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Items: 30

1.

Progranulin autoantibodies in systemic sclerosis and autoimmune connective tissue disorders: A preliminary study.

Klemm P, Assmann G, Preuss KD, Fadle N, Regitz E, Martin T, Pfreundschuh M, Thurner L.

Immun Inflamm Dis. 2019 Sep 10. doi: 10.1002/iid3.270. [Epub ahead of print]

2.

Saposin C is a frequent target of paraproteins in Gaucher disease-associated MGUS/multiple myeloma.

Preuss KD, Hollak CEM, Fadle N, van Oers M, Regitz E, Pfreundschuh M.

Br J Haematol. 2019 Feb;184(3):384-391. doi: 10.1111/bjh.15659. Epub 2018 Nov 18.

PMID:
30450574
3.

Hyper-N-glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma.

Thurner L, Preuss KD, Bewarder M, Kemele M, Fadle N, Regitz E, Altmeyer S, Schormann C, Poeschel V, Ziepert M, Walter S, Roth P, Weller M, Szczepanowski M, Klapper W, Monoranu C, Rosenwald A, Möller P, Hartmann S, Hansmann ML, Mackensen A, Schäfer H, Schorb E, Illerhaus G, Buslei R, Bohle RM, Stilgenbauer S, Kim YJ, Pfreundschuh M.

Blood. 2018 Dec 27;132(26):2744-2753. doi: 10.1182/blood-2018-03-836932. Epub 2018 Sep 24.

PMID:
30249786
4.

LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting.

Thurner L, Hartmann S, Fadle N, Kemele M, Bock T, Bewarder M, Regitz E, Neumann F, Nimmesgern A, von Müller L, Pott C, Kim YJ, Bohle RM, Wasik M, Schuster SJ, Hansmann ML, Preuss KD, Pfreundschuh M.

Leukemia. 2019 Jan;33(1):148-158. doi: 10.1038/s41375-018-0182-1. Epub 2018 Jun 28.

PMID:
29955130
5.

Autoantibodies against lamin C, NA14 and CK15 in primary vasculitides or autoimmune diseases with secondary vasculitis.

Kubuschok B, Preuss KD, Baier-Thoenes K, Regitz E, Thurner L, Assmann G, Pfreundschuh M.

Clin Exp Rheumatol. 2016 May-Jun;34(3 Suppl 97):S60-9. Epub 2016 May 19.

PMID:
27214601
6.

The molecular basis for development of proinflammatory autoantibodies to progranulin.

Thurner L, Fadle N, Regitz E, Kemele M, Klemm P, Zaks M, Stöger E, Bette B, Carbon G, Zimmer V, Assmann G, Murawski N, Kubuschok B, Held G, Preuss KD, Pfreundschuh M.

J Autoimmun. 2015 Jul;61:17-28. doi: 10.1016/j.jaut.2015.05.002. Epub 2015 May 23.

PMID:
26005049
7.

Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.

Preuss KD, Pfreundschuh M, Weigert M, Fadle N, Regitz E, Kubuschok B.

J Clin Invest. 2015 May;125(5):2179. doi: 10.1172/JCI82091. Epub 2015 May 1. No abstract available.

8.

Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.

Preuss KD, Pfreundschuh M, Weigert M, Fadle N, Regitz E, Kubuschok B.

J Clin Invest. 2015 Jan;125(1):316-23. doi: 10.1172/JCI76802. Epub 2014 Dec 8. Erratum in: J Clin Invest. 2015 May;125(5):2179. Weigert, Martin [Added].

9.

Vitamin D deficiency impairs rituximab-mediated cellular cytotoxicity and outcome of patients with diffuse large B-cell lymphoma treated with but not without rituximab.

Bittenbring JT, Neumann F, Altmann B, Achenbach M, Reichrath J, Ziepert M, Geisel J, Regitz E, Held G, Pfreundschuh M.

J Clin Oncol. 2014 Oct 10;32(29):3242-8. doi: 10.1200/JCO.2013.53.4537. Epub 2014 Aug 18.

PMID:
25135997
10.

Elevated serum free light chains do not predict outcome of elderly patients with aggressive CD20(+) B-cell lymphomas.

Achenbach M, Bittenbring JT, Ziepert M, Regitz E, Ott G, Rosenwald A, Pfreundschuh M, Altmann B, Held G.

Br J Haematol. 2014 Nov;167(3):430-4. doi: 10.1111/bjh.13001. Epub 2014 Jun 27. No abstract available.

PMID:
24974897
11.

Inactivation of protein-phosphatase 2A causing hyperphosphorylation of autoantigenic paraprotein targets in MGUS/MM is due to an exchange of its regulatory subunits.

Preuss KD, Fadle N, Regitz E, Held G, Pfreundschuh M.

Int J Cancer. 2014 Nov 1;135(9):2046-53. doi: 10.1002/ijc.28864. Epub 2014 Apr 5.

12.

Proinflammatory progranulin antibodies in inflammatory bowel diseases.

Thurner L, Stöger E, Fadle N, Klemm P, Regitz E, Kemele M, Bette B, Held G, Dauer M, Lammert F, Preuss KD, Zimmer V, Pfreundschuh M.

Dig Dis Sci. 2014 Aug;59(8):1733-42. doi: 10.1007/s10620-014-3089-3. Epub 2014 Mar 4.

PMID:
24591016
13.

Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis.

Thurner L, Zaks M, Preuss KD, Fadle N, Regitz E, Ong MF, Pfreundschuh M, Assmann G.

Arthritis Res Ther. 2013;15(6):R211.

14.

Autoantigenic targets of B-cell receptors derived from chronic lymphocytic leukemias bind to and induce proliferation of leukemic cells.

Zwick C, Fadle N, Regitz E, Kemele M, Stilgenbauer S, Bühler A, Pfreundschuh M, Preuss KD.

Blood. 2013 Jun 6;121(23):4708-17. doi: 10.1182/blood-2012-08-447904. Epub 2013 Apr 11.

15.

Progranulin antibodies in autoimmune diseases.

Thurner L, Preuss KD, Fadle N, Regitz E, Klemm P, Zaks M, Kemele M, Hasenfus A, Csernok E, Gross WL, Pasquali JL, Martin T, Bohle RM, Pfreundschuh M.

J Autoimmun. 2013 May;42:29-38. doi: 10.1016/j.jaut.2012.10.003. Epub 2012 Nov 11.

PMID:
23149338
16.

The impact of Fc-γ receptor polymorphisms in elderly patients with diffuse large B-cell lymphoma treated with CHOP with or without rituximab.

Ahlgrimm M, Pfreundschuh M, Kreuz M, Regitz E, Preuss KD, Bittenbring J.

Blood. 2011 Oct 27;118(17):4657-62. doi: 10.1182/blood-2011-04-346411. Epub 2011 Sep 7.

17.

Hyperphosphorylation of autoantigenic targets of paraproteins is due to inactivation of PP2A.

Preuss KD, Pfreundschuh M, Fadle N, Regitz E, Raudies S, Murwaski N, Ahlgrimm M, Bittenbring J, Klotz M, Schäfer KH, Held G, Neumann F, Grass S.

Blood. 2011 Sep 22;118(12):3340-6. doi: 10.1182/blood-2011-04-351668. Epub 2011 Jul 26.

18.

Paraproteins of familial MGUS/multiple myeloma target family-typical antigens: hyperphosphorylation of autoantigens is a consistent finding in familial and sporadic MGUS/MM.

Grass S, Preuss KD, Thome S, Weisenburger DD, Witt V, Lynch J, Zettl F, Trümper L, Fadle N, Regitz E, Lynch H, Pfreundschuh M.

Blood. 2011 Jul 21;118(3):635-7. doi: 10.1182/blood-2011-01-331454. Epub 2011 May 17.

19.

Hyperphosphorylated paratarg-7: a new molecularly defined risk factor for monoclonal gammopathy of undetermined significance of the IgM type and Waldenstrom macroglobulinemia.

Grass S, Preuss KD, Wikowicz A, Terpos E, Ziepert M, Nikolaus D, Yang Y, Fadle N, Regitz E, Dimopoulos MA, Treon SP, Hunter ZR, Pfreundschuh M.

Blood. 2011 Mar 10;117(10):2918-23. doi: 10.1182/blood-2010-09-306076. Epub 2011 Jan 10.

20.

Association of a dominantly inherited hyperphosphorylated paraprotein target with sporadic and familial multiple myeloma and monoclonal gammopathy of undetermined significance: a case-control study.

Grass S, Preuss KD, Ahlgrimm M, Fadle N, Regitz E, Pfoehler C, Murawski N, Pfreundschuh M.

Lancet Oncol. 2009 Oct;10(10):950-6. doi: 10.1016/S1470-2045(09)70234-7. Epub 2009 Sep 18.

PMID:
19767238
21.

A frequent target of paraproteins in the sera of patients with multiple myeloma and MGUS.

Preuss KD, Pfreundschuh M, Ahlgrimm M, Fadle N, Regitz E, Murawski N, Grass S.

Int J Cancer. 2009 Aug 1;125(3):656-61. doi: 10.1002/ijc.24427.

22.

Mitofilin and titin as target antigens in melanoma-associated retinopathy.

Pföhler C, Preuss KD, Tilgen W, Stark A, Regitz E, Fadle N, Pfreundschuh M.

Int J Cancer. 2007 Feb 15;120(4):788-95.

23.

Prospective study on the expression of cancer testis genes and antibody responses in 100 consecutive patients with primary breast cancer.

Mischo A, Kubuschok B, Ertan K, Preuss KD, Romeike B, Regitz E, Schormann C, de Bruijn D, Wadle A, Neumann F, Schmidt W, Renner C, Pfreundschuh M.

Int J Cancer. 2006 Feb 1;118(3):696-703.

24.

B-cell epitopes from the cancer testis antigen NY-ESO-1.

Preuss KD, Regitz E, Neumann F, Pfreundschuh M.

Int J Cancer. 2006 Jan 1;118(1):253. No abstract available.

25.

Expression of cancer testis antigens in pancreatic carcinoma cell lines, pancreatic adenocarcinoma and chronic pancreatitis.

Kubuschok B, Xie X, Jesnowski R, Preuss KD, Romeike BF, Neumann F, Regitz E, Pistorius G, Schilling M, Scheunemann P, Izbicki JR, Löhr JM, Pfreundschuh M.

Int J Cancer. 2004 Apr 20;109(4):568-75.

26.

Identification of an HLA-A*02 restricted immunogenic peptide derived from the cancer testis antigen HOM-MEL-40/SSX2.

Wagner C, Neumann F, Kubuschok B, Regitz E, Mischo A, Stevanovic S, Friedrich M, Schmidt W, Rammensee HG, Pfreundschuh M.

Cancer Immun. 2003 Dec 17;3:18.

27.

Recombinant antigen expression on yeast surface (RAYS) for the detection of serological immune responses in cancer patients.

Mischo A, Wadle A, Wätzig K, Jäger D, Stockert E, Santiago D, Ritter G, Regitz E, Jäger E, Knuth A, Old L, Pfreundschuh M, Renner C.

Cancer Immun. 2003 Jun 27;3:5.

28.

Differential expression of cancer testis genes in histological subtypes of non-Hodgkin's lymphomas.

Xie X, Wacker HH, Huang S, Regitz E, Preuss KD, Romeike B, Parwaresch R, Tiemann M, Pfreundschuh M.

Clin Cancer Res. 2003 Jan;9(1):167-73.

29.

Analysis of the antibody repertoire of lymphoma patients.

Huang S, Preuss KD, Xie X, Regitz E, Pfreundschuh M.

Cancer Immunol Immunother. 2002 Dec;51(11-12):655-62. Epub 2002 Oct 16.

PMID:
12439611
30.

Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas.

Schmits R, Cochlovius B, Treitz G, Regitz E, Ketter R, Preuss KD, Romeike BF, Pfreundschuh M.

Int J Cancer. 2002 Mar 1;98(1):73-7.

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