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Items: 7


HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL.

Regeling A, Imhann F, Volders HH, Blokzijl T, Bloks VW, Weersma RK, Dijkstra G, Faber KN.

Biochim Biophys Acta. 2016 Apr;1862(4):788-796. doi: 10.1016/j.bbadis.2016.01.020. Epub 2016 Jan 26.


The ATG16L1-T300A allele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients.

Sadaghian Sadabad M, Regeling A, de Goffau MC, Blokzijl T, Weersma RK, Penders J, Faber KN, Harmsen HJ, Dijkstra G.

Gut. 2015 Oct;64(10):1546-52. doi: 10.1136/gutjnl-2014-307289. Epub 2014 Sep 24.


Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease.

Parikh K, Zhou L, Somasundaram R, Fuhler GM, Deuring JJ, Blokzijl T, Regeling A, Kuipers EJ, Weersma RK, Nuij VJ, Alves M, Vogelaar L, Visser L, de Haar C, Krishnadath KK, van der Woude CJ, Dijkstra G, Faber KN, Peppelenbosch MP.

Sci Transl Med. 2014 Apr 23;6(233):233ra53. doi: 10.1126/scitranslmed.3006763.


Role of defective autophagia and the intestinal flora in Crohn disease.

Regeling A, Somasundaram R, de Haar C, van der Woude CJ, Braat H, Peppelenbosch MP.

Self Nonself. 2010 Oct-Dec;1(4):323-327. doi: 10.4161/self.1.4.13990. Review.


Mice defective in p53 nuclear localization signal 1 exhibit exencephaly.

Regeling A, Armata HL, Gallant J, Jones SN, Sluss HK.

Transgenic Res. 2011 Aug;20(4):899-912. doi: 10.1007/s11248-010-9468-4. Epub 2010 Dec 3.


Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1.

de Groot DJ, van der Deen M, Le TK, Regeling A, de Jong S, de Vries EG.

Br J Cancer. 2007 Oct 22;97(8):1077-83. Epub 2007 Oct 16.


Arginine 357 of SecY is needed for SecA-dependent initiation of preprotein translocation.

de Keyzer J, Regeling A, Driessen AJ.

FEBS Lett. 2007 May 1;581(9):1859-64. Epub 2007 Apr 9.

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