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Items: 1 to 50 of 130

1.

The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner.

Srikantan S, Deng Y, Cheng ZM, Luo A, Qin Y, Gao Q, Sande-Docor GM, Tao S, Zhang X, Harper N, Shannon CE, Fourcaudot M, Li Z, Kasinath BS, Harrison S, Ahuja S, Reddick RL, Dong LQ, Abdul-Ghani M, Norton L, Aguiar RCT, Dahia PLM.

Nat Commun. 2019 Oct 17;10(1):4720. doi: 10.1038/s41467-019-12661-0.

PMID:
31624249
2.

Receptor tyrosine kinase recepteur d'origine nantais as predictive marker for aggressive prostate cancer in African Americans.

Bedolla RG, Shah DP, Huang SB, Reddick RL, Ghosh R, Kumar AP.

Mol Carcinog. 2019 Jun;58(6):854-861. doi: 10.1002/mc.23002. Epub 2019 Mar 11.

PMID:
30859654
3.

Endothelial cell-specific overexpression of endothelial nitric oxide synthase in Ins2Akita mice exacerbates diabetic nephropathy.

Natarajan M, Habib SL, Reddick RL, Delma CR, Manickam K, Prihoda TJ, Werner SL, Mohan S.

J Diabetes Complications. 2019 Jan;33(1):23-32. doi: 10.1016/j.jdiacomp.2018.10.003. Epub 2018 Oct 13.

PMID:
30424931
4.

NFκB Regulates Muscle Development and Mitochondrial Function.

Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N.

J Gerontol A Biol Sci Med Sci. 2018 Nov 13. doi: 10.1093/gerona/gly262. [Epub ahead of print]

PMID:
30423026
5.

Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation.

Hussain SS, Huang SB, Bedolla RG, Rivas P, Basler JW, Swanson GP, Hui-Ming Huang T, Narayanasamy G, Papanikolaou N, Miyamoto H, Yeh IT, Reddick RL, Pollock BH, Ghosh R, Kumar AP.

Cancer Lett. 2018 Oct 1;433:232-241. doi: 10.1016/j.canlet.2018.07.009. Epub 2018 Jul 9.

PMID:
30003927
6.

A Unique Case of Metastatic, Functional, Hereditary Paraganglioma Associated With an SDHC Germline Mutation.

Ong RKS, Flores SK, Reddick RL, Dahia PLM, Shawa H.

J Clin Endocrinol Metab. 2018 Aug 1;103(8):2802-2806. doi: 10.1210/jc.2017-01302.

PMID:
29878124
7.

Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells.

Zanotto-Filho A, Rajamanickam S, Loranc E, Masamsetti VP, Gorthi A, Romero JC, Tonapi S, Gonçalves RM, Reddick RL, Benavides R, Kuhn J, Chen Y, Bishop AJR.

Cancer Lett. 2018 Jul 1;425:101-115. doi: 10.1016/j.canlet.2018.03.037. Epub 2018 Mar 30.

8.

Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.

Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ.

Oncotarget. 2017 Aug 21;8(34):57905. doi: 10.18632/oncotarget.20370. eCollection 2017 Aug 22.

9.

A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.

Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ.

Oncotarget. 2016 Dec 27;7(52):86087-86102. doi: 10.18632/oncotarget.13343. Erratum in: Oncotarget. 2017 Aug 21;8(34):57905.

10.

Infectious Diseases of the Heart: Pathophysiology, Clinical and Imaging Overview.

Murillo H, Restrepo CS, Marmol-Velez JA, Vargas D, Ocazionez D, Martinez-Jimenez S, Reddick RL, Baxi AJ.

Radiographics. 2016 Jul-Aug;36(4):963-83. doi: 10.1148/rg.2016150225. Review.

PMID:
27399236
11.

Recurrent Mutations of Chromatin-Remodeling Genes and Kinase Receptors in Pheochromocytomas and Paragangliomas.

Toledo RA, Qin Y, Cheng ZM, Gao Q, Iwata S, Silva GM, Prasad ML, Ocal IT, Rao S, Aronin N, Barontini M, Bruder J, Reddick RL, Chen Y, Aguiar RC, Dahia PL.

Clin Cancer Res. 2016 May 1;22(9):2301-10. doi: 10.1158/1078-0432.CCR-15-1841. Epub 2015 Dec 23.

12.

DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase Status.

Herzig MC, Zavadil JA, Street K, Hildreth K, Drinkwater NR, Reddick T, Herbert DC, Hanes MA, McMahan CA, Reddick RL, Walter CA.

Cancer Prev Res (Phila). 2016 Mar;9(3):245-52. doi: 10.1158/1940-6207.CAPR-15-0251. Epub 2015 Dec 14.

13.

Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice.

Krishnan M, Janardhanan P, Roman L, Reddick RL, Natarajan M, van Haperen R, Habib SL, de Crom R, Mohan S.

Lab Invest. 2015 Oct;95(10):1092-104. doi: 10.1038/labinvest.2015.96. Epub 2015 Jul 27.

14.

Hematopoietic knockdown of PPARδ reduces atherosclerosis in LDLR-/- mice.

Li G, Chen C, Laing SD, Ballard C, Biju KC, Reddick RL, Clark RA, Li S.

Gene Ther. 2016 Jan;23(1):78-85. doi: 10.1038/gt.2015.78. Epub 2015 Aug 23.

15.

Sycosis Vaccinatum, a Type of Vaccinia Folliculitis.

Braswell MA, Morrissey MW, Ritchie SA, Reddick RL, Kobayashi TT.

JAMA Dermatol. 2015 Jul;151(7):799-801. doi: 10.1001/jamadermatol.2015.0380. No abstract available.

PMID:
25902195
16.

NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.

Thapa D, Meng P, Bedolla RG, Reddick RL, Kumar AP, Ghosh R.

Cancer Res. 2014 Oct 1;74(19):5644-55. doi: 10.1158/0008-5472.CAN-14-0562. Epub 2014 Aug 14.

17.

Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum.

Zhang H, Zhou Z, Chen J, Wu G, Yang Z, Zhou Z, Baseman J, Zhang J, Reddick RL, Zhong G.

Infect Immun. 2014 Jul;82(7):2688-96. doi: 10.1128/IAI.00055-14. Epub 2014 Apr 7.

18.

Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function.

Muscogiuri G, Salmon AB, Aguayo-Mazzucato C, Li M, Balas B, Guardado-Mendoza R, Giaccari A, Reddick RL, Reyna SM, Weir G, Defronzo RA, Van Remmen H, Musi N.

Diabetes. 2013 Dec;62(12):4201-7. doi: 10.2337/db13-0314. Epub 2013 Sep 5.

19.

Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.

Li G, Rivas P, Bedolla R, Thapa D, Reddick RL, Ghosh R, Kumar AP.

Cancer Prev Res (Phila). 2013 Jan;6(1):27-39. doi: 10.1158/1940-6207.CAPR-12-0349. Epub 2012 Dec 17.

20.

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan.

Chen PL, Chen CF, Chen Y, Guo XE, Huang CK, Shew JY, Reddick RL, Wallace DC, Lee WH.

Oncogene. 2013 Feb 28;32(9):1193-201. doi: 10.1038/onc.2012.120. Epub 2012 May 7.

21.

Human O6 -methylguanine-DNA methyltransferase containing C145A does not prevent hepatocellular carcinoma in C3HeB/FeJ transgenic mice.

Herzig MC, Hildreth K, Huamani J, Perez M, Goins BA, McMahan CA, Reddick RL, Walter CA.

Mol Carcinog. 2013 Apr;52(4):275-85. doi: 10.1002/mc.21855. Epub 2011 Dec 27.

PMID:
22213062
22.

Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome.

Martinez HG, Quinones MP, Jimenez F, Estrada CA, Clark K, Muscogiuri G, Sorice G, Musi N, Reddick RL, Ahuja SS.

Diabetologia. 2011 Oct;54(10):2660-8. doi: 10.1007/s00125-011-2248-8. Epub 2011 Jul 21.

23.

Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.

Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8779-84. doi: 10.1073/pnas.1106344108. Epub 2011 May 9.

24.

Macrophage LXRα gene therapy ameliorates atherosclerosis as well as hypertriglyceridemia in LDLR(-/-) mice.

Li G, Biju KC, Xu X, Zhou Q, Chen C, Valente AJ, He W, Reddick RL, Freeman GL, Ahuja SS, Clark RA, Li S.

Gene Ther. 2011 Aug;18(8):835-41. doi: 10.1038/gt.2011.29. Epub 2011 Mar 10.

PMID:
21390069
25.

Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus.

Matthews MR, Wang RC, Reddick RL, Saldivar VA, Browning JC.

J Cutan Pathol. 2011 May;38(5):420-31. doi: 10.1111/j.1600-0560.2010.01664.x. Epub 2011 Jan 19. Review.

26.

Malignancy arising in seminal vesicles in the transgenic adenocarcinoma of mouse prostate (TRAMP) model.

Yeh IT, Reddick RL, Kumar AP.

Prostate. 2009 May 15;69(7):755-60. doi: 10.1002/pros.20924.

PMID:
19170049
27.

Diabetic eNOS knockout mice develop distinct macro- and microvascular complications.

Mohan S, Reddick RL, Musi N, Horn DA, Yan B, Prihoda TJ, Natarajan M, Abboud-Werner SL.

Lab Invest. 2008 May;88(5):515-28. doi: 10.1038/labinvest.2008.23. Epub 2008 Apr 7.

28.

Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt.

Quinones MP, Kalkonde Y, Estrada CA, Jimenez F, Ramirez R, Mahimainathan L, Mummidi S, Choudhury GG, Martinez H, Adams L, Mack M, Reddick RL, Maffi S, Haralambous S, Probert L, Ahuja SK, Ahuja SS.

Mol Cell Neurosci. 2008 Jan;37(1):96-109. Epub 2007 Sep 14.

29.

Intra-organ variation in age-related mutation accumulation in the mouse.

Busuttil RA, Garcia AM, Reddick RL, Dollé ME, Calder RB, Nelson JF, Vijg J.

PLoS One. 2007 Sep 12;2(9):e876.

30.

CC chemokine receptor 5 influences late-stage atherosclerosis.

Quinones MP, Martinez HG, Jimenez F, Estrada CA, Dudley M, Willmon O, Kulkarni H, Reddick RL, Fernandes G, Kuziel WA, Ahuja SK, Ahuja SS.

Atherosclerosis. 2007 Nov;195(1):e92-103. Epub 2007 Apr 26.

PMID:
17466311
31.

Development of a synthetic promoter for macrophage gene therapy.

He W, Qiang M, Ma W, Valente AJ, Quinones MP, Wang W, Reddick RL, Xiao Q, Ahuja SS, Clark RA, Freeman GL, Li S.

Hum Gene Ther. 2006 Sep;17(9):949-59.

PMID:
16972763
32.

CC chemokine receptor (CCR)-2 prevents arthritis development following infection by Mycobacterium avium.

Quinones MP, Jimenez F, Martinez H, Estrada CA, Willmon O, Dudley M, Kuziel WA, Melby PC, Reddick RL, Ahuja SK, Ahuja SS.

J Mol Med (Berl). 2006 Jun;84(6):503-12. Epub 2006 Mar 7.

PMID:
16520943
33.

Prevention of metastases with a Mage-b DNA vaccine in a mouse breast tumor model: potential for breast cancer therapy.

Sypniewska RK, Hoflack L, Tarango M, Gauntt S, Leal BZ, Reddick RL, Gravekamp C.

Breast Cancer Res Treat. 2005 May;91(1):19-28.

PMID:
15868428
34.

Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis.

Quinones MP, Ahuja SK, Jimenez F, Schaefer J, Garavito E, Rao A, Chenaux G, Reddick RL, Kuziel WA, Ahuja SS.

J Clin Invest. 2004 Mar;113(6):856-66.

35.

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.

Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, Fraire AE, Gabrielson EW, Gunning WT, Haines DC, Kaufman MH, Linnoila RI, Maronpot RR, Rabson AS, Reddick RL, Rehm S, Rozengurt N, Schuller HM, Shmidt EN, Travis WD, Ward JM, Jacks T.

Cancer Res. 2004 Apr 1;64(7):2307-16. Review. Erratum in: Cancer Res. 2004 May 15;64(10):3725.

36.

CC chemokine receptor 2 expression in donor cells serves an essential role in graft-versus-host-disease.

Rao AR, Quinones MP, Garavito E, Kalkonde Y, Jimenez F, Gibbons C, Perez J, Melby P, Kuziel W, Reddick RL, Ahuja SK, Ahuja SS.

J Immunol. 2003 Nov 1;171(9):4875-85.

37.

CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice.

Kuziel WA, Dawson TC, Quinones M, Garavito E, Chenaux G, Ahuja SS, Reddick RL, Maeda N.

Atherosclerosis. 2003 Mar;167(1):25-32.

PMID:
12618265
38.

Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E.

Wu JH, Hagaman J, Kim S, Reddick RL, Maeda N.

Arterioscler Thromb Vasc Biol. 2002 Mar 1;22(3):469-75.

PMID:
11884292
39.

Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice.

Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N.

J Clin Invest. 2001 Feb;107(3):333-40.

42.

Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment.

Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N.

J Clin Invest. 2000 Feb;105(4):451-8.

43.
44.

Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection.

Ahuja SS, Reddick RL, Sato N, Montalbo E, Kostecki V, Zhao W, Dolan MJ, Melby PC, Ahuja SK.

J Immunol. 1999 Oct 1;163(7):3890-7.

45.
46.

Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice.

Reddick RL, Zhang SH, Maeda N.

Atherosclerosis. 1998 Oct;140(2):297-305.

PMID:
9862272
47.

von Willebrand factor does not influence atherogenesis in arteries subjected to altered shear stress.

Nichols TC, Bellinger DA, Reddick RL, Koch GG, Sigman JL, Erickson G, du Laney T, Johnson T, Read MS, Griggs TR.

Arterioscler Thromb Vasc Biol. 1998 Feb;18(2):323-30. Review.

PMID:
9485000
48.

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A.

Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N.

Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14730-5.

49.

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis.

Sullivan PM, Mezdour H, Aratani Y, Knouff C, Najib J, Reddick RL, Quarfordt SH, Maeda N.

J Biol Chem. 1997 Jul 18;272(29):17972-80.

50.

Angiotensin-converting enzyme gene and atherosclerosis.

Krege JH, Moyer JS, Langenbach LL, Peng L, Zhang SH, Maeda N, Reddick RL, Smithies O.

Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1245-50.

PMID:
9261253

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