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Items: 11

1.

NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop.

DeFelice MM, Clark HR, Hughey JJ, Maayan I, Kudo T, Gutschow MV, Covert MW, Regot S.

Sci Signal. 2019 Apr 30;12(579). pii: eaau3568. doi: 10.1126/scisignal.aau3568.

PMID:
31040261
2.

Live-cell measurements of kinase activity in single cells using translocation reporters.

Kudo T, Jeknić S, Macklin DN, Akhter S, Hughey JJ, Regot S, Covert MW.

Nat Protoc. 2018 Jan;13(1):155-169. doi: 10.1038/nprot.2017.128. Epub 2017 Dec 21.

PMID:
29266096
3.

Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.

Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Doré LC, Jin P, Regot S, Zhuang X, Canzar S, He C, Ming GL, Song H.

Cell. 2017 Nov 2;171(4):877-889.e17. doi: 10.1016/j.cell.2017.09.003. Epub 2017 Sep 28.

4.

A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification.

de la Cova C, Townley R, Regot S, Greenwald I.

Dev Cell. 2017 Sep 11;42(5):542-553.e4. doi: 10.1016/j.devcel.2017.07.014. Epub 2017 Aug 17.

5.

Parallel feedback loops control the basal activity of the HOG MAPK signaling cascade.

Sharifian H, Lampert F, Stojanovski K, Regot S, Vaga S, Buser R, Lee SS, Koeppl H, Posas F, Pelet S, Peter M.

Integr Biol (Camb). 2015 Apr;7(4):412-22. doi: 10.1039/c4ib00299g.

PMID:
25734609
6.

High-sensitivity measurements of multiple kinase activities in live single cells.

Regot S, Hughey JJ, Bajar BT, Carrasco S, Covert MW.

Cell. 2014 Jun 19;157(7):1724-34. doi: 10.1016/j.cell.2014.04.039.

7.

Accelerated discovery via a whole-cell model.

Sanghvi JC, Regot S, Carrasco S, Karr JR, Gutschow MV, Bolival B Jr, Covert MW.

Nat Methods. 2013 Dec;10(12):1192-5. doi: 10.1038/nmeth.2724. Epub 2013 Nov 3.

8.

The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress.

Regot S, de Nadal E, Rodríguez-Navarro S, González-Novo A, Pérez-Fernandez J, Gadal O, Seisenbacher G, Ammerer G, Posas F.

J Biol Chem. 2013 Jun 14;288(24):17384-98. doi: 10.1074/jbc.M112.444042. Epub 2013 May 3. Erratum in: J Biol Chem. 2015 Jan 23;290(4):2301.

9.

Distributed biological computation with multicellular engineered networks.

Regot S, Macia J, Conde N, Furukawa K, Kjellén J, Peeters T, Hohmann S, de Nadal E, Posas F, Solé R.

Nature. 2011 Jan 13;469(7329):207-11. doi: 10.1038/nature09679. Epub 2010 Dec 8.

PMID:
21150900
10.

The HOG pathway dictates the short-term translational response after hyperosmotic shock.

Warringer J, Hult M, Regot S, Posas F, Sunnerhagen P.

Mol Biol Cell. 2010 Sep 1;21(17):3080-92. doi: 10.1091/mbc.E10-01-0006. Epub 2010 Jun 29.

11.

Dynamic signaling in the Hog1 MAPK pathway relies on high basal signal transduction.

Macia J, Regot S, Peeters T, Conde N, Solé R, Posas F.

Sci Signal. 2009 Mar 24;2(63):ra13. doi: 10.1126/scisignal.2000056.

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