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Items: 1 to 50 of 61

1.

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.

Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ.

Nat Chem Biol. 2020 Jan;16(1):50-59. doi: 10.1038/s41589-019-0424-1. Epub 2019 Dec 9.

PMID:
31819276
2.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, Wang Q, Lindeman A, Reece-Hoyes JS, Russ C, Bonenfant D, Jiang X, Wang Y, Cong F.

Elife. 2019 Nov 19;8. pii: e50223. doi: 10.7554/eLife.50223.

3.

IRF2 is a master regulator of human keratinocyte stem cell fate.

Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, Gubser Keller C, Nigsch F, Salathe A, Terranova R, Reece-Hoyes J, Alford J, Russ C, Knehr J, Hoepfner D, Aebi A, Ruffner H, Beck TC, Jagannathan S, Olson CM, Sheppard HE, Elsarrag SZ, Bouwmeester T, Frederiksen M, Lohmann F, Lin CY, Kirkland S.

Nat Commun. 2019 Oct 14;10(1):4676. doi: 10.1038/s41467-019-12559-x.

4.

USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.

Ji L, Lu B, Zamponi R, Charlat O, Aversa R, Yang Z, Sigoillot F, Zhu X, Hu T, Reece-Hoyes JS, Russ C, Michaud G, Tchorz JS, Jiang X, Cong F.

Nat Commun. 2019 Sep 13;10(1):4184. doi: 10.1038/s41467-019-12143-3.

5.

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.

Planas-Paz L, Sun T, Pikiolek M, Cochran NR, Bergling S, Orsini V, Yang Z, Sigoillot F, Jetzer J, Syed M, Neri M, Schuierer S, Morelli L, Hoppe PS, Schwarzer W, Cobos CM, Alford JL, Zhang L, Cuttat R, Waldt A, Carballido-Perrig N, Nigsch F, Kinzel B, Nicholson TB, Yang Y, Mao X, Terracciano LM, Russ C, Reece-Hoyes JS, Gubser Keller C, Sailer AW, Bouwmeester T, Greenbaum LE, Lugus JJ, Cong F, McAllister G, Hoffman GR, Roma G, Tchorz JS.

Cell Stem Cell. 2019 Jul 3;25(1):39-53.e10. doi: 10.1016/j.stem.2019.04.005. Epub 2019 May 9.

PMID:
31080135
6.

Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes.

Ihry RJ, Salick MR, Ho DJ, Sondey M, Kommineni S, Paula S, Raymond J, Henry B, Frias E, Wang Q, Worringer KA, Ye C, Russ C, Reece-Hoyes JS, Altshuler RC, Randhawa R, Yang Z, McAllister G, Hoffman GR, Dolmetsch R, Kaykas A.

Cell Rep. 2019 Apr 9;27(2):616-630.e6. doi: 10.1016/j.celrep.2019.03.043.

7.

Bile acid analogues are activators of pyrin inflammasome.

Alimov I, Menon S, Cochran N, Maher R, Wang Q, Alford J, Concannon JB, Yang Z, Harrington E, Llamas L, Lindeman A, Hoffman G, Schuhmann T, Russ C, Reece-Hoyes J, Canham SM, Cai X.

J Biol Chem. 2019 Mar 8;294(10):3359-3366. doi: 10.1074/jbc.RA118.005103. Epub 2019 Jan 15.

8.

Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.

PMID:
30643281
9.

mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level.

Zeng H, Lu B, Zamponi R, Yang Z, Wetzel K, Loureiro J, Mohammadi S, Beibel M, Bergling S, Reece-Hoyes J, Russ C, Roma G, Tchorz JS, Capodieci P, Cong F.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10362-E10369. doi: 10.1073/pnas.1808575115. Epub 2018 Oct 8.

10.

Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction.

Ji L, Lu B, Wang Z, Yang Z, Reece-Hoyes J, Russ C, Xu W, Cong F.

Mol Cell. 2018 Oct 4;72(1):37-47.e4. doi: 10.1016/j.molcel.2018.07.040. Epub 2018 Sep 6.

11.

TMEM41B is a novel regulator of autophagy and lipid mobilization.

Moretti F, Bergman P, Dodgson S, Marcellin D, Claerr I, Goodwin JM, DeJesus R, Kang Z, Antczak C, Begue D, Bonenfant D, Graff A, Genoud C, Reece-Hoyes JS, Russ C, Yang Z, Hoffman GR, Mueller M, Murphy LO, Xavier RJ, Nyfeler B.

EMBO Rep. 2018 Sep;19(9). pii: e45889. doi: 10.15252/embr.201845889. Epub 2018 Aug 20.

12.

Gateway-Compatible Yeast One-Hybrid and Two-Hybrid Assays.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jul 2;2018(7). doi: 10.1101/pdb.top094953.

PMID:
29967278
13.

High-Efficiency Yeast Transformation.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jul 2;2018(7). doi: 10.1101/pdb.prot094995.

PMID:
29967274
14.

Identifying Interactors from an Activation Domain Prey Library.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jul 2;2018(7). doi: 10.1101/pdb.prot094987.

PMID:
29967273
15.

Generating Yeast Two-Hybrid Bait Strains.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jul 2;2018(7). doi: 10.1101/pdb.prot094979.

PMID:
29967272
16.

Generating Yeast One-Hybrid DNA-Bait Strains.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jul 2;2018(7). doi: 10.1101/pdb.prot094961.

PMID:
29967271
17.

p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells.

Ihry RJ, Worringer KA, Salick MR, Frias E, Ho D, Theriault K, Kommineni S, Chen J, Sondey M, Ye C, Randhawa R, Kulkarni T, Yang Z, McAllister G, Russ C, Reece-Hoyes J, Forrester W, Hoffman GR, Dolmetsch R, Kaykas A.

Nat Med. 2018 Jul;24(7):939-946. doi: 10.1038/s41591-018-0050-6. Epub 2018 Jun 11.

PMID:
29892062
18.

TRRAP is a central regulator of human multiciliated cell formation.

Wang Z, Plasschaert LW, Aryal S, Renaud NA, Yang Z, Choo-Wing R, Pessotti AD, Kirkpatrick ND, Cochran NR, Carbone W, Maher R, Lindeman A, Russ C, Reece-Hoyes J, McAllister G, Hoffman GR, Roma G, Jaffe AB.

J Cell Biol. 2018 Jun 4;217(6):1941-1955. doi: 10.1083/jcb.201706106. Epub 2018 Mar 27.

19.

Gateway Recombinational Cloning.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jan 2;2018(1). doi: 10.1101/pdb.top094912.

20.

Using Multisite LR Cloning to Generate a Destination Clone.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jan 2;2018(1). doi: 10.1101/pdb.prot094946.

21.

Generating an Open Reading Frame (ORF) Entry Clone and Destination Clone.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jan 2;2018(1). doi: 10.1101/pdb.prot094938.

PMID:
29295905
22.

Propagating Gateway Vectors.

Reece-Hoyes JS, Walhout AJM.

Cold Spring Harb Protoc. 2018 Jan 2;2018(1). doi: 10.1101/pdb.prot094920.

23.

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy.

Potting C, Crochemore C, Moretti F, Nigsch F, Schmidt I, Manneville C, Carbone W, Knehr J, DeJesus R, Lindeman A, Maher R, Russ C, McAllister G, Reece-Hoyes JS, Hoffman GR, Roma G, Müller M, Sailer AW, Helliwell SB.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E180-E189. doi: 10.1073/pnas.1711023115. Epub 2017 Dec 21. Erratum in: Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8579.

24.

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

Michlits G, Hubmann M, Wu SH, Vainorius G, Budusan E, Zhuk S, Burkard TR, Novatchkova M, Aichinger M, Lu Y, Reece-Hoyes J, Nitsch R, Schramek D, Hoepfner D, Elling U.

Nat Methods. 2017 Dec;14(12):1191-1197. doi: 10.1038/nmeth.4466. Epub 2017 Oct 16.

PMID:
29039415
25.

Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization.

Surdziel E, Clay I, Nigsch F, Thiemeyer A, Allard C, Hoffman G, Reece-Hoyes JS, Phadke T, Gambert R, Keller CG, Ludwig MG, Baumgarten B, Frederiksen M, Schübeler D, Seuwen K, Bouwmeester T, Fodor BD.

PLoS One. 2017 Aug 24;12(8):e0183679. doi: 10.1371/journal.pone.0183679. eCollection 2017.

26.

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D.

Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728.

27.

Gene-Centered Yeast One-Hybrid Assays.

Fuxman Bass JI, Reece-Hoyes JS, Walhout AJ.

Cold Spring Harb Protoc. 2016 Dec 1;2016(12). doi: 10.1101/pdb.top077669.

28.

Zymolyase-Treatment and Polymerase Chain Reaction Amplification from Genomic and Plasmid Templates from Yeast.

Fuxman Bass JI, Reece-Hoyes JS, Walhout AJ.

Cold Spring Harb Protoc. 2016 Dec 1;2016(12). doi: 10.1101/pdb.prot088971.

29.

Colony Lift Colorimetric Assay for β-Galactosidase Activity.

Fuxman Bass JI, Reece-Hoyes JS, Walhout AJ.

Cold Spring Harb Protoc. 2016 Dec 1;2016(12). doi: 10.1101/pdb.prot088963.

30.

Performing Yeast One-Hybrid Library Screens.

Fuxman Bass JI, Reece-Hoyes JS, Walhout AJ.

Cold Spring Harb Protoc. 2016 Dec 1;2016(12). doi: 10.1101/pdb.prot088955.

31.

Generating Bait Strains for Yeast One-Hybrid Assays.

Fuxman Bass JI, Reece-Hoyes JS, Walhout AJ.

Cold Spring Harb Protoc. 2016 Dec 1;2016(12). doi: 10.1101/pdb.prot088948.

32.

A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions.

Fuxman Bass JI, Pons C, Kozlowski L, Reece-Hoyes JS, Shrestha S, Holdorf AD, Mori A, Myers CL, Walhout AJ.

Mol Syst Biol. 2016 Oct 24;12(10):884. doi: 10.15252/msb.20167131.

33.

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.

van Overbeek M, Capurso D, Carter MM, Thompson MS, Frias E, Russ C, Reece-Hoyes JS, Nye C, Gradia S, Vidal B, Zheng J, Hoffman GR, Fuller CK, May AP.

Mol Cell. 2016 Aug 18;63(4):633-646. doi: 10.1016/j.molcel.2016.06.037. Epub 2016 Aug 4.

34.

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62.

DeJesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, Frias E, Alford J, Reece-Hoyes JS, Lindeman A, Kelliher J, Russ C, Knehr J, Carbone W, Beibel M, Roma G, Ng A, Tallarico JA, Porter JA, Xavier RJ, Mickanin C, Murphy LO, Hoffman GR, Nyfeler B.

Elife. 2016 Jun 28;5. pii: e17290. doi: 10.7554/eLife.17290.

35.

Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling.

Wang H, Lu B, Castillo J, Zhang Y, Yang Z, McAllister G, Lindeman A, Reece-Hoyes J, Tallarico J, Russ C, Hoffman G, Xu W, Schirle M, Cong F.

J Biol Chem. 2016 Jul 15;291(29):15256-66. doi: 10.1074/jbc.M116.722967. Epub 2016 May 26.

36.

Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities.

Narasimhan K, Lambert SA, Yang AW, Riddell J, Mnaimneh S, Zheng H, Albu M, Najafabadi HS, Reece-Hoyes JS, Fuxman Bass JI, Walhout AJ, Weirauch MT, Hughes TR.

Elife. 2015 Apr 23;4. doi: 10.7554/eLife.06967.

37.

Determination and inference of eukaryotic transcription factor sequence specificity.

Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, Walhout AJM, Bouget FY, Ratsch G, Larrondo LF, Ecker JR, Hughes TR.

Cell. 2014 Sep 11;158(6):1431-1443. doi: 10.1016/j.cell.2014.08.009.

39.

Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters.

Fuxman Bass JI, Tamburino AM, Mori A, Beittel N, Weirauch MT, Reece-Hoyes JS, Walhout AJ.

Nucleic Acids Res. 2014 Jan;42(1):153-62. doi: 10.1093/nar/gkt858. Epub 2013 Sep 24.

40.

Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network.

Reece-Hoyes JS, Pons C, Diallo A, Mori A, Shrestha S, Kadreppa S, Nelson J, Diprima S, Dricot A, Lajoie BR, Ribeiro PS, Weirauch MT, Hill DE, Hughes TR, Myers CL, Walhout AJ.

Mol Cell. 2013 Jul 11;51(1):116-27. doi: 10.1016/j.molcel.2013.05.018. Epub 2013 Jun 20.

41.

Yeast one-hybrid assays: a historical and technical perspective.

Reece-Hoyes JS, Marian Walhout AJ.

Methods. 2012 Aug;57(4):441-7. doi: 10.1016/j.ymeth.2012.07.027. Epub 2012 Aug 3. Review.

42.

Gene-centered yeast one-hybrid assays.

Reece-Hoyes JS, Walhout AJ.

Methods Mol Biol. 2012;812:189-208. doi: 10.1007/978-1-61779-455-1_11.

43.

A regulatory cascade of three transcription factors in a single specific neuron, DVC, in Caenorhabditis elegans.

Feng H, Reece-Hoyes JS, Walhout AJ, Hope IA.

Gene. 2012 Feb 15;494(1):73-84. doi: 10.1016/j.gene.2011.11.042. Epub 2011 Dec 19.

44.

Enhanced Y1H assays for Arabidopsis.

Gaudinier A, Zhang L, Reece-Hoyes JS, Taylor-Teeples M, Pu L, Liu Z, Breton G, Pruneda-Paz JL, Kim D, Kay SA, Walhout AJ, Ware D, Brady SM.

Nat Methods. 2011 Oct 30;8(12):1053-5. doi: 10.1038/nmeth.1750.

45.

Enhanced yeast one-hybrid assays for high-throughput gene-centered regulatory network mapping.

Reece-Hoyes JS, Diallo A, Lajoie B, Kent A, Shrestha S, Kadreppa S, Pesyna C, Dekker J, Myers CL, Walhout AJ.

Nat Methods. 2011 Oct 30;8(12):1059-64. doi: 10.1038/nmeth.1748.

46.

Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.

Reece-Hoyes JS, Barutcu AR, McCord RP, Jeong JS, Jiang L, MacWilliams A, Yang X, Salehi-Ashtiani K, Hill DE, Blackshaw S, Zhu H, Dekker J, Walhout AJ.

Nat Methods. 2011 Oct 30;8(12):1050-2. doi: 10.1038/nmeth.1764.

47.

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO.

Schuster E, McElwee JJ, Tullet JM, Doonan R, Matthijssens F, Reece-Hoyes JS, Hope IA, Vanfleteren JR, Thornton JM, Gems D.

Mol Syst Biol. 2010 Aug 10;6:399. doi: 10.1038/msb.2010.54.

48.

The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors.

Reece-Hoyes JS, Deplancke B, Barrasa MI, Hatzold J, Smit RB, Arda HE, Pope PA, Gaudet J, Conradt B, Walhout AJ.

Nucleic Acids Res. 2009 Jun;37(11):3689-98. doi: 10.1093/nar/gkp232. Epub 2009 Apr 16.

49.

Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity.

Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ.

Genome Res. 2008 Dec;18(12):2005-15. doi: 10.1101/gr.083055.108. Epub 2008 Nov 3.

50.

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping.

Vermeirssen V, Deplancke B, Barrasa MI, Reece-Hoyes JS, Arda HE, Grove CA, Martinez NJ, Sequerra R, Doucette-Stamm L, Brent MR, Walhout AJ.

Nat Methods. 2007 Aug;4(8):659-64. Epub 2007 Jun 24.

PMID:
17589517

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