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Items: 8


Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis.

Ibrahim ML, Klement JD, Lu C, Redd PS, Xiao W, Yang D, Browning DD, Savage NM, Buckhaults PJ, Morse HC 3rd, Liu K.

Cell Rep. 2018 Dec 11;25(11):3036-3046.e6. doi: 10.1016/j.celrep.2018.11.050.


Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy.

Xiao W, Ibrahim ML, Redd PS, Klement JD, Lu C, Yang D, Savage NM, Liu K.

Mol Cancer Res. 2019 Feb;17(2):420-430. doi: 10.1158/1541-7786.MCR-18-0455. Epub 2018 Nov 14.


An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion.

Klement JD, Paschall AV, Redd PS, Ibrahim ML, Lu C, Yang D, Celis E, Abrams SI, Ozato K, Liu K.

J Clin Invest. 2018 Dec 3;128(12):5549-5560. doi: 10.1172/JCI123360. Epub 2018 Nov 5.


H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells.

Redd PS, Lu C, Klement JD, Ibrahim ML, Zhou G, Kumai T, Celis E, Liu K.

Oncoimmunology. 2018 Jul 23;7(9):e1483302. doi: 10.1080/2162402X.2018.1483302. eCollection 2018.


SETD1B Activates iNOS Expression in Myeloid-Derived Suppressor Cells.

Redd PS, Ibrahim ML, Klement JD, Sharman SK, Paschall AV, Yang D, Nayak-Kapoor A, Liu K.

Cancer Res. 2017 Jun 1;77(11):2834-2843. doi: 10.1158/0008-5472.CAN-16-2238. Epub 2017 Apr 5.


The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells.

Lu C, Redd PS, Lee JR, Savage N, Liu K.

Oncoimmunology. 2016 Oct 20;5(12):e1247135. doi: 10.1080/2162402X.2016.1247135. eCollection 2016.


CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype.

Paschall AV, Yang D, Lu C, Redd PS, Choi JH, Heaton CM, Lee JR, Nayak-Kapoor A, Liu K.

Oncotarget. 2016 Nov 29;7(48):78698-78712. doi: 10.18632/oncotarget.12168.


Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes.

Coe GL, Redd PS, Paschall AV, Lu C, Gu L, Cai H, Albers T, Lebedyeva IO, Liu K.

Sci Rep. 2016 Aug 4;6:30816. doi: 10.1038/srep30816.

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