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Items: 3

1.

In silico and in vitro immunogenicity assessment of B-domain-modified recombinant factor VIII molecules.

Bartholdy C, Reedtz-Runge SL, Wang J, Hjerrild Zeuthen L, Gruhler A, Gudme CN, Lamberth K.

Haemophilia. 2018 Sep;24(5):e354-e362. doi: 10.1111/hae.13555. Epub 2018 Jul 19.

PMID:
30024643
2.

Quantitative analysis of the CD4+ T cell response to therapeutic antibodies in healthy donors using a novel T cell:PBMC assay.

Schultz HS, Reedtz-Runge SL, Bäckström BT, Lamberth K, Pedersen CR, Kvarnhammar AM; ABIRISK consortium.

PLoS One. 2017 May 31;12(5):e0178544. doi: 10.1371/journal.pone.0178544. eCollection 2017.

3.

Post hoc assessment of the immunogenicity of bioengineered factor VIIa demonstrates the use of preclinical tools.

Lamberth K, Reedtz-Runge SL, Simon J, Klementyeva K, Pandey GS, Padkjær SB, Pascal V, León IR, Gudme CN, Buus S, Sauna ZE.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaag1286. doi: 10.1126/scitranslmed.aag1286.

PMID:
28077675

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