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Items: 1 to 50 of 157

1.

'Checks and balances' in cytomegalovirus-host cohabitation.

Reddehase MJ.

Med Microbiol Immunol. 2019 Aug;208(3-4):259-261. doi: 10.1007/s00430-019-00618-5. Epub 2019 May 25. No abstract available.

PMID:
31129788
2.

Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease.

Reddehase MJ.

Med Microbiol Immunol. 2019 Aug;208(3-4):469-473. doi: 10.1007/s00430-019-00610-z. Epub 2019 May 10. Review.

PMID:
31076879
3.

Pediatric roots of cytomegalovirus recurrence and memory inflation in the elderly.

Adler SP, Reddehase MJ.

Med Microbiol Immunol. 2019 Aug;208(3-4):323-328. doi: 10.1007/s00430-019-00609-6. Epub 2019 May 6. Review.

PMID:
31062089
4.

Cellular reservoirs of latent cytomegaloviruses.

Reddehase MJ, Lemmermann NAW.

Med Microbiol Immunol. 2019 Aug;208(3-4):391-403. doi: 10.1007/s00430-019-00592-y. Epub 2019 Apr 22. Review.

PMID:
31011793
5.

Function of the cargo sorting dileucine motif in a cytomegalovirus immune evasion protein.

Fink A, Mikuličić S, Blaum F, Reddehase MJ, Florin L, Lemmermann NAW.

Med Microbiol Immunol. 2019 Aug;208(3-4):531-542. doi: 10.1007/s00430-019-00604-x. Epub 2019 Apr 19.

PMID:
31004199
6.

Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades' résumé.

Krmpotić A, Podlech J, Reddehase MJ, Britt WJ, Jonjić S.

Med Microbiol Immunol. 2019 Aug;208(3-4):415-429. doi: 10.1007/s00430-019-00600-1. Epub 2019 Mar 28. Review.

PMID:
30923898
7.

Coincident airway exposure to low-potency allergen and cytomegalovirus sensitizes for allergic airway disease by viral activation of migratory dendritic cells.

Reuter S, Lemmermann NAW, Maxeiner J, Podlech J, Beckert H, Freitag K, Teschner D, Ries F, Taube C, Buhl R, Reddehase MJ, Holtappels R.

PLoS Pathog. 2019 Mar 7;15(3):e1007595. doi: 10.1371/journal.ppat.1007595. eCollection 2019 Mar.

8.
9.

From basic molecular biology to curative antiviral therapy: the success story of Hepatitis C virology.

Reddehase MJ.

Med Microbiol Immunol. 2019 Feb;208(1):1-2. doi: 10.1007/s00430-018-0569-7. No abstract available.

PMID:
30328536
10.

Recent advances in CMV tropism, latency, and diagnosis during aging.

Leng SX, Kamil J, Purdy JG, Lemmermann NA, Reddehase MJ, Goodrum FD.

Geroscience. 2017 Jun;39(3):251-259. doi: 10.1007/s11357-017-9985-7. Epub 2017 Jul 5.

11.

The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription.

Chan B, Gonçalves Magalhães V, Lemmermann NAW, Juranić Lisnić V, Stempel M, Bussey KA, Reimer E, Podlech J, Lienenklaus S, Reddehase MJ, Jonjić S, Brinkmann MM.

PLoS Pathog. 2017 May 25;13(5):e1006382. doi: 10.1371/journal.ppat.1006382. eCollection 2017 May.

12.

TLR3-independent activation of mast cells by cytomegalovirus contributes to control of pulmonary infection.

Lemmermann NAW, Reddehase MJ.

Cell Mol Immunol. 2017 Jun;14(6):479-481. doi: 10.1038/cmi.2017.23. Epub 2017 May 8. No abstract available.

13.

IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection.

Popovic B, Golemac M, Podlech J, Zeleznjak J, Bilic-Zulle L, Lukic ML, Cicin-Sain L, Reddehase MJ, Sparwasser T, Krmpotic A, Jonjic S.

PLoS Pathog. 2017 Apr 27;13(4):e1006345. doi: 10.1371/journal.ppat.1006345. eCollection 2017 Apr.

14.

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors.

Dekhtiarenko I, Ratts RB, Blatnik R, Lee LN, Fischer S, Borkner L, Oduro JD, Marandu TF, Hoppe S, Ruzsics Z, Sonnemann JK, Mansouri M, Meyer C, Lemmermann NA, Holtappels R, Arens R, Klenerman P, Früh K, Reddehase MJ, Riemer AB, Cicin-Sain L.

PLoS Pathog. 2016 Dec 15;12(12):e1006072. doi: 10.1371/journal.ppat.1006072. eCollection 2016 Dec.

15.

Refining human T-cell immunotherapy of cytomegalovirus disease: a mouse model with 'humanized' antigen presentation as a new preclinical study tool.

Lemmermann NA, Reddehase MJ.

Med Microbiol Immunol. 2016 Dec;205(6):549-561. Epub 2016 Aug 18. Review.

PMID:
27539576
16.

Past, present and future of immunology in Mainz.

Waisman A, Hövelmeyer N, Diefenbach A, Schuppan D, Reddehase MJ, Kleinert H, Kaina B, Grabbe S, Galle PR, Theobald M, Zipp F, Sahin U, Türeci Ö, Kreiter S, Langguth P, Decker H, van Zandbergen G, Schild H.

Cell Immunol. 2016 Oct;308:1-6. doi: 10.1016/j.cellimm.2016.09.001. No abstract available.

PMID:
27719802
17.

Mutual Interference between Cytomegalovirus and Reconstitution of Protective Immunity after Hematopoietic Cell Transplantation.

Reddehase MJ.

Front Immunol. 2016 Aug 4;7:294. doi: 10.3389/fimmu.2016.00294. eCollection 2016. Review.

18.

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.

19.

Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance.

Holtappels R, Lemmermann NA, Podlech J, Ebert S, Reddehase MJ.

Front Immunol. 2016 Jun 14;7:232. doi: 10.3389/fimmu.2016.00232. eCollection 2016.

20.

Non-cognate bystander cytolysis by clonal epitope-specific CTL lines through CD28-CD80 interaction inhibits antibody production: A potential caveat to CD8 T-cell immunotherapy.

Holtappels R, Podlech J, Lemmermann NA, Schmitt E, Reddehase MJ.

Cell Immunol. 2016 Oct;308:44-56. doi: 10.1016/j.cellimm.2015.12.004. Epub 2015 Dec 17.

PMID:
26717854
21.

Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice.

Thomas S, Klobuch S, Podlech J, Plachter B, Hoffmann P, Renzaho A, Theobald M, Reddehase MJ, Herr W, Lemmermann NA.

PLoS Pathog. 2015 Jul 16;11(7):e1005049. doi: 10.1371/journal.ppat.1005049. eCollection 2015 Jul.

22.

Margaret Gladys Smith, mother of cytomegalovirus: 60th anniversary of cytomegalovirus isolation.

Reddehase MJ.

Med Microbiol Immunol. 2015 Jun;204(3):239-41. doi: 10.1007/s00430-015-0416-z. Epub 2015 Apr 12. No abstract available.

PMID:
25864083
23.

An endocytic YXXΦ (YRRF) cargo sorting motif in the cytoplasmic tail of murine cytomegalovirus AP2 'adapter adapter' protein m04/gp34 antagonizes virus evasion of natural killer cells.

Fink A, Blaum F, Babic Cac M, Ebert S, Lemmermann NA, Reddehase MJ.

Med Microbiol Immunol. 2015 Jun;204(3):383-94. doi: 10.1007/s00430-015-0414-1. Epub 2015 Apr 8.

PMID:
25850989
24.

Mechanism of tumor remission by cytomegalovirus in a murine lymphoma model: evidence for involvement of virally induced cellular interleukin-15.

Erlach KC, Reddehase MJ, Podlech J.

Med Microbiol Immunol. 2015 Jun;204(3):355-66. doi: 10.1007/s00430-015-0408-z. Epub 2015 Mar 25.

PMID:
25805565
25.

Identification of an atypical CD8 T cell epitope encoded by murine cytomegalovirus ORF-M54 gaining dominance after deletion of the immunodominant antiviral CD8 T cell specificities.

Holtappels R, Lemmermann NA, Thomas D, Renzaho A, Reddehase MJ.

Med Microbiol Immunol. 2015 Jun;204(3):317-26. doi: 10.1007/s00430-015-0404-3. Epub 2015 Mar 25.

PMID:
25805564
26.

Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH/gL/gO complex as a paradigm.

Podlech J, Reddehase MJ, Adler B, Lemmermann NA.

Med Microbiol Immunol. 2015 Jun;204(3):295-305. doi: 10.1007/s00430-015-0405-2. Epub 2015 Mar 18. Review.

PMID:
25782576
27.

Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.

Lemmermann NA, Krmpotic A, Podlech J, Brizic I, Prager A, Adler H, Karbach A, Wu Y, Jonjic S, Reddehase MJ, Adler B.

PLoS Pathog. 2015 Feb 6;11(2):e1004640. doi: 10.1371/journal.ppat.1004640. eCollection 2015 Feb.

28.

Mast cells: innate attractors recruiting protective CD8 T cells to sites of cytomegalovirus infection.

Podlech J, Ebert S, Becker M, Reddehase MJ, Stassen M, Lemmermann NA.

Med Microbiol Immunol. 2015 Jun;204(3):327-34. doi: 10.1007/s00430-015-0386-1. Epub 2015 Feb 4. Review.

PMID:
25648117
29.

Mast cells as rapid innate sensors of cytomegalovirus by TLR3/TRIF signaling-dependent and -independent mechanisms.

Becker M, Lemmermann NA, Ebert S, Baars P, Renzaho A, Podlech J, Stassen M, Reddehase MJ.

Cell Mol Immunol. 2015 Mar;12(2):192-201. doi: 10.1038/cmi.2014.73. Epub 2014 Aug 25.

30.

Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.

Ebert S, Becker M, Lemmermann NA, Büttner JK, Michel A, Taube C, Podlech J, Böhm V, Freitag K, Thomas D, Holtappels R, Reddehase MJ, Stassen M.

PLoS Pathog. 2014 Apr 24;10(4):e1004100. doi: 10.1371/journal.ppat.1004100. eCollection 2014 Apr.

31.

Noncanonical expression of a murine cytomegalovirus early protein CD8 T-cell epitope as an immediate early epitope based on transcription from an upstream gene.

Fink A, Büttner JK, Thomas D, Holtappels R, Reddehase MJ, Lemmermann NA.

Viruses. 2014 Feb 14;6(2):808-31. doi: 10.3390/v6020808.

32.

The p36 isoform of murine cytomegalovirus m152 protein suffices for mediating innate and adaptive immune evasion.

Fink A, Renzaho A, Reddehase MJ, Lemmermann NA.

Viruses. 2013 Dec 16;5(12):3171-91. doi: 10.3390/v5123171.

33.

The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.

Wagner FM, Brizic I, Prager A, Trsan T, Arapovic M, Lemmermann NA, Podlech J, Reddehase MJ, Lemnitzer F, Bosse JB, Gimpfl M, Marcinowski L, MacDonald M, Adler H, Koszinowski UH, Adler B.

PLoS Pathog. 2013;9(7):e1003493. doi: 10.1371/journal.ppat.1003493. Epub 2013 Jul 25.

34.

TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer.

Nauerth M, Weißbrich B, Knall R, Franz T, Dössinger G, Bet J, Paszkiewicz PJ, Pfeifer L, Bunse M, Uckert W, Holtappels R, Gillert-Marien D, Neuenhahn M, Krackhardt A, Reddehase MJ, Riddell SR, Busch DH.

Sci Transl Med. 2013 Jul 3;5(192):192ra87. doi: 10.1126/scitranslmed.3005958.

35.

Viral latency drives 'memory inflation': a unifying hypothesis linking two hallmarks of cytomegalovirus infection.

Seckert CK, Griessl M, Büttner JK, Scheller S, Simon CO, Kropp KA, Renzaho A, Kühnapfel B, Grzimek NK, Reddehase MJ.

Med Microbiol Immunol. 2012 Nov;201(4):551-66. doi: 10.1007/s00430-012-0273-y. Epub 2012 Sep 19. Review.

PMID:
22991040
36.

Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells.

Ebert S, Lemmermann NA, Thomas D, Renzaho A, Reddehase MJ, Holtappels R.

Med Microbiol Immunol. 2012 Nov;201(4):541-50. doi: 10.1007/s00430-012-0268-8. Epub 2012 Sep 14.

PMID:
22976556
37.

Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection.

Ebert S, Podlech J, Gillert-Marien D, Gergely KM, Büttner JK, Fink A, Freitag K, Thomas D, Reddehase MJ, Holtappels R.

Med Microbiol Immunol. 2012 Nov;201(4):527-39. doi: 10.1007/s00430-012-0258-x. Epub 2012 Sep 13. Review.

PMID:
22972232
38.

Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions.

Lemmermann NA, Fink A, Podlech J, Ebert S, Wilhelmi V, Böhm V, Holtappels R, Reddehase MJ.

Med Microbiol Immunol. 2012 Nov;201(4):497-512. doi: 10.1007/s00430-012-0257-y. Epub 2012 Sep 9. Review.

PMID:
22961127
39.

Antigen presentation under the influence of 'immune evasion' proteins and its modulation by interferon-gamma: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells.

Fink A, Lemmermann NA, Gillert-Marien D, Thomas D, Freitag K, Böhm V, Wilhelmi V, Reifenberg K, Reddehase MJ, Holtappels R.

Med Microbiol Immunol. 2012 Nov;201(4):513-25. doi: 10.1007/s00430-012-0256-z. Epub 2012 Sep 9.

PMID:
22961126
40.

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.

Rodríguez-Martín S, Kropp KA, Wilhelmi V, Lisnic VJ, Hsieh WY, Blanc M, Livingston A, Busche A, Tekotte H, Messerle M, Auer M, Fraser I, Jonjic S, Angulo A, Reddehase MJ, Ghazal P.

PLoS Pathog. 2012;8(8):e1002901. doi: 10.1371/journal.ppat.1002901. Epub 2012 Aug 30.

41.

The NK cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8(+) T-cell response.

Mitrović M, Arapović J, Jordan S, Fodil-Cornu N, Ebert S, Vidal SM, Krmpotić A, Reddehase MJ, Jonjić S.

J Virol. 2012 Feb;86(4):2165-75. doi: 10.1128/JVI.06042-11. Epub 2011 Dec 7.

42.

Shedding light on the elusive role of endothelial cells in cytomegalovirus dissemination.

Sacher T, Andrassy J, Kalnins A, Dölken L, Jordan S, Podlech J, Ruzsics Z, Jauch KW, Reddehase MJ, Koszinowski UH.

PLoS Pathog. 2011 Nov;7(11):e1002366. doi: 10.1371/journal.ppat.1002366. Epub 2011 Nov 17.

43.

Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency.

Seckert CK, Schader SI, Ebert S, Thomas D, Freitag K, Renzaho A, Podlech J, Reddehase MJ, Holtappels R.

J Gen Virol. 2011 Sep;92(Pt 9):1994-2005. doi: 10.1099/vir.0.031815-0. Epub 2011 Jun 1.

PMID:
21632567
44.

Single cell detection of latent cytomegalovirus reactivation in host tissue.

Marquardt A, Halle S, Seckert CK, Lemmermann NA, Veres TZ, Braun A, Maus UA, Förster R, Reddehase MJ, Messerle M, Busche A.

J Gen Virol. 2011 Jun;92(Pt 6):1279-91. doi: 10.1099/vir.0.029827-0. Epub 2011 Feb 16.

PMID:
21325477
45.

Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion.

Lemmermann NA, Kropp KA, Seckert CK, Grzimek NK, Reddehase MJ.

J Biomed Biotechnol. 2011;2011:812742. doi: 10.1155/2011/812742. Epub 2010 Dec 26. Review.

46.

In vivo impact of cytomegalovirus evasion of CD8 T-cell immunity: facts and thoughts based on murine models.

Lemmermann NA, Böhm V, Holtappels R, Reddehase MJ.

Virus Res. 2011 May;157(2):161-74. doi: 10.1016/j.virusres.2010.09.022. Epub 2010 Oct 8. Review.

PMID:
20933556
47.

Enhancerless cytomegalovirus is capable of establishing a low-level maintenance infection in severely immunodeficient host tissues but fails in exponential growth.

Podlech J, Pintea R, Kropp KA, Fink A, Lemmermann NA, Erlach KC, Isern E, Angulo A, Ghazal P, Reddehase MJ.

J Virol. 2010 Jun;84(12):6254-61. doi: 10.1128/JVI.00419-10. Epub 2010 Apr 7.

48.

A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum.

Däubner T, Fink A, Seitz A, Tenzer S, Müller J, Strand D, Seckert CK, Janssen C, Renzaho A, Grzimek NK, Simon CO, Ebert S, Reddehase MJ, Oehrlein-Karpi SA, Lemmermann NA.

J Gen Virol. 2010 Jun;91(Pt 6):1524-34. doi: 10.1099/vir.0.018580-0. Epub 2010 Feb 10.

PMID:
20147515
49.

Immune evasion proteins of murine cytomegalovirus preferentially affect cell surface display of recently generated peptide presentation complexes.

Lemmermann NA, Gergely K, Böhm V, Deegen P, Däubner T, Reddehase MJ.

J Virol. 2010 Feb;84(3):1221-36. doi: 10.1128/JVI.02087-09. Epub 2009 Nov 11.

50.

Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity.

Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA.

Gastroenterology. 2010 Jan;138(1):336-46. doi: 10.1053/j.gastro.2009.08.057. Epub 2009 Sep 6.

PMID:
19737567

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