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Items: 18


An occupational exposure limit (OEL) approach to protect home healthcare workers exposed to common nebulized drugs.

Frank E, Ishau S, Maier A, Reutman S, Reichard JF.

Regul Toxicol Pharmacol. 2019 Aug;106:251-261. doi: 10.1016/j.yrtph.2019.04.021. Epub 2019 Apr 29.


The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A.

Cell Syst. 2018 Jan 24;6(1):13-24. doi: 10.1016/j.cels.2017.11.001. Epub 2017 Nov 29. Review.


Mode-of-action evaluation for the effect of trans fatty acids on low-density lipoprotein cholesterol.

Reichard JF, Haber LT.

Food Chem Toxicol. 2016 Dec;98(Pt B):282-294. doi: 10.1016/j.fct.2016.05.018. Epub 2016 May 27.


Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals.

Reichard JF, Maier MA, Naumann BD, Pecquet AM, Pfister T, Sandhu R, Sargent EV, Streeter AJ, Weideman PA.

Regul Toxicol Pharmacol. 2016 Aug;79 Suppl 1:S67-78. doi: 10.1016/j.yrtph.2016.05.027. Epub 2016 May 22. Review.


Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.

Budinsky RA, Schrenk D, Simon T, Van den Berg M, Reichard JF, Silkworth JB, Aylward LL, Brix A, Gasiewicz T, Kaminski N, Perdew G, Starr TB, Walker NJ, Rowlands JC.

Crit Rev Toxicol. 2014 Jan;44(1):83-119. doi: 10.3109/10408444.2013.835787. Epub 2013 Nov 19. Review.


Arsenic toxicology: translating between experimental models and human pathology.

States JC, Barchowsky A, Cartwright IL, Reichard JF, Futscher BW, Lantz RC.

Environ Health Perspect. 2011 Oct;119(10):1356-63. doi: 10.1289/ehp.1103441. Epub 2011 Jun 17. Review.


Effects of arsenic exposure on DNA methylation and epigenetic gene regulation.

Reichard JF, Puga A.

Epigenomics. 2010 Feb;2(1):87-104. doi: 10.2217/epi.09.45. Review.


Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs.

Sartor MA, Schnekenburger M, Marlowe JL, Reichard JF, Wang Y, Fan Y, Ma C, Karyala S, Halbleib D, Liu X, Medvedovic M, Puga A.

Environ Health Perspect. 2009 Jul;117(7):1139-46. doi: 10.1289/ehp.0800485. Epub 2009 Mar 24.


Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor.

Reichard JF, Dalton TP, Shertzer HG, Puga A.

Dose Response. 2006 May 1;3(3):306-31. doi: 10.2203/dose-response.003.03.003.


BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite.

Reichard JF, Sartor MA, Puga A.

J Biol Chem. 2008 Aug 15;283(33):22363-70. doi: 10.1074/jbc.M801784200. Epub 2008 Jun 11.


Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1.

Reichard JF, Motz GT, Puga A.

Nucleic Acids Res. 2007;35(21):7074-86. Epub 2007 Oct 16.


Long term low-dose arsenic exposure induces loss of DNA methylation.

Reichard JF, Schnekenburger M, Puga A.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):188-92. Epub 2006 Nov 10.


Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.

Kann S, Estes C, Reichard JF, Huang MY, Sartor MA, Schwemberger S, Chen Y, Dalton TP, Shertzer HG, Xia Y, Puga A.

Toxicol Sci. 2005 Oct;87(2):365-84. Epub 2005 Jul 13.


Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes.

Kann S, Huang MY, Estes C, Reichard JF, Sartor MA, Xia Y, Puga A.

Mol Pharmacol. 2005 Aug;68(2):336-46. Epub 2005 May 13.


Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate.

Reichard JF, Petersen DR.

Biochem Biophys Res Commun. 2004 Sep 24;322(3):842-53.


Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal.

Reichard JF, Doorn JA, Simon F, Taylor MS, Petersen DR.

Arch Biochem Biophys. 2003 Mar 15;411(2):243-50.


Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver.

Reichard JF, Vasiliou V, Petersen DR.

Biochim Biophys Acta. 2000 Sep 27;1487(2-3):222-32.


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