N, Hoffmann M, Rapp E, Schlüter A, Sczyrba A, Reichl U.

Biotechnol Biofuels. 2016 Jul 26;9:155. doi: 10.1186/s13068-016-0572-4. eCollection 2016.

29.

Early changes in the metabolic profile of activated CD8(+) T cells.

Cammann C, Rath A, Reichl U, Lingel H, Brunner-Weinzierl M, Simeoni L, Schraven B, Lindquist JA.

BMC Cell Biol. 2016 Jul 7;17(1):28. doi: 10.1186/s12860-016-0104-x.

30.

Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs.

Laske T, Heldt FS, Hoffmann H, Frensing T, Reichl U.

Virus Res. 2016 Jun 15;218:86-95. doi: 10.1016/j.virusres.2016.05.009.

PMID:
27208847
31.

Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells.

Frensing T, Kupke SY, Bachmann M, Fritzsche S, Gallo-Ramirez LE, Reichl U.

Appl Microbiol Biotechnol. 2016 Aug;100(16):7181-92. doi: 10.1007/s00253-016-7542-4. Epub 2016 Apr 29.

32.

Binding kinetics and multi-bond: Finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces.

Wang W, Voigt A, Wolff MW, Reichl U, Sundmacher K.

Anal Biochem. 2016 Jul 15;505:8-17. doi: 10.1016/j.ab.2016.04.002. Epub 2016 Apr 20.

PMID:
27108189
33.

Metaproteomics Applied to Activated Sludge for Industrial Wastewater Treatment Revealed a Dominant Methylotrophic Metabolism of Hyphomicrobium zavarzinii.

Salerno C, Benndorf D, Kluge S, Palese LL, Reichl U, Pollice A.

Microb Ecol. 2016 Jul;72(1):9-13. doi: 10.1007/s00248-016-0769-x. Epub 2016 Apr 18.

PMID:
27090901
34.

Towards personalized diagnostics via longitudinal study of the human plasma N-glycome.

Hennig R, Cajic S, Borowiak M, Hoffmann M, Kottler R, Reichl U, Rapp E.

Biochim Biophys Acta. 2016 Aug;1860(8):1728-38. doi: 10.1016/j.bbagen.2016.03.035. Epub 2016 Mar 31.

35.

Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand.

Meininger M, Stepath M, Hennig R, Cajic S, Rapp E, Rotering H, Wolff MW, Reichl U.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 15;1012-1013:193-203. doi: 10.1016/j.jchromb.2016.01.005. Epub 2016 Jan 11.

36.

Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process.

Koch S, Benndorf D, Fronk K, Reichl U, Klamt S.

Biotechnol Biofuels. 2016 Jan 22;9:17. doi: 10.1186/s13068-016-0429-x. eCollection 2016.

37.

Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG).

Thiesler CT, Cajic S, Hoffmann D, Thiel C, van Diepen L, Hennig R, Sgodda M, Weiβmann R, Reichl U, Steinemann D, Diekmann U, Huber NM, Oberbeck A, Cantz T, Kuss AW, Körner C, Schambach A, Rapp E, Buettner FF.

Mol Cell Proteomics. 2016 Apr;15(4):1435-52. doi: 10.1074/mcp.M115.054122. Epub 2016 Jan 19.

38.

Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production.

Tapia F, Vázquez-Ramírez D, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2016 Mar;100(5):2121-32. doi: 10.1007/s00253-015-7267-9. Epub 2016 Jan 13. Review.

39.

A membrane-based purification process for cell culture-derived influenza A virus.

Weigel T, Solomaier T, Wehmeyer S, Peuker A, Wolff MW, Reichl U.

J Biotechnol. 2016 Feb 20;220:12-20. doi: 10.1016/j.jbiotec.2015.12.022. Epub 2015 Dec 19.

PMID:
26712479
40.

Impaired antiviral response of adenovirus-transformed cell lines supports virus replication.

Bachmann M, Breitwieser T, Lipps C, Wirth D, Jordan I, Reichl U, Frensing T.

J Gen Virol. 2016 Feb;97(2):293-8. doi: 10.1099/jgv.0.000361. Epub 2015 Dec 8.

PMID:
26647282
41.

Site-specific O-Glycosylation Analysis of Human Blood Plasma Proteins.

Hoffmann M, Marx K, Reichl U, Wuhrer M, Rapp E.

Mol Cell Proteomics. 2016 Feb;15(2):624-41. doi: 10.1074/mcp.M115.053546. Epub 2015 Nov 23.

42.

Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs.

Laske T, Heldt FS, Hoffmann H, Frensing T, Reichl U.

Virus Res. 2016 Feb 2;213:90-99. doi: 10.1016/j.virusres.2015.11.016. Epub 2015 Nov 23.

PMID:
26592173
43.

Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection.

Heldt FS, Kupke SY, Dorl S, Reichl U, Frensing T.

Nat Commun. 2015 Nov 20;6:8938. doi: 10.1038/ncomms9938.

44.

Comparison of Influenza Virus Particle Purification Using Magnetic Sulfated Cellulose Particles with an Established Centrifugation Method for Analytics.

Serve A, Pieler MM, Benndorf D, Rapp E, Wolff MW, Reichl U.

Anal Chem. 2015 Nov 3;87(21):10708-11. doi: 10.1021/acs.analchem.5b02681. Epub 2015 Oct 14.

PMID:
26447768
45.

Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.

Karsten CB, Buettner FF, Cajic S, Nehlmeier I, Neumann B, Klippert A, Sauermann U, Reichl U, Gerardy-Schahn R, Rapp E, Stahl-Hennig C, Pöhlmann S.

J Virol. 2015 Nov;89(22):11727-33. doi: 10.1128/JVI.01358-15. Epub 2015 Sep 9.

46.

Colonic metaproteomic signatures of active bacteria and the host in obesity.

Kolmeder CA, Ritari J, Verdam FJ, Muth T, Keskitalo S, Varjosalo M, Fuentes S, Greve JW, Buurman WA, Reichl U, Rapp E, Martens L, Palva A, Salonen A, Rensen SS, de Vos WM.

Proteomics. 2015 Oct;15(20):3544-52. doi: 10.1002/pmic.201500049. Epub 2015 Sep 11.

PMID:
26255997
47.

Metaproteomics of activated sludge from a wastewater treatment plant - a pilot study.

Püttker S, Kohrs F, Benndorf D, Heyer R, Rapp E, Reichl U.

Proteomics. 2015 Oct;15(20):3596-601. doi: 10.1002/pmic.201400559. Epub 2015 Aug 20.

PMID:
26201837
48.

Bioreactor concepts for cell culture-based viral vaccine production.

Gallo-Ramírez LE, Nikolay A, Genzel Y, Reichl U.

Expert Rev Vaccines. 2015;14(9):1181-95. doi: 10.1586/14760584.2015.1067144. Epub 2015 Jul 15. Review.

PMID:
26178380
49.

N-Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF.

Hennig R, Rapp E, Kottler R, Cajic S, Borowiak M, Reichl U.

Methods Mol Biol. 2015;1331:123-43. doi: 10.1007/978-1-4939-2874-3_8.

PMID:
26169738
50.

Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities.

Kohrs F, Wolter S, Benndorf D, Heyer R, Hoffmann M, Rapp E, Bremges A, Sczyrba A, Schlüter A, Reichl U.

Proteomics. 2015 Oct;15(20):3585-9. doi: 10.1002/pmic.201400557. Epub 2015 Aug 12.

PMID:
26152594

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