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Items: 1 to 50 of 244

1.

Access to a Stereoisomer Library of Solomonamide Macrocycles.

Jachak GR, Athawale PR, Choudhury R, Kashinath K, Reddy DS.

Chem Asian J. 2019 Sep 11. doi: 10.1002/asia.201901075. [Epub ahead of print]

PMID:
31512378
2.

A route to access imidazol[1,5-a]indole-1,3-diones and pyrrolo[1,2-c]imidazole-1,3-diones.

Sreenivasa Rao R, Shajan FJ, Reddy DS.

Org Biomol Chem. 2019 Sep 28;17(36):8384-8390. doi: 10.1039/c9ob01462d. Epub 2019 Aug 30.

PMID:
31469149
3.

Coumarin tethered cyclic imides as efficacious glucose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin.

Reddy DS, Kongot M, Singh V, Maurya N, Patel R, Kumar Singhal N, Avecilla F, Kumar A.

Bioorg Chem. 2019 Nov;92:103212. doi: 10.1016/j.bioorg.2019.103212. Epub 2019 Aug 21.

PMID:
31465968
4.

Natural Products Containing the Oxetane and Related Moieties Present Additional Challenges for Structure Elucidation: A DU8+ Computational Case Study.

Kutateladze AG, Holt T, Reddy DS.

J Org Chem. 2019 Jun 21;84(12):7575-7586. doi: 10.1021/acs.joc.9b01005. Epub 2019 Jun 7.

PMID:
31145850
5.

Photoinitiated Cascade for Rapid Access to Pyrroloquinazolinone Core of Vasicinone, Luotonins, and Related Alkaloids.

Reddy DS, Kutateladze AG.

Org Lett. 2019 Apr 19;21(8):2855-2858. doi: 10.1021/acs.orglett.9b00858. Epub 2019 Apr 1.

PMID:
30933523
6.

An enigmatic role of tonic inhibition in gabapentin therapy.

Reddy DS.

EBioMedicine. 2019 Apr;42:14-15. doi: 10.1016/j.ebiom.2019.03.047. Epub 2019 Mar 22. No abstract available.

7.

Extrasynaptic γ-aminobutyric acid type A receptor-mediated sex differences in the antiseizure activity of neurosteroids in status epilepticus and complex partial seizures.

Reddy DS, Carver CM, Clossen B, Wu X.

Epilepsia. 2019 Apr;60(4):730-743. doi: 10.1111/epi.14693. Epub 2019 Mar 20.

PMID:
30895610
8.

Erratum for Subramanian et al., "Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules".

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2019 Mar 13;4(2). pii: e00159-19. doi: 10.1128/mSphere.00159-19. No abstract available.

9.

Neuroimaging Biomarkers of Experimental Epileptogenesis and Refractory Epilepsy.

Reddy SD, Younus I, Sridhar V, Reddy DS.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E220. doi: 10.3390/ijms20010220. Review.

10.

Multiple impacted permanent teeth, an indicator for early detection of hypoparathyroidism: A rare case report.

Reddy GS, Chalapathi KV, Reddy DS, Rana S, Kalyan M, Kartheeki B, Nayyar AS.

J Family Med Prim Care. 2018 Sep-Oct;7(5):1096-1099. doi: 10.4103/jfmpc.jfmpc_352_17.

11.

Evaluating antimalarial efficacy by tracking glycolysis in Plasmodium falciparum using NMR spectroscopy.

Shivapurkar R, Hingamire T, Kulkarni AS, Rajamohanan PR, Reddy DS, Shanmugam D.

Sci Rep. 2018 Dec 24;8(1):18076. doi: 10.1038/s41598-018-36197-3.

12.

Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation.

Jachak GR, Athawale PR, Agarwal H, Barthwal MK, Lauro G, Bifulco G, Reddy DS.

Org Biomol Chem. 2018 Dec 5;16(47):9138-9142. doi: 10.1039/c8ob02713g.

PMID:
30478463
13.

Zinc reduces antiseizure activity of neurosteroids by selective blockade of extrasynaptic GABA-A receptor-mediated tonic inhibition in the hippocampus.

Chuang SH, Reddy DS.

Neuropharmacology. 2019 Apr;148:244-256. doi: 10.1016/j.neuropharm.2018.11.031. Epub 2018 Nov 22.

PMID:
30471294
14.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

15.

In vitro apoptosis-induction, antiproliferative and BSA binding studies of a oxidovanadium(V) complex.

Kongot M, Dohare N, Reddy DS, Pereira N, Patel R, Subramanian M, Kumar A.

J Trace Elem Med Biol. 2019 Jan;51:176-190. doi: 10.1016/j.jtemb.2018.10.019. Epub 2018 Oct 28.

PMID:
30466929
16.

Enantioselective Conversion of Oligoprenol Derivatives to Macrocycles in the Germacrene, Cembrene, and 18-Membered Cyclic Sesterterpene Series.

Reddy DS, Corey EJ.

J Am Chem Soc. 2018 Dec 12;140(49):16909-16913. doi: 10.1021/jacs.8b10522. Epub 2018 Nov 28.

PMID:
30466258
17.

Compact and Programmable Ultrasound Front-End Processing Module for Research Activities.

Bharath R, Kumar P, Reddy DS, Rajalakshmi P.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:921-924. doi: 10.1109/EMBC.2018.8512343.

PMID:
30440541
18.

Total Synthesis and Biological Evaluation of Cell Adhesion Inhibitors Peribysin A and B: Structural Revision of Peribysin B.

Kalmode HP, Handore KL, Rajput R, Shaikh SR, Gonnade RG, Kulkarni KA, Reddy DS.

Org Lett. 2018 Nov 16;20(22):7003-7006. doi: 10.1021/acs.orglett.8b02838. Epub 2018 Oct 26.

PMID:
30362357
19.

A General Diastereoselective Strategy for Both cis- and trans-2,6-Disubstituted Tetrahydropyrans: Formal Total Synthesis of (+)-Muconin.

Srinivas B, Reddy DS, Mallampudi NA, Mohapatra DK.

Org Lett. 2018 Nov 2;20(21):6910-6914. doi: 10.1021/acs.orglett.8b03053. Epub 2018 Oct 24.

PMID:
30354147
20.

Neuroendocrine aspects of improving sleep in epilepsy.

Reddy DS, Chuang SH, Hunn D, Crepeau AZ, Maganti R.

Epilepsy Res. 2018 Nov;147:32-41. doi: 10.1016/j.eplepsyres.2018.08.013. Epub 2018 Aug 31. Review.

PMID:
30212766
21.

CD4 cell counts and oral manifestations in HIV infected and AIDS patients.

Ratnam M, Nayyar AS, Reddy DS, Ruparani B, Chalapathi KV, Azmi SM.

J Oral Maxillofac Pathol. 2018 May-Aug;22(2):282. doi: 10.4103/jomfp.JOMFP_191_17.

22.

Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents.

Wu X, Kuruba R, Reddy DS.

J Pharmacol Exp Ther. 2018 Nov;367(2):302-321. doi: 10.1124/jpet.117.247106. Epub 2018 Aug 16.

PMID:
30115757
23.

Efforts To Access the Potent Antitrypanosomal Marine Natural Product Janadolide: Synthesis of Des-tert-butyl Janadolide and Its Biological Evaluation.

Athawale PR, Jachak GR, Shukla A, Shanmugam D, Reddy DS.

ACS Omega. 2018 Feb 28;3(2):2383-2389. doi: 10.1021/acsomega.7b01920. Epub 2018 Feb 27.

25.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Review. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

26.

Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia.

Verma AK, Waghmare TS, Jachak GR, Philkhana SC, Reddy DS, Basu A.

PLoS Negl Trop Dis. 2018 Jul 12;12(7):e0006648. doi: 10.1371/journal.pntd.0006648. eCollection 2018 Jul.

27.

A novel biocompatible NiII tethered moiety as a glucose uptake agent and a hit against methicillin-resistant Staphylococcus aureus.

Kongot M, Dohare N, Singh V, Reddy DS, Singhal NK, Patel R, Kumar A.

Eur J Pharm Sci. 2018 Oct 15;123:335-349. doi: 10.1016/j.ejps.2018.07.008. Epub 2018 Jul 5.

PMID:
29981891
28.

Effect of combination therapy with pramipexole and n-acetylcysteine on global cerebral ischemic reperfusion injury in rats.

Danduga RCSR, Reddy DS, Seshadri SM, Has KSS, Kumar KP.

Iran J Basic Med Sci. 2018 Jun;21(6):569-576. doi: 10.22038/IJBMS.2018.22647.5756.

29.

Measuring Histone Deacetylase Inhibition in the Brain.

Reddy DS, Wu X, Golub VM, Dashwood WM, Dashwood RH.

Curr Protoc Pharmacol. 2018 Jun;81(1):e41. doi: 10.1002/cpph.41. Epub 2018 Jun 7.

30.

Benzodiazepine-refractory status epilepticus, neuroinflammation, and interneuron neurodegeneration after acute organophosphate intoxication.

Kuruba R, Wu X, Reddy DS.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2845-2858. doi: 10.1016/j.bbadis.2018.05.016. Epub 2018 May 23.

31.

Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite.

Das P, Babbar P, Malhotra N, Sharma M, Jachak GR, Gonnade RG, Shanmugam D, Harlos K, Yogavel M, Sharma A, Reddy DS.

J Med Chem. 2018 Jul 12;61(13):5664-5678. doi: 10.1021/acs.jmedchem.8b00565. Epub 2018 Jun 4.

PMID:
29779382
32.

Copper(II)nitrate catalyzed regioselective protection of primary alcohols with 4,4'-dimethoxytrityl and 2,7-dimethyl-9-phenyl xanthen-9-yl groups in nucleosides and carbohydrates.

Penjarla S, Prasad SR, Reddy DS, Banerjee S, Penta S, Sanghvi YS.

Nucleosides Nucleotides Nucleic Acids. 2018;37(4):232-247. doi: 10.1080/15257770.2018.1460480. Epub 2018 May 3.

PMID:
29723125
33.

Removal of lead and fluoride from contaminated water using exhausted coffee grounds based bio-sorbent.

Naga Babu A, Reddy DS, Kumar GS, Ravindhranath K, Krishna Mohan GV.

J Environ Manage. 2018 Jul 15;218:602-612. doi: 10.1016/j.jenvman.2018.04.091. Epub 2018 Apr 30.

PMID:
29715669
34.

A novel mitochondrial orf147 causes cytoplasmic male sterility in pigeonpea by modulating aberrant anther dehiscence.

Bhatnagar-Mathur P, Gupta R, Reddy PS, Reddy BP, Reddy DS, Sameerkumar CV, Saxena RK, Sharma KK.

Plant Mol Biol. 2018 May;97(1-2):131-147. doi: 10.1007/s11103-018-0728-7. Epub 2018 Apr 17.

PMID:
29667000
36.

Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agents: Their DNA cleavage ability and BSA interaction study.

Reddy DS, Kongot M, Netalkar SP, Kurjogi MM, Kumar R, Avecilla F, Kumar A.

Eur J Med Chem. 2018 Apr 25;150:864-875. doi: 10.1016/j.ejmech.2018.03.042. Epub 2018 Mar 20.

PMID:
29597169
37.

Role of β2/3-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis.

Reddy DS, Yoshimura RF, Ramanathan G, Carver C, Johnstone TB, Hogenkamp DJ, Gee KW.

Epilepsy Behav. 2018 May;82:57-63. doi: 10.1016/j.yebeh.2018.02.020. Epub 2018 Mar 26.

PMID:
29587186
38.

GABA-A Receptors Mediate Tonic Inhibition and Neurosteroid Sensitivity in the Brain.

Reddy DS.

Vitam Horm. 2018;107:177-191. doi: 10.1016/bs.vh.2017.12.001. Epub 2018 Feb 9. Review.

PMID:
29544630
39.

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2018 Jan 17;3(1). pii: e00534-17. doi: 10.1128/mSphere.00534-17. eCollection 2018 Jan-Feb. Erratum in: mSphere. 2019 Mar 13;4(2):.

40.

Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.

Chuang SH, Reddy DS.

J Pharmacol Exp Ther. 2018 Feb;364(2):180-197. doi: 10.1124/jpet.117.244673. Epub 2017 Nov 15. Review.

41.

Epigenetic Histone Deacetylation Inhibition Prevents the Development and Persistence of Temporal Lobe Epilepsy.

Reddy SD, Clossen BL, Reddy DS.

J Pharmacol Exp Ther. 2018 Jan;364(1):97-109. doi: 10.1124/jpet.117.244939. Epub 2017 Nov 3.

PMID:
29101217
42.

Atomic force microscopy investigations of fibronectin and α5β1-integrin signaling in neuroplasticity and seizure susceptibility in experimental epilepsy.

Wu X, Muthuchamy M, Reddy DS.

Epilepsy Res. 2017 Dec;138:71-80. doi: 10.1016/j.eplepsyres.2017.10.013. Epub 2017 Oct 24.

PMID:
29096132
43.

Neurocysticercosis as an infectious acquired epilepsy worldwide.

Reddy DS, Volkmer R 2nd.

Seizure. 2017 Nov;52:176-181. doi: 10.1016/j.seizure.2017.10.004. Epub 2017 Oct 7. Review.

44.

Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds.

Ramesh R, Reddy DS.

J Med Chem. 2018 May 10;61(9):3779-3798. doi: 10.1021/acs.jmedchem.7b00718. Epub 2017 Nov 1. Review.

PMID:
29039662
45.

A resurging boom in new drugs for epilepsy and brain disorders.

Younus I, Reddy DS.

Expert Rev Clin Pharmacol. 2018 Jan;11(1):27-45. doi: 10.1080/17512433.2018.1386553. Epub 2017 Oct 23. Review.

PMID:
28956955
46.

Cytological Changes in Normal Oral Mucosa of Individuals with Tobacco Habits: A Cytomorphometric Study.

Palakurthy P, Kulkarni PG, Nandan RK, Rao TM, Reddy DSP, Muddana K.

J Contemp Dent Pract. 2017 Aug 1;18(8):722-727.

PMID:
28816197
47.

Repurposing Ivacaftor for treatment of Staphylococcus aureus infections.

Thakare R, Singh AK, Das S, Vasudevan N, Jachak GR, Reddy DS, Dasgupta A, Chopra S.

Int J Antimicrob Agents. 2017 Sep;50(3):389-392. doi: 10.1016/j.ijantimicag.2017.03.020. Epub 2017 Jul 8.

PMID:
28694231
48.

Access to Fused Tricyclic γ-Butyrolactones, A Natural Product-like Scaffold.

Kalmode HP, Handore KL, Reddy DS.

J Org Chem. 2017 Jul 21;82(14):7614-7620. doi: 10.1021/acs.joc.7b00794. Epub 2017 Jul 10.

PMID:
28636370
49.

Identification of new anti-inflammatory agents based on nitrosporeusine natural products of marine origin.

Philkhana SC, Verma AK, Jachak GR, Hazra B, Basu A, Reddy DS.

Eur J Med Chem. 2017 Jul 28;135:89-109. doi: 10.1016/j.ejmech.2017.04.015. Epub 2017 Apr 13.

PMID:
28433779
50.

Response to: 'Birth control in epilepsy: we need to know more'.

Reddy DS.

Expert Rev Neurother. 2017 Jun;17(6):523. doi: 10.1080/14737175.2017.1314183. Epub 2017 Apr 10. No abstract available.

PMID:
28359202

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