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Items: 13


Data Sharing from Clinical Trials - A Research Funder's Perspective.

Kiley R, Peatfield T, Hansen J, Reddington F.

N Engl J Med. 2017 Nov 16;377(20):1990-1992. doi: 10.1056/NEJMsb1708278. No abstract available.


Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.

Veerapen N, Reddington F, Salio M, Cerundolo V, Besra GS.

Bioorg Med Chem. 2011 Jan 1;19(1):221-8. doi: 10.1016/j.bmc.2010.11.032. Epub 2010 Nov 19.


Synthesis and biological activity of alpha-L-fucosyl ceramides, analogues of the potent agonist, alpha-D-galactosyl ceramide KRN7000.

Veerapen N, Reddington F, Bricard G, Porcelli SA, Besra GS.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3223-6. doi: 10.1016/j.bmcl.2010.04.079. Epub 2010 Apr 22.


Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin.

Venkataswamy MM, Baena A, Goldberg MF, Bricard G, Im JS, Chan J, Reddington F, Besra GS, Jacobs WR Jr, Porcelli SA.

J Immunol. 2009 Aug 1;183(3):1644-56. doi: 10.4049/jimmunol.0900858.


The UK National Cancer Research Institute (NCRI) Informatics Initiative: promoting partnership in cancer research.

Reddington F, Ajose-Adeogun A, Clark R.

Hum Mutat. 2007 Dec;28(12):1151-5.


The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.

McCarthy C, Shepherd D, Fleire S, Stronge VS, Koch M, Illarionov PA, Bossi G, Salio M, Denkberg G, Reddington F, Tarlton A, Reddy BG, Schmidt RR, Reiter Y, Griffiths GM, van der Merwe PA, Besra GS, Jones EY, Batista FD, Cerundolo V.

J Exp Med. 2007 May 14;204(5):1131-44. Epub 2007 May 7.


Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules.

Chen X, Wang X, Keaton JM, Reddington F, Illarionov PA, Besra GS, Gumperz JE.

J Immunol. 2007 May 15;178(10):6181-90.


Incentivizing standards development and adoption.

Reddington F, Wilkinson JM, Clark R, Begent RH.

Nat Biotechnol. 2007 Apr;25(4):391-2. No abstract available.


NKT cells direct monocytes into a DC differentiation pathway.

Hegde S, Chen X, Keaton JM, Reddington F, Besra GS, Gumperz JE.

J Leukoc Biol. 2007 May;81(5):1224-35. Epub 2007 Feb 20.


Cancer informatics in the U.K.: the NCRI informatics initiative.

Reddington F, Wilkinson JM, Clark R, Parkinson H, Kerr P, Begent R.

Cancer Inform. 2007 Feb 26;2:389-94.


The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d.

Van Rhijn I, Koets AP, Im JS, Piebes D, Reddington F, Besra GS, Porcelli SA, van Eden W, Rutten VP.

J Immunol. 2006 Apr 15;176(8):4888-93.


Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors.

Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE.

J Immunol. 2006 Mar 15;176(6):3625-34.


NCRI informatics initiative.

Begent RH, Kerr P, Parkinson H, Reddington F, Wilkinson JM.

Nat Biotechnol. 2005 Oct;23(10):1212. No abstract available.


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