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Items: 7

1.

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.

Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL.

EMBO J. 2018 Mar 1;37(5). pii: e97452. doi: 10.15252/embj.201797452. Epub 2018 Feb 9.

2.

Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function.

Li W, Reeb AN, Lin B, Subramanian P, Fey EE, Knoverek CR, French RL, Bigio EH, Ayala YM.

J Biol Chem. 2017 Mar 24;292(12):5089-5100. doi: 10.1074/jbc.M116.753913. Epub 2017 Feb 6.

3.

Characterization of human follicular thyroid cancer cell lines in preclinical mouse models.

Reeb AN, Ziegler A, Lin RY.

Endocr Connect. 2016 Mar;5(2):47-54. doi: 10.1530/EC-15-0114. Epub 2016 Feb 1.

4.

S100A8 is a novel therapeutic target for anaplastic thyroid carcinoma.

Reeb AN, Li W, Sewell W, Marlow LA, Tun HW, Smallridge RC, Copland JA, Spradling K, Chernock R, Lin RY.

J Clin Endocrinol Metab. 2015 Feb;100(2):E232-42. doi: 10.1210/jc.2014-2988. Epub 2014 Nov 25.

5.

Bioluminescent human thyrospheres allow noninvasive detection of anaplastic thyroid cancer growth and metastases in vivo.

Reeb AN, Li W, Lin RY.

Thyroid. 2014 Jul;24(7):1134-8. doi: 10.1089/thy.2014.0014. Epub 2014 May 20.

6.

Phenotypic characterization of metastatic anaplastic thyroid cancer stem cells.

Li W, Reeb AN, Sewell WA, Elhomsy G, Lin RY.

PLoS One. 2013 May 28;8(5):e65095. doi: 10.1371/journal.pone.0065095. Print 2013.

7.

The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling.

Schramm C, Fine DM, Edwards MA, Reeb AN, Krenz M.

Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H231-43. doi: 10.1152/ajpheart.00665.2011. Epub 2011 Nov 4.

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