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Projecting total costs and health consequences of increasing mt-sDNA utilization for colorectal cancer screening from the payer and integrated delivery network perspectives.

Hathway JM, Miller-Wilson LA, Jensen IS, Ozbay B, Regan C, Jena AB, Weinstein MC, Parks PD.

J Med Econ. 2020 Feb 17:1. doi: 10.1080/13696998.2020.1730123. [Epub ahead of print]


Electronic cigarettes and obstetric outcomes: a prospective observational study.

McDonnell BP, Dicker P, Regan CL.

BJOG. 2020 Feb 9. doi: 10.1111/1471-0528.16110. [Epub ahead of print]


Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries.

Canfell K, Kim JJ, Brisson M, Keane A, Simms KT, Caruana M, Burger EA, Martin D, Nguyen DTN, Bénard É, Sy S, Regan C, Drolet M, Gingras G, Laprise JF, Torode J, Smith MA, Fidarova E, Trapani D, Bray F, Ilbawi A, Broutet N, Hutubessy R.

Lancet. 2020 Jan 30. pii: S0140-6736(20)30157-4. doi: 10.1016/S0140-6736(20)30157-4. [Epub ahead of print]


Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries.

Brisson M, Kim JJ, Canfell K, Drolet M, Gingras G, Burger EA, Martin D, Simms KT, Bénard É, Boily MC, Sy S, Regan C, Keane A, Caruana M, Nguyen DTN, Smith MA, Laprise JF, Jit M, Alary M, Bray F, Fidarova E, Elsheikh F, Bloem PJN, Broutet N, Hutubessy R.

Lancet. 2020 Jan 30. pii: S0140-6736(20)30068-4. doi: 10.1016/S0140-6736(20)30068-4. [Epub ahead of print]


Characterization of Ubrogepant: A Potent and Selective Antagonist of the Human Calcitonin Gene‒Related Peptide Receptor.

Moore E, Fraley ME, Bell IM, Burgey CS, White RB, Li CC, Regan CP, Danziger A, Stranieri Michener M, Hostetler E, Banerjee P, Salvatore C.

J Pharmacol Exp Ther. 2020 Jan 28. pii: jpet.119.261065. doi: 10.1124/jpet.119.261065. [Epub ahead of print]


Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay.

Morissette P, Polak S, Chain A, Zhai J, Imredy JP, Wildey MJ, Travis J, Fitzgerald K, Fanelli P, Passini E, Rodriguez B, Sannajust F, Regan C.

Toxicol Appl Pharmacol. 2020 Mar 1;390:114883. doi: 10.1016/j.taap.2020.114883. Epub 2020 Jan 23.


Development of a semi-automated method to determine the amplitude of the ECG ST-segment to provide refined assessment of preclinical cardiovascular risk.

Fanelli P, Regan C, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.052. Epub 2019 Oct 17. No abstract available.


Characterization of a conscious, restrained, rabbit CV telemetry model for assessing hemodynamic and ECG risk liabilities in early drug research and development.

Fitzgerald K, Morissette P, Chen L, Bueters T, Chaves A, Regan C, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.053. Epub 2019 Oct 17. No abstract available.


Impact of in vitro ion channel protocols when assessing cardiac pro-arrhythmic risk with in silico models.

Morissette P, Imredy J, Zhai J, Travis J, Fanelli P, Dech S, Regan C, Bueno-Orovio A, Passini E, Rodriguez B, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.103. Epub 2019 Oct 17. No abstract available.


Evaluation of clinically-relevant proarrhythmic ECG biomarkers in conscious beagle dogs using a newly developed multiple lead ECG telemetry implant.

Regan C, Delahanty T, Brockway R, Fanelli P, Regan H, Detwiler T, Gruver S, Miller G, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.124. Epub 2019 Oct 17. No abstract available.


Getting more from blood pressure signals: Use of pulse wave analysis (PWA) to enable greater insight to compound-dependent hemodynamic effects.

Regan C, Regan H, Fanelli P, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.122. Epub 2019 Oct 17. No abstract available.


Measurement of heart rate variability (HRV) and spontaneous baroreflex sensitivity (sBRS) provides valuable information on compound-dependent cardiovascular effects to enhance safety risk assessment.

Regan C, Fanelli P, Regan H, Detwiler T, Morissette P, Gruver S, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.123. Epub 2019 Oct 17. No abstract available.


Development and characterization of a nerve conduction model in anesthetized non-human primates as a tool to assess compound-dependent peripheral nervous system risk.

Detwiler T, Regan C, Regan H, Sitko G, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.121. Epub 2019 Oct 17. No abstract available.


Estimating the Natural History of Cervical Carcinogenesis Using Simulation Models: A CISNET Comparative Analysis.

Burger EA, de Kok IMCM, Groene E, Killen J, Canfell K, Kulasingam S, Kuntz KM, Matthijsse S, Regan C, Simms K, Smith M, Sy S, Alarid-Escudero F, Vaidyanathan V, van Ballegooijen M, Kim JJ.

J Natl Cancer Inst. 2019 Dec 10. pii: djz227. doi: 10.1093/jnci/djz227. [Epub ahead of print]


Impact and Cost-Effectiveness of Human Papillomavirus Vaccination Campaigns.

Portnoy A, Campos NG, Sy S, Burger EA, Cohen J, Regan C, Kim JJ.

Cancer Epidemiol Biomarkers Prev. 2020 Jan;29(1):22-30. doi: 10.1158/1055-9965.EPI-19-0767. Epub 2019 Oct 30.


How Much Greater is Obstetric Intervention in Women with Medical Disorders in Pregnancy When Compared to the General Population?

Keane R, Manning C, Lynch C, Regan C, Byrne B.

Ir Med J. 2019 Oct 15;112(9):1001.


Smoking cessation Through Optimisation of clinical care in Pregnancy: the STOP randomised controlled trial.

McDonnell BP, Dicker P, Keogan S, Clancy L, Regan C.

Trials. 2019 Sep 3;20(1):550. doi: 10.1186/s13063-019-3653-4.


Improving the delivery of primary care for older people.

Pond CD, Regan C.

Med J Aust. 2019 Jul;211(2):60-62.e1. doi: 10.5694/mja2.50236. Epub 2019 Jun 17. No abstract available.


Analgesia, anaesthesia and obstetric outcome in women with inherited bleeding disorders.

Boyd SC, O'Connor AD, Horan MA, Dicker P, Manning C, Lynch C, Regan C, Ryan K, Tan T, Byrne BM.

Eur J Obstet Gynecol Reprod Biol. 2019 Aug;239:60-63. doi: 10.1016/j.ejogrb.2019.05.043. Epub 2019 Jun 4.


Quantitative genetics of gastrointestinal strongyle burden and associated body condition in feral horses.

Gold S, Regan CE, McLoughlin PD, Gilleard JS, Wilson AJ, Poissant J.

Int J Parasitol Parasites Wildl. 2019 Apr 6;9:104-111. doi: 10.1016/j.ijppaw.2019.03.010. eCollection 2019 Aug.


Corrigendum to "Smoking cessation support and obstetric outcomes in an Irish maternity hospital" [Eur. J. Obstet. Gynecol. Reprod. Biol. 232 (2019) 1-4].

McDonnell BP, Keogan S, Clancy L, Regan C.

Eur J Obstet Gynecol Reprod Biol. 2019 May;236:266. doi: 10.1016/j.ejogrb.2019.03.022. Epub 2019 Mar 28. No abstract available.


Drug-coated balloon versus plain old balloon angioplasty in femoropopliteal disease: An updated meta-analysis of randomized controlled trials.

Anantha-Narayanan M, Shah SM, Jelani QU, Garcia S, Ionescu C, Regan C, Mena-Hurtado C.

Catheter Cardiovasc Interv. 2019 Jul 1;94(1):139-148. doi: 10.1002/ccd.28176. Epub 2019 Mar 6.


Review of the Current Basic Science Strategies to Treat Critical Limb Ischemia.

Haghighat L, Ionescu CN, Regan CJ, Altin SE, Attaran RR, Mena-Hurtado CI.

Vasc Endovascular Surg. 2019 May;53(4):316-324. doi: 10.1177/1538574419831489. Epub 2019 Feb 26. Review.


Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology.

Oakland K, Chadwick G, East JE, Guy R, Humphries A, Jairath V, McPherson S, Metzner M, Morris AJ, Murphy MF, Tham T, Uberoi R, Veitch AM, Wheeler J, Regan C, Hoare J.

Gut. 2019 May;68(5):776-789. doi: 10.1136/gutjnl-2018-317807. Epub 2019 Feb 12.


Proteogenomic Analysis of Epibacterium Mobile BBCC367, a Relevant Marine Bacterium Isolated From the South Pacific Ocean.

Matallana-Surget S, Werner J, Wattiez R, Lebaron K, Intertaglia L, Regan C, Morris J, Teeling H, Ferrer M, Golyshin PN, Gerogiorgis D, Reilly SI, Lebaron P.

Front Microbiol. 2018 Dec 21;9:3125. doi: 10.3389/fmicb.2018.03125. eCollection 2018.


Smoking cessation support and obstetric outcomes in an Irish maternity hospital.

McDonnell BP, Keogan S, Clancy L, Regan C.

Eur J Obstet Gynecol Reprod Biol. 2019 Jan;232:1-4. doi: 10.1016/j.ejogrb.2018.11.005. Epub 2018 Nov 12. Erratum in: Eur J Obstet Gynecol Reprod Biol. 2019 May;236:266.


Screening for Cervical Cancer in Primary Care: A Decision Analysis for the U.S. Preventive Services Task Force [Internet].

Kim JJ, Burger EA, Regan C, Sy S.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Aug. No abstract available.

Free Books & Documents

Screening for Cervical Cancer in Primary Care: A Decision Analysis for the US Preventive Services Task Force.

Kim JJ, Burger EA, Regan C, Sy S.

JAMA. 2018 Aug 21;320(7):706-714. doi: 10.1001/jama.2017.19872.


Health impact of delayed implementation of cervical cancer screening programs in India: A modeling analysis.

Campos NG, Tsu V, Jeronimo J, Regan C, Resch S, Clark A, Sy S, Kim JJ.

Int J Cancer. 2019 Feb 15;144(4):687-696. doi: 10.1002/ijc.31823. Epub 2018 Oct 16.


Cost-Effectiveness of Cervical Cancer Screening in Women Living With HIV in South Africa: A Mathematical Modeling Study.

Campos NG, Lince-Deroche N, Chibwesha CJ, Firnhaber C, Smith JS, Michelow P, Meyer-Rath G, Jamieson L, Jordaan S, Sharma M, Regan C, Sy S, Liu G, Tsu V, Jeronimo J, Kim JJ.

J Acquir Immune Defic Syndr. 2018 Oct 1;79(2):195-205. doi: 10.1097/QAI.0000000000001778.


Community-based HPV self-collection versus visual inspection with acetic acid in Uganda: a cost-effectiveness analysis of the ASPIRE trial.

Mezei AK, Pedersen HN, Sy S, Regan C, Mitchell-Foster SM, Byamugisha J, Sekikubo M, Armstrong H, Rawat A, Singer J, Ogilvie GS, Kim JJ, Campos NG.

BMJ Open. 2018 Jun 12;8(6):e020484. doi: 10.1136/bmjopen-2017-020484.


Health and economic benefits of single-dose HPV vaccination in a Gavi-eligible country.

Burger EA, Campos NG, Sy S, Regan C, Kim JJ.

Vaccine. 2018 Aug 6;36(32 Pt A):4823-4829. doi: 10.1016/j.vaccine.2018.04.061. Epub 2018 May 26.


Angiogenic Factor Profiles in Pregnant Women With a History of Early-Onset Severe Preeclampsia Receiving Low-Molecular-Weight Heparin Prophylaxis.

McDonnell BP, Regan C.

Obstet Gynecol. 2018 May;131(5):936. doi: 10.1097/AOG.0000000000002607. No abstract available.


Review of the Latest Percutaneous Devices in Critical Limb Ischemia.

Haghighat L, Altin SE, Attaran RR, Mena-Hurtado C, Regan CJ.

J Clin Med. 2018 Apr 14;7(4). pii: E82. doi: 10.3390/jcm7040082. Review.


Declining home range area predicts reduced late-life survival in two wild ungulate populations.

Froy H, Börger L, Regan CE, Morris A, Morris S, Pilkington JG, Crawley MJ, Clutton-Brock TH, Pemberton JM, Nussey DH.

Ecol Lett. 2018 Jul;21(7):1001-1009. doi: 10.1111/ele.12965. Epub 2018 Apr 15.


Organizing seniors to protect the health safety net: the way forward.

Sharma L, Regan C, Villers KS.

J Aging Soc Policy. 2018 May-Jun;30(3-4):400-417. doi: 10.1080/08959420.2018.1462677. Epub 2018 May 3.


Platelet-Activating Factor (PAF) Receptor Antagonism Modulates Inflammatory Signaling in Experimental Uveitis.

Elison JR, Weinstein JE, Sheets KG, Regan CE Jr, Lentz JJ, Reinoso M, Gordon WC, Bazan NG.

Curr Eye Res. 2018 Jun;43(6):821-827. doi: 10.1080/02713683.2018.1454476. Epub 2018 Apr 11.


Novel Entamoeba Findings in Nonhuman Primates.

Elsheikha HM, Regan CS, Clark CG.

Trends Parasitol. 2018 Apr;34(4):283-294. doi: 10.1016/ Epub 2018 Jan 24. Review.


Retrievable Inferior vena cava filters in pregnancy: Risk versus benefit?

Crosby DA, Ryan K, McEniff N, Dicker P, Regan C, Lynch C, Byrne B.

Eur J Obstet Gynecol Reprod Biol. 2018 Mar;222:25-30. doi: 10.1016/j.ejogrb.2017.12.035. Epub 2017 Dec 21. Review.


Momentum transfer Monte Carlo for the simulation of laser speckle imaging and its application in the skin.

Regan C, Hayakawa C, Choi B.

Biomed Opt Express. 2017 Nov 17;8(12):5708-5723. doi: 10.1364/BOE.8.005708. eCollection 2017 Dec 1.


Reducing emergency department visits utilizing a primary care asthma specialty clinic in a high-risk patient population.

Snyder DA, Thomas OW, Gleeson SP, Stukus DR, Jones LM, Regan C, Shamansky A, Allen ED.

J Asthma. 2018 Jul;55(7):785-794. doi: 10.1080/02770903.2017.1369989. Epub 2017 Oct 17.


Maintaining capacity for in-practice teaching and supervision of students and general practice trainees: a cross-sectional study of early career general practitioners.

Catzikiris N, Tapley A, Morgan S, Holliday EG, Ball J, Henderson K, Elliott T, Spike N, Regan C, Magin P.

Aust Health Rev. 2018 Dec;42(6):643-649. doi: 10.1071/AH16285.


Gle1 Regulates RNA Binding of the DEAD-Box Helicase Ded1 in Its Complex Role in Translation Initiation.

Aryanpur PP, Regan CA, Collins JM, Mittelmeier TM, Renner DM, Vergara AM, Brown NP, Bolger TA.

Mol Cell Biol. 2017 Oct 13;37(21). pii: e00139-17. doi: 10.1128/MCB.00139-17. Print 2017 Nov 1.


The health and economic impact of scaling cervical cancer prevention in 50 low- and lower-middle-income countries.

Campos NG, Sharma M, Clark A, Lee K, Geng F, Regan C, Kim J, Resch S.

Int J Gynaecol Obstet. 2017 Jul;138 Suppl 1:47-56. doi: 10.1002/ijgo.12184.


The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity.

Abbott JA, Guth E, Kim C, Regan C, Siu VM, Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM.

Biochemistry. 2017 Jul 18;56(28):3619-3631. doi: 10.1021/acs.biochem.7b00114. Epub 2017 Jul 7.


Corrigendum to "asynchrony of senescence among phenotypic traits in a wild mammal population" [Exp. Gerontol. 71 (2015) 56-68].

Hayward AD, Moorad J, Regan CE, Berenos C, Pilkington JG, Pemberton JM, Nussey DH.

Exp Gerontol. 2017 Oct 1;96:162-163. doi: 10.1016/j.exger.2017.06.001. Epub 2017 Jun 12. No abstract available.


Enantioselective Synthesis of (-)-Acetylapoaranotin.

Wang H, Regan CJ, Codelli JA, Romanato P, Puchlopek-Dermenci AL, Reisman SE.

Org Lett. 2017 Apr 7;19(7):1698-1701. doi: 10.1021/acs.orglett.7b00418. Epub 2017 Mar 28.


Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry.

Lagrutta A, Regan CP, Zeng H, Imredy JP, Koeplinger K, Morissette P, Liu L, Wollenberg G, Brynczka C, Lebrón J, DeGeorge J, Sannajust F.

Sci Rep. 2017 Mar 22;7:44820. doi: 10.1038/srep44820.


Mechanistic Studies of the Photoinduced Quinone Trimethyl Lock Decaging Process.

Regan CJ, Walton DP, Shafaat OS, Dougherty DA.

J Am Chem Soc. 2017 Apr 5;139(13):4729-4736. doi: 10.1021/jacs.6b12007. Epub 2017 Mar 24.


Climate change and the economics of biomass energy feedstocks in semi-arid agricultural landscapes: A spatially explicit real options analysis.

Regan CM, Connor JD, Raja Segaran R, Meyer WS, Bryan BA, Ostendorf B.

J Environ Manage. 2017 May 1;192:171-183. doi: 10.1016/j.jenvman.2017.01.049. Epub 2017 Feb 2.


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