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Items: 1 to 50 of 227

1.

Total Synthesis and Biological Evaluation of Cell Adhesion Inhibitors Peribysin A and B: Structural Revision of Peribysin B.

Kalmode HP, Handore KL, Rajput R, Shaikh SR, Gonnade RG, Kulkarni KA, Reddy DS.

Org Lett. 2018 Oct 26. doi: 10.1021/acs.orglett.8b02838. [Epub ahead of print]

PMID:
30362357
2.

A General Diastereoselective Strategy for Both cis- and trans-2,6-Disubstituted Tetrahydropyrans: Formal Total Synthesis of (+)-Muconin.

Srinivas B, Reddy DS, Mallampudi NA, Mohapatra DK.

Org Lett. 2018 Nov 2;20(21):6910-6914. doi: 10.1021/acs.orglett.8b03053. Epub 2018 Oct 24.

PMID:
30354147
3.

Neuroendocrine aspects of improving sleep in epilepsy.

Reddy DS, Chuang SH, Hunn D, Crepeau AZ, Maganti R.

Epilepsy Res. 2018 Nov;147:32-41. doi: 10.1016/j.eplepsyres.2018.08.013. Epub 2018 Aug 31. Review.

PMID:
30212766
4.

CD4 cell counts and oral manifestations in HIV infected and AIDS patients.

Ratnam M, Nayyar AS, Reddy DS, Ruparani B, Chalapathi KV, Azmi SM.

J Oral Maxillofac Pathol. 2018 May-Aug;22(2):282. doi: 10.4103/jomfp.JOMFP_191_17.

5.

Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents.

Wu X, Kuruba R, Reddy DS.

J Pharmacol Exp Ther. 2018 Nov;367(2):302-321. doi: 10.1124/jpet.117.247106. Epub 2018 Aug 16.

PMID:
30115757
6.

Efforts To Access the Potent Antitrypanosomal Marine Natural Product Janadolide: Synthesis of Des-tert-butyl Janadolide and Its Biological Evaluation.

Athawale PR, Jachak GR, Shukla A, Shanmugam D, Reddy DS.

ACS Omega. 2018 Feb 28;3(2):2383-2389. doi: 10.1021/acsomega.7b01920. Epub 2018 Feb 27.

8.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2018 Jul 13. doi: 10.1039/c7np00064b. [Epub ahead of print] Review.

PMID:
30003207
9.

Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia.

Verma AK, Waghmare TS, Jachak GR, Philkhana SC, Reddy DS, Basu A.

PLoS Negl Trop Dis. 2018 Jul 12;12(7):e0006648. doi: 10.1371/journal.pntd.0006648. eCollection 2018 Jul.

10.

A novel biocompatible NiII tethered moiety as a glucose uptake agent and a hit against methicillin-resistant Staphylococcus aureus.

Kongot M, Dohare N, Singh V, Reddy DS, Singhal NK, Patel R, Kumar A.

Eur J Pharm Sci. 2018 Oct 15;123:335-349. doi: 10.1016/j.ejps.2018.07.008. Epub 2018 Jul 5.

PMID:
29981891
11.

Effect of combination therapy with pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury in rats.

Danduga RCSR, Reddy DS, Seshadri SM, Has KSS, Kumar KP.

Iran J Basic Med Sci. 2018 Jun;21(6):569-576. doi: 10.22038/IJBMS.2018.22647.5756.

12.

Measuring Histone Deacetylase Inhibition in the Brain.

Reddy DS, Wu X, Golub VM, Dashwood WM, Dashwood RH.

Curr Protoc Pharmacol. 2018 Jun;81(1):e41. doi: 10.1002/cpph.41. Epub 2018 Jun 7.

PMID:
29927058
13.

Benzodiazepine-refractory status epilepticus, neuroinflammation, and interneuron neurodegeneration after acute organophosphate intoxication.

Kuruba R, Wu X, Reddy DS.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2845-2858. doi: 10.1016/j.bbadis.2018.05.016. Epub 2018 May 23.

PMID:
29802961
14.

Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite.

Das P, Babbar P, Malhotra N, Sharma M, Jachak GR, Gonnade RG, Shanmugam D, Harlos K, Yogavel M, Sharma A, Reddy DS.

J Med Chem. 2018 Jul 12;61(13):5664-5678. doi: 10.1021/acs.jmedchem.8b00565. Epub 2018 Jun 4.

PMID:
29779382
15.

Copper(II)nitrate catalyzed regioselective protection of primary alcohols with 4,4'-dimethoxytrityl and 2,7-dimethyl-9-phenyl xanthen-9-yl groups in nucleosides and carbohydrates.

Penjarla S, Prasad SR, Reddy DS, Banerjee S, Penta S, Sanghvi YS.

Nucleosides Nucleotides Nucleic Acids. 2018;37(4):232-247. doi: 10.1080/15257770.2018.1460480. Epub 2018 May 3.

PMID:
29723125
16.

Removal of lead and fluoride from contaminated water using exhausted coffee grounds based bio-sorbent.

Naga Babu A, Reddy DS, Kumar GS, Ravindhranath K, Krishna Mohan GV.

J Environ Manage. 2018 Jul 15;218:602-612. doi: 10.1016/j.jenvman.2018.04.091. Epub 2018 Apr 30.

PMID:
29715669
17.

A novel mitochondrial orf147 causes cytoplasmic male sterility in pigeonpea by modulating aberrant anther dehiscence.

Bhatnagar-Mathur P, Gupta R, Reddy PS, Reddy BP, Reddy DS, Sameerkumar CV, Saxena RK, Sharma KK.

Plant Mol Biol. 2018 May;97(1-2):131-147. doi: 10.1007/s11103-018-0728-7. Epub 2018 Apr 17.

PMID:
29667000
18.
19.

Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agents: Their DNA cleavage ability and BSA interaction study.

Reddy DS, Kongot M, Netalkar SP, Kurjogi MM, Kumar R, Avecilla F, Kumar A.

Eur J Med Chem. 2018 Apr 25;150:864-875. doi: 10.1016/j.ejmech.2018.03.042. Epub 2018 Mar 20.

PMID:
29597169
20.

Role of β2/3-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis.

Reddy DS, Yoshimura RF, Ramanathan G, Carver C, Johnstone TB, Hogenkamp DJ, Gee KW.

Epilepsy Behav. 2018 May;82:57-63. doi: 10.1016/j.yebeh.2018.02.020. Epub 2018 Mar 26.

PMID:
29587186
21.

GABA-A Receptors Mediate Tonic Inhibition and Neurosteroid Sensitivity in the Brain.

Reddy DS.

Vitam Horm. 2018;107:177-191. doi: 10.1016/bs.vh.2017.12.001. Epub 2018 Feb 9. Review.

PMID:
29544630
22.

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2018 Jan 17;3(1). pii: e00534-17. doi: 10.1128/mSphere.00534-17. eCollection 2018 Jan-Feb.

23.

Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.

Chuang SH, Reddy DS.

J Pharmacol Exp Ther. 2018 Feb;364(2):180-197. doi: 10.1124/jpet.117.244673. Epub 2017 Nov 15.

PMID:
29142081
24.

Epigenetic Histone Deacetylation Inhibition Prevents the Development and Persistence of Temporal Lobe Epilepsy.

Reddy SD, Clossen BL, Reddy DS.

J Pharmacol Exp Ther. 2018 Jan;364(1):97-109. doi: 10.1124/jpet.117.244939. Epub 2017 Nov 3.

PMID:
29101217
25.

Atomic force microscopy investigations of fibronectin and α5β1-integrin signaling in neuroplasticity and seizure susceptibility in experimental epilepsy.

Wu X, Muthuchamy M, Reddy DS.

Epilepsy Res. 2017 Dec;138:71-80. doi: 10.1016/j.eplepsyres.2017.10.013. Epub 2017 Oct 24.

PMID:
29096132
26.

Neurocysticercosis as an infectious acquired epilepsy worldwide.

Reddy DS, Volkmer R 2nd.

Seizure. 2017 Nov;52:176-181. doi: 10.1016/j.seizure.2017.10.004. Epub 2017 Oct 7. Review.

27.

Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds.

Ramesh R, Reddy DS.

J Med Chem. 2018 May 10;61(9):3779-3798. doi: 10.1021/acs.jmedchem.7b00718. Epub 2017 Nov 1.

PMID:
29039662
28.

A resurging boom in new drugs for epilepsy and brain disorders.

Younus I, Reddy DS.

Expert Rev Clin Pharmacol. 2018 Jan;11(1):27-45. doi: 10.1080/17512433.2018.1386553. Epub 2017 Oct 23. Review.

PMID:
28956955
29.

Cytological Changes in Normal Oral Mucosa of Individuals with Tobacco Habits: A Cytomorphometric Study.

Palakurthy P, Kulkarni PG, Nandan RK, Rao TM, Reddy DSP, Muddana K.

J Contemp Dent Pract. 2017 Aug 1;18(8):722-727.

PMID:
28816197
30.

Repurposing Ivacaftor for treatment of Staphylococcus aureus infections.

Thakare R, Singh AK, Das S, Vasudevan N, Jachak GR, Reddy DS, Dasgupta A, Chopra S.

Int J Antimicrob Agents. 2017 Sep;50(3):389-392. doi: 10.1016/j.ijantimicag.2017.03.020. Epub 2017 Jul 8.

PMID:
28694231
31.

Access to Fused Tricyclic γ-Butyrolactones, A Natural Product-like Scaffold.

Kalmode HP, Handore KL, Reddy DS.

J Org Chem. 2017 Jul 21;82(14):7614-7620. doi: 10.1021/acs.joc.7b00794. Epub 2017 Jul 10.

PMID:
28636370
32.

Identification of new anti-inflammatory agents based on nitrosporeusine natural products of marine origin.

Philkhana SC, Verma AK, Jachak GR, Hazra B, Basu A, Reddy DS.

Eur J Med Chem. 2017 Jul 28;135:89-109. doi: 10.1016/j.ejmech.2017.04.015. Epub 2017 Apr 13.

PMID:
28433779
33.

Response to: 'Birth control in epilepsy: we need to know more'.

Reddy DS.

Expert Rev Neurother. 2017 Jun;17(6):523. doi: 10.1080/14737175.2017.1314183. Epub 2017 Apr 10. No abstract available.

PMID:
28359202
34.
35.

Epigenetic interventions for epileptogenesis: A new frontier for curing epilepsy.

Younus I, Reddy DS.

Pharmacol Ther. 2017 Sep;177:108-122. doi: 10.1016/j.pharmthera.2017.03.002. Epub 2017 Mar 6. Review.

36.

Identification and Synthesis of Mycalol Analogues with Improved Potency against Anaplastic Thyroid Carcinoma Cell Lines.

Cutignano A, Seetharamsingh B, D'Angelo D, Nuzzo G, Khairnar PV, Fusco A, Reddy DS, Fontana A.

J Nat Prod. 2017 Apr 28;80(4):1125-1133. doi: 10.1021/acs.jnatprod.7b00043. Epub 2017 Mar 6.

PMID:
28263603
37.

A Comparative Toxidrome Analysis of Human Organophosphate and Nerve Agent Poisonings Using Social Media.

Reddy DS, Colman E.

Clin Transl Sci. 2017 May;10(3):225-230. doi: 10.1111/cts.12435. Epub 2017 Feb 26.

38.

Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain.

Clossen BL, Reddy DS.

J Neurosci Res. 2017 Oct;95(10):1906-1916. doi: 10.1002/jnr.24028. Epub 2017 Feb 25.

39.

Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy.

Clossen BL, Reddy DS.

Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1519-1538. doi: 10.1016/j.bbadis.2017.02.003. Epub 2017 Feb 5. Review.

40.

Determination of the Absolute Configuration of Gliomasolide D through Total Syntheses of the C-17 Epimers.

Seetharamsingh B, Ganesh R, Reddy DS.

J Nat Prod. 2017 Feb 24;80(2):560-564. doi: 10.1021/acs.jnatprod.6b00926. Epub 2017 Feb 8.

PMID:
28177243
41.

PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields.

Reddy DS, Gangisetty O, Wu X.

Brain Res. 2017 Mar 15;1659:142-147. doi: 10.1016/j.brainres.2017.01.030. Epub 2017 Jan 28.

42.

Cementum as an age determinant: A forensic view.

Raju GS, Keerthi M, Nandan SR, Rao TM, Kulkarni PG, Reddy DS.

J Forensic Dent Sci. 2016 Sep-Dec;8(3):175. doi: 10.4103/0975-1475.195121.

43.

Impact of rapid molecular diagnostic tests on time to treatment initiation and outcomes in patients with multidrug-resistant tuberculosis, Tamil Nadu, India.

Nair D, Navneethapandian PD, Tripathy JP, Harries AD, Klinton JS, Watson B, Sivaramakrishnan GN, Reddy DS, Murali L, Natrajan M, Swaminathan S.

Trans R Soc Trop Med Hyg. 2016 Sep;110(9):534-541. Epub 2016 Oct 13.

PMID:
27738284
44.

Do oral contraceptives increase epileptic seizures?

Reddy DS.

Expert Rev Neurother. 2017 Feb;17(2):129-134. doi: 10.1080/14737175.2016.1243472. Epub 2016 Oct 12. Erratum in: Expert Rev Neurother. 2017 Feb;17(2):i.

45.

Structure Revision of an Acorane Sesquiterpene Cordycepol A.

Reddy DS, Kutateladze AG.

Org Lett. 2016 Oct 7;18(19):4860-4863. Epub 2016 Sep 9.

PMID:
27611774
46.

Synthesis and biological evaluation of palmyrolide A macrocycles as sodium channel blockers towards neuroprotection.

Philkhana SC, Mehrotra S, Murray TF, Reddy DS.

Org Biomol Chem. 2016 Sep 28;14(36):8457-73. doi: 10.1039/c6ob01372d. Epub 2016 Aug 18.

PMID:
27536802
47.

The Utility of Cannabidiol in the Treatment of Refractory Epilepsy.

Reddy DS.

Clin Pharmacol Ther. 2017 Feb;101(2):182-184. doi: 10.1002/cpt.441. Epub 2016 Sep 29. Review.

PMID:
27506704
48.

GSH Induced Controlled Release of Levofloxacin from a Purpose-Built Prodrug: Luminescence Response for Probing the Drug Release in Escherichia coli and Staphylococcus aureus.

Pal S, Ramu V, Taye N, Mogare DG, Yeware AM, Sarkar D, Reddy DS, Chattopadhyay S, Das A.

Bioconjug Chem. 2016 Sep 21;27(9):2062-70. doi: 10.1021/acs.bioconjchem.6b00324. Epub 2016 Aug 26.

PMID:
27506475
49.

Zinc Selectively Blocks Neurosteroid-Sensitive Extrasynaptic δGABAA Receptors in the Hippocampus.

Carver CM, Chuang SH, Reddy DS.

J Neurosci. 2016 Aug 3;36(31):8070-7. doi: 10.1523/JNEUROSCI.3393-15.2016.

50.

Prospects of modeling poststroke epileptogenesis.

Reddy DS, Bhimani A, Kuruba R, Park MJ, Sohrabji F.

J Neurosci Res. 2017 Apr;95(4):1000-1016. doi: 10.1002/jnr.23836. Epub 2016 Jul 25. Review.

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