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Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment.

Reed DR, Elsarrag RZ, Morris AL, Keng MK.

Cancer Manag Res. 2019 Aug 30;11:8073-8080. doi: 10.2147/CMAR.S162784. eCollection 2019.


Chemosensory Changes from Cancer Treatment and Their Effects on Patients' Food Behavior: A Scoping Review.

Nolden AA, Hwang LD, Boltong A, Reed DR.

Nutrients. 2019 Sep 24;11(10). pii: E2285. doi: 10.3390/nu11102285. Review.


Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.

Welch D, Kahen E, Fridley B, Brohl AS, Cubitt CL, Reed DR.

PLoS One. 2019 Sep 24;14(9):e0222228. doi: 10.1371/journal.pone.0222228. eCollection 2019.


Multifocal primary neuroblastoma tumor heterogeneity in siblings with co-occurring PHOX2B and NF1 genetic aberrations.

Rybinski B, Wolinsky T, Brohl A, Moerdler S, Reed DR, Ewart M, Weiser D.

Genes Chromosomes Cancer. 2019 Sep 12. doi: 10.1002/gcc.22809. [Epub ahead of print]


A prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate.

Reed DR, Pierce EJ, Sen JM, Keng MK.

Cancer Manag Res. 2019 Aug 30;11:8065-8072. doi: 10.2147/CMAR.S190084. eCollection 2019.


Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group.

Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabello L, Malkin D, Sorensen PH, Meltzer PS, Janeway KA, Gorlick R, Crompton BD.

Cancer. 2019 Oct 15;125(20):3514-3525. doi: 10.1002/cncr.32351. Epub 2019 Jul 29. Review.


Sensory nutrition: The role of taste in the reviews of commercial food products.

Reed DR, Mainland JD, Arayata CJ.

Physiol Behav. 2019 Oct 1;209:112579. doi: 10.1016/j.physbeh.2019.112579. Epub 2019 Jun 12.


Overall survival and histology-specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma.

Patel S, von Mehren M, Reed DR, Kaiser P, Charlson J, Ryan CW, Rushing D, Livingston M, Singh A, Seth R, Forscher C, D'Amato G, Chawla SP, McCarthy S, Wang G, Parekh T, Knoblauch R, Hensley ML, Maki RG, Demetri GD.

Cancer. 2019 Aug 1;125(15):2610-2620. doi: 10.1002/cncr.32117. Epub 2019 Jun 7.


NTRK-1 fusion in endocervical fibroblastic malignant peripheral nerve sheath tumor marking eligibility for larotrectinib therapy: A case report.

Wells AE, Mallen AM, Bui MM, Reed DR, Apte SM.

Gynecol Oncol Rep. 2019 Apr 23;28:141-144. doi: 10.1016/j.gore.2019.04.006. eCollection 2019 May.


Sarcoma as a Model for Adolescent and Young Adult Care.

Reed DR, Naghavi A, Binitie O.

J Oncol Pract. 2019 May;15(5):239-247. doi: 10.1200/JOP.18.00684.


New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances.

Hwang LD, Lin C, Gharahkhani P, Cuellar-Partida G, Ong JS, An J, Gordon SD, Zhu G, MacGregor S, Lawlor DA, Breslin PAS, Wright MJ, Martin NG, Reed DR.

Am J Clin Nutr. 2019 Jun 1;109(6):1724-1737. doi: 10.1093/ajcn/nqz043.


Treatment of Refractory ALK Rearranged Anaplastic Large Cell Lymphoma With Alectinib.

Reed DR, Hall RD, Gentzler RD, Volodin L, Douvas MG, Portell CA.

Clin Lymphoma Myeloma Leuk. 2019 Jun;19(6):e247-e250. doi: 10.1016/j.clml.2019.03.001. Epub 2019 Mar 11. No abstract available.


Provider perceptions' of a patient navigator for adolescents and young adults with cancer.

LaRosa KN, Stern M, Lynn C, Hudson J, Reed DR, Donovan KA, Quinn GP.

Support Care Cancer. 2019 Nov;27(11):4091-4098. doi: 10.1007/s00520-019-04687-3. Epub 2019 Feb 18.


Associations between brain structure and perceived intensity of sweet and bitter tastes.

Hwang LD, Strike LT, Couvy-Duchesne B, de Zubicaray GI, McMahon K, Breslin PAS, Reed DR, Martin NG, Wright MJ.

Behav Brain Res. 2019 May 2;363:103-108. doi: 10.1016/j.bbr.2019.01.046. Epub 2019 Jan 28.


Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA.

Douglas JE, Lin C, Mansfield CJ, Arayata CJ, Cowart BJ, Spielman AI, Adappa ND, Palmer JN, Cohen NA, Reed DR.

Chem Senses. 2019 Jan 1;44(1):33-40. doi: 10.1093/chemse/bjy066.


Personalized expression of bitter 'taste' receptors in human skin.

Shaw L, Mansfield C, Colquitt L, Lin C, Ferreira J, Emmetsberger J, Reed DR.

PLoS One. 2018 Oct 17;13(10):e0205322. doi: 10.1371/journal.pone.0205322. eCollection 2018.


Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste.

Hwang LD, Gharahkhani P, Breslin PAS, Gordon SD, Zhu G, Martin NG, Reed DR, Wright MJ.

BMC Genomics. 2018 Sep 17;19(1):678. doi: 10.1186/s12864-018-5058-2.


Taste Exam: A Brief and Validated Test.

Douglas JE, Mansfield CJ, Arayata CJ, Cowart BJ, Colquitt LR, Maina IW, Blasetti MT, Cohen NA, Reed DR.

J Vis Exp. 2018 Aug 17;(138). doi: 10.3791/56705.


Cognition in Adolescent and Young Adults Diagnosed With Cancer: An Understudied Problem.

Jim HSL, Jennewein SL, Quinn GP, Reed DR, Small BJ.

J Clin Oncol. 2018 Sep 20;36(27):2752-2754. doi: 10.1200/JCO.2018.78.0627. Epub 2018 Jul 24. No abstract available.


A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metformin with induction chemotherapy of vincristine, dexamethasone, PEG-asparaginase, and doxorubicin.

Trucco M, Barredo JC, Goldberg J, Leclerc GM, Hale GA, Gill J, Setty B, Smith T, Lush R, Lee JK, Reed DR.

Pediatr Blood Cancer. 2018 Sep;65(9):e27224. doi: 10.1002/pbc.27224. Epub 2018 Jun 1.


Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors.

Kahen EJ, Brohl A, Yu D, Welch D, Cubitt CL, Lee JK, Chen Y, Yoder SJ, Teer JK, Zhang YO, Wallace MR, Reed DR.

Oncotarget. 2018 Apr 27;9(32):22571-22585. doi: 10.18632/oncotarget.25181. eCollection 2018 Apr 27.


Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling.

Freund JR, Mansfield CJ, Doghramji LJ, Adappa ND, Palmer JN, Kennedy DW, Reed DR, Jiang P, Lee RJ.

J Biol Chem. 2018 Jun 22;293(25):9824-9840. doi: 10.1074/jbc.RA117.001005. Epub 2018 May 10.


Burly1 is a mouse QTL for lean body mass that maps to a 0.8-Mb region of chromosome 2.

Lin C, Fesi BD, Marquis M, Bosak NP, Lysenko A, Koshnevisan MA, Duke FF, Theodorides ML, Nelson TM, McDaniel AH, Avigdor M, Arayata CJ, Shaw L, Bachmanov AA, Reed DR.

Mamm Genome. 2018 Jun;29(5-6):325-343. doi: 10.1007/s00335-018-9746-7. Epub 2018 May 8.


The Role of Quinine-Responsive Taste Receptor Family 2 in Airway Immune Defense and Chronic Rhinosinusitis.

Workman AD, Maina IW, Brooks SG, Kohanski MA, Cowart BJ, Mansfield C, Kennedy DW, Palmer JN, Adappa ND, Reed DR, Lee RJ, Cohen NA.

Front Immunol. 2018 Mar 28;9:624. doi: 10.3389/fimmu.2018.00624. eCollection 2018.


Higher than reported adolescent and young adult clinical trial enrollment during the "Golden Age" of melanoma clinical trials.

Sreeraman Kumar R, Thapa R, Kim Y, Khushalani NI, Sondak VK, Reed DR.

Cancer Med. 2018 Apr;7(4):991-996. doi: 10.1002/cam4.1307. Epub 2018 Feb 25.


Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains.

Lin C, Fesi BD, Marquis M, Bosak NP, Lysenko A, Koshnevisan MA, Duke FF, Theodorides ML, Nelson TM, McDaniel AH, Avigdor M, Arayata CJ, Shaw L, Bachmanov AA, Reed DR.

PLoS One. 2017 Dec 1;12(12):e0188972. doi: 10.1371/journal.pone.0188972. eCollection 2017.


The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation.

Brohl AS, Kahen E, Yoder SJ, Teer JK, Reed DR.

Sci Rep. 2017 Nov 8;7(1):14992. doi: 10.1038/s41598-017-15183-1. Review.


Bitter and sweet taste tests are reflective of disease status in chronic rhinosinusitis.

Workman AD, Brooks SG, Kohanski MA, Blasetti MT, Cowart BJ, Mansfield C, Kennedy DW, Palmer JN, Adappa ND, Reed DR, Cohen NA.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):1078-1080. doi: 10.1016/j.jaip.2017.09.014. Epub 2017 Oct 18. No abstract available.


Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.

Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S.

Lancet Oncol. 2017 Nov;18(11):1493-1501. doi: 10.1016/S1470-2045(17)30624-1. Epub 2017 Oct 4. Erratum in: Lancet Oncol. 2017 Dec;18(12 ):e711. Erratum in: Lancet Oncol. 2018 Jan;19(1):e8.


Consensus and controversies regarding the treatment of rhabdomyosarcoma.

Borinstein SC, Steppan D, Hayashi M, Loeb DM, Isakoff MS, Binitie O, Brohl AS, Bridge JA, Stavas M, Shinohara ET, Meyer WH, Reed DR, Wagner LM.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26809. Epub 2017 Sep 14. Review.


Sink or Collaborate: How the Immersive Model Has Helped Address Typical Adolescent and Young Adult Barriers at a Single Institution and Kept the Adolescent and Young Adult Program Afloat.

Reed DR, Oshrine B, Pratt C, Fridgen O, Elstner C, Wilson L, Soliman H, Lee MC, McLeod HL, Shah B, Donovan KA, Pabbathi S, Turney M, Binitie O, Healy C, Nieder M, Shaw PH, Galligan A, Letson GD, Stern M, Quinn GP, Davies S.

J Adolesc Young Adult Oncol. 2017 Dec;6(4):503-511. doi: 10.1089/jayao.2017.0051. Epub 2017 Aug 4. No abstract available.


Adolescent and Young Adult Patients with Cancer: Perceptions of Care.

LaRosa KN, Stern M, Bleck J, Lynn C, Hudson J, Reed DR, Quinn GP, Donovan KA.

J Adolesc Young Adult Oncol. 2017 Dec;6(4):512-518. doi: 10.1089/jayao.2017.0012. Epub 2017 May 24.


Myoepithelial carcinoma with RB1 mutation: remarkable chemosensitivity to carcinoma of unknown origin therapy.

Hoggard TM, Henderson-Jackson E, Bui MM, Caracciolo J, Teer JK, Yoder S, Binitie O, Gonzalez RJ, Brohl AS, Reed DR.

BMC Cancer. 2017 Apr 8;17(1):250. doi: 10.1186/s12885-017-3249-x.


Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor.

Hariri BM, McMahon DB, Chen B, Freund JR, Mansfield CJ, Doghramji LJ, Adappa ND, Palmer JN, Kennedy DW, Reed DR, Jiang P, Lee RJ.

J Biol Chem. 2017 May 19;292(20):8484-8497. doi: 10.1074/jbc.M116.771949. Epub 2017 Apr 3.


Treatment pathway of bone sarcoma in children, adolescents, and young adults.

Reed DR, Hayashi M, Wagner L, Binitie O, Steppan DA, Brohl AS, Shinohara ET, Bridge JA, Loeb DM, Borinstein SC, Isakoff MS.

Cancer. 2017 Jun 15;123(12):2206-2218. doi: 10.1002/cncr.30589. Epub 2017 Mar 21. Review.


Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing.

Guo Y, Hwang LD, Li J, Eades J, Yu CW, Mansfield C, Burdick-Will A, Chang X, Chen Y, Duke FF, Zhang J, Fakharzadeh S, Fennessey P, Keating BJ, Jiang H, Hakonarson H, Reed DR, Preti G.

BMC Med Genet. 2017 Feb 15;18(1):11. doi: 10.1186/s12881-017-0369-8.


NCCN Guidelines Insights: Bone Cancer, Version 2.2017.

Biermann JS, Chow W, Reed DR, Lucas D, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Budd GT, Curry WT, Didwania A, Fabbri N, Hornicek FJ, Kuechle JB, Lindskog D, Mayerson J, McGarry SV, Million L, Morris CD, Movva S, O'Donnell RJ, Randall RL, Rose P, Santana VM, Satcher RL, Schwartz H, Siegel HJ, Thornton K, Villalobos V, Bergman MA, Scavone JL.

J Natl Compr Canc Netw. 2017 Feb;15(2):155-167.


Caffeine Bitterness is Related to Daily Caffeine Intake and Bitter Receptor mRNA Abundance in Human Taste Tissue.

Lipchock SV, Spielman AI, Mennella JA, Mansfield CJ, Hwang LD, Douglas JE, Reed DR.

Perception. 2017 Mar-Apr;46(3-4):245-256. doi: 10.1177/0301006616686098. Epub 2017 Jan 24.


Re-calculating! Navigating through the osteosarcoma treatment roadblock.

McGuire J, Utset-Ward TJ, Reed DR, Lynch CC.

Pharmacol Res. 2017 Mar;117:54-64. doi: 10.1016/j.phrs.2016.12.004. Epub 2016 Dec 7. Review.


Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis.

Chang EH, Willis AL, McCrary HC, Noutsios GT, Le CH, Chiu AG, Mansfield CJ, Reed DR, Brooks SG, Adappa ND, Palmer JN, Cohen NG, Stern DA, Guerra S, Martinez FD.

J Allergy Clin Immunol. 2017 Jun;139(6):1990-1992.e2. doi: 10.1016/j.jaci.2016.10.027. Epub 2016 Dec 3. No abstract available.


Disparities in Adolescents and Young Adults With Cancer

Isenalumhe LL, Fridgen O, Beaupin LK, Quinn GP, Reed DR.

Cancer Control. 2016 Oct;23(4):424-433.


PICASSO III: A Phase III, Placebo-Controlled Study of Doxorubicin With or Without Palifosfamide in Patients With Metastatic Soft Tissue Sarcoma.

Ryan CW, Merimsky O, Agulnik M, Blay JY, Schuetze SM, Van Tine BA, Jones RL, Elias AD, Choy E, Alcindor T, Keedy VL, Reed DR, Taub RN, Italiano A, Garcia Del Muro X, Judson IR, Buck JY, Lebel F, Lewis JJ, Maki RG, Schöffski P.

J Clin Oncol. 2016 Nov 10;34(32):3898-3905. doi: 10.1200/JCO.2016.67.6684. Epub 2016 Sep 30.


Is the Association Between Sweet and Bitter Perception due to Genetic Variation?

Hwang LD, Breslin PA, Reed DR, Zhu G, Martin NG, Wright MJ.

Chem Senses. 2016 Aug 9. pii: bjw083. [Epub ahead of print]


Sweet Taste Perception is Associated with Body Mass Index at the Phenotypic and Genotypic Level.

Hwang LD, Cuellar-Partida G, Ong JS, Breslin PA, Reed DR, MacGregor S, Gharahkhani P, Martin NG, Rentería ME.

Twin Res Hum Genet. 2016 Oct;19(5):465-71. doi: 10.1017/thg.2016.60. Epub 2016 Aug 5.


Genetics of Amino Acid Taste and Appetite.

Bachmanov AA, Bosak NP, Glendinning JI, Inoue M, Li X, Manita S, McCaughey SA, Murata Y, Reed DR, Tordoff MG, Beauchamp GK.

Adv Nutr. 2016 Jul 15;7(4):806S-22S. doi: 10.3945/an.115.011270. Print 2016 Jul. Review.


Identification of clinically achievable combination therapies in childhood rhabdomyosarcoma.

Kahen E, Yu D, Harrison DJ, Clark J, Hingorani P, Cubitt CL, Reed DR.

Cancer Chemother Pharmacol. 2016 Aug;78(2):313-23. doi: 10.1007/s00280-016-3077-8. Epub 2016 Jun 20.


Potential confounders of bisphenol-a analysis in dental materials.

Hope E, Reed DR, Moilanen LH.

Dent Mater. 2016 Aug;32(8):961-7. doi: 10.1016/ Epub 2016 May 30.


Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.

Kothari N, Teer JK, Abbott AM, Srikumar T, Zhang Y, Yoder SJ, Brohl AS, Kim RD, Reed DR, Shibata D.

Cancer. 2016 Sep 15;122(18):2828-35. doi: 10.1002/cncr.30082. Epub 2016 May 31.


The development of sweet taste: From biology to hedonics.

Mennella JA, Bobowski NK, Reed DR.

Rev Endocr Metab Disord. 2016 Jun;17(2):171-8. doi: 10.1007/s11154-016-9360-5. Review.

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