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Items: 1 to 50 of 971

1.

Oxidized analogs of Di(1H-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity.

Sanchez M, Xia Z, Rico-Bautista E, Cao X, Cuddy M, Castro DJ, Correa RG, Chen L, Yu J, Bobkov A, Ruvolo V, Andreeff M, Oshima RG, Matsuzawa SI, Reed JC, Zhang XK, Hansel D, Wolf DA, Dawson MI.

Oncotarget. 2018 May 18;9(38):25057-25074. doi: 10.18632/oncotarget.25285. eCollection 2018 May 18.

2.

Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging.

Barajas BC, Tanaka M, Robinson BA, Phuong DJ, Chutiraka K, Reed JC, Lingappa JR.

PLoS Pathog. 2018 Apr 17;14(4):e1006977. doi: 10.1371/journal.ppat.1006977. eCollection 2018 Apr.

3.

Tissue-Specific Immunoregulation: A Call for Better Understanding of the "Immunostat" in the Context of Cancer.

Pao W, Ooi CH, Birzele F, Ruefli-Brasse A, Cannarile MA, Reis B, Scharf SH, Schubert DA, Hatje K, Pelletier N, Spleiss O, Reed JC.

Cancer Discov. 2018 Apr;8(4):395-402. doi: 10.1158/2159-8290.CD-17-1320. Epub 2018 Mar 15.

PMID:
29545369
4.

Formation of RNA Granule-Derived Capsid Assembly Intermediates Appears To Be Conserved between Human Immunodeficiency Virus Type 1 and the Nonprimate Lentivirus Feline Immunodeficiency Virus.

Reed JC, Westergreen N, Barajas BC, Ressler DTB, Phuong DJ, Swain JV, Lingappa VR, Lingappa JR.

J Virol. 2018 Apr 13;92(9). pii: e01761-17. doi: 10.1128/JVI.01761-17. Print 2018 May 1.

PMID:
29467316
5.

Proteins of TNF-α and IL6 Pathways Are Elevated in Serum of Type-1 Diabetes Patients with Microalbuminuria.

Purohit S, Sharma A, Zhi W, Bai S, Hopkins D, Steed L, Bode B, Anderson SW, Reed JC, Steed RD, She JX.

Front Immunol. 2018 Jan 31;9:154. doi: 10.3389/fimmu.2018.00154. eCollection 2018.

6.

Health systems flattening - the failed promises of decentralisation in Mozambique.

Reed JC.

Glob Public Health. 2018 Feb 7:1-16. doi: 10.1080/17441692.2018.1436719. [Epub ahead of print]

PMID:
29411676
7.

Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.

Liu PF, Tsai KL, Hsu CJ, Tsai WL, Cheng JS, Chang HW, Shiau CW, Goan YG, Tseng HH, Wu CH, Reed JC, Yang LW, Shu CW.

Theranostics. 2018 Jan 1;8(3):830-845. doi: 10.7150/thno.22012. eCollection 2018.

8.

Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy.

Pan R, Ruvolo V, Mu H, Leverson JD, Nichols G, Reed JC, Konopleva M, Andreeff M.

Cancer Cell. 2017 Dec 11;32(6):748-760.e6. doi: 10.1016/j.ccell.2017.11.003.

PMID:
29232553
9.

Bcl-2 on the brink of breakthroughs in cancer treatment.

Reed JC.

Cell Death Differ. 2018 Jan;25(1):3-6. doi: 10.1038/cdd.2017.188. No abstract available.

PMID:
29227986
10.

Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.

Sewing S, Roth AB, Winter M, Dieckmann A, Bertinetti-Lapatki C, Tessier Y, McGinnis C, Huber S, Koller E, Ploix C, Reed JC, Singer T, Rothfuss A.

PLoS One. 2017 Nov 6;12(11):e0187574. doi: 10.1371/journal.pone.0187574. eCollection 2017.

11.

Microbiota control immune regulation in humanized mice.

Gülden E, Vudattu NK, Deng S, Preston-Hurlburt P, Mamula M, Reed JC, Mohandas S, Herold BC, Torres R, Vieira SM, Lim B, Herazo-Maya JD, Kriegel M, Goodman AL, Cotsapas C, Herold KC.

JCI Insight. 2017 Nov 2;2(21). pii: 91709. doi: 10.1172/jci.insight.91709. [Epub ahead of print]

12.

Therapeutics targeting Bcl-2 in hematological malignancies.

Ruefli-Brasse A, Reed JC.

Biochem J. 2017 Oct 23;474(21):3643-3657. doi: 10.1042/BCJ20170080. Review.

PMID:
29061914
13.

Peter C. Nowell (1928-2016).

Reed JC, Druker BJ.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4569-4570. doi: 10.1073/pnas.1705526114. Epub 2017 Apr 17. No abstract available.

14.

A Social Work Response to the Affordable Care Act: Prevention and Early Intervention.

Corrigan MJ, Krase K, Reed JC.

J Psychoactive Drugs. 2017 Apr-Jun;49(2):169-173. doi: 10.1080/02791072.2017.1295333. Epub 2017 Mar 15.

PMID:
28296625
15.

Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity.

Joo E, Fukushima T, Harada N, Reed JC, Matsuzawa SI, Inagaki N.

Sci Rep. 2016 Oct 31;6:35983. doi: 10.1038/srep35983.

16.

Finally, An Apoptosis-Targeting Therapeutic for Cancer.

Croce CM, Reed JC.

Cancer Res. 2016 Oct 15;76(20):5914-5920. Epub 2016 Sep 30. Review.

17.

Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis.

Welsh K, Milutinovic S, Ardecky RJ, Gonzalez-Lopez M, Ganji SR, Teriete P, Finlay D, Riedl S, Matsuzawa S, Pinilla C, Houghten R, Vuori K, Reed JC, Cosford ND.

PLoS One. 2016 Sep 12;11(9):e0161952. doi: 10.1371/journal.pone.0161952. eCollection 2016.

18.

IMAGES IN CLINICAL MEDICINE. Diaphragmatic Hernia Causing Lung Collapse.

Yasin M, Reed JC.

N Engl J Med. 2016 May 12;374(19):1874. doi: 10.1056/NEJMicm1415660. No abstract available.

19.

Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins.

Godoi PH, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa S, Reed JC.

J Biol Chem. 2016 Jul 1;291(27):14072-84. doi: 10.1074/jbc.M116.715235. Epub 2016 Apr 19.

20.

Defective Angiogenesis and Intraretinal Bleeding in Mouse Models With Disrupted Inner Retinal Lamination.

Simmons AB, Merrill MM, Reed JC, Deans MR, Edwards MM, Fuerst PG.

Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1563-77. doi: 10.1167/iovs.15-18395.

21.

Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).

Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA.

PLoS One. 2016 Mar 31;11(3):e0152692. doi: 10.1371/journal.pone.0152692. eCollection 2016.

22.

Optomechanical Enhancement of Doubly Resonant 2D Optical Nonlinearity.

Yi F, Ren M, Reed JC, Zhu H, Hou J, Naylor CH, Johnson AT, Agarwal R, Cubukcu E.

Nano Lett. 2016 Mar 9;16(3):1631-6. doi: 10.1021/acs.nanolett.5b04448. Epub 2016 Feb 15.

PMID:
26854706
23.

Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation.

Lee H, Rotolo JA, Mesicek J, Penate-Medina T, Rimner A, Liao WC, Yin X, Ragupathi G, Ehleiter D, Gulbins E, Zhai D, Reed JC, Haimovitz-Friedman A, Fuks Z, Kolesnick R.

PLoS One. 2015 Dec 30;10(12):e0146210. doi: 10.1371/journal.pone.0146210. eCollection 2015. No abstract available.

24.

Mutations of Conserved Residues in the Major Homology Region Arrest Assembling HIV-1 Gag as a Membrane-Targeted Intermediate Containing Genomic RNA and Cellular Proteins.

Tanaka M, Robinson BA, Chutiraka K, Geary CD, Reed JC, Lingappa JR.

J Virol. 2015 Dec 9;90(4):1944-63. doi: 10.1128/JVI.02698-15. Print 2016 Feb 15.

25.

Contributions to Neuropsychology of Reitan and Associates: Neuropsychology Laboratory, Indiana University Medical Center, 1960s.

Reed JC, Reed HB Jr.

Arch Clin Neuropsychol. 2015 Dec;30(8):751-3. doi: 10.1093/arclin/acv073. No abstract available.

PMID:
26590076
26.

Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.

Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC.

Mol Cancer Ther. 2016 Jan;15(1):114-24. doi: 10.1158/1535-7163.MCT-15-0400. Epub 2015 Oct 29.

27.

BAX inhibitor-1 is a Ca(2+) channel critically important for immune cell function and survival.

Lisak D, Schacht T, Gawlitza A, Albrecht P, Aktas O, Koop B, Gliem M, Hofstetter HH, Zanger K, Bultynck G, Parys JB, De Smedt H, Kindler T, Adams-Quack P, Hahn M, Waisman A, Reed JC, Hövelmeyer N, Methner A.

Cell Death Differ. 2016 Feb;23(2):358-68. doi: 10.1038/cdd.2015.115. Epub 2015 Oct 16.

28.

ATG4B (Autophagin-1) phosphorylation modulates autophagy.

Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC.

J Biol Chem. 2015 Oct 30;290(44):26549-61. doi: 10.1074/jbc.M115.658088. Epub 2015 Sep 16.

29.

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2.

Wagner RN, Reed JC, Chanda SK.

Retrovirology. 2015 Aug 22;12:74. doi: 10.1186/s12977-015-0200-6.

30.

Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.

Rong J, Pass I, Diaz PW, Ngo TA, Sauer M, Magnuson G, Zeng FY, Hassig CA, Jackson MR, Cosford ND, Matsuzawa S, Reed JC.

J Biomol Screen. 2015 Dec;20(10):1232-45. doi: 10.1177/1087057115600414. Epub 2015 Aug 11.

PMID:
26265713
31.

Large-Scale Discovery and Validation Studies Demonstrate Significant Reductions in Circulating Levels of IL8, IL-1Ra, MCP-1, and MIP-1β in Patients With Type 1 Diabetes.

Purohit S, Sharma A, Hopkins D, Steed L, Bode B, Anderson SW, Reed JC, Steed RD, Yang T, She JX.

J Clin Endocrinol Metab. 2015 Sep;100(9):E1179-87. doi: 10.1210/JC.2015-1388. Epub 2015 Jul 9.

32.

Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.

D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, Reed JC.

PLoS One. 2015 Jun 18;10(6):e0130635. doi: 10.1371/journal.pone.0130635. eCollection 2015.

33.

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team.

Cell. 2015 Jun 4;161(6):1252-65. doi: 10.1016/j.cell.2015.05.023. Review.

34.

Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.

Pan R, Ruvolo VR, Wei J, Konopleva M, Reed JC, Pellecchia M, Andreeff M, Ruvolo PP.

Blood. 2015 Jul 16;126(3):363-72. doi: 10.1182/blood-2014-10-604975. Epub 2015 Jun 4.

35.

Situs ambiguous, levocardia, right sided stomach, obstructing duodenal web, and intestinal nonrotation: a case report.

Mujo T, Finnegan T, Joshi J, Wilcoxen KA, Reed JC.

J Radiol Case Rep. 2015 Feb 28;9(2):16-23. doi: 10.3941/jrcr.v9i2.2358. eCollection 2015 Feb.

36.

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.

Qiao S, Dennis M, Song X, Vadysirisack DD, Salunke D, Nash Z, Yang Z, Liesa M, Yoshioka J, Matsuzawa S, Shirihai OS, Lee RT, Reed JC, Ellisen LW.

Nat Commun. 2015 Apr 28;6:7014. doi: 10.1038/ncomms8014.

37.

Therapeutic targeting of Bcl-2 family for treatment of B-cell malignancies.

Huang J, Fairbrother W, Reed JC.

Expert Rev Hematol. 2015 Jun;8(3):283-97. doi: 10.1586/17474086.2015.1026321. Epub 2015 Apr 25. Review.

PMID:
25912824
38.

PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines.

Yanagi T, Shi R, Aza-Blanc P, Reed JC, Matsuzawa S.

PLoS One. 2015 Mar 19;10(3):e0119404. doi: 10.1371/journal.pone.0119404. eCollection 2015.

39.

Wavelength tunable microdisk cavity light source with a chemically enhanced MoS2 emitter.

Reed JC, Zhu AY, Zhu H, Yi F, Cubukcu E.

Nano Lett. 2015 Mar 11;15(3):1967-71. doi: 10.1021/nl5048303. Epub 2015 Mar 2.

PMID:
25723816
40.

Thinking bedside at the bench: the NOD mouse model of T1DM.

Reed JC, Herold KC.

Nat Rev Endocrinol. 2015 May;11(5):308-14. doi: 10.1038/nrendo.2014.236. Epub 2015 Jan 27. Review.

41.

NLRs: Sentinels of innate immunity or cancer culprits?

Correa RG, Ware CF, Reed JC.

Oncoscience. 2014 May 26;1(5):308-9. eCollection 2014. No abstract available.

42.

PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma.

Yanagi T, Reed JC, Matsuzawa S.

Oncoscience. 2014 Oct 5;1(10):624-33. eCollection 2014.

43.

Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines.

Zou H, Limpert AS, Zou J, Dembo A, Lee PS, Grant D, Ardecky R, Pinkerton AB, Magnuson GK, Goldman ME, Rong J, Teriete P, Sheffler DJ, Reed JC, Cosford ND.

ACS Chem Neurosci. 2015 Mar 18;6(3):464-75. doi: 10.1021/cn500297v. Epub 2015 Jan 17.

44.

Transparent and flexible low noise graphene electrodes for simultaneous electrophysiology and neuroimaging.

Kuzum D, Takano H, Shim E, Reed JC, Juul H, Richardson AG, de Vries J, Bink H, Dichter MA, Lucas TH, Coulter DA, Cubukcu E, Litt B.

Nat Commun. 2014 Oct 20;5:5259. doi: 10.1038/ncomms6259.

45.

PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.

Yanagi T, Krajewska M, Matsuzawa S, Reed JC.

Cancer Res. 2014 Oct 15;74(20):5795-807. doi: 10.1158/0008-5472.CAN-14-0872. Epub 2014 Sep 9.

46.

Optoelectromechanical multimodal biosensor with graphene active region.

Zhu AY, Yi F, Reed JC, Zhu H, Cubukcu E.

Nano Lett. 2014 Oct 8;14(10):5641-9. doi: 10.1021/nl502279c. Epub 2014 Sep 5.

PMID:
25184967
47.

How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle.

Lingappa JR, Reed JC, Tanaka M, Chutiraka K, Robinson BA.

Virus Res. 2014 Nov 26;193:89-107. doi: 10.1016/j.virusres.2014.07.001. Epub 2014 Jul 24. Review.

48.

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.

Hassig CA, Zeng FY, Kung P, Kiankarimi M, Kim S, Diaz PW, Zhai D, Welsh K, Morshedian S, Su Y, O'Keefe B, Newman DJ, Rusman Y, Kaur H, Salomon CE, Brown SG, Baire B, Michel AR, Hoye TR, Francis S, Georg GI, Walters MA, Divlianska DB, Roth GP, Wright AE, Reed JC.

J Biomol Screen. 2014 Sep;19(8):1201-11. doi: 10.1177/1087057114536227. Epub 2014 May 27.

49.

Selective UBC 13 Inhibitors.

Ardecky R, Madiraj C, Matsuzawa S, Zou J, Ganji S, Pass I, Ngo TA, Pinkerton AB, Sergienko E, Su Y, Stonich D, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Matsuzawa Y, Wimer C, Diaz PW, Reed JC.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Apr 16 [updated 2014 May 13].

50.

The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.

Correa RG, Krajewska M, Ware CF, Gerlic M, Reed JC.

Oncotarget. 2014 Mar 30;5(6):1666-82.

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