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Items: 1 to 50 of 235

1.

Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction.

Arnold TD, Lizama CO, Cautivo KM, Santander N, Lin L, Qiu H, Huang EJ, Liu C, Mukouyama YS, Reichardt LF, Zovein AC, Sheppard D.

J Exp Med. 2019 Apr 1;216(4):900-915. doi: 10.1084/jem.20181290. Epub 2019 Mar 7.

2.

Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.

Rakotomamonjy J, Brunner M, Jüschke C, Zang K, Huang EJ, Reichardt LF, Chenn A.

Neural Dev. 2017 May 8;12(1):7. doi: 10.1186/s13064-017-0085-2.

3.

Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum.

Chen AI, Zang K, Masliah E, Reichardt LF.

Sci Rep. 2016 Feb 1;6:20201. doi: 10.1038/srep20201.

4.

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.

Arnold TD, Niaudet C, Pang MF, Siegenthaler J, Gaengel K, Jung B, Ferrero GM, Mukouyama YS, Fuxe J, Akhurst R, Betsholtz C, Sheppard D, Reichardt LF.

Development. 2014 Dec;141(23):4489-99. doi: 10.1242/dev.107193. Epub 2014 Nov 18.

5.

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.

Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL.

Sci Transl Med. 2014 Jun 18;6(241):241ra79. doi: 10.1126/scitranslmed.3008074.

6.

Pathologic fractures in bisphosphonate-related osteonecrosis of the jaw-review of the literature and review of our own cases.

Otto S, Pautke C, Hafner S, Hesse R, Reichardt LF, Mast G, Ehrenfeld M, Cornelius CP.

Craniomaxillofac Trauma Reconstr. 2013 Sep;6(3):147-54. doi: 10.1055/s-0033-1343776. Epub 2013 May 31. Review.

7.

Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons.

Unterwald EM, Page ME, Brown TB, Miller JS, Ruiz M, Pescatore KA, Xu B, Reichardt LF, Beverley J, Tang B, Steiner H, Thomas EA, Ehrlich ME.

Mol Neurodegener. 2013 Dec 26;8:47. doi: 10.1186/1750-1326-8-47.

8.

Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.

Shang Y, Doan CN, Arnold TD, Lee S, Tang AA, Reichardt LF, Huang EJ.

PLoS Biol. 2013;11(4):e1001527. doi: 10.1371/journal.pbio.1001527. Epub 2013 Apr 2.

9.

De novo lumen formation and elongation in the developing nephron: a central role for afadin in apical polarity.

Yang Z, Zimmerman S, Brakeman PR, Beaudoin GM 3rd, Reichardt LF, Marciano DK.

Development. 2013 Apr;140(8):1774-84. doi: 10.1242/dev.087957. Epub 2013 Mar 13.

10.

A novel method that improves sensitivity of protein detection in PAGE and Western blot.

Vallejo-Illarramendi A, Marciano DK, Reichardt LF.

Electrophoresis. 2013 Apr;34(8):1148-50. doi: 10.1002/elps.201200534. Epub 2013 Mar 15.

11.

Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes.

Moya PR, Dodman NH, Timpano KR, Rubenstein LM, Rana Z, Fried RL, Reichardt LF, Heiman GA, Tischfield JA, King RA, Galdzicka M, Ginns EI, Wendland JR.

Eur J Hum Genet. 2013 Aug;21(8):850-4. doi: 10.1038/ejhg.2012.245. Epub 2013 Jan 16.

12.

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex.

Beaudoin GM 3rd, Lee SH, Singh D, Yuan Y, Ng YG, Reichardt LF, Arikkath J.

Nat Protoc. 2012 Sep;7(9):1741-54. doi: 10.1038/nprot.2012.099. Epub 2012 Aug 30.

PMID:
22936216
13.

Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is critical for formation of α-smooth muscle actin filaments during myofibroblast differentiation.

Cai GQ, Chou CF, Hu M, Zheng A, Reichardt LF, Guan JL, Fang H, Luckhardt TR, Zhou Y, Thannickal VJ, Ding Q.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15;303(8):L692-702. doi: 10.1152/ajplung.00390.2011. Epub 2012 Aug 10.

14.

TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry.

Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF.

J Neurosci. 2012 Mar 21;32(12):4065-79. doi: 10.1523/JNEUROSCI.6314-11.2012.

15.

Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior.

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ.

J Neurosci. 2012 Feb 22;32(8):2824-34. doi: 10.1523/JNEUROSCI.3942-11.2012.

16.

Chronic refractory osteomyelitis as a part of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome: a diagnostic challenge.

Reichardt LF, Pitak-Arnnop P, Hemprich A, Dhanuthai K, Pausch NC.

ANZ J Surg. 2011 Sep;81(9):642-3. No abstract available.

PMID:
22295403
17.

Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.

Arnold TD, Ferrero GM, Qiu H, Phan IT, Akhurst RJ, Huang EJ, Reichardt LF.

J Neurosci. 2012 Jan 25;32(4):1197-206. doi: 10.1523/JNEUROSCI.5648-11.2012. Erratum in: J Neurosci. 2012 Apr 11;32(15):5351.

18.

Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus.

Beaudoin GM 3rd, Schofield CM, Nuwal T, Zang K, Ullian EM, Huang B, Reichardt LF.

J Neurosci. 2012 Jan 4;32(1):99-110. doi: 10.1523/JNEUROSCI.4565-11.2012.

19.

Introduction: the role of extracellular matrix in nervous system development and maintenance.

Reichardt LF, Prokop A.

Dev Neurobiol. 2011 Nov;71(11):883-8. doi: 10.1002/dneu.20975. No abstract available.

20.

p120 catenin is required for normal renal tubulogenesis and glomerulogenesis.

Marciano DK, Brakeman PR, Lee CZ, Spivak N, Eastburn DJ, Bryant DM, Beaudoin GM 3rd, Hofmann I, Mostov KE, Reichardt LF.

Development. 2011 May;138(10):2099-109. doi: 10.1242/dev.056564. Erratum in: Development. 2011 Jun;138(12):2632.

21.

TrkB (tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex.

Chen AI, Nguyen CN, Copenhagen DR, Badurek S, Minichiello L, Ranscht B, Reichardt LF.

J Neurosci. 2011 Feb 23;31(8):2769-80. doi: 10.1523/JNEUROSCI.4991-10.2011.

22.

The basement membrane of hair follicle stem cells is a muscle cell niche.

Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM.

Cell. 2011 Feb 18;144(4):577-89. doi: 10.1016/j.cell.2011.01.014.

23.

Mesangial cell integrin αvβ8 provides glomerular endothelial cell cytoprotection by sequestering TGF-β and regulating PECAM-1.

Khan S, Lakhe-Reddy S, McCarty JH, Sorenson CM, Sheibani N, Reichardt LF, Kim JH, Wang B, Sedor JR, Schelling JR.

Am J Pathol. 2011 Feb;178(2):609-20. doi: 10.1016/j.ajpath.2010.10.031.

24.

TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons.

Baydyuk M, Russell T, Liao GY, Zang K, An JJ, Reichardt LF, Xu B.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1669-74. doi: 10.1073/pnas.1004744108. Epub 2011 Jan 4.

25.

Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.

Ishiyama N, Lee SH, Liu S, Li GY, Smith MJ, Reichardt LF, Ikura M.

Cell. 2010 Apr 2;141(1):117-28. doi: 10.1016/j.cell.2010.01.017.

26.

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.

Wu HH, Bellmunt E, Scheib JL, Venegas V, Burkert C, Reichardt LF, Zhou Z, Fariñas I, Carter BD.

Nat Neurosci. 2009 Dec;12(12):1534-41. doi: 10.1038/nn.2446. Epub 2009 Nov 15.

27.

Retrograde neurotrophic signaling requires a protein interacting with receptor tyrosine kinases via C2H2 zinc fingers.

Fu X, Zang K, Zhou Z, Reichardt LF, Xu B.

Mol Biol Cell. 2010 Jan 1;21(1):36-49. doi: 10.1091/mbc.E09-04-0321. Epub 2009 Oct 28.

28.

Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development.

Vallejo-Illarramendi A, Zang K, Reichardt LF.

J Clin Invest. 2009 Aug;119(8):2218-30. doi: 10.1172/JCI38194. Epub 2009 Jul 1.

29.

Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity.

Shi Y, Pontrello CG, DeFea KA, Reichardt LF, Ethell IM.

J Neurosci. 2009 Jun 24;29(25):8129-42. doi: 10.1523/JNEUROSCI.4681-08.2009.

30.

Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion.

Quach NL, Biressi S, Reichardt LF, Keller C, Rando TA.

Mol Biol Cell. 2009 Jul;20(14):3422-35. doi: 10.1091/mbc.E09-02-0175. Epub 2009 May 20.

31.

Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development.

Arikkath J, Peng IF, Ng YG, Israely I, Liu X, Ullian EM, Reichardt LF.

J Neurosci. 2009 Apr 29;29(17):5435-42. doi: 10.1523/JNEUROSCI.0835-09.2009.

32.

Focal adhesion kinase (FAK): A regulator of CNS myelination.

Forrest AD, Beggs HE, Reichardt LF, Dupree JL, Colello RJ, Fuss B.

J Neurosci Res. 2009 Nov 15;87(15):3456-64. doi: 10.1002/jnr.22022.

33.

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG.

J Clin Invest. 2009 Feb;119(2):252-66. doi: 10.1172/JCI37160. Epub 2009 Jan 19.

34.

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and beta-catenin.

Lee SH, Peng IF, Ng YG, Yanagisawa M, Bamji SX, Elia LP, Balsamo J, Lilien J, Anastasiadis PZ, Ullian EM, Reichardt LF.

J Cell Biol. 2008 Dec 1;183(5):893-908. doi: 10.1083/jcb.200807188.

35.

N-Cadherin and integrins: two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces.

Reichardt LF.

Neuron. 2008 Nov 6;60(3):398-9. doi: 10.1016/j.neuron.2008.10.030. No abstract available.

36.

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity.

Arikkath J, Reichardt LF.

Trends Neurosci. 2008 Sep;31(9):487-94. doi: 10.1016/j.tins.2008.07.001. Epub 2008 Aug 4. Review.

37.

Erbin controls dendritic morphogenesis by regulating localization of delta-catenin.

Arikkath J, Israely I, Tao Y, Mei L, Liu X, Reichardt LF.

J Neurosci. 2008 Jul 9;28(28):7047-56. doi: 10.1523/JNEUROSCI.0451-08.2008.

38.

Retinal TrkB receptors regulate neural development in the inner, but not outer, retina.

Grishanin RN, Yang H, Liu X, Donohue-Rolfe K, Nune GC, Zang K, Xu B, Duncan JL, Lavail MM, Copenhagen DR, Reichardt LF.

Mol Cell Neurosci. 2008 Jul;38(3):431-43. doi: 10.1016/j.mcn.2008.04.004. Epub 2008 Apr 22.

39.

Deletion of integrin-linked kinase from skeletal muscles of mice resembles muscular dystrophy due to alpha 7 beta 1-integrin deficiency.

Gheyara AL, Vallejo-Illarramendi A, Zang K, Mei L, St-Arnaud R, Dedhar S, Reichardt LF.

Am J Pathol. 2007 Dec;171(6):1966-77. Epub 2007 Nov 30.

40.

Requirement of TrkB for synapse elimination in developing cerebellar Purkinje cells.

Bosman LW, Hartmann J, Barski JJ, Lepier A, Noll-Hussong M, Reichardt LF, Konnerth A.

Brain Cell Biol. 2006 Feb;35(1):87-101. Epub 2007 Mar 1.

41.

Methods for identifying novel integrin ligands.

Marciano DK, Denda S, Reichardt LF.

Methods Enzymol. 2007;426:223-37. Review.

42.

Studies on integrins in the nervous system.

Denda S, Reichardt LF.

Methods Enzymol. 2007;426:203-21. Review.

43.

Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice.

Travis MA, Reizis B, Melton AC, Masteller E, Tang Q, Proctor JM, Wang Y, Bernstein X, Huang X, Reichardt LF, Bluestone JA, Sheppard D.

Nature. 2007 Sep 20;449(7160):361-5. Epub 2007 Aug 12.

44.

Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina.

Liu X, Grishanin RN, Tolwani RJ, Rentería RC, Xu B, Reichardt LF, Copenhagen DR.

J Neurosci. 2007 Jul 4;27(27):7256-67.

45.

The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.

Linton JM, Martin GR, Reichardt LF.

Development. 2007 Jul;134(13):2501-9. Epub 2007 May 30.

46.

Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment.

Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM.

Mol Cell Biol. 2007 Aug;27(15):5352-64. Epub 2007 May 25.

47.

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics.

Schober M, Raghavan S, Nikolova M, Polak L, Pasolli HA, Beggs HE, Reichardt LF, Fuchs E.

J Cell Biol. 2007 Feb 26;176(5):667-80.

48.

Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse.

Huang Z, Shimazu K, Woo NH, Zang K, Müller U, Lu B, Reichardt LF.

J Neurosci. 2006 Oct 25;26(43):11208-19.

49.

Neurotrophin-regulated signalling pathways.

Reichardt LF.

Philos Trans R Soc Lond B Biol Sci. 2006 Sep 29;361(1473):1545-64. Review.

50.

Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy.

DiMichele LA, Doherty JT, Rojas M, Beggs HE, Reichardt LF, Mack CP, Taylor JM.

Circ Res. 2006 Sep 15;99(6):636-45. Epub 2006 Aug 10.

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