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Redegeld FA.

Eur J Pharmacol. 2018 Nov 5;838:112. doi: 10.1016/j.ejphar.2018.09.017. Epub 2018 Sep 13. No abstract available.


Role of Mast Cells in Shaping the Tumor Microenvironment.

Komi DEA, Redegeld FA.

Clin Rev Allergy Immunol. 2019 Jun 29. doi: 10.1007/s12016-019-08753-w. [Epub ahead of print] Review.


A Transcriptomic Insight into the Impact of Colon Cancer Cells on Mast Cells.

Yu Y, Blokhuis BR, Garssen J, Redegeld FA.

Int J Mol Sci. 2019 Apr 4;20(7). pii: E1689. doi: 10.3390/ijms20071689.


Proline-Glycine-Proline Peptides Are Critical in the Development of Smoke-Induced Emphysema.

Abdul Roda M, Xu X, Abdalla TH, Sadik M, Szul T, Bratcher PE, Viera L, Solomon GM, Wells JM, McNicholas CM, Redegeld FA, Folkerts G, Blalock JE, Gaggar A.

Am J Respir Cell Mol Biol. 2019 Apr 8. doi: 10.1165/rcmb.2018-0216OC. [Epub ahead of print]


AllergoOncology: Microbiota in allergy and cancer-A European Academy for Allergy and Clinical Immunology position paper.

Untersmayr E, Bax HJ, Bergmann C, Bianchini R, Cozen W, Gould HJ, Hartmann K, Josephs DH, Levi-Schaffer F, Penichet ML, O'Mahony L, Poli A, Redegeld FA, Roth-Walter F, Turner MC, Vangelista L, Karagiannis SN, Jensen-Jarolim E.

Allergy. 2019 Jun;74(6):1037-1051. doi: 10.1111/all.13718. Epub 2019 Mar 6.


Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper.

Roth-Walter F, Adcock IM, Benito-Villalvilla C, Bianchini R, Bjermer L, Caramori G, Cari L, Chung KF, Diamant Z, Eguiluz-Gracia I, Knol EF, Kolios AGA, Levi-Schaffer F, Nocentini G, Palomares O, Puzzovio PG, Redegeld FA, van Esch BCAM, Stellato C.

Allergy. 2019 Mar;74(3):432-448. doi: 10.1111/all.13642. Epub 2019 Jan 8.


Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells.

Yu Y, Blokhuis BRJ, Diks MAP, Keshavarzian A, Garssen J, Redegeld FA.

Front Immunol. 2018 Sep 20;9:2138. doi: 10.3389/fimmu.2018.02138. eCollection 2018.


Predictable Irreversible Switching Between Acute and Chronic Inflammation.

Abudukelimu A, Barberis M, Redegeld FA, Sahin N, Westerhoff HV.

Front Immunol. 2018 Aug 7;9:1596. doi: 10.3389/fimmu.2018.01596. eCollection 2018.


Effect of Dietary Fiber and Metabolites on Mast Cell Activation and Mast Cell-Associated Diseases.

Folkerts J, Stadhouders R, Redegeld FA, Tam SY, Hendriks RW, Galli SJ, Maurer M.

Front Immunol. 2018 May 29;9:1067. doi: 10.3389/fimmu.2018.01067. eCollection 2018. Review.


Effects of the polyunsaturated fatty acids, EPA and DHA, on hematological malignancies: a systematic review.

Moloudizargari M, Mortaz E, Asghari MH, Adcock IM, Redegeld FA, Garssen J.

Oncotarget. 2018 Feb 5;9(14):11858-11875. doi: 10.18632/oncotarget.24405. eCollection 2018 Feb 20. Review.


Non-IgE mediated mast cell activation.

Redegeld FA, Yu Y, Kumari S, Charles N, Blank U.

Immunol Rev. 2018 Mar;282(1):87-113. doi: 10.1111/imr.12629. Review.


Mast Cells as Drivers of Disease and Therapeutic Targets.

Siebenhaar F, Redegeld FA, Bischoff SC, Gibbs BF, Maurer M.

Trends Immunol. 2018 Feb;39(2):151-162. doi: 10.1016/ Epub 2017 Nov 28. Review.


'Corrigendum to "Mast cells in neuroinflammation and brain disorders"[Neurosci. Biobehav. Rev. 79 (2017) 119-133]'.

Hendrikus E, van Bergeijk DA, Oosting RS, Redegeld FA.

Neurosci Biobehav Rev. 2017 Dec;83:774. doi: 10.1016/j.neubiorev.2017.10.030. Epub 2017 Nov 2. No abstract available.


Immunoglobulin Free Light Chains in the Pathogenesis of Lung Disorders.

Mortaz E, Adcock IM, Jamaati H, Khosravi A, Movassaghi M, Garssen J, Alavi Mogadam M, Redegeld FA.

Iran J Allergy Asthma Immunol. 2017 Aug;16(4):282-288. Review.


Human neonatal thymectomy induces altered B-cell responses and autoreactivity.

van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F.

Eur J Immunol. 2017 Nov;47(11):1970-1981. doi: 10.1002/eji.201746971. Epub 2017 Sep 6.


Mast cells in neuroinflammation and brain disorders.

Hendriksen E, van Bergeijk D, Oosting RS, Redegeld FA.

Neurosci Biobehav Rev. 2017 Aug;79:119-133. doi: 10.1016/j.neubiorev.2017.05.001. Epub 2017 May 10. Review. Erratum in: Neurosci Biobehav Rev. 2017 Dec;83:774.


Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.

van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH.

Mol Cell Proteomics. 2016 Nov;15(11):3412-3423. Epub 2016 Sep 6.


Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell-Specific Proteases.

Groot Kormelink T, Arkesteijn GJ, van de Lest CH, Geerts WJ, Goerdayal SS, Altelaar MA, Redegeld FA, Nolte-'t Hoen EN, Wauben MH.

J Immunol. 2016 Oct 15;197(8):3382-3392. Epub 2016 Sep 12.


Cigarette smoke differentially modulates dendritic cell maturation and function in time.

Givi ME, Folkerts G, Wagenaar GT, Redegeld FA, Mortaz E.

Respir Res. 2015 Oct 24;16:131. doi: 10.1186/s12931-015-0291-6.


Dendritic cells inversely regulate airway inflammation in cigarette smoke-exposed mice.

Givi ME, Akbari P, Boon L, Puzovic VS, Bezemer GF, Ricciardolo FL, Folkerts G, Redegeld FA, Mortaz E.

Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L95-102. doi: 10.1152/ajplung.00251.2014. Epub 2015 Oct 16.


The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability.

Hahn CS, Scott DW, Xu X, Roda MA, Payne GA, Wells JM, Viera L, Winstead CJ, Bratcher P, Sparidans RW, Redegeld FA, Jackson PL, Folkerts G, Blalock JE, Patel RP, Gaggar A.

Sci Adv. 2015;1(3). pii: e1500175.


Non-IgE mediated mast cell activation.

Yu Y, Blokhuis BR, Garssen J, Redegeld FA.

Eur J Pharmacol. 2016 May 5;778:33-43. doi: 10.1016/j.ejphar.2015.07.017. Epub 2015 Jul 8. Review.


The matrikine PGP as a potential biomarker in COPD.

Abdul Roda M, Fernstrand AM, Redegeld FA, Blalock JE, Gaggar A, Folkerts G.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 1;308(11):L1095-101. doi: 10.1152/ajplung.00040.2015. Epub 2015 Apr 10. Review.


Association of serum TNF-α, IL-8 and free light chain with HLA-DR B alleles expression in pulmonary and extra-pulmonary sarcoidosis.

Mortaz E, Sereshki HA, Abedini A, Kiani A, Mirsaeidi M, Soroush D, Garssen J, Velayati A, Redegeld FA, Adcock IM.

J Inflamm (Lond). 2015 Mar 19;12:21. doi: 10.1186/s12950-015-0066-3. eCollection 2015.


Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.

Abdi J, Garssen J, Faber J, Redegeld FA.

J Nutr Biochem. 2014 Dec;25(12):1254-62. doi: 10.1016/j.jnutbio.2014.06.013. Epub 2014 Sep 6.


Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures.

Zonneveld MI, Brisson AR, van Herwijnen MJ, Tan S, van de Lest CH, Redegeld FA, Garssen J, Wauben MH, Nolte-'t Hoen EN.

J Extracell Vesicles. 2014 Aug 14;3. doi: 10.3402/jev.v3.24215. eCollection 2014.


Measurement of airway function using invasive and non-invasive methods in mild and severe models for allergic airway inflammation in mice.

Verheijden KA, Henricks PA, Redegeld FA, Garssen J, Folkerts G.

Front Pharmacol. 2014 Aug 12;5:190. doi: 10.3389/fphar.2014.00190. eCollection 2014.


Basophil-derived amphiregulin is essential for UVB irradiation-induced immune suppression.

Meulenbroeks C, van Weelden H, Schwartz C, Voehringer D, Redegeld FAM, Rutten VPMG, Willemse T, Sijts AJAM, Zaiss DMW.

J Invest Dermatol. 2015 Jan;135(1):222-228. doi: 10.1038/jid.2014.329. Epub 2014 Jul 4.


Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation.

Groot Kormelink T, Powe DG, Kuijpers SA, Abudukelimu A, Fens MH, Pieters EH, Kassing van der Ven WW, Habashy HO, Ellis IO, Blokhuis BR, Thio M, Hennink WE, Storm G, Redegeld FA, Schiffelers RM.

Oncotarget. 2014 May 30;5(10):3159-67.


Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation.

Abdul Roda M, Sadik M, Gaggar A, Hardison MT, Jablonsky MJ, Braber S, Blalock JE, Redegeld FA, Folkerts G, Jackson PL.

PLoS One. 2014 May 16;9(5):e97594. doi: 10.1371/journal.pone.0097594. eCollection 2014.


Toll-like receptor (TLR)-1/2 triggering of multiple myeloma cells modulates their adhesion to bone marrow stromal cells and enhances bortezomib-induced apoptosis.

Abdi J, Mutis T, Garssen J, Redegeld FA.

PLoS One. 2014 May 2;9(5):e96608. doi: 10.1371/journal.pone.0096608. eCollection 2014.


Immunoglobulinfree light chains reduce in an antigen-specific manner the rate of rise of action potentials of mouse non-nociceptive dorsal root ganglion neurons.

Rijnierse A, Kraneveld AD, Salemi A, Zwaneveld S, Goumans AP, Rychter JW, Thio M, Redegeld FA, Westerink RH, Kroese AB.

J Neuroimmunol. 2013 Nov 15;264(1-2):14-23. doi: 10.1016/j.jneuroim.2013.08.015. Epub 2013 Aug 31.


Cigarette smoke suppresses the surface expression of c-kit and FcεRI on mast cells.

Givi ME, Blokhuis BR, Da Silva CA, Adcock I, Garssen J, Folkerts G, Redegeld FA, Mortaz E.

Mediators Inflamm. 2013;2013:813091. doi: 10.1155/2013/813091. Epub 2013 Feb 12.


Polyclonal immunoglobulin free light chain and chronic inflammation.

Redegeld FA, Thio M, Groot Kormelink T.

Mayo Clin Proc. 2012 Oct;87(10):1032-3; author reply 1033. doi: 10.1016/j.mayocp.2012.07.012. No abstract available.


n-3 Long-chain PUFA reduce allergy-related mediator release by human mast cells in vitro via inhibition of reactive oxygen species.

van den Elsen LW, Nusse Y, Balvers M, Redegeld FA, Knol EF, Garssen J, Willemsen LE.

Br J Nutr. 2013 May 28;109(10):1821-31. doi: 10.1017/S0007114512003959. Epub 2012 Oct 1.


Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.

Thio M, Groot Kormelink T, Fischer MJ, Blokhuis BR, Nijkamp FP, Redegeld FA.

PLoS One. 2012;7(7):e40986. doi: 10.1371/journal.pone.0040986. Epub 2012 Jul 20.


Local free light chain expression is increased in chronic rhinosinusitis with nasal polyps.

Groot Kormelink T, Calus L, De Ruyck N, Holtappels G, Bachert C, Redegeld FA, Gevaert P.

Allergy. 2012 Sep;67(9):1165-72. doi: 10.1111/j.1398-9995.2012.02866.x. Epub 2012 Jul 5.


A relation between TGF-β and mast cell tryptase in experimental emphysema models.

Mortaz E, Givi ME, Da Silva CA, Folkerts G, Redegeld FA.

Biochim Biophys Acta. 2012 Jul;1822(7):1154-60. doi: 10.1016/j.bbadis.2012.03.006. Epub 2012 Mar 22.


Dendritic cells in pathogenesis of COPD.

Givi ME, Redegeld FA, Folkerts G, Mortaz E.

Curr Pharm Des. 2012;18(16):2329-35. Review.


Immunobiology of antigen-specific immunoglobulin free light chains in chronic inflammatory diseases.

Groot Kormelink T, Askenase PW, Redegeld FA.

Curr Pharm Des. 2012;18(16):2278-89. Review.


Editorial: modulation and new mediators in inflammation.

Redegeld FA.

Curr Pharm Des. 2012;18(16):2259-60. No abstract available.


An association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease.

Braber S, Thio M, Blokhuis BR, Henricks PA, Koelink PJ, Groot Kormelink T, Bezemer GF, Kerstjens HA, Postma DS, Garssen J, Kraneveld AD, Redegeld FA, Folkerts G.

Am J Respir Crit Care Med. 2012 Apr 15;185(8):817-24. doi: 10.1164/rccm.201104-0761OC. Epub 2012 Jan 6.


Immunoglobulin free light chains are increased in hypersensitivity pneumonitis and idiopathic pulmonary fibrosis.

Groot Kormelink T, Pardo A, Knipping K, Buendía-Roldán I, García-de-Alba C, Blokhuis BR, Selman M, Redegeld FA.

PLoS One. 2011;6(9):e25392. doi: 10.1371/journal.pone.0025392. Epub 2011 Sep 28.


Non-digestible oligosaccharides reduce immunoglobulin free light-chain concentrations in infants at risk for allergy.

Schouten B, Van Esch BC, Kormelink TG, Moro GE, Arslanoglu S, Boehm G, Knippels LM, Redegeld FA, Willemsen LE, Garssen J.

Pediatr Allergy Immunol. 2011 Aug;22(5):537-42. doi: 10.1111/j.1399-3038.2010.01132.x.


Toll-like receptor-9 triggering modulates expression of α-4 integrin on human B lymphocytes and their adhesion to extracellular matrix proteins.

Abdi J, Engels F, Garssen J, Redegeld FA.

Exp Hematol. 2011 Sep;39(9):927-33. doi: 10.1016/j.exphem.2011.05.011. Epub 2011 Jun 12.


Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity.

Kormelink TG, Tekstra J, Thurlings RM, Boumans MH, Vos K, Tak PP, Bijlsma JW, Lafeber FP, Redegeld FA, van Roon JA.

Ann Rheum Dis. 2010 Dec;69(12):2137-44. doi: 10.1136/ard.2009.126441. Epub 2010 Aug 2.


Ig-free light chains play a crucial role in murine mast cell-dependent colitis and are associated with human inflammatory bowel diseases.

Rijnierse A, Redegeld FA, Blokhuis BR, Van der Heijden MW, Te Velde AA, Pronk I, Hommes DW, Nijkamp FP, Koster AS, Kraneveld AD.

J Immunol. 2010 Jul 1;185(1):653-9. doi: 10.4049/jimmunol.0901129. Epub 2010 May 26.


Contribution of IgE and immunoglobulin free light chain in the allergic reaction to cow's milk proteins.

Schouten B, van Esch BC, van Thuijl AO, Blokhuis BR, Groot Kormelink T, Hofman GA, Moro GE, Boehm G, Arslanoglu S, Sprikkelman AB, Willemsen LE, Knippels LM, Redegeld FA, Garssen J.

J Allergy Clin Immunol. 2010 Jun;125(6):1308-14. doi: 10.1016/j.jaci.2010.02.039.


Depletion of CD4+CD25+ T cells switches the whey-allergic response from immunoglobulin E- to immunoglobulin free light chain-dependent.

van Esch BC, Schouten B, Blokhuis BR, Hofman GA, Boon L, Garssen J, Knippels LM, Willemsen LE, Redegeld FA.

Clin Exp Allergy. 2010 Sep;40(9):1414-21. doi: 10.1111/j.1365-2222.2010.03500.x. Epub 2010 Apr 19.


Effects of free immunoglobulin light chains on viral myocarditis.

Matsumori A, Shimada M, Jie X, Higuchi H, Groot Kormelink T, Redegeld FA.

Circ Res. 2010 May 14;106(9):1533-40. doi: 10.1161/CIRCRESAHA.110.218438. Epub 2010 Apr 1.


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