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Items: 1 to 50 of 240

1.

Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).

Miazzi C, Ferraro P, Pontarin G, Rampazzo C, Reichard P, Bianchi V.

J Biol Chem. 2014 Jun 27;289(26):18339-46. doi: 10.1074/jbc.M114.571091. Epub 2014 May 14.

2.

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.

Franzolin E, Pontarin G, Rampazzo C, Miazzi C, Ferraro P, Palumbo E, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14272-7. doi: 10.1073/pnas.1312033110. Epub 2013 Jul 15.

3.

Out of S-phase: shift of subunits for ribonucleotide reduction.

Pontarin G, Ferraro P, Reichard P, Bianchi V.

Cell Cycle. 2012 Nov 15;11(22):4099-100. doi: 10.4161/cc.22324. Epub 2012 Oct 17. No abstract available.

4.

Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells.

Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13302-7. doi: 10.1073/pnas.1211289109. Epub 2012 Jul 30.

5.

Deoxyribonucleotide metabolism in cycling and resting human fibroblasts with a missense mutation in p53R2, a subunit of ribonucleotide reductase.

Pontarin G, Ferraro P, Rampazzo C, Kollberg G, Holme E, Reichard P, Bianchi V.

J Biol Chem. 2011 Apr 1;286(13):11132-40. doi: 10.1074/jbc.M110.202283. Epub 2011 Feb 5.

6.

Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints.

Leanza L, Miazzi C, Ferraro P, Reichard P, Bianchi V.

Exp Cell Res. 2010 Dec 10;316(20):3443-53. doi: 10.1016/j.yexcr.2010.06.023. Epub 2010 Jul 11.

PMID:
20603113
7.

Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances.

Rampazzo C, Miazzi C, Franzolin E, Pontarin G, Ferraro P, Frangini M, Reichard P, Bianchi V.

Mutat Res. 2010 Nov 28;703(1):2-10. doi: 10.1016/j.mrgentox.2010.06.002. Epub 2010 Jun 16. Review.

PMID:
20561600
8.

Ribonucleotide reductases: substrate specificity by allostery.

Reichard P.

Biochem Biophys Res Commun. 2010 May 21;396(1):19-23. doi: 10.1016/j.bbrc.2010.02.108. Review.

PMID:
20494104
9.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

10.

Quantitation of cellular deoxynucleoside triphosphates.

Ferraro P, Franzolin E, Pontarin G, Reichard P, Bianchi V.

Nucleic Acids Res. 2010 Apr;38(6):e85. doi: 10.1093/nar/gkp1141. Epub 2009 Dec 11.

11.

Modelling the risk of Pb and PAH intervention value exceedance in allotment soils by robust logistic regression.

Papritz A, Reichard PU.

Environ Pollut. 2009 Jul;157(7):2019-22. doi: 10.1016/j.envpol.2009.02.032. Epub 2009 Mar 25.

PMID:
19321242
12.

Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.

Pontarin G, Fijolek A, Pizzo P, Ferraro P, Rampazzo C, Pozzan T, Thelander L, Reichard PA, Bianchi V.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17801-6. doi: 10.1073/pnas.0808198105. Epub 2008 Nov 7.

13.

Metabolic interrelations within guanine deoxynucleotide pools for mitochondrial and nuclear DNA maintenance.

Leanza L, Ferraro P, Reichard P, Bianchi V.

J Biol Chem. 2008 Jun 13;283(24):16437-45. doi: 10.1074/jbc.M801572200. Epub 2008 Apr 16.

14.

[Nucleic acid research--family history with two Nobel Prizes].

Lagerkvist U, Reichard P, Thelander L, Elias P.

Lakartidningen. 2008 Jan 23-29;105(4):235-6. Swedish. No abstract available.

PMID:
18306831
15.

p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage.

Pontarin G, Ferraro P, Håkansson P, Thelander L, Reichard P, Bianchi V.

J Biol Chem. 2007 Jun 8;282(23):16820-8. Epub 2007 Apr 7.

16.

Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: analysis of EORTC-ISG-AGITG study 62005.

Verweij J, Casali PG, Kotasek D, Le Cesne A, Reichard P, Judson IR, Issels R, van Oosterom AT, Van Glabbeke M, Blay JY.

Eur J Cancer. 2007 Apr;43(6):974-8. Epub 2007 Mar 2.

PMID:
17336514
17.

Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate.

Ferraro P, Nicolosi L, Bernardi P, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18586-91. Epub 2006 Nov 21.

18.

Mitochondrial DNA depletion and thymidine phosphate pool dynamics in a cellular model of mitochondrial neurogastrointestinal encephalomyopathy.

Pontarin G, Ferraro P, Valentino ML, Hirano M, Reichard P, Bianchi V.

J Biol Chem. 2006 Aug 11;281(32):22720-8. Epub 2006 Jun 13.

19.

Ribonucleotide reductases.

Nordlund P, Reichard P.

Annu Rev Biochem. 2006;75:681-706. Review.

PMID:
16756507
20.

Euglena gracilis ribonucleotide reductase: the eukaryote class II enzyme and the possible antiquity of eukaryote B12 dependence.

Torrents E, Trevisiol C, Rotte C, Hellman U, Martin W, Reichard P.

J Biol Chem. 2006 Mar 3;281(9):5604-11. Epub 2005 Dec 19.

21.

Mitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).

Ferraro P, Pontarin G, Crocco L, Fabris S, Reichard P, Bianchi V.

J Biol Chem. 2005 Jul 1;280(26):24472-80. Epub 2005 May 5.

22.

Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase.

Larsson KM, Jordan A, Eliasson R, Reichard P, Logan DT, Nordlund P.

Nat Struct Mol Biol. 2004 Nov;11(11):1142-9. Epub 2004 Oct 10.

PMID:
15475969
23.

Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors.

Rinaldo-Matthis A, Rampazzo C, Balzarini J, Reichard P, Bianchi V, Nordlund P.

Mol Pharmacol. 2004 Apr;65(4):860-7.

PMID:
15044615
24.

Mitochondrial deoxyribonucleotides, pool sizes, synthesis, and regulation.

Rampazzo C, Ferraro P, Pontarin G, Fabris S, Reichard P, Bianchi V.

J Biol Chem. 2004 Apr 23;279(17):17019-26. Epub 2004 Jan 26.

25.

Origins of mitochondrial thymidine triphosphate: dynamic relations to cytosolic pools.

Pontarin G, Gallinaro L, Ferraro P, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12159-64. Epub 2003 Sep 30.

26.

Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy.

Mazzon C, Rampazzo C, Scaini MC, Gallinaro L, Karlsson A, Meier C, Balzarini J, Reichard P, Bianchi V.

Biochem Pharmacol. 2003 Aug 1;66(3):471-9.

PMID:
12907246
27.
28.

Crystal structure of a human mitochondrial deoxyribonucleotidase.

Rinaldo-Matthis A, Rampazzo C, Reichard P, Bianchi V, Nordlund P.

Nat Struct Biol. 2002 Oct;9(10):779-87.

PMID:
12352955
29.

Human mitochondrial 5'-deoxyribonucleotidase. Overproduction in cultured cells and functional aspects.

Gallinaro L, Crovatto K, Rampazzo C, Pontarin G, Ferraro P, Milanesi E, Reichard P, Bianchi V.

J Biol Chem. 2002 Sep 20;277(38):35080-7. Epub 2002 Jul 17.

30.

5'-Nucleotidases: specific assays for five different enzymes in cell extracts.

Rampazzo C, Mazzon C, Reichard P, Bianchi V.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):258-63.

PMID:
12054593
31.

High gastric output as a perioperative sign of carcinoid syndrome.

Pandharipande PP, Reichard PS, Vallee MF.

Anesthesiology. 2002 Mar;96(3):755-6. No abstract available.

PMID:
11873054
32.

Osvald T. Avery and the Nobel Prize in medicine.

Reichard P.

J Biol Chem. 2002 Apr 19;277(16):13355-62. Epub 2002 Feb 28. No abstract available.

33.

Ribonucleotide reductases: the evolution of allosteric regulation.

Reichard P.

Arch Biochem Biophys. 2002 Jan 15;397(2):149-55. Review.

PMID:
11795865
34.

The anaerobic ribonucleotide reductase from Lactococcus lactis. Interactions between the two proteins NrdD and NrdG.

Torrents E, Eliasson R, Wolpher H, Gräslund A, Reichard P.

J Biol Chem. 2001 Sep 7;276(36):33488-94. Epub 2001 Jun 26.

35.

Autonomic neuropathy--a complication less pronounced in patients with Type 1 diabetes mellitus who have lower blood glucose levels.

Reichard P, Jensen-Urstad K, Ericsson M, Jensen-Urstad M, Lindblad LE.

Diabet Med. 2000 Dec;17(12):860-6.

PMID:
11168329
36.

Cytosolic high K(m) 5'-nucleotidase and 5'(3')-deoxyribonucleotidase in substrate cycles involved in nucleotide metabolism.

Gazziola C, Ferraro P, Moras M, Reichard P, Bianchi V.

J Biol Chem. 2001 Mar 2;276(9):6185-90. Epub 2000 Nov 16.

37.

A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease.

Rampazzo C, Gallinaro L, Milanesi E, Frigimelica E, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8239-44.

38.

Cross-talk between the allosteric effector-binding sites in mouse ribonucleotide reductase.

Reichard P, Eliasson R, Ingemarson R, Thelander L.

J Biol Chem. 2000 Oct 20;275(42):33021-6.

39.

The active form of the R2F protein of class Ib ribonucleotide reductase from Corynebacterium ammoniagenes is a diferric protein.

Huque Y, Fieschi F, Torrents E, Gibert I, Eliasson R, Reichard P, Sahlin M, Sjoberg BM.

J Biol Chem. 2000 Aug 18;275(33):25365-71.

40.

Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells.

Rampazzo C, Johansson M, Gallinaro L, Ferraro P, Hellman U, Karlsson A, Reichard P, Bianchi V.

J Biol Chem. 2000 Feb 25;275(8):5409-15.

41.

The anaerobic (class III) ribonucleotide reductase from Lactococcus lactis. Catalytic properties and allosteric regulation of the pure enzyme system.

Torrents E, Buist G, Liu A, Eliasson R, Kok J, Gibert I, Gräslund A, Reichard P.

J Biol Chem. 2000 Jan 28;275(4):2463-71.

42.

Induction of human high K(M) 5'-nucleotidase in cultured 293 cells.

Gazziola C, Moras M, Ferraro P, Gallinaro L, Verin R, Rampazzo C, Reichard P, Bianchi V.

Exp Cell Res. 1999 Dec 15;253(2):474-82.

PMID:
10585270
43.

[Letrozole (Femara), a new aromatase inhibitor for advanced breast cancer].

Gershanovich M, Chaudri Kh, Campos D, Lurie H, Bonaventura A, Jeffrey M, Buzzi F, Bodrogi I, Ludwig H, Reichard P, O'Higgins NO, Romieu G, Friedrich P, Lassus M.

Vopr Onkol. 1999;45(4):361-8. Russian.

PMID:
10532092
44.

Temporary malfunction of the Ohmeda Modulus CD series volume monitor caused by the overhead surgical lighting.

Sattari R, Reichard PS.

Anesthesiology. 1999 Sep;91(3):894-5. No abstract available.

PMID:
10485811
45.

Ribonucleotide reduction in Pseudomonas species: simultaneous presence of active enzymes from different classes.

Jordan A, Torrents E, Sala I, Hellman U, Gibert I, Reichard P.

J Bacteriol. 1999 Jul;181(13):3974-80.

46.

[Rules of Tove Jansson serve as guidance for physicians].

Reichard P.

Lakartidningen. 1999 May 5;96(18):2265. Swedish. No abstract available.

PMID:
10377670
47.

Human high-Km 5'-nucleotidase effects of overexpression of the cloned cDNA in cultured human cells.

Rampazzo C, Gazziola C, Ferraro P, Gallinaro L, Johansson M, Reichard P, Bianchi V.

Eur J Biochem. 1999 May;261(3):689-97.

48.

Decreased heart rate variability in patients with type 1 diabetes mellitus is related to arterial wall stiffness.

Jensen-Urstad K, Reichard P, Jensen-Urstad M.

J Intern Med. 1999 Jan;245(1):57-61.

49.
50.

[Intensified insulin treatment is cost-effective].

Reichard P, Alm C, Andersson E, Wärn I, Rosenqvist U.

Lakartidningen. 1999 Jan 20;96(3):172-4. Review. Swedish.

PMID:
9951231

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