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The Impact of Persistent Leukoencephalopathy on Brain White Matter Microstructure in Long-Term Survivors of Acute Lymphoblastic Leukemia Treated with Chemotherapy Only.

Sabin ND, Cheung YT, Reddick WE, Bhojwani D, Liu W, Glass JO, Brinkman TM, Hwang SN, Srivastava D, Pui CH, Robison LL, Hudson MM, Krull KR.

AJNR Am J Neuroradiol. 2018 Oct;39(10):1919-1925. doi: 10.3174/ajnr.A5791. Epub 2018 Sep 13.


Brain Network Connectivity and Executive Function in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia.

Kesler SR, Ogg R, Reddick WE, Phillips N, Scoggins M, Glass JO, Cheung YT, Pui CH, Robison LL, Hudson MM, Krull KR.

Brain Connect. 2018 Aug;8(6):333-342. doi: 10.1089/brain.2017.0574.


Association of Cerebrospinal Fluid Biomarkers of Central Nervous System Injury With Neurocognitive and Brain Imaging Outcomes in Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia.

Cheung YT, Khan RB, Liu W, Brinkman TM, Edelmann MN, Reddick WE, Pei D, Panoskaltsis-Mortari A, Srivastava D, Cheng C, Robison LL, Hudson MM, Pui CH, Krull KR.

JAMA Oncol. 2018 Jul 12;4(7):e180089. doi: 10.1001/jamaoncol.2018.0089. Epub 2018 Jul 12.


Parent perspectives and preferences for strategies regarding nonsedated MRI scans in a pediatric oncology population.

Walker B, Conklin HM, Anghelescu DL, Hall LP, Reddick WE, Ogg R, Jacola LM.

Support Care Cancer. 2018 Jun;26(6):1815-1824. doi: 10.1007/s00520-017-4009-9. Epub 2017 Dec 19.


The challenge of mapping the human connectome based on diffusion tractography.

Maier-Hein KH, Neher PF, Houde JC, Côté MA, Garyfallidis E, Zhong J, Chamberland M, Yeh FC, Lin YC, Ji Q, Reddick WE, Glass JO, Chen DQ, Feng Y, Gao C, Wu Y, Ma J, Renjie H, Li Q, Westin CF, Deslauriers-Gauthier S, González JOO, Paquette M, St-Jean S, Girard G, Rheault F, Sidhu J, Tax CMW, Guo F, Mesri HY, Dávid S, Froeling M, Heemskerk AM, Leemans A, Boré A, Pinsard B, Bedetti C, Desrosiers M, Brambati S, Doyon J, Sarica A, Vasta R, Cerasa A, Quattrone A, Yeatman J, Khan AR, Hodges W, Alexander S, Romascano D, Barakovic M, Auría A, Esteban O, Lemkaddem A, Thiran JP, Cetingul HE, Odry BL, Mailhe B, Nadar MS, Pizzagalli F, Prasad G, Villalon-Reina JE, Galvis J, Thompson PM, Requejo FS, Laguna PL, Lacerda LM, Barrett R, Dell'Acqua F, Catani M, Petit L, Caruyer E, Daducci A, Dyrby TB, Holland-Letz T, Hilgetag CC, Stieltjes B, Descoteaux M.

Nat Commun. 2017 Nov 7;8(1):1349. doi: 10.1038/s41467-017-01285-x.


A 3D model-based simulation of demyelination to understand its effects on diffusion tensor imaging.

Salan T, Jacobs EL, Reddick WE.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:3525-3528. doi: 10.1109/EMBC.2017.8037617.


18F-FDG Uptake During Early Adjuvant Chemotherapy Predicts Histologic Response in Pediatric and Young Adult Patients with Osteosarcoma.

Davis JC, Daw NC, Navid F, Billups CA, Wu J, Bahrami A, Jenkins JJ, Snyder SE, Reddick WE, Santana VM, McCarville MB, Guo J, Shulkin BL.

J Nucl Med. 2018 Jan;59(1):25-30. doi: 10.2967/jnumed.117.190595. Epub 2017 Jun 13.


Disrupted development and integrity of frontal white matter in patients treated for pediatric medulloblastoma.

Glass JO, Ogg RJ, Hyun JW, Harreld JH, Schreiber JE, Palmer SL, Li Y, Gajjar AJ, Reddick WE.

Neuro Oncol. 2017 Oct 1;19(10):1408-1418. doi: 10.1093/neuonc/nox062.


Measurable Supratentorial White Matter Volume Changes in Patients with Diffuse Intrinsic Pontine Glioma Treated with an Anti-Vascular Endothelial Growth Factor Agent, Steroids, and Radiation.

Svolos P, Reddick WE, Edwards A, Sykes A, Li Y, Glass JO, Patay Z.

AJNR Am J Neuroradiol. 2017 Jun;38(6):1235-1241. doi: 10.3174/ajnr.A5159. Epub 2017 Apr 20.


Neurocognitive outcomes among children who experienced seizures during treatment for acute lymphoblastic leukemia.

Nassar SL, Conklin HM, Zhou Y, Ashford JM, Reddick WE, Glass JO, Laningham FH, Jeha S, Cheng C, Pui CH.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26436. Epub 2017 Jan 28.


Leukoencephalopathy and long-term neurobehavioural, neurocognitive, and brain imaging outcomes in survivors of childhood acute lymphoblastic leukaemia treated with chemotherapy: a longitudinal analysis.

Cheung YT, Sabin ND, Reddick WE, Bhojwani D, Liu W, Brinkman TM, Glass JO, Hwang SN, Srivastava D, Pui CH, Robison LL, Hudson MM, Krull KR.

Lancet Haematol. 2016 Oct;3(10):e456-e466. doi: 10.1016/S2352-3026(16)30110-7. Epub 2016 Sep 14.


Reply to S. Kaur et al.

Jacola LM, Krull KR, Pui CH, Pei D, Cheng C, Reddick WE, Conklin HM.

J Clin Oncol. 2016 Oct 20;34(30):3708-3709. doi: 10.1200/JCO.2016.68.7780. No abstract available.


Fast frequency-sweep spectroscopic imaging with an ultra-low flip angle.

Guo J, Patay Z, Reddick WE.

Sci Rep. 2016 Jul 21;6:30066. doi: 10.1038/srep30066.


Chemotherapy Pharmacodynamics and Neuroimaging and Neurocognitive Outcomes in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia.

Krull KR, Cheung YT, Liu W, Fellah S, Reddick WE, Brinkman TM, Kimberg C, Ogg R, Srivastava D, Pui CH, Robison LL, Hudson MM.

J Clin Oncol. 2016 Aug 1;34(22):2644-53. doi: 10.1200/JCO.2015.65.4574. Epub 2016 Jun 6.


MRI Evaluation of Non-Necrotic T2-Hyperintense Foci in Pediatric Diffuse Intrinsic Pontine Glioma.

Clerk-Lamalice O, Reddick WE, Li X, Li Y, Edwards A, Glass JO, Patay Z.

AJNR Am J Neuroradiol. 2016 Oct;37(10):1930-1937. doi: 10.3174/ajnr.A4814. Epub 2016 May 19.


Longitudinal Assessment of Neurocognitive Outcomes in Survivors of Childhood Acute Lymphoblastic Leukemia Treated on a Contemporary Chemotherapy Protocol.

Jacola LM, Krull KR, Pui CH, Pei D, Cheng C, Reddick WE, Conklin HM.

J Clin Oncol. 2016 Apr 10;34(11):1239-47. doi: 10.1200/JCO.2015.64.3205. Epub 2016 Feb 8.


Assessing vascular effects of adding bevacizumab to neoadjuvant chemotherapy in osteosarcoma using DCE-MRI.

Guo J, Glass JO, McCarville MB, Shulkin BL, Daryani VM, Stewart CF, Wu J, Mao S, Dwek JR, Fayad LM, Madewell JE, Navid F, Daw NC, Reddick WE.

Br J Cancer. 2015 Nov 3;113(9):1282-8. doi: 10.1038/bjc.2015.351. Epub 2015 Oct 13.


Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections.

Wright KD, Panetta JC, Onar-Thomas A, Reddick WE, Patay Z, Qaddoumi I, Broniscer A, Robinson G, Boop FA, Klimo P Jr, Ward D, Gajjar A, Stewart CF.

Cancer Chemother Pharmacol. 2015 Jan;75(1):27-35. doi: 10.1007/s00280-014-2614-6. Epub 2014 Oct 24.


Diffusion tensor imaging and neurocognition in survivors of childhood acute lymphoblastic leukaemia.

Edelmann MN, Krull KR, Liu W, Glass JO, Ji Q, Ogg RJ, Sabin ND, Srivastava DK, Robison LL, Hudson MM, Reddick WE.

Brain. 2014 Nov;137(Pt 11):2973-83. doi: 10.1093/brain/awu230. Epub 2014 Aug 13.


Comparing segmented ASL perfusion of vascular territories using manual versus semiautomated techniques in children with sickle cell anemia.

Helton KJ, Glass JO, Reddick WE, Paydar A, Zandieh AR, Dave R, Smeltzer MP, Wu S, Hankins J, Aygun B, Ogg RJ.

J Magn Reson Imaging. 2015 Feb;41(2):439-46. doi: 10.1002/jmri.24559. Epub 2014 Jan 8.


The relationship between working memory and cerebral white matter volume in survivors of childhood brain tumors treated with conformal radiation therapy.

Jacola LM, Ashford JM, Reddick WE, Glass JO, Ogg RJ, Merchant TE, Conklin HM.

J Neurooncol. 2014 Aug;119(1):197-205. doi: 10.1007/s11060-014-1476-4. Epub 2014 May 22.


Elevated cerebral blood volume contributes to increased FLAIR signal in the cerebral sulci of propofol-sedated children.

Harreld JH, Sabin ND, Rossi MG, Awwad R, Reddick WE, Yuan Y, Glass JO, Ji Q, Gajjar A, Patay Z.

AJNR Am J Neuroradiol. 2014 Aug;35(8):1574-9. doi: 10.3174/ajnr.A3911. Epub 2014 Apr 3.


Comment on Smithson et al.'s review of stimulant medication usage to improve neurocognitive and learning outcomes in childhood brain tumour survivors.

Conklin HM, Reddick WE, Khan RB.

Eur J Cancer. 2014 May;50(8):1566-8. doi: 10.1016/j.ejca.2014.01.032. Epub 2014 Mar 24. No abstract available.


"Occult" post-contrast signal enhancement in pediatric diffuse intrinsic pontine glioma is the MRI marker of angiogenesis?

Conway AE, Reddick WE, Li Y, Yuan Y, Glass JO, Baker JN, Kun LE, Broniscer A, Patay Z.

Neuroradiology. 2014 May;56(5):405-12. doi: 10.1007/s00234-014-1348-9. Epub 2014 Mar 14.


Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia.

Bhojwani D, Sabin ND, Pei D, Yang JJ, Khan RB, Panetta JC, Krull KR, Inaba H, Rubnitz JE, Metzger ML, Howard SC, Ribeiro RC, Cheng C, Reddick WE, Jeha S, Sandlund JT, Evans WE, Pui CH, Relling MV.

J Clin Oncol. 2014 Mar 20;32(9):949-59. doi: 10.1200/JCO.2013.53.0808. Epub 2014 Feb 18.


Incidental detection of late subsequent intracranial neoplasms with magnetic resonance imaging among adult survivors of childhood cancer.

Sabin ND, Santucci AK, Klimo P Jr, Hudson MM, Srivastava D, Zhang N, Kun LE, Krasin MJ, Pui CH, Patay Z, Reddick WE, Ogg RJ, Hillenbrand CM, Robison LL, Krull KR, Armstrong GT.

J Cancer Surviv. 2014 Sep;8(3):329-35. doi: 10.1007/s11764-014-0344-8. Epub 2014 Feb 2.


Prognostic factors that increase the risk for reduced white matter volumes and deficits in attention and learning for survivors of childhood cancers.

Reddick WE, Taghipour DJ, Glass JO, Ashford J, Xiong X, Wu S, Bonner M, Khan RB, Conklin HM.

Pediatr Blood Cancer. 2014 Jun;61(6):1074-9. doi: 10.1002/pbc.24947. Epub 2014 Jan 25.


Cerebral glucose metabolism on positron emission tomography of children.

Shan ZY, Leiker AJ, Onar-Thomas A, Li Y, Feng T, Reddick WE, Reutens DC, Shulkin BL.

Hum Brain Mapp. 2014 May;35(5):2297-309. doi: 10.1002/hbm.22328. Epub 2013 Jul 29.


The effects of propofol on cerebral perfusion MRI in children.

Harreld JH, Helton KJ, Kaddoum RN, Reddick WE, Li Y, Glass JO, Sansgiri R, Ji Q, Feng T, Parish ME, Gajjar A, Patay Z.

Neuroradiology. 2013 Aug;55(8):1049-1056. doi: 10.1007/s00234-013-1187-0. Epub 2013 May 15.


Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia.

Krull KR, Bhojwani D, Conklin HM, Pei D, Cheng C, Reddick WE, Sandlund JT, Pui CH.

J Clin Oncol. 2013 Jun 10;31(17):2182-8. doi: 10.1200/JCO.2012.46.7944. Epub 2013 May 6.


Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy.

Armstrong GT, Reddick WE, Petersen RC, Santucci A, Zhang N, Srivastava D, Ogg RJ, Hillenbrand CM, Sabin N, Krasin MJ, Kun L, Pui CH, Hudson MM, Robison LL, Krull KR.

J Natl Cancer Inst. 2013 Jun 19;105(12):899-907. doi: 10.1093/jnci/djt089. Epub 2013 Apr 12.


Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumors.

Navid F, Baker SD, McCarville MB, Stewart CF, Billups CA, Wu J, Davidoff AM, Spunt SL, Furman WL, McGregor LM, Hu S, Panetta JC, Turner D, Fofana D, Reddick WE, Leung W, Santana VM.

Clin Cancer Res. 2013 Jan 1;19(1):236-46. doi: 10.1158/1078-0432.CCR-12-1897. Epub 2012 Nov 8. Erratum in: Clin Cancer Res. 2013 Apr 1;19(7):1914.


Multi-slice myelin water imaging for practical clinical applications at 3.0 T.

Guo J, Ji Q, Reddick WE.

Magn Reson Med. 2013 Sep;70(3):813-22. doi: 10.1002/mrm.24527. Epub 2012 Nov 6.


Cerebral white matter integrity and executive function in adult survivors of childhood medulloblastoma.

Brinkman TM, Reddick WE, Luxton J, Glass JO, Sabin ND, Srivastava DK, Robison LL, Hudson MM, Krull KR.

Neuro Oncol. 2012 Sep;14 Suppl 4:iv25-36. doi: 10.1093/neuonc/nos214.


Neurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma.

Krull KR, Sabin ND, Reddick WE, Zhu L, Armstrong GT, Green DM, Arevalo AR, Krasin MJ, Srivastava DK, Robison LL, Hudson MM.

J Clin Oncol. 2012 Oct 10;30(29):3618-24. doi: 10.1200/JCO.2012.42.6841. Epub 2012 Sep 4.


Cognitive outcomes following contemporary treatment without cranial irradiation for childhood acute lymphoblastic leukemia.

Conklin HM, Krull KR, Reddick WE, Pei D, Cheng C, Pui CH.

J Natl Cancer Inst. 2012 Sep 19;104(18):1386-95. Epub 2012 Aug 27.


White matter integrity is associated with cognitive processing in patients treated for a posterior fossa brain tumor.

Palmer SL, Glass JO, Li Y, Ogg R, Qaddoumi I, Armstrong GT, Wright K, Wetmore C, Broniscer A, Gajjar A, Reddick WE.

Neuro Oncol. 2012 Sep;14(9):1185-93. doi: 10.1093/neuonc/nos154. Epub 2012 Aug 16.


Working memory performance among childhood brain tumor survivors.

Conklin HM, Ashford JM, Howarth RA, Merchant TE, Ogg RJ, Santana VM, Reddick WE, Wu S, Xiong X.

J Int Neuropsychol Soc. 2012 Nov;18(6):996-1005. doi: 10.1017/S1355617712000793. Epub 2012 Jun 13.


Dynamic contrast-enhanced magnetic resonance imaging as a prognostic factor in predicting event-free and overall survival in pediatric patients with osteosarcoma.

Guo J, Reddick WE, Glass JO, Ji Q, Billups CA, Wu J, Hoffer FA, Kaste SC, Jenkins JJ, Ortega Flores XC, Quintana J, Villarroel M, Daw NC.

Cancer. 2012 Aug 1;118(15):3776-85. doi: 10.1002/cncr.26701. Epub 2011 Dec 16.


Impact of acute lymphoblastic leukemia therapy on attention and working memory in children.

Reddick WE, Conklin HM.

Expert Rev Hematol. 2010 Dec;3(6):655-9. doi: 10.1586/ehm.10.65. No abstract available.


Quantitative diffusion-weighted and dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging analysis of T2 hypointense lesion components in pediatric diffuse intrinsic pontine glioma.

Löbel U, Sedlacik J, Reddick WE, Kocak M, Ji Q, Broniscer A, Hillenbrand CM, Patay Z.

AJNR Am J Neuroradiol. 2011 Feb;32(2):315-22. doi: 10.3174/ajnr.A2277. Epub 2010 Nov 18.


Long-term efficacy of methylphenidate in enhancing attention regulation, social skills, and academic abilities of childhood cancer survivors.

Conklin HM, Reddick WE, Ashford J, Ogg S, Howard SC, Morris EB, Brown R, Bonner M, Christensen R, Wu S, Xiong X, Khan RB.

J Clin Oncol. 2010 Oct 10;28(29):4465-72. doi: 10.1200/JCO.2010.28.4026. Epub 2010 Sep 13. Erratum in: J Clin Oncol. 2010 Dec 20;28(36):5350.


Attention and working memory abilities in children treated for acute lymphoblastic leukemia.

Ashford J, Schoffstall C, Reddick WE, Leone C, Laningham FH, Glass JO, Pei D, Cheng C, Pui CH, Conklin HM.

Cancer. 2010 Oct 1;116(19):4638-45. doi: 10.1002/cncr.25343.


Regional white matter anisotropy and reading ability in patients treated for pediatric embryonal tumors.

Palmer SL, Reddick WE, Glass JO, Ogg R, Patay Z, Wallace D, Gajjar A.

Brain Imaging Behav. 2010 Jun;4(2):132-40. doi: 10.1007/s11682-010-9092-1.


Retrospective evaluation of PET-MRI registration algorithms.

Shan ZY, Mateja SJ, Reddick WE, Glass JO, Shulkin BL.

J Digit Imaging. 2011 Jun;24(3):485-93. doi: 10.1007/s10278-010-9300-y.


Cerebellocerebral diaschisis is the likely mechanism of postsurgical posterior fossa syndrome in pediatric patients with midline cerebellar tumors.

Miller NG, Reddick WE, Kocak M, Glass JO, Löbel U, Morris B, Gajjar A, Patay Z.

AJNR Am J Neuroradiol. 2010 Feb;31(2):288-94. doi: 10.3174/ajnr.A1821. Epub 2009 Oct 1.


Voxel-based analysis of T2 hyperintensities in white matter during treatment of childhood leukemia.

Reddick WE, Glass JO, Johnson DP, Laningham FH, Pui CH.

AJNR Am J Neuroradiol. 2009 Nov;30(10):1947-54. doi: 10.3174/ajnr.A1733. Epub 2009 Jul 30.


Dynamic contrast-enhanced magnetic resonance imaging parameters independent of baseline T10 values.

Guo JY, Reddick WE, Rosen MA, Song HK.

Magn Reson Imaging. 2009 Nov;27(9):1208-15. doi: 10.1016/j.mri.2009.05.015. Epub 2009 Jun 25.


DCE-MRI pixel-by-pixel quantitative curve pattern analysis and its application to osteosarcoma.

Guo JY, Reddick WE.

J Magn Reson Imaging. 2009 Jul;30(1):177-84. doi: 10.1002/jmri.21785.


Predicting methylphenidate response in long-term survivors of childhood cancer: a randomized, double-blind, placebo-controlled, crossover trial.

Conklin HM, Helton S, Ashford J, Mulhern RK, Reddick WE, Brown R, Bonner M, Jasper BW, Wu S, Xiong X, Khan RB.

J Pediatr Psychol. 2010 Mar;35(2):144-55. doi: 10.1093/jpepsy/jsp044. Epub 2009 May 22.

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