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Items: 20


DIRAS3 (ARHI) Blocks RAS/MAPK Signaling by Binding Directly to RAS and Disrupting RAS Clusters.

Sutton MN, Lu Z, Li YC, Zhou Y, Huang T, Reger AS, Hurwitz AM, Palzkill T, Logsdon C, Liang X, Gray JW, Nan X, Hancock J, Wahl GM, Bast RC Jr.

Cell Rep. 2019 Dec 10;29(11):3448-3459.e6. doi: 10.1016/j.celrep.2019.11.045.


DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.

Sutton MN, Huang GY, Liang X, Sharma R, Reger AS, Mao W, Pang L, Rask PJ, Lee K, Gray JP, Hurwitz AM, Palzkill T, Millward SW, Kim C, Lu Z, Bast RC Jr.

Cancers (Basel). 2019 Apr 18;11(4). pii: E557. doi: 10.3390/cancers11040557.


[Effect of distal interphalangeal joint fusion of the index or middle finger on the grip or finger force and load distribution in the hand].

Mühldorfer-Fodor M, Reger A, Pillukat T, Mittlmeier T, van Schoonhoven J, Prommersberger KJ.

Handchir Mikrochir Plast Chir. 2018 Jun;50(3):174-183. doi: 10.1055/a-0645-6867. Epub 2018 Jul 25. German.


Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury.

Buonfiglio LG, Bagegni M, Borcherding JA, Sieren JC, Caraballo JC, Reger A, Zabner J, Li X, Comellas AP.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):869-877.


Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation.

Kim JJ, Lorenz R, Arold ST, Reger AS, Sankaran B, Casteel DE, Herberg FW, Kim C.

Structure. 2016 May 3;24(5):710-720. doi: 10.1016/j.str.2016.03.009. Epub 2016 Apr 7.


Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.

Campbell JC, Kim JJ, Li KY, Huang GY, Reger AS, Matsuda S, Sankaran B, Link TM, Yuasa K, Ladbury JE, Casteel DE, Kim C.

J Biol Chem. 2016 Mar 11;291(11):5623-33. doi: 10.1074/jbc.M115.691303. Epub 2016 Jan 14.


The Effect of Midcarpal Versus Total Wrist Fusion on the Hand's Load Distribution During Gripping.

Mühldorfer-Fodor M, Reger A, Schoonhoven Jv, Mittlmeier T, Prommersberger KJ.

J Hand Surg Am. 2015 Nov;40(11):2183-90. doi: 10.1016/j.jhsa.2015.08.010. Epub 2015 Sep 26.


Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.

Qin L, Reger AS, Guo E, Yang MP, Zwart P, Casteel DE, Kim C.

Biochemistry. 2015 Jul 28;54(29):4419-22. doi: 10.1021/acs.biochem.5b00572. Epub 2015 Jul 15.


Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions.

Reger AS, Yang MP, Koide-Yoshida S, Guo E, Mehta S, Yuasa K, Liu A, Casteel DE, Kim C.

J Biol Chem. 2014 Sep 12;289(37):25393-403. doi: 10.1074/jbc.M114.575894. Epub 2014 Jul 28.


DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells.

Lu Z, Baquero MT, Yang H, Yang M, Reger AS, Kim C, Levine DA, Clarke CH, Liao WS, Bast RC Jr.

Autophagy. 2014 Jun;10(6):1071-92. doi: 10.4161/auto.28577. Erratum in: Autophagy. 2014 Aug;10(8):1482.


Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.

Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C.

Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14.


Wildfire exposure analysis on the national forests in the Pacific Northwest, USA.

Ager AA, Buonopane M, Reger A, Finney MA.

Risk Anal. 2013 Jun;33(6):1000-20. doi: 10.1111/j.1539-6924.2012.01911.x. Epub 2012 Oct 18.


The mechanism of domain alternation in the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase.

Wu R, Reger AS, Lu X, Gulick AM, Dunaway-Mariano D.

Biochemistry. 2009 May 19;48(19):4115-25. doi: 10.1021/bi9002327.


Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis.

Wu R, Cao J, Lu X, Reger AS, Gulick AM, Dunaway-Mariano D.

Biochemistry. 2008 Aug 5;47(31):8026-39. doi: 10.1021/bi800698m. Epub 2008 Jul 12.


Structural characterization of a 140 degrees domain movement in the two-step reaction catalyzed by 4-chlorobenzoate:CoA ligase.

Reger AS, Wu R, Dunaway-Mariano D, Gulick AM.

Biochemistry. 2008 Aug 5;47(31):8016-25. doi: 10.1021/bi800696y. Epub 2008 Jul 12.


Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.

Wu R, Reger AS, Cao J, Gulick AM, Dunaway-Mariano D.

Biochemistry. 2007 Dec 18;46(50):14487-99. Epub 2007 Nov 21.


Role for the RecBCD recombination pathway for pilE gene variation in repair-proficient Neisseria gonorrhoeae.

Hill SA, Woodward T, Reger A, Baker R, Dinse T.

J Bacteriol. 2007 Nov;189(22):7983-90. Epub 2007 Sep 14.


Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase.

Reger AS, Carney JM, Gulick AM.

Biochemistry. 2007 Jun 5;46(22):6536-46. Epub 2007 May 12.


Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli.

Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax WL, Gulick AM.

Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):734-40. Epub 2006 Jun 20.


RelA alone appears essential for (p)ppGpp production when Neisseria gonorrhoeae encounters nutritional stress.

Fisher SD, Reger AD, Baum A, Hill SA.

FEMS Microbiol Lett. 2005 Jul 1;248(1):1-8.

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