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Items: 12


ROS Promotes Cancer Cell Survival through Calcium Signaling.

Reczek CR, Chandel NS.

Cancer Cell. 2018 Jun 11;33(6):949-951. doi: 10.1016/j.ccell.2018.05.010.


Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells.

Naguib A, Mathew G, Reczek CR, Watrud K, Ambrico A, Herzka T, Salas IC, Lee MF, El-Amine N, Zheng W, Di Francesco ME, Marszalek JR, Pappin DJ, Chandel NS, Trotman LC.

Cell Rep. 2018 Apr 3;23(1):58-67. doi: 10.1016/j.celrep.2018.03.032.


A CRISPR screen identifies a pathway required for paraquat-induced cell death.

Reczek CR, Birsoy K, Kong H, Martínez-Reyes I, Wang T, Gao P, Sabatini DM, Chandel NS.

Nat Chem Biol. 2017 Dec;13(12):1274-1279. doi: 10.1038/nchembio.2499. Epub 2017 Oct 23.


Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

Chandel NS, Avizonis D, Reczek CR, Weinberg SE, Menz S, Neuhaus R, Christian S, Haegebarth A, Algire C, Pollak M.

Cell Metab. 2016 Apr 12;23(4):569-70. doi: 10.1016/j.cmet.2016.03.010. No abstract available.


The Mitochondrial Respiratory Chain Is Required for Organismal Adaptation to Hypoxia.

Hamanaka RB, Weinberg SE, Reczek CR, Chandel NS.

Cell Rep. 2016 Apr 19;15(3):451-459. doi: 10.1016/j.celrep.2016.03.044. Epub 2016 Apr 7.


The DNA resection protein CtIP promotes mammary tumorigenesis.

Reczek CR, Shakya R, Miteva Y, Szabolcs M, Ludwig T, Baer R.

Oncotarget. 2016 May 31;7(22):32172-83. doi: 10.18632/oncotarget.8605.


CANCER. Revisiting vitamin C and cancer.

Reczek CR, Chandel NS.

Science. 2015 Dec 11;350(6266):1317-8. doi: 10.1126/science.aad8671. No abstract available.


ROS-dependent signal transduction.

Reczek CR, Chandel NS.

Curr Opin Cell Biol. 2015 Apr;33:8-13. doi: 10.1016/ Epub 2014 Oct 8. Review.


CtIP-mediated resection is essential for viability and can operate independently of BRCA1.

Polato F, Callen E, Wong N, Faryabi R, Bunting S, Chen HT, Kozak M, Kruhlak MJ, Reczek CR, Lee WH, Ludwig T, Baer R, Feigenbaum L, Jackson S, Nussenzweig A.

J Exp Med. 2014 Jun 2;211(6):1027-36. doi: 10.1084/jem.20131939. Epub 2014 May 19.


The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression.

Reczek CR, Szabolcs M, Stark JM, Ludwig T, Baer R.

J Cell Biol. 2013 May 27;201(5):693-707. doi: 10.1083/jcb.201302145.


Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.

Bothmer A, Rommel PC, Gazumyan A, Polato F, Reczek CR, Muellenbeck MF, Schaetzlein S, Edelmann W, Chen PL, Brosh RM Jr, Casellas R, Ludwig T, Baer R, Nussenzweig A, Nussenzweig MC, Robbiani DF.

J Exp Med. 2013 Jan 14;210(1):115-23. doi: 10.1084/jem.20121975. Epub 2012 Dec 17.


BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.

Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T.

Science. 2011 Oct 28;334(6055):525-8. doi: 10.1126/science.1209909.

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