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Novel N-Acyl-1H-imidazole-1-carbothioamides: Design, Synthesis, Biological and Computational studies.

Aziz H, Saeed A, Khan MA, Afridi S, Jabeen F, Rehman AU, Hashim M.

Chem Biodivers. 2020 Jan 15. doi: 10.1002/cbdv.201900509. [Epub ahead of print]


IL1R2 Blockade Suppresses Breast Tumorigenesis and Progression by Impairing USP15-Dependent BMI1 Stability.

Zhang L, Qiang J, Yang X, Wang D, Rehman AU, He X, Chen W, Sheng D, Zhou L, Jiang YZ, Li T, Du Y, Feng J, Hu X, Zhang J, Hu XC, Shao ZM, Liu S.

Adv Sci (Weinh). 2019 Nov 13;7(1):1901728. doi: 10.1002/advs.201901728. eCollection 2020 Jan.


The Arabidopsis Nodulin Homeobox Factor AtNDX Interacts with AtRING1A/B and Negatively Regulates Abscisic Acid Signaling.

Zhu Y, Hu X, Duan Y, Li S, Wang Y, Rehman AU, He J, Zhang J, Hua D, Yang L, Wang L, Chen Z, Li C, Wang B, Song CP, Sun Q, Yang S, Gong Z.

Plant Cell. 2020 Jan 9. pii: tpc.00604.2019. doi: 10.1105/tpc.19.00604. [Epub ahead of print]


Size-Based Sorting of Emulsion Droplets in Microfluidic Channels Patterned with Laser-Ablated Guiding Tracks.

Rehman AU, Coskun UC, Rashid Z, Morova B, Jonáš A, Erten A, Kiraz A.

Anal Chem. 2020 Jan 17. doi: 10.1021/acs.analchem.9b04308. [Epub ahead of print]


Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: A proof of concept study.

Mir M, Permana AD, Ahmed N, Khan GM, Rehman AU, Donnelly RF.

Eur J Pharm Biopharm. 2020 Feb;147:57-68. doi: 10.1016/j.ejpb.2019.12.008. Epub 2019 Dec 27.


Exploring the Genetic Landscape of Retinal Diseases in North-Western Pakistan Reveals a High Degree of Autozygosity and a Prevalent Founder Mutation in ABCA4.

Rehman AU, Peter VG, Quinodoz M, Rashid A, Khan SA, Superti-Furga A, Rivolta C.

Genes (Basel). 2019 Dec 21;11(1). pii: E12. doi: 10.3390/genes11010012.


Phenolic Compounds with Antioxidant Properties from Canola Meal Extracts Inhibit Adipogenesis.

Hussain S, Rehman AU, Luckett DJ, Blanchard CL, Obied HK, Strappe P.

Int J Mol Sci. 2019 Dec 18;21(1). pii: E1. doi: 10.3390/ijms21010001.


In-silico design of peptide inhibitors of K-Ras target in cancer disease.

Ghufran M, Rehman AU, Shah M, Ayaz M, Ng HL, Wadood A.

J Biomol Struct Dyn. 2019 Dec 23:1-12. doi: 10.1080/07391102.2019.1704880. [Epub ahead of print]


Laboratory Evolution of GH11 Endoxylanase Through DNA Shuffling: Effects of Distal Residue Substitution on Catalytic Activity and Active Site Architecture.

Liu MQ, Li JY, Rehman AU, Xu X, Gu ZJ, Wu RC.

Front Bioeng Biotechnol. 2019 Nov 22;7:350. doi: 10.3389/fbioe.2019.00350. eCollection 2019.


Parvimonas micra bacteremia in a patient with colonic carcinoma.

Khan MS, Ishaq M, Hinson M, Potugari B, Rehman AU.

Caspian J Intern Med. 2019 Fall;10(4):472-475. doi: 10.22088/cjim.10.4.472.


In vitro assessment of antibacterial, antifungal, enzyme inhibition and hemolytic activities of various fractions of Rhynchosia pseudo-cajan.

Abbasi MA, Irshad M, Rehman AU, Riaz T, Siddiqui SZ, Shahid M.

Pak J Pharm Sci. 2019 Sep;32(5):2003-2010.


Synthesis of some new N-(alkyl/aralkyl)-N-(4-methoxyphenethyl) benzene sulfonamides as antibacterial agents against Escherichia.

Abbasi MA, Fatima Z, Rehman AU, Siddiqui SZ, Ali Shah SA, Shahid M, Fatima H.

Pak J Pharm Sci. 2019 Sep;32(5):1957-1964.


Growth Performance of Broilers as Influenced by Different Levels and Sources of Methionine Plus Cysteine.

Rehman AU, Arif M, Husnain MM, Alagawany M, Abd El-Hack ME, Taha AE, Elnesr SS, Abdel-Latif MA, Othman SI, Allam AA.

Animals (Basel). 2019 Dec 1;9(12). pii: E1056. doi: 10.3390/ani9121056.


A de novo variant in the human HIST1H4J gene causes a syndrome analogous to the HIST1H4C-associated neurodevelopmental disorder.

Tessadori F, Rehman AU, Giltay JC, Xia F, Streff H, Duran K, Bakkers J, Lalani SR, van Haaften G.

Eur J Hum Genet. 2019 Dec 5. doi: 10.1038/s41431-019-0552-9. [Epub ahead of print]


A Single Coronary Artery with an Absent Right Coronary and a Superdominant Left Circumflex Giving off a Branch Supplying the Right Coronary Artery Territory.

Iftikhar I, Rehman AU, Khan HS.

J Coll Physicians Surg Pak. 2019 Dec;29(12):S80-S82. doi: 10.29271/jcpsp.2019.12.S80.


Enhancement in Site-Specific Delivery of Carvacrol against Methicillin Resistant Staphylococcus aureus Induced Skin Infections Using Enzyme Responsive Nanoparticles: A Proof of Concept Study.

Mir M, Ahmed N, Permana AD, Rodgers AM, Donnelly RF, Rehman AU.

Pharmaceutics. 2019 Nov 13;11(11). pii: E606. doi: 10.3390/pharmaceutics11110606.


The Association between Iron-deficiency Anemia and Adverse Pregnancy Outcomes: A Retrospective Report from Pakistan.

Mahmood T, Rehman AU, Tserenpil G, Siddiqui F, Ahmed M, Siraj F, Kumar B.

Cureus. 2019 Oct 7;11(10):e5854. doi: 10.7759/cureus.5854.


Synthesis, in vitro α-amylase inhibitory, and radicals (DPPH & ABTS) scavenging potentials of new N-sulfonohydrazide substituted indazoles.

Rafique R, Khan KM, Arshia, Chigurupati S, Wadood A, Rehman AU, Salar U, Venugopal V, Shamim S, Taha M, Perveen S.

Bioorg Chem. 2020 Jan;94:103410. doi: 10.1016/j.bioorg.2019.103410. Epub 2019 Oct 31.


Allosteric Modulation of Intrinsically Disordered Proteins.

Rehman AU, Rahman MU, Arshad T, Chen HF.

Adv Exp Med Biol. 2019;1163:335-357. doi: 10.1007/978-981-13-8719-7_14. Review.


Molecular engineering of polymeric carbon nitride based Donor-Acceptor conjugated copolymers for enhanced photocatalytic full water splitting.

Hayat A, Shaishta N, Mane SKB, Hayat A, Khan J, Rehman AU, Li T.

J Colloid Interface Sci. 2020 Feb 15;560:743-754. doi: 10.1016/j.jcis.2019.10.088. Epub 2019 Oct 24.


Application of biological and single-strand conformation polymorphism assays for characterizing potential mild isolates of Citrus tristeza virus for cross protection.

Atta S, Umar UUD, Bashir MA, Hannan A, Rehman AU, Naqvi SAH, Zhou C.

AMB Express. 2019 Oct 31;9(1):174. doi: 10.1186/s13568-019-0903-5.


Whole-exome sequencing in a consanguineous Pakistani family identifies a mutational hotspot in the COL7A1 gene, causing recessive dystrophic epidermolysis bullosa.

Rehman AU, Peter VG, Quinodoz M, Dawood M, Rivolta C.

Clin Dysmorphol. 2019 Oct 17. doi: 10.1097/MCD.0000000000000299. [Epub ahead of print]


A Quality of Service-Aware Secured Communication Scheme for Internet of Things-Based Networks.

Khan F, Rehman AU, Yahya A, Jan MA, Chuma J, Tan Z, Hussain K.

Sensors (Basel). 2019 Oct 6;19(19). pii: E4321. doi: 10.3390/s19194321.


The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature.

Rehman AU, Hassali MAA, Muhammad SA, Harun SN, Shah S, Abbas S.

Eur J Health Econ. 2019 Sep 28. doi: 10.1007/s10198-019-01119-1. [Epub ahead of print]


Mutation, methylation and expression analysis of LIFR gene in Indian breast cancer patients.

Real SAS, Parveen F, Rehman AU, Shaik R, Deo SVS, Husain SA.

Mutat Res. 2019 Nov;816-818:111677. doi: 10.1016/j.mrfmmm.2019.111677. Epub 2019 Aug 12.


New triazinoindole bearing thiazole/oxazole analogues: Synthesis, α-amylase inhibitory potential and molecular docking study.

Rahim F, Tariq S, Taha M, Ullah H, Zaman K, Uddin I, Wadood A, Khan AA, Rehman AU, Uddin N, Zafar S, Shah SAA.

Bioorg Chem. 2019 Nov;92:103284. doi: 10.1016/j.bioorg.2019.103284. Epub 2019 Sep 17.


Impact of Premature Greying of Hair on Socio-cultural Adjustment and Self-esteem among Medical Undergraduates in Foundation University, Islamabad.

Saad M, Babar NF, Majeed R, Rehman AU, Khan OA, Chatha DE, Aamir U, Nadeem A, Abbas S.

Cureus. 2019 Jul 4;11(7):e5083. doi: 10.7759/cureus.5083.


Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking, and kinetic studies.

Hameed S, Kanwal, Seraj F, Rafique R, Chigurupati S, Wadood A, Rehman AU, Venugopal V, Salar U, Taha M, Khan KM.

Eur J Med Chem. 2019 Dec 1;183:111677. doi: 10.1016/j.ejmech.2019.111677. Epub 2019 Sep 5.


Engineering the metabolic pathways of lipid biosynthesis to develop robust microalgal strains for biodiesel production.

Shahid A, Rehman AU, Usman M, Ashraf MUF, Javed MR, Khan AZ, Gill SS, Mehmood MA.

Biotechnol Appl Biochem. 2019 Sep 5. doi: 10.1002/bab.1812. [Epub ahead of print] Review.


Redox-Mediated Endocytosis of a Receptor-Like Kinase during Distal Stem Cell Differentiation Depends on Its Tumor Necrosis Factor Receptor Domain.

Qin Y, Yang L, Sun Z, Wang X, Wang Y, Zhang J, Rehman AU, Chen Z, Qi J, Wang B, Song C, Yang S, Gong Z.

Plant Physiol. 2019 Nov;181(3):1075-1095. doi: 10.1104/pp.19.00616. Epub 2019 Aug 30.


Synthesis of new indazole based dual inhibitors of α-glucosidase and α-amylase enzymes, their in vitro, in silico and kinetics studies.

Rafique R, Khan KM, Arshia, Kanwal, Chigurupati S, Wadood A, Rehman AU, Karunanidhi A, Hameed S, Taha M, Al-Rashida M.

Bioorg Chem. 2020 Jan;94:103195. doi: 10.1016/j.bioorg.2019.103195. Epub 2019 Aug 23.


Role of purinergic receptors in hepatobiliary carcinoma in Pakistani population: an approach towards proinflammatory role of P2X4 and P2X7 receptors.

Asif A, Khalid M, Manzoor S, Ahmad H, Rehman AU.

Purinergic Signal. 2019 Sep;15(3):367-374. doi: 10.1007/s11302-019-09675-0. Epub 2019 Aug 10.


Optical Coherence Tomography-guided Intervention in STEMI Patients with Normal Looking Coronaries.

Iftikhar I, Khan HS, Yaqoob N, Rehman AU.

J Coll Physicians Surg Pak. 2019 Aug;29(8):771-774. doi: 10.29271/jcpsp.2019.08.771.


Natural compounds from plants controlling leishmanial growth via DNA damage and inhibiting trypanothione reductase and trypanothione synthetase: an in vitro and in silico approach.

Mehwish S, Khan H, Rehman AU, Khan AU, Khan MA, Hayat O, Ahmad M, Wadood A, Ullah N.

3 Biotech. 2019 Aug;9(8):303. doi: 10.1007/s13205-019-1826-1. Epub 2019 Jul 23.


Enhancing Oxygen Reduction Reaction Activity and CO2 Tolerance of Cathode for Low-Temperature Solid Oxide Fuel Cells by in Situ Formation of Carbonates.

Rehman AU, Li M, Knibbe R, Khan MS, Peterson VK, Brand HEA, Li Z, Zhou W, Zhu Z.

ACS Appl Mater Interfaces. 2019 Jul 31;11(30):26909-26919. doi: 10.1021/acsami.9b07668. Epub 2019 Jul 16.


Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol.

Shehzadi N, Hussain K, Islam M, Bukhari NI, Khan MT, Salman M, Siddiqui SZ, Rehman AU, Abbasi MA.

Acta Pharm. 2018 Dec 1;68(4):409-424. doi: 10.2478/acph-2018-0036.


Strontium-doped lanthanum iron nickelate oxide as highly efficient electrocatalysts for oxygen evolution reaction.

Li M, Insani AR, Zhuang L, Wang Z, Rehman AU, Liu LX, Zhu Z.

J Colloid Interface Sci. 2019 Oct 1;553:813-819. doi: 10.1016/j.jcis.2019.06.054. Epub 2019 Jun 17.


A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy.

Nikopoulos K, Cisarova K, Quinodoz M, Koskiniemi-Kuendig H, Miyake N, Farinelli P, Rehman AU, Khan MI, Prunotto A, Akiyama M, Kamatani Y, Terao C, Miya F, Ikeda Y, Ueno S, Fuse N, Murakami A, Wada Y, Terasaki H, Sonoda KH, Ishibashi T, Kubo M, Cremers FPM, Kutalik Z, Matsumoto N, Nishiguchi KM, Nakazawa T, Rivolta C.

Nat Commun. 2019 Jun 28;10(1):2884. doi: 10.1038/s41467-019-10746-4.


Gain-of-Function SHP2 E76Q Mutant Rescuing Autoinhibition Mechanism Associated with Juvenile Myelomonocytic Leukemia.

Rehman AU, Rafiq H, Rahman MU, Li J, Liu H, Luo S, Arshad T, Wadood A, Chen HF.

J Chem Inf Model. 2019 Jul 22;59(7):3229-3239. doi: 10.1021/acs.jcim.9b00353. Epub 2019 Jun 20.


Author Correction: Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.

Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, O'Driscoll M, Morton JEV; DDD study, Hou X, Wu Q, Tong Q, Liu Z, Liu P, Xu Y, Sun Z.

Nat Neurosci. 2019 Sep;22(9):1533. doi: 10.1038/s41593-019-0449-5.


Synthesis, in vitro urease inhibitory potential and molecular docking study of Benzimidazole analogues.

Zaman K, Rahim F, Taha M, Ullah H, Wadood A, Nawaz M, Khan F, Wahab Z, Shah SAA, Rehman AU, Kawde AN, Gollapalli M.

Bioorg Chem. 2019 Aug;89:103024. doi: 10.1016/j.bioorg.2019.103024. Epub 2019 May 31.


Immunoinformatics and structural vaccinology driven prediction of multi-epitope vaccine against Mayaro virus and validation through in-silico expression.

Khan S, Khan A, Rehman AU, Ahmad I, Ullah S, Khan AA, Ali SS, Afridi SG, Wei DQ.

Infect Genet Evol. 2019 Sep;73:390-400. doi: 10.1016/j.meegid.2019.06.006. Epub 2019 Jun 4.


Ligand decorated chitosan as an advanced nanocarrier for targeted delivery: a critical review.

Qindeel M, Ahmed N, Khan GM, Rehman AU.

Nanomedicine (Lond). 2019 Jun;14(12):1623-1642. doi: 10.2217/nnm-2018-0490. Epub 2019 Jun 5.


Structural and free energy landscape of novel mutations in ribosomal protein S1 (rpsA) associated with pyrazinamide resistance.

Khan MT, Khan A, Rehman AU, Wang Y, Akhtar K, Malik SI, Wei DQ.

Sci Rep. 2019 May 16;9(1):7482. doi: 10.1038/s41598-019-44013-9.


Surgical Outcomes of Idiopathic Macular Epiretinal Membrane Peeling.

Haseeb U, Rehman AU, Memon AF, Haseeb M, Memon N.

J Coll Physicians Surg Pak. 2019 Mar;29(3):245-248. doi: 10.29271/jcpsp.2019.03.245.


Exploring the Pyrazinamide Drug Resistance Mechanism of Clinical Mutants T370P and W403G in Ribosomal Protein S1 of Mycobacterium tuberculosis.

Rehman AU, Khan MT, Liu H, Wadood A, Malik SI, Chen HF.

J Chem Inf Model. 2019 Apr 22;59(4):1584-1597. doi: 10.1021/acs.jcim.8b00956. Epub 2019 Mar 12.


Elastic layered rubber-graphene composite fabricated by rubbing-in technology for the multi-functional sensors.

Karimov KS, Ahmad Z, Khan MI, Siddiqui KJ, Qasuria TA, Abbas SZ, Usman M, Rehman AU.

Heliyon. 2019 Jan 31;5(1):e01187. doi: 10.1016/j.heliyon.2019.e01187. eCollection 2019 Jan.


Zinc binding regulates amyloid-like aggregation of GAPR-1.

Sheng J, Olrichs NK, Geerts WJ, Li X, Rehman AU, Gadella BM, Kaloyanova DV, Helms JB.

Biosci Rep. 2019 Feb 12;39(2). pii: BSR20182345. doi: 10.1042/BSR20182345. Print 2019 Feb 28.


Prevalence of paratuberculosis in water buffaloes on public livestock farms of Punjab, Pakistan.

Rehman AU, Javed MT, Aslam MS, Khan MN, Hussain SM, Ashfaq K, Rafique A.

Vet Ital. 2018 Dec 31;54(4):887-892. doi: 10.12834/10.12834/VetIt.852.4241.1.


Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.

Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, O'Driscoll M, Morton JEV; DDD study, Hou X, Wu Q, Tong Q, Liu Z, Liu P, Xu Y, Sun Z.

Nat Neurosci. 2019 Feb;22(2):205-217. doi: 10.1038/s41593-018-0311-1. Epub 2019 Jan 21. Erratum in: Nat Neurosci. 2019 Sep;22(9):1533.

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