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Items: 13

1.

Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor.

Marro ML, Patterson AW, Lee L, Deng L, Reynolds A, Ren X, Axford L, Patnaik A, Hollis-Symynkywicz M, Casson N, Custeau D, Ames L, Loi S, Zhang L, Honda T, Blank J, Harrison TJ, Papillon JPN, Hamann LG, Marcinkeviciene J, Regard JB.

J Pharmacol Exp Ther. 2018 Oct;367(1):147-154. doi: 10.1124/jpet.118.248435. Epub 2018 Aug 3.

PMID:
30076263
2.

Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.

Berger M, Scheel DW, Macias H, Miyatsuka T, Kim H, Hoang P, Ku GM, Honig G, Liou A, Tang Y, Regard JB, Sharifnia P, Yu L, Wang J, Coughlin SR, Conklin BR, Deneris ES, Tecott LH, German MS.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2888-93. doi: 10.1073/pnas.1319378112. Epub 2015 Feb 18.

3.

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.

Regard JB, Malhotra D, Gvozdenovic-Jeremic J, Josey M, Chen M, Weinstein LS, Lu J, Shore EM, Kaplan FS, Yang Y.

Nat Med. 2013 Nov;19(11):1505-12. doi: 10.1038/nm.3314. Epub 2013 Sep 29.

4.

Wnt signaling in bone development and disease: making stronger bone with Wnts.

Regard JB, Zhong Z, Williams BO, Yang Y.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a007997. doi: 10.1101/cshperspect.a007997. Review.

5.

Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia.

Regard JB, Cherman N, Palmer D, Kuznetsov SA, Celi FS, Guettier JM, Chen M, Bhattacharyya N, Wess J, Coughlin SR, Weinstein LS, Collins MT, Robey PG, Yang Y.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20101-6. doi: 10.1073/pnas.1114656108. Epub 2011 Nov 21.

6.

Local protease signaling contributes to neural tube closure in the mouse embryo.

Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, Srinivasan Y, Brown C, Xu SM, Regard JB, Lin CY, Craik CS, Kirchhofer D, Coughlin SR.

Dev Cell. 2010 Jan 19;18(1):25-38. doi: 10.1016/j.devcel.2009.11.014.

7.

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.

Camerer E, Regard JB, Cornelissen I, Srinivasan Y, Duong DN, Palmer D, Pham TH, Wong JS, Pappu R, Coughlin SR.

J Clin Invest. 2009 Jul;119(7):1871-9.

8.

Anatomical profiling of G protein-coupled receptor expression.

Regard JB, Sato IT, Coughlin SR.

Cell. 2008 Oct 31;135(3):561-71. doi: 10.1016/j.cell.2008.08.040.

9.

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

Regard JB, Kataoka H, Cano DA, Camerer E, Yin L, Zheng YW, Scanlan TS, Hebrok M, Coughlin SR.

J Clin Invest. 2007 Dec;117(12):4034-43.

10.

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate.

Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, Xu Y, Camerer E, Zheng YW, Huang Y, Cyster JG, Coughlin SR.

Science. 2007 Apr 13;316(5822):295-8. Epub 2007 Mar 15.

11.

Verge: a novel vascular early response gene.

Regard JB, Scheek S, Borbiev T, Lanahan AA, Schneider A, Demetriades AM, Hiemisch H, Barnes CA, Verin AD, Worley PF.

J Neurosci. 2004 Apr 21;24(16):4092-103.

12.

cDNA cloning of rabbit thrombomodulin and characterization of gene expression in cardiovascular tissue.

Deming CB, Kim AY, Bian CE, Regard JB, Rade JJ.

DNA Seq. 2003 Dec;14(6):399-405.

PMID:
15018348
13.

Stable association of presenilin derivatives and absence of presenilin interactions with APP.

Thinakaran G, Regard JB, Bouton CM, Harris CL, Price DL, Borchelt DR, Sisodia SS.

Neurobiol Dis. 1998 Apr;4(6):438-53.

PMID:
9666482

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